S/S: tremors, muscle rigidity and bradykinesia (slow movement), Pill Rolling,
Hypophonia (low vol of speech), micrographia (small handwriting)
Dopamine cannot cross the blood brain barrier but levodopa can and once across it is
converted to dopamine. protein affects its absorption.
NI: frim bed w/o pillow
Guillain-Barre Syndrome
Inflammation and demyelination of PNS caused by autoimmune response to some type of
viral infection or to certain vaccines. Affects all ages
Causes progressive muscle weakness and paralysis in all ages. Starts in lower and moves
up.
Tx: Plasmapheresis: plasma is removed and washed to remove antibodies bc they attack
schwann cells.
NI: monitor respiratory status and sign of hypoxia
Meningitis
S/S Increased temp, sever headache, nuchal rigidity (stiff neck)
Bacterial: spread per direct contact: Kernigs and Brudzinski
Kernigs: inability to extend leg when thigh is flexed on abs
Brudzinski: flexion of the neck produces flexion of the knees and hip
CSF is norm clear, bacteria causes it to become purulent
Multiple Sclerosis
T cells found in spinal fluid. T cells defend against intruders. In MS T cells attack their
own body
Demyelination: myelin sheath and cells are destroyed. Hard plaque like lesions replace
the destroyed myelin.
Periods of remission and exacerbation
Assessment: Pain is not common, Diplopia (double vision), seeing spots, blindness,
nystagmus, dysphagia.
NI: High fiber, change pos freq, exercise and bedrest, Avoid Heat
Alzheimers
Loss of the ability to perform tasks that require ACh