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MCB 2000 Exam Three Study guide

1. How skin wards off infection. Name and describe two layers of skin
2. List important features of Staphylococci (S. aureus) and Streptococci (Strep pyogenes) including list
of virulence factors each one possesses/share, the disease each one causes/share
3. What makes Staph and Strep resist phagocytosis?
4. Name the antibiotic used to treat Staph skin infections (MRSA). Why resistance to this drug is an
5. List important characteristics/virulence factors and diseases caused by Streptococci genus.
6. Name and describe skin infections caused by viruses. Mode of transmission? Any treatment for
them? Is there any vaccine available for them? Name common childhood rashes caused by viruses
7. What is the difference between chickenpox and shingles? What is meant by recurring infection?
8. Define conjunctivitis. Which organism causes trachoma? What are the characteristics of this disease
9. What are the important features of herpes viruses? Compare HSV-1 and HSV-2? Which other viruses
belong to the family of herpes viruses?
10. What is meant by latent infection? Why is it hard to cure herpes? Name the drug use
11. What is the significance of Neonatal Conjunctivitis?
12. What meant by CNS. What is the function of meninges?
13. Name diseases associated with CNS. How active is the immune system in CNS?
14. Compare viral and bacterial meningitis? What causes meningococcal meningitis? What are the signs
and symptoms of meningitis?
15. Name several bacterial and viral diseases of nervous system
16. What are the important characteristics of rabies and polio infections?
17. What are the most important features of arboviruses?
18. Name the pneumonia caused by fungi?
19. What are prions? How do they cause diseases? Name diseases caused by prions.
20. Know everything about malaria
21. What are the important features of Lyme disease?
22. What are the signs and symptoms of septicemia? What is the significance of G- septicemia?
23. What are the important features of yeast infection? AIDS and yeast infection?
24. List the infections that affect AIDS patients more than others
25. Name causative agent and describe characteristics of plague
26. Define endocarditis, infectious mononucleosis
27. Important features of anthrax disease
28. How one must treat gangrene infection
29. What does DTP vaccine immunized for? How diphtheria damages tissue (location?)
30. What are different forms of anthrax? Why anthrax could be used as an agent of biological weapons?
31. Give examples of Hemorrhagic fevers
32. List important features and infections affecting respiratory tract
33. What causes TB? What are the important features of TB? What are the treatment options for TB?
34. Which organisms cause pneumonia? What are different types of pneumonia? Age groups?
35. What are the important characteristics of pneumococcal pneumonia? Alcoholism and Pneumonia?
36. What are the target cells for flu virus? What is the significance of the two surface proteins for flu
virus, for attachment of flu virus to the host tissue, for vaccine development?
37. Name drugs used to treat flu. What is their mechanism of action?
38. List important features of Common Cold Rhinoviruses, and Otitis media
39. What is meant by Healthcare Associated Pneumonia?
40. List two lung infections caused by fungi
41. Important features of Digestive tract?

42. What is meant by transmission via fecal-oral-route

43. What are the important features of Enterobacteriace. Give examples.
44. What is meant by food poisoning? Which bacteria cause food poisoning?
45. What are the important features of Streptococcus mutans (dental caries) and H. pylori (gastric ulcer?
46. Know everything about Hepatitis viruses
47. What are the important features of clostridium? Name diseases caused by these organisms
48. What type of infection is Cholera? What virulence factor is responsible for damage to the host?
49. Which bacteria cause Travelers diarrhea? Name the toxin produced by these bacteria?
50. What are the important features of diseases caused by Salmonella and Shigella?
51. What is CDAD? What diseases it causes? What type of virulence factors does it produces? What
kind of damages it causes? What is its relationship with use of antibiotics?
52. What are the important features of Giardia, Amoeba, and Cryptosporidia?
53. What are the characteristics of disease caused by rotaviruses
54. What are the significance of CMV,
55. List causative agents of Genital Ulcer diseases
56. Important features of HPV?
57. What disease is caused by Group B Streptococci?
58. What is meant by asymptomatic infection? Name two STDs that result in asymptomatic infection
59. Know everything about Neisseria and Chlamydia infections. Significance of PID?
60. Why did some mistake Chlamydia with viruses?
61. List important features of syphilis infection. Three stages, dormancy, birth defects?
62. What is meant by congenital disease? give some examples
63. Name the prime cause of life-threatening burn infection? Opportunistic pathogen
64. List name of diseases for which a form of vaccine is available.
65. List the arthropod-borne diseases
66. Define and give several examples of Zoonotic diseases
67. Define arthropod-borne disease. Give examples and indicate which insect is involved in each case
68. Define the following terms:
- Virulence factors:
o Endotoxins/exotoxins
o Capsules, Adhesions, pili, fimbriae
o Coagulase, hyaluronidase, hemolysins, leucocidins,
- Agent of Infectious diseases
- Examples of facultative intracellular and obligate intracellular pathogens
- Latent infections/dormant infection
- Acute/Chronic infection
- Nosocomial infection
- Coagulase
- Exotoxin/Endotoxin
- Hyaluronidase
- Alpha toxin/Streptolysin
- Leukocidine
- Cyst/Trophozoite
- Antigenic shift/Antigenic drift
- Septicemia/Toxemia
- Folliculitis, furuncle, carbuncle, Sty, Pimple
- Periodontal disease/Gingivitis
- Puerperal sepsis (fever)/Rheumatic fever/Scarlet fever/typhoid fever