DRUG STUDY

MEDICATION DRUG INDICATION / MECHANISM DOSING & ADVERSE NURSING

CLASSIFICATION CONTRAINDICATION OF ACTION ADMINISTRATION EFFECTS RESPONSIBILITIES
esomeprazole Proton Pump Indications: Suppresses gastric tablet: CNS: Assess for
magnesium Inhibitor acid secretion by 20 mg PO OD Headache, vertigo hypersensitivity to any
(Nexium) -Treatment of GERD- specific inhibition ( for healing of Dizziness, insomnia proton pump inhibitor or
heartburn and other of the hydrogen- symptomatic Apathy, anxiety hepatic impairment.
symptoms potassium ATPase gastroesophageal Paresthesias
-Short-term treatment enzyme system at reflux disease) Dream Obtain baseline liver
for erosive esophagitis the secretory abnormalities function tests and
-As part of combination surface of the monitor periodically
treatment for duodenal gastric parietal Respiratory: during the course of
ulcer associated with cells; blocks the URI symptoms therapy.
Helicobacter pylori final step of the Sinusitis
acid production. Cough, epistaxis Instruct patient to take
Contraindications: drug at least 1 hr before
Dermatologic: meals.
-Contraindicated with Rash, inflammation
hypersensitivity to Urticaria, pruritus Instruct patient to report
omeprazole, Alopecia, dry skin severe headache,
esomeprazole, or other worsening of symptoms,
proton pump inhibitors. GI: fever, chills, darkening
Diarrhea, nausea of the skin, changes in
-Use cautiously with Abdominal pain color of urine or stool.
hepatic dysfunction, Vomiting
pregnancy, and Constipation For GI symptoms such as
lactation. Dry mouth nausea and vomiting,
Tongue atrophy instruct patient to have
Flatulence small, frequent meals.

Instruct patient to limit

activities to those that
do not require alertness
and precision as the drug
may cause vertigo and
dizziness.

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