b. T- lymphocyte
c. monocyte
b. d-Macrophage
8. Immunity through placenta is:
a. natural active immunity
b. Artificial active immunity
c. Natural passive immunity
d. Artificial passive immunity
9. One of the primary lymphoid organs:
a. spleen
b. Tonsils
c. Thymus gland
d. Lymph nodes
10. Its a memory of T cell mediated immunity:
a. T helper
b. T suppressor
c. T- cytotoxic
d. T effector
11. all are character of primary immune response
except:
a. stimulate native B- cells
b. short duration
c. high level of Ab
d. low affinity of Abs to Ags
12. they are cytokines that regulate the interaction
between lymphocyte and
other leukocyte:
a. interferon
b. Growth factor
c. Tumor necrosis factor
d. Interleukins
13. Tuberculin test is :
a. type I hypersensitivity
b. type II hypersensitivity
107
c. type III hypersensitivity
d. type VI hypersensitivity
b. IgA
109
c. Ig G
d. Ig D
27. Indirect anti-antibody test used to detect:
a. Sensitized RBCs in patient blood
b. IgG
c. IgM
d. Sensitized antibody in patient serum
28. Immunity is .
a. The science deal with study of bacteria.
b. The Body defense against any foreign body.
c. The science of viruses.
d. None of the above.
29. .means resistance or body defense
mechanism against any
microorganisms.
a. Immunitya.
b. Transplantation.
c. Opsonization.
d. Antigen.
30. Immunology is biological science that deal with
.................
a. Immunity
b. Immune system
c. a & b
d. Bacteriology
31. is the science of studying & detecting
serum antibodies .
a. Parasitology
b. Hematology
c. Serology
d. Pathology
110
32. functions of macrophages .
a. Cytokines secretions ; eg ( IL 2, IL4).
b. Activated immune cells.
c. Phagcocytosis.
d. All of above .
33. Opsonin is ..
a. Abs.
b. C3 .
c. a & b.
d. none of the above.
34. is the coating the foreign cell
by antibodies.
a. Adherence.
b. Opsonization.
c. Chemotaxis.
d. Endocytosis.
35. Which of the following is a step of phagocytosis
are
a. Chemotaxis.
b. Mutation.
c. Transplantation.
d. Hypersensitivity.
36. All of the following are Phagocytes
except
a. Monocyte
b. Neutrophil
c. Lymphocyte
d. Eosinophil.
37. Phagocytic cells are:
a. Mono-nuclear phagocytes
b. Poly-nuclear phagocytes
c. a and b
d. None of the above.
111
38. The nature of antigens may be:
a. Polypeptide
b. Lipoprotein
c. Glycoprotein
d. All of the above
39. Macrophage kills by release of:
a. sodium hydroxide
b. nitric oxide
c. hydrogen peroxide
d. none of the above
40. Microglial, mesanglial and synovial A cells are
a. Macrophages cell.
b. Neutrophils cell.
c. Eosinophils cell.
d. None of above
41. Antigen presenting cells include.
a. macrophages
b. NK cells
c. dendritic cells
d. all the above
42. Soluble (Humoral) factors include the following:
a. Lysosymes
b. Interferons
c. complements
d. All of the above
43. Liver macrophages known as..
a. Kupffer cell.
b. Synovial cell.
c. Microglial cell.
112
d. Mesanglial.
44. Brain macrophages known as
a. Kupffer cell
b. Synovial cell
c. Microglial cell
d. Mesanglial
45. T , B, and natural killer cells are.
a. Lymphocytes.
b. Erythrocytes.
c. Platelets.
d. Phagocytes.
46. Types of T lymphocytes..
a. T- effector.
b. T-suppressor.
c. T- Helper & T-cytotoxic.
d. All of the above.
47. Poly-nuclear phagocytes are..
a. Neutrophils.
b. Lymphocytes.
c. Monocytes.
d. Plasma cell.
48. The polynuclear cell included all the following
except
a. netrophil
b. eosinophil
c. lymphocyte
d. Basophil
49. The T lymphocyte population includes all the
following except
a. T- helper cell
b. T- cytotoxic cell
113
c. T- suppressor cell
d. NK cell
50. T- suppressor cells is responsible
for
a. Regulate the immune response.
b. Specific cytotoxicity of foreign cells.
c. Inhibition of immune response.
d. All of the above.
