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Medicines That Can Cause Diarrhea

Many medicines can cause diarrhea, including:

Antibiotics, such as ampicillin, amoxicillin, clindamycin, tetracycline, and


cephalosporins. Diarrhea is of particular concern if you have recently been
hospitalized and received intravenous (IV) antibiotics.
Antidepressants, such as fluoxetine (Prozac) or sertraline (Zoloft).
Angiotensin-converting enzyme (ACE) inhibitors, such as captopril
(Capoten) or enalapril (Vasotec).
Antacids containing magnesium.
Colchicine.
Corticosteroid treatment, such as prednisone.
Digoxin.
Diuretics, such as furosemide or thiazides.
Laxatives, such as Correctol, Dulcolax, Ex-Lax, or Feen-a-Mint.
Medicines to prevent organ transplant rejection.
Medicines used to treat cancer (chemotherapy).
Metformin.
Propranolol, such as Inderal.
Radiation therapy.
Quinidine, such as Cardioquin or Quin-Release.
Theophylline, such as Theo-24.

Medications causing constipation


Medications that can cause constipation include
pain medications, especially narcotics
antacids that contain aluminum and calcium
calcium channel blockers, which are used to treat high blood pressure
and heart disease
medications that treat Parkinsons diseasea disorder that affects nerve
cells in a part of the brain that controls muscle movementbecause
these medications also affect the nerves in the colon wall
antispasmodicsmedications that prevent sudden muscle contractions
some antidepressants
iron supplements
diureticsmedications that help the kidneys remove fluid from the blood
anticonvulsantsmedications that decrease abnormal electrical activity
in the brain to prevent seizures

Constipation can also be caused by overuse of over-the-counter laxatives.


A laxative is medication that loosens stool and increases bowel
movements. Although people may feel relief when they use laxatives, they
usually must increase the dose over time because the body grows reliant
on laxatives to have a bowel movement. Overuse of laxatives can decrease
the colons natural ability to contract and make constipation worse.
Continued overuse of laxatives can damage nerves, muscles, and tissues
in the large intestine.

Medicines That Can Cause Headache


Sometimes prescription and nonprescription medicines can cause
headaches, especially if you use them regularly. Medications that may
cause headaches include:

Birth control pills (oral contraceptive).


Blood-thinning medicines, such as warfarin, heparin, or aspirin.
Caffeine (or caffeine withdrawal).
Heart and blood pressure medicines, such as nitroglycerin.
Cold medicines, such as antihistamines and decongestants.
Corticosteroids, such as prednisone
Ergotamine (Cafergot) therapy.
Hormone therapy, such as estrogen or progestin.
Medicines to prevent organ transplant rejection.
Medicines used to treat cancer (chemotherapy).
Overuse of fat-soluble vitamins, such as vitamin A and vitamin D.
Radiation therapy.

Medicines That Can Cause Pancreatitis


In rare cases, medicines may cause inflammation of the pancreas
(pancreatitis). These include:

Some antibiotics (such


as metronidazole, tetracycline, sulfamethoxazole andtrimethoprim,
and nitrofurantoin).
Some medicines that suppress the immune system (such as 6mercaptopurine and azathioprine).

Some medicines used to treat high blood pressure (such as ACE


inhibitors).
5-aminosalicylic acid (used to treat inflammatory bowel disease).
Some diuretics.
Corticosteroids.
Estrogen.
Some medicines used to treat diabetes (such as exenatide and sitagliptan).
Valproate (used to treat seizure disorders).
Certain general anesthetics.
Antidepressants, such as venlafaxine (Effexor).

Common Photosensitising
Medications
Antibiotics

Tetracyclines

Fluoroquinolones e.g. ciprofloxacin

Sulfonamides

Ibuprofen

Naproxen

Ketoprofen

Celecoxib

Frusemide

Bumetanide

Hydrochlorothiazide

Isotretinoin
Acitretin

Hypoglycaemics

Sulfonylureas (e.g. glipizide,


glyburide)

Neuroleptics (anticonvulsants)

Phenothiazines (e.g. chlorpromazine,


fluphenazine)

Thioxanthenes (e.g. chlorprothixene)

Nonsteroidal anti-inflammatory
drugs (NSAIDs)

Diuretics

Retinoids

PDT Pro-photosensitisers

Other drugs

5-aminolevulinic acid
Methyl-5-aminolevulinic acid

Photofrin

Amiodarone

Diltiazem

Quinine

Quinidine
Hydroxychloroquine

Enalapril
Dapsone

Common Photosensitising Topical Agents


Sunscreens

Fragrances

Miscellaneous

Benzophenones
Para-aminobenzoic acid (PABA)

Cinnamates

Salicylates

Musk

6-methylcoumarin

5-Fluorouracil (oral and topical)


Coal tar

Prepared By
Dr.Fatima Arain
(Pharm-D)
The University Of Faisalabad Pakistan