1

CURRICULUMVITAE
Name:Dr.AubreyD.N.J.deGrey
Currentpost:ChiefScienceOfficer,SENSResearchFoundation
Researcharea:theroleandcausesofalltheaccumulatingandeventuallypathogenicmolecularand
cellular sideeffects of metabolism that constitute mammalian aging; the design of
interventionstoreverseand/orobviatethisaccumulation.
Bioparagraph(e.g.,ifyouhaveinvitedmetospeakandarecreatingpromotionalmaterial):
Dr. Aubreyde Grey is a biomedical gerontologist based in Cambridge, UK and Mountain View,
California,USA,andistheChiefScienceOfficerofSENSResearchFoundation,aCaliforniabased
501(c)(3) charity dedicated to combating the aging process. He is also EditorinChief of
RejuvenationResearch,theworldshighestimpactpeerreviewedjournalfocusedoninterventionin
aging.HereceivedhisBAandPh.D.fromtheUniversityofCambridgein1985and2000respectively.
Hisoriginalfieldwascomputerscience,andhedidresearchintheprivatesectorforsixyearsinthe
area of software verification before switching to biogerontology in the mid1990s. His research
interests encompass the characterisation of all the accumulating and eventually pathogenic
molecularandcellularsideeffectsofmetabolism(damage)thatconstitutemammalianagingandthe
design of interventions to repair and/or obviate that damage. He has developed a possibly
comprehensiveplanforsuchrepair,termedStrategiesforEngineeredNegligibleSenescence(SENS),
whichbreaksagingdownintosevenmajorclassesofdamageandidentifiesdetailedapproachesto
addressingeachone.AkeyaspectofSENSisthatitcanpotentiallyextendhealthylifespanwithout
limit,eventhoughtheserepairprocesseswillprobablyneverbeperfect,astherepaironlyneedsto
approachperfectionrapidlyenoughtokeeptheoveralllevelofdamagebelowpathogeniclevels.Dr.
deGreyhastermedthisrequiredrateofimprovementofrepairtherapieslongevityescapevelocity.
Dr.deGreyisaFellowofboththeGerontological SocietyofAmericaandtheAmericanAging
Association, and sits on the editorial and scientific advisory boards of numerous journals and
organisations.
Tel.:+441223366197or+16509386100
Email:aubrey@sens.org
Dateofbirth:20thApril,1963
Nationality:British
Maritalstatus:MarriedtoDr.AdelaideT.C.Carpenter;nochildren
Education:
B.A.(1985),M.A.(1988)andPh.D.(2000),UniversityofCambridge,Cambridge,