51. T cell devolope in
a. paye r's patches.
b. thymus gland.
c. bursa of fabricious.
d. none of the above.
52. They have ability to kill tumor:
a. Growth factor
b. kemokines
c. Tumer necrosis factor (TNF)
d. Mitogen
78. Phyto-heam-agglutinin is one of..
a. Mitogens.
b. Immunoglobulins.
118
c. Adjuants.
d. Haptens.
79. The nature of antigens may be:
a. Polypeptide
b. Lipoprotein
c. Glycoprotein
d. All of the above
80. Immunity via maternal is.
a. Natural passive
b. Artificial active
c. Natural active
d. Artificial passive
81. T- dependent antigens should be
a. Endogenous Ag.
b. Presented with MHC1.
c. Bind with CD8 on T cell.
d. Exogenous antigen.
82. Predominant Ig in primary (early) immune
response is ..
a. IgG
b. IgM
c. IgD
d. IgE
83. Immunoglobulin represents 75% of total serum
Igs of normal adult:
a. IgG .
b. IgM
c. IgD
d. IgE
84. The immunoglobulin with the largest molecular
weight is
a. IgG
119
b. IgM
c. IgE
d. IgD
85. The Ig that cannot fixes C is ..
a. IgG
b. IgA
c. IgE
d. IgD
86. The main Ig in secondary immune response is
..
a. Ig A
b. IgG
c. Ig D
d. IgM
87. ..is the most efficient Ig in complement
fixation.
a. IgM
b. Ig A
c. Ig G
d. IgD
88. IgA presented in..
a. saliva
b. tears
c. prostates
d. all the above
89. Which of the following Abs is predominant in
body secrestions?
a. IgD
b. IgA
c. IgM
d. non of the above
120
90. Which of the following Abs can cross the
Placenta?
a. IgA
b. IgG
c. IgM
d. Non of the above
91. .........................is pentameric Ig.
a. IgA
b. IgG
c. IgM
d. IgE
92. .... Binding with mast cells and
basophiles, so help in
degranulation and allergic reactions.
a. IgM
b. IgG
c. IgE
d. All of the above
93. Diameric Antibodies is
a. IgM
b. IgE
c. IgA
d. B &c
94. is present in highest
concentration in the blood of
human new born is
a. IgA
b. IgG
c. IgM
d. IgE
95. The immunoglobulin with the largest molecular
weight is
a. IgD.
b. IgE.
121
c. IgG.
d. IgM.
96. Half life of IgG antibody is
a. 6 days.
b. 8 days.
c. 21 days.
d. 10 days.
97. The major Ig expressed on B- cell surface
is.
a. IgD.
b. IgM.
c. IgE.
d. IgG.
98. Complement concentration increased in
a. nephritis
b. Serum sickness
c. Carcinoma
d. Malaria
99. Complement (C,) is a group of serum proteins
mainly
a. Globulin
b. Globulin
c. Globulin
d. Globulin
100. It is a chain of enzymatic reaction( Cascade)
a. cytokines
b. complement
c. lysozymes
d. none of the above
122
101. Presence of foreign cell surface is the starter
of complement activation
in ..
a. Classical pathway
b. Alternative pathway
c. Lectin pathway
d. All of the above
102. The function of complement is .
a. Cytolysis
b. Essential for phagocytosis
c. Essential for infectivity
d. A & b
103. Complement dependent serological tests are:
a. Complement fixation test
b. Cytotoxcity test
c. Opsonization test
d. All of the above
104. In classical pathway recognition stage means
..
a. Binding C1 to Ag- Ab
b. Activation stage
c. Formation of membrane attack complex
d. None of the above
105. Complement can enhance phagocytosis
because of the presence of receptors
for ..on macrophage.
a. CRP.
b. CDP.
c. C1.
d. C3b
106. Complement dependent serological tests
are.
a. Complement fixation test.
b. Glucose test.
123
c. Lipid profile tests.
d. All of the above.
