Anda di halaman 1dari 14

15th Jakarta Antimicrobial Update 2014

in conjunction with

20 Congress of Indonesian Society of Tropical Medicine


and Infectious Disease Consultant
th

Infectious Disease: From Global Issue to Local Practice

Workshops
Meet the Expert
Plenary Lecture
Symposia
Lunch Symposia

Saturday to Sunday, 26th - 27th, April, 2014

Shangri-La Hotel, Jakarta

FINAL ANNOUNCEMENT

Dear Colleagues,
The progression of medical science, specially in tropical medicine and infectious disease
should be watched well. How to approach patients use from bench to bedside philosophy
should be completed with the understanding of how to implement the global issue to the
local practice.
The Division of Tropical Medicine and Infectious Disease, Department of Internal
Medicine, Faculty of Medicine University of Indonesia and The Indonesian Society of
Tropical Medicine and Infectious Disease Consultant (PB PETRI), proudly present
and honored to invited you to the 15th Jakarta Antimicrobial Update (JADE) which be
held on Saturday to Sunday, April, 26th - 27th 2014 at Shangri-La Hotel, with the title of
Infectious Disease : From Global Issue to Local Practice
All of topics are selected to improve our knowledge related to actual issue and to fulfill the
needs of basic to advance information in tropical medicine and infectious disease. In this
symposium, experts will share their experience in their field which is included the major
problem of multi drugs resistant microorganism, tropical disease global problem, actual
sepsis approach and any other worldwide infectious diseases issue that can lead you to do
better in your daily practice based on medical evidence.
We hope your attendance and hope that you can enjoy it all.
Best regards.
Dr. dr. Leonard Nainggolan, SpPD-KPTI

CONGRESS OVERVIEW
Date

: Saturday to Sunday, 26th - 27th, April, 2014

Venue

: Shangri La Hotel, Jl. Jend. Sudirman, Jakarta

Participants : 1.000 GPs / Specialists


Programs



Workshops
Meet the Expert
Plenary Lecture
Symposia
Lunch Symposia

Secretariat:
Organized JADE 2014
Pic: Leni Sibarani, Rita H, Nelly S, Julianto MP
Division of Tropical Medicine and Infectious Disease Department of IPD-FKUI / RSCM
Phone: +6221 3911873, +6221 3920185
Fax: +6221 3929106
E-mails: jade_update@yahoo.com, lenisibarani@yahoo.com

STEERING COMMITTEE
Chair of Department IPD - FKUI / RSCM
Chair of CME IPD FKUI / RSCM
Board of PETRI JAYA
Chair of Division Tropical Infectious Disease, Department IPD - FKUI / RSCM

ORGANIZING COMMITTEE
Chairman

: Prof. dr. Djoko Widodo, SpPD-KPTI

Vice Chair

: Dr. dr. Leonard Nainggolan, SpPD-KPTI

Executive Secretary

: dr. Ronald Irwanto SpPD-KPTI

Treasurer

: Prof. dr. Herdiman T. Pohan, SpPD-KPTI


dr. Erni Juwita Nelwan, SpPD-KPTI

Scientific Program



Executing Events

: dr. Adityo Susilo, SpPD


dr. Edwin Leopold Jim, SpPD

Registration

: Dr. dr. Widayat D Santoso, SpPD-KPTI


dr. Rika Bur, SpPD

Secretariat


Dr. dr. Suhendro, SpPD-KPTI


dr. Budi Setiawan, SpPD-KPTI
dr. Kie Chen, SpPD-KPTI
dr. Ifael Yerosias Mauleti, SpPD
dr. Eppy, SpPD

Leni Sibarani
Rita Heryati
Julianto M. P
Nelly Sri H

SCIENTIFIC PROGRAMS
15 Jakarta Antimicrobial Update 2014
th

in conjunction with

20th Congress of Indonesian Society of Tropical Medicine


and Infectious Disease Consultant

Infectious Disease: From Global Issue to Local Practice

Saturday, 26th April 2014


TIME

EVENT

07.00 - 07.30 REGISTRATION


Meet the Expert 1
Rationale Antibiotic Usage:
07.30 - 08.00 based on guidelines
Case Presentation
08.00 - 08.30 Lecturer Guide: Suhendro
Room: Ballroom A
08.30 - 09.00 Opening Ceremony

Meet the Expert 2


Meet the Expert 3
Acute Diarrhea: clinical Strategy to Combat the
spectrum and treatment Opportunistic Infection in
HIV Patient
Case Presentation
Case Presentation
Lecturer Guide: Ronald Lecturer Guide:
Irwanto
Erni J. Nelwan
Room: Ballroom B
Room: Ballroom C

08.30 - 08.40 Chairman of Organizing Committee 15th JADE 2014


08.40 - 08.50 Chairman of PB PETRI
08.50 - 09.00 Chairman of Department of Internal Medicine, Faculty of Medicine,
University of Indonesia
09.00 - 10.30 PLENARY LECTURE
Moderator: Djoko Widodo
09.00 - 09.30 * Plenary Lecture 1
Integrated Review of Imunopathogenesis in Dengue Infection
Byron Martina (Holland)
09.30 - 10.00 * Plenary Lecture 2
Infectious Diseases Laboratory Diagnostic: the role of nanotechnology
Yasua Suda (Japan)
10.00 - 10.30 * Plenary Lecture 3
Relapse and its Prevention: risk of serious illness versus primaquine toxicity
Kevin Baird (France)
Room: Ballroom B
10.30 - 10.45 Coffee Break & Visit the Exhibition Stand

Meet the Expert 4


Dengue Infection Management
Case Presentation
Lecturer Guide: Leonard
Nainggolan
Room: Sumatera & Bali room

SCIENTIFIC PROGRAMS
TIME

EVENT

Symposia 1
Management
of Complicated
10.45 - 12.00 Intra Abdominal
Infection (cIAI)
Moderator:
Suhendro
* Surgical
Treatment in cIAI
10.45 - 11.05
Arnold Simanjuntak

Symposia 2
Management
of Community
Acquired
Pneumonia (CAP)
Moderator:
Djoko Widodo
* The New Update
of Indonesia
Guideline for CAP
Cleopas Martin
Rumende
* Severe cIAI
* PK/PD of
Treatment: role of Levofloxacin
11.05 - 11.25 Tygecycline
Oloan Tampubolon Sulistia / Arini
(farmako fkui)
* The Clinical
Experience Using
Respiratory
11.25 - 11.45
Quinolone: the
role of oral 750mg
levofloxacin
Khie Chen
11.45 - 12.00 * Discussion
* Discussion
Room: Ballroom A
Room: Ballroom B

12.00 - 13.15

Symposia 5
Symposia 6
Ventilator Acquired ESBL Management:
Pneumonia (VAP)
role of ertapenem

Moderator:Iskandar
Zulkarnaen
* Diagnosis & Risk
Assessment of
12.00 - 12.20 VAP
Cleopas Martin
Rumende
* MDR/XDR/PDR the
Microorganism of
12.20 - 12.40 Pattern in VAP

Moderator:
Budi Setiawan
* What is ESBL?
Latre Buntaran
* Managing ESBL
in cIAI

Anis Karuniawati
Khie Chen
* Treatment of VAP * Managing ESBL in
12.40 - 13.00
Complicated UTI
Erni J. Nelwan
Herdiman T. Pohan
13.00 - 13.15 * Discussion
* Discussion
Room: Ballroom A Room: Ballroom B
13.15 - 14.15 Lunch, Pray & Visit the Exhibition Stand

Symposia 3
Symposia 4
Managing the Surgical The Role of Co-enzym Q-10
Side Infection (SSI)
in Infectious Disease

Work Shop 1
RATIONAL
ANTIBIOTICS
USAGE

Moderator:
Budi Setiawan
* Emerging Problem
of SSI

Moderator: Usman Hadi

Latre Buntaran,
Uun Sumardi

SH Manullang

Rianto Setiabudi

* Topical Wound
Treatment of SSI

* The Clinical Use of Coenzym Q-10 in Infectious


Disease
Nasronudin

Suhartono

* What is Co-enzym Q-10?

* Managing SSI: the


role of moxifloxacin

Erni J. Nelwan
* Discussion
Room: Ballroom C

* Discussion
Room: Sumatera &
Bali room
Symposia 7
Symposia 8
Managing the Urinary Point of Care Testing in
Tract Infection in Daily Infectious Disease and
Practice
Related Illness
Moderator: Suhendro Moderator:
Bachti Alisyahbana
* Clinical & Laboratory * Rapid Diagnostic Test in
Aspect of UTI
Infectious Disease: how
its work?
Rudi Wisaksana
Bruce Malclom
* Complicated UTI:
how to diagnose &
manage?
Franciscus Ginting
* Antibiotics Evidence
for UTI
Armen Ahmad
* Discussion
Room: Ballroom C

* Case Discussion
Room: Sulawesi
Work Shop 2
MALARIA
Bryan K.S. Yeung,
Paul N. Harijanto

* Clinical Implementation
of Rapid Diagnostic Test
in Infectious Disease and
Related Illness
Bachti Alisyahbana

* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

SCIENTIFIC PROGRAMS
TIME

EVENT
Symposia 9
Typhoid Fever in
Daily Practice

14.15 - 15.30
Moderator:
Leonard
Nainggolan
* Diagnosis &
Pathogenesis of
14.15 - 14.35 Typhoid Fever
Agung Nugroho
* Treatment of
Typhoid Fever:
the role of
14.35 - 14.55
Levofloxacin
Sudirman Katu

Symposia 10
Microorganism
Producing
Carbapenemase:
how to manage?
Moderator:
Suhendro

Symposia 11
Managing Gram
Negative Infection

Symposia 12
Paracitic Infection in
Immunocompeten and
Immunocompromized Patient

Moderator:
Djoko Widodo

Moderator:
Sjamsuridjal Djauzi

* Microbiological
Aspect of
Carbapenemase

* Eradicating Gram
Negative Infection:
the role of
cephalosporin
Iman Firmansyah
* Managing the
Severe Gram
Negative Infection:
the role of
meropenem
Tatar Sumandjar

* Paracitic Infection: how to


diagnose?

Yeva Rosana
* Managing
Microorganism
Producing
Carbapenemase

Ronald Irwanto
* Clinical Experience
Using Astreonam
for Eradicating the
14.55 - 15.15
Microorganism
Producing
Carbapenemase
Herdiman T. Pohan
15.15 - 15.30 * Discussion
* Discussion
* Discussion
Room: Ballroom A Room: Ballroom B
Room: Ballroom C
15.30 - 15.45 Coffee Break & Visit the Exhibition Stand

Work Shop 3
TYPHOID FEVER
Niniek Budiarti,
Boerhan
Budi Setiawan

Prof Teguh
* Managing Paracitic
Infection in
Immunocompeten and
Immunocompromized
Patient
Suresh Kumar (Malaysia)

* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

SCIENTIFIC PROGRAMS
TIME

EVENT
Symposia 13
Malaria Infection

15.45 - 17.00

15.45 - 16.05

16.05 - 16.25

16.25 - 16.45

16.45 - 17.00
17.00-selesai

Symposia 14
Concerning the New
Emerging Infectious
Diseases: how to
diagnose faster?
Moderator:
Djoni Djunaedi
* MERS-CoV

Symposia 15
Rubella Infection

Moderator:
Moderator:
Carta Gunawan
Halim Mubin
* Molecular based
* How to Diagnose
pathogenesis in
Rubella?
Malaria
Kevin Baird (France) Nasronudin
Doni Priambodo
* Treatment of
* Avian Influenza
* Managing the
Malaria and the
Rubella Infection:
challenge now a
the role of
days in Indonesia
immunomodelator
P. N. Harijanto
Anna Anggraini
Nanang Sukmana
Improving Malaria * Lyssa Virus/Rabies * Rubella in
treatment through
Pregnancy: what
Robust Drug
should we do?
development
Carta Gunawan
I Ketut Agus Somia Rachmat Latief
* Discussion
* Discussion
* Discussion
Room: Ballroom A Room: Ballroom B
Room: Ballroom C
ORGANIZATION MEETING PB. PETRI & BRANCH

Symposia 16
Phylosophy in ARV
Management

Work Shop 4
SEPSIS

Moderator:
Djoko Widodo
* How to Choose the ARV?

Suhendro,
Tatar Sumandjar

I.K. Tuti Parwati Merati


* How to Predict the ARV
Resistance?
Muchlis Achsan Udji Sofro
* Recent Management of
ARV in HIV Patient
Erni J. Nelwan
* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

SCIENTIFIC PROGRAMS
Sunday, 27 April 2014
th

TIME

EVENT

07.00 - 08.00 REGISTRATION


Meet the Expert 5
How to Choose
08.00 - 09.00 the Antimicrobial
Treatment in Febrile
Neutropenia
08.00 - 08.30 Case Presentation
08.30 - 09.00 Lecturer Guide: Khie
Chen
Room: Ballroom A

Meet the Expert 6 Meet the Expert 7


Managing MDR/
Leptospirosis
XDR/PDR Sepsis
Overview
in ICU

Meet the Expert 8


Fever of Unknown Origin (FUO): diagnosis and
management

Case Presentation
Lecturer Guide:
Suhendro
Room: Ballroom B

Case Presentation
Lecturer Guide:
Hussein Gasem
Room: Ballroom C

Case Presentation
Lecturer Guide: Budi Riyanto

Symposia 18
Management
of Systemic
Fungal Infection
(SFIs): focus on
candidemia

Symposia 19
The Good News
in Herpes Zoster
Prevention

Symposia 20
Propolis Extract in Dengue
Infection

Moderator:
I.K. Tuti Parwati
Merati
* Candidemia Risk
Assessment &
Diagnosis

Moderator:
Usman Hadi

Moderator: Djoko Widodo

* Vaccination for
Adult: What is
recommended

* Pharmacology Aspects of
Extract Propolis in Dengue
Infection

Suhendro
* Microbiology
Aspect of
Candida sp.

Iris Rengganis
The Issues of Herpes
Zoster Vaccination

Aznan Lelo
* The Role of Cytokine in
Dengue Infection

Retno
Wahyuningsih
* Treatment of
Candidemia

Erni J Nelwan

Leonard Nainggolan

Herpes Zoster
Vaccine - Clinical
Data

Khie Chen
* Discussion
Room: Ballroom B

Samsuridzal Djauzi
* Discussion
Room: Ballroom C

* Clinical Trial and


Effectiveness of Propoelix
Repairing Clinical Condition
in Dengue Infection
Soroy Lardo
* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

Room: Sumatera & Bali room

09.00 - 10.00 PLENARY LECTURE


Moderator: Guntur Hermawan
09.00 - 09.30 * Plenary Lecture 4
Global Policy of Anti Retro Viral (ARV)
Nick Day (England)
09.30 - 10.00 * Plenary Lecture 5
How to Differentiate the Viral Infection?
Nasronudin
Room: Ballroom B
10.00 - 10.15 Coffee Break & Visit the Exhibition Stand
Symposia 17
Hospital Acquired
Pneumoniae: the
Methicillin Resistant
Staphylococcus
10.15 - 11.30
aureus (MRSA)
Infection
Moderator:
Herdiman T. Pohan
* Epidemiology of
Hospital Acquired
10.15 - 10.35 Pneumoniae
Caused by MRSA
Latre Buntaran
* Clinical Diagnosis
& Pathogenesis
of MRSA in Lung
10.35 - 10.55
Infection
Ceva Wicaksono
Pitoyo
* Eradicating the
MRSA-HAP: the role
10.55 - 11.15 teicoplanin
Ronald Irwanto
11.15 - 11.30 * Discussion
Room: Ballroom A

Work Shop 5
INFLUENZA
Kurnia Fitri Jamil,
Usman Hadi

SCIENTIFIC PROGRAMS
TIME

11.30-12.45

11.30 - 11.50

11.50 - 12.10

12.10 - 12.30

12.30 - 12.45
12.45 - 13.45

13.45 - 15.00

EVENT
Symposia 21
The Role of
Immunomodulator in
Infectious Diseases

Symposia 22
Clinical Use of
Fluor Quinolone:
focus on
moxifloxacin
Moderator:
Moderator:
Iskandar Zulkarnaen Suhendro
* Immunomodulator: * PK/PD of Fluor
how it works?
Quinolone
Iris Rengganis
* Immunomodulator
in Viral Diseases

Rianto Setiabudi
* The Use of
Moxifloxacin
in cIAI
Adityo Susilo
Khie Chen
* Immunomodulator * The Role of
for HIV Patients: is
Moxifloxacin in
there any role?
Respiratory Tract
Infection
Erni J. Nelwan
Rudi Wisaksana
* Discussion
* Discussion
Room: Ballroom A
Room: Ballroom B
Luncheon & Visit Exhibition Stand
Symposia 25
Symposia 26
Managing Diarrhea
Dengue Infection
in Daily Practice

Symposia 23
Adjuvant Therapy in
Infectious Disease

Symposia 24
Eradicating Extended Beta
Lactamase: the role of
meropenem

Moderator:
P. N. Harijanto
* The Role of
Megestrol Acetate
in Infectious
Disease
Erni J Nelwan
* The Role of NAcetyl Sistein in
Infectious Disease
Nasronudin

Moderator: Suharto

* Discussion
Room: Ballroom A

* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

Symposia 27
Hemato-oncology
Infection
Problem: focus
on pseudomonas
infection
Moderator: Suharto

Symposia 28
Microbiological and
Biomolecular Aspects of
Sepsis (in Organized with
Indonesian Sepsis Society)

Work Shop 7
MANAGING
THE AIDS
OPPORTUNISTIC
INFECTION

Moderator: Suhendro

Erni J. Nelwan,
Ronald Irwanto

Moderator:
Moderator:
Usman Hadi
Budi Setiawan
* Biomembrane:
* How to Diagnose * Febrile
nanotechnology for Dengue Infection Neutropenia:
antibiotic treatment in Primary Care?
magnitude of the
13.45 - 14.05
problem
Sukma Nuswantara Sudirman Katu
Dody Ranuhardi
(LIPI)

Work Shop 6
FEVER
Leonard
Nainggolan,
Rizka
Humardewaanti

* ESBL Pneumoniae: how to


manage?
Cleopas Martin Rumende
* Meropenem for ESBL in
cIAI: is it appropriate?
Guntur Hermawan

* Microbiological Aspects
of Sepsis
Amin Subandrio

SCIENTIFIC PROGRAMS
TIME

EVENT

* Managing Acute
* Recent
* Ceftazidime in
Bacterial Diarrhea in Pathogenesis
Malignancy with
Daily Practice
& Diagnosis of
Sepsis: is that still
14.05 - 14.25
Dengue Infection any role?
Bachti Alisyahbana
Widayat Djoko
Khie Chen
Santoso
* Cronic Diarrhea:
* Fluid Therapy in * The 4th Gen of
how to approach?
Dengue Infection Cephalosporine in
Febrile Netropenia:
14.25 - 14.45
why we choose?
Kurnia Fitri Jamil
Leonard
Primal Sujana
Nainggolan
14.45 - 15.00 * Discussion
* Discussion
* Discussion
Room: Ballroom C
Room: Ballroom A Room: Ballroom A
Symposia 29
Symposia 30
Symposia 31
Clostridium Difficile Sepsis Overview
Weil Disease
Associated Diarrhea (in Organized with
(CDAD)
Indonesian Sepsis
15.00 - 16.15
Society)
Moderator:
Moderator:
Moderator:
Gatoet Ismanoe
Herdiman T. Pohan Iskandar Zulkarnaen

* Biomolecular Aspects of
Sepsis: what is important?

* Clinical Diagnostic * Update


& Pathogenesis of
Pathogenesis on
15.00 - 15.20 CDAD
Sepsis
Marcellus
Dhani Redhono
Simadibrata
* Laboratory
* Sepsis Bundles
Diagnostic of CDAD in ICU
15.20 - 15.40

* Diagnosis &
Pathogenesis of
Weil Disease
Iman Firmansyah

* The Pathogenesis of
Amebiasis

* Treatment of Weil
Disease: the role of
meropenem
Hussein Gasem

* Clinical Aspect & Laboratory


Diagnostic of Amebiasis

Dalima Astrawinata Rudyanto


* Treatment of CDAD * Choosing
Antibiotics for
15.40 - 16.00
Sepsis
Khie Chen
Tatar Sumandjar
* Discussion
* Discussion
16.00 - 16.15 Room: Ballroom A
Room: Ballroom C
16.15 - 16.45 CLOSING REMARK

* Discussion
Room: Indonesian
room

Guntur Hermawan

* Discussion
Room: Sumatera & Bali room
Symposia 32
Update on Amebiasis

Moderator:
Yosia Ginting

* Case Discussion
Room: Sulawesi
Work Shop 8
DENGUE
INFECTION
Leonard
Nainggolan,
Widayat Djoko
Santoso

Adityo Susilo

Sjaiful I. Biran
* Treatment of Amebiasis
Sudirman Katu
* Discussion
* Case Discussion
Room: Sumatera & Bali room Room: Sulawesi

REGISTRATION FEE
WORKSHOP PER ITEM
Catagory
Specialist
General Practitioner

Rp. 2.000.000.Rp. 1.500.000.-

SYMPOSIUM
Catagory
Specialist
General Practitioner
Student

before: 1st April 2014


Rp. 1.750.000.Rp. 1.250.000.Rp. 750.000.-

1st April 2014 onsite


Rp. 2.500.000.Rp. 2.000.000.Rp. 1.000.000.-

WORKSHOP + SYMPOSIA
Catagory
Specialist
General Practitioner

METHOD OF PAYMENT:
The payment should be address to:
Prof. Dr. Herdiman T. Pohan / Erni Juwita Nelwan
Bank Mandiri - KCP Jakarta RSCM No. 122.00.0590223.7

HOTEL:
HOTEL SHANGRI-LA, JAKARTA

Samasta Tour & Travel (Pic. Ms. Vanesa)


Istana Harmoni Apartement 2H
Komplek Harmoni Plaza
Jl. Suryopranoto No. 2, Jakarta 10130
Telp. 021 63865577 (hunting)
Fax.: 021 - 63865578
E-mail: vanessa@samastatour.com

Deluxe Room Rp. 2.250.000/nett/room/night


The payment should be address to:
PT. Samasta Wisata
BCA Cab. Grand Indonesia
No. 541.530.7877

Rp. 3.500.000.Rp. 3.000.000.-

REGISTRATION & PAYMENT


Name : (Prof/DR/Dr) ..........................................................................Official Purpose Only
Full Address : ...................................................................................................................................
...................................................................................................................................
Phone / HP : ...................................................................................................................................
Fax. : ...................................................................................................................................
Email : ...................................................................................................................................
Specialist/GP : ...................................................................................................................................

WORKSHOP PER ITEM


Catagory
Specialist

Rp. 2.000.000.-

General Practitioner

Rp. 1.500.000.-

SYMPOSIUM
Catagory

before: 1st April 2014

1st April 2014 onsite

Specialist

Rp. 1.750.000.-

Rp. 2.500.000.-

General Practitioner

Rp. 1.250.000.-

Rp. 2.000.000.-

Student

Rp. 750.000.-

Rp. 1.000.000.-

WORKSHOP + SYMPOSIA
Catagory
Specialist

Rp. 3.500.000.-

General Practitioner

Rp. 3.000.000.-

METHOD OF PAYMENT:
The payment should be address to:
Prof. Dr. Herdiman T. Pohan / Erni Juwita Nelwan
Bank Mandiri - KCP Jakarta RSCM No. 122.00.0590223.7

T II M
M II P
PE
EN
N
T
IMIPENEM 0.5 G + CYLASTATINE 0.5 G

IMIPENEM
IMIPENEM 0.5
0.5 G
G ++ CYLASTATINE
CYLASTATINE 0.5
0.5 G
G

CE
EP
PT
T II K
K
C

CEFIXIME

CEFIXIME
CEFIXIME

OXTERCID
OXTERCID
CEFUROXIME 750 mg

CEFUROXIME
CEFUROXIME 750
750mg
mg

SSTTAARRXXOONN M
MEERROOBBAT
AT
CEFTRIAXONE
CEFTRIAXONE
1G
1G

MEROPENEM
MEROPENEM

SECRETARIAT
Organized JADE 2014
Pic: Leni Sibarani, Rita H, Nelly S, Julianto MP
Division of Tropical Medicine and Infectious Disease Department of IPD-FKUI / RSCM
Phone: +6221 3911873, +6221 3920185 Fax:+6221 3929106
E-mails: jade_update@yahoo.com, lenisibarani@yahoo.com