Vaccinesare:
Pharmaceuticalproducts:biologicals
Actingbystimulatingtheimmunesystem,
Mostlyprophylactic,usedto preventthe
adventofacommunicabledisease.
Louis Pasteur used rabbits for the production of the immunogen of rabies vaccine
1930
Theconceptofwellcharacterizedbiologicisrecentandevolving
Vaccines are the most important contributors to global health
improvement,onlysecondtocleanwaterandsanitation
ModernvaccineR&D,productionandvaccinationprovideasignificantand
sustainablesourceofemploymentacrosspublicandprivateinstitutions
Fundamentals of VaccineManufacturing
Drivers of VaccineAcceptability
-prescribersandendusers.
1. Disease epidemiology
2. Burden of disease
3. Public perception of the disease
4. Vaccine clinical effectiveness and safety
5. Vaccine cost-effectiveness
6. Recommendations by other influencers
Sources: Duclos et al., 2011 - Smith, J.C., 2010 - Berndt et al., 2009 - Bryson et al., 2010
2.
Sources: Levine et al., 2011 - McNeill Jr., 2011 - Hall, 2010 - Gessner et al., 2010 - Lindley et al., 2009
2. Consumer-related Concerns
1. Perceived vulnerability to the disease
2. Perceived attitude towards vaccination
3. Self-efficacy in engaging vaccination discussion
Lexington - Thundering herd - Californias anti-vaccine brigade and the dark side of individualism
Sep 26th 2015 | The Economist
Sources: Leask J. (2011) Target the fence-sitters. Nature 473; 443-45. http://www.hpa.org.uk/hpr/news/
Yet another
vaccine?!
Thank You!
Pierre A. Morgon
PharmD LL.M MBA
Chief ExecutiveOfficer
pierre@ajbiologics.com
pierremorgon