107. The immune complex is the starter of
complement activation in.
a. Alternative pathway.
b. Lectin pathway.
c. Common pathway.
d. Classical pathway.
108. Recognition stage means..............................in
classical pathway of
complement activation.
a. Activation stage.
b. Binding C1 to Ag- Ab.
a. T helper cell
b. T cytotoxic cells
c. T effectors cells
d. None of the above
119. MHC-1 presents Ag to
a. CD+7
b. CD+8
c. CD+4
d. CD+9
120. Antigen presenting cells that activate T-helper
cells must express
which one of the following on their
surfaces..
a. Gamma interferon.
b. MHC class I.
c. MHC class II.
d. Ig E
121. In secondary immune response there is
a. Long duration
b. High level of Abs
c. Low Ag - Ab affinity
d. A and B are correct
122. Cell mediated immunity characterized by
b. alternative pathway
c. classical pathway
d. A&B
128
135. The major groups of fungal infection
are
a. Superficial mycosis
b. Visceral mycosis
c. Cutaneous mycosis
d. a & c
136. Treatment of tumors by radiological treatment
means .
a. Chemotherapy
b. Vaccination
c. Phagocytosis
d. Radiotherapy
137. Causes of mutation .
a. Carcinogenic substances
b. Oncogenic virus
c. Radiation
d. All of the above
138. Viruses associated with cancer
are.
a. Hepatitis B virus
b. Epstein Barr virus
c. Cytomegalovirus
d. All of the above
139. Alpha interferons are secreted from
.
a. T-lymphocytes.
b. B-lymphocytes.
c. Basophiles.
d. Viral infected cell.
140. Secreted from virus infected
cell.
a. C-reactive protein
b. complement
c. interferons
d. All of the above
129
141. In cancer mutation occurs in .
a. Proto-oncogene
b. Tumor suppressor gene
c. a and b
d. None of the above
142. .. It is malignant tumor in
epithelial cells
a. Carcinoma
b. Sarcoma
c. Leukemia
d. None of the above
143. . . means an expression of tumors in CT,
muscles and lymphoid
tissue.
a. Sarcoma.
b. Carcinoma.
c. Leukemia.
d. Hematoma.
144. If the tumor cells break off from its mass and
spread by blood or
lymph to certain site ,the tumor is:
a. Benign tumor.
b. Fibroid mass.
c. Malignant tumor.
d. All of the above.
145. Mutations may be due to
a. Carcinogenic substances.
b. Trauma.
c. Oncogenic virus.
d. a&c.
146. Treatment of tumors by radiological treatment
means
a. Psychotherapy.
b. Chemotherapy.
c. Radiotherapy.
130
d. all of the above.
147. .......................means abnormal and malignant
increase in leukocytes
number.
a. Sarcoma.
b. Carcinoma.
c. Leukemia.
d. All of the above.
148. CEA is..
a. Cytokines.
b. Tumor antigens
c. Lymphokines
d. All of the above
149. Immunopathology include
a. hypersensitivity
b. autoimmune disease
c. immunodeficiency
d. all the above
150. Hypersensitivity antigen called .
a. Immunogen
b. Pathogen
c. Allergen
d. None of the above
151. In Type I hypersensitivity IgE bind with
a. Mast cell
b. Monocyte
c. Lymphocyte
d. NK cell
152. Hypersensitivity type I mediated by.
a. Ig M
b. Ig G
131
c. Ig E
d. Ig A
a. type 1
b. type 11
c. type 111
d. type 1V
155. The effect of histamine in hypersensitivity
type II Involve
a. smooth muscle contraction
b. vasodilatation of blood vessels
c. increase vascular permeability
d. all the above
156. Rheumatoid arthritis is an example of
reactions
a. type I
b. type II
c. type III
d. type IV
157. Type ..hypersensitivity is
delayed type.
a. IV
b. III
c. II
d. VI
158. Allergens may be are
a. Insect bites.
132
b. Proteins & Food..
c. Drugs.
d. All of the above.
a. Occur in female
b. Occur in male
c. Occur in children
d. None of above
166. T- cell deficiency syndromes
include..
a. AIDS
b. Hepatitis
c. Wiskott- Aldrich Syndrome
d. Systemic Lupus Erythromatosus (SLE)
167. HIV infection cause acquired deficiency
in.
a. T-cytotoxic.
b. T-helper.
c. T-supressor.
d. All of the above
168. .means the process of taking cells
or tissue from one
individual and placing into other one.
a. Exocytosis.
b. Opsonizatoion.
c. Phagocytosis.
d. Transplantation.
169. Tissue transplantation depending
on..
a. ABO grouping
b. MHC compatibility
c. Tissue immunogenicity
d. Antibodies
134
170. Forms of grafting include..
a. Allograft.
b. Isograft.
c. Autograft.
d. All of the above.
171. occurs between animals of
different species, and
human|.
a. Allograft
b. Autograft
c. Isograft
d. Xenograft
172. ..occurs between genetically
different members of the
same species.
a. Allograft
b. Autograft
c. Isograft
d. Zenograft
173. Types of kidney rejections are:
a. Hyper acute rejection
b. Accelerated rejection
c. Acute rejection
d. All of the above
174. The medical uses of antibodies are
a. used in laboratory diagnosis of infection
b. used in tissue culture
c. used in laboratory diagnosis of cholesterol
d. None of the above
175. The immunoglobin that has smallest amount
in the serum is.
a. IgA.
b. Ig E.
135
c. Ig G.
d. IgD.
176. T-lymphocyte mature in .
a. thymus .
b. liver.
c. B.M.
d. lymph node.
177. Which Ig seen in condition of allergy and
parasite.
a. IgA.
b. Ig E.
c. Ig D.
d. IgG.
178. The normal CD4 count is:
a. 440 1600 microliter.
b. 4 16 microliter.
c. 44 - 160 microliter.
d. none of the above.
179. Antibodies produces by .,..
a. T-lymphocyte.
b. plasma cell.
c. RBCs.
d. neutrophils.
180. Antibodies means.
a. Is antigen.
b. It is carbohydrate substance.
c. It protein produce response to antigen.
d. All above.
136
ANSWER
1. B
2. C
3. A
4. B
5. B
6. A
7. A
8. C
9. C
10. D
11. C
12. D
13. D
14. C
15. D
16. D
17. B
18.
19.
20.
21.
22.
23.
24.
25.
26.
27.
28.
29.
30.
31.
32.
33.
34.
35.
36.
37.
38.
39.
40.
41.
42.
43.
44.
45.
46.
47.
48.
49.
50.
51.
52.
53.
54.
C
B
C
D
A
C
B
B
C
D
B
A
C
C
D
C
B
A
C
C
D
B
A
D
D
A
C
A
D
A
C
D
C
B
C
A
C
55. A
56. B
57. C
58. C
59. D
60. D
61. D
62. D
63. D
64. A
65. D
66. B
67. C
68. B
69. A
137
70. D
71. D
72. D
73. D
74. C
75. D
76. D
77. C
78. C
79. D
80. A
81. D
82. B
83. A
84. B
85. B
86. B
87. A
88. D
89. B
90. B
91. C
92. C
93. C
94. B
95. D
96. C
97. B
98. C
99. B
100. B
101. B
102. D
103. D
104. A
105. D
106. A
107. D
108. B
109. A
110. C
111. C
112. C
113. B
114. D
115. A
116. B
117. C
118. A
119. B
120. C
121. D
122. A
123. C
124. D
125. D
126. A
127. D
128.
129.
130.
131.
132.
133.
134.
135.
136.
137.
138.
139.
140.
141.
142.
143.
144.
145.
146.
147.
138
148.
149.
150.
151.
152.
153.
154.
155.
156.
157.
158.
159.
160.
161.
162.
163.
A
B
D
C
A
A
D
D
D
D
D
D
C
C
A
A
C
D
C
C
B
D
C
A
C
A
A
D
C
A
D
B
A
A
A
A
164.
165.
166.
167.
168.
169.
170.
171.
172.
173.
174.
175.
176.
177.
178.
179.
180.
B
A
A
B
D
B
D
D
A
D
A
B
A
B
A
B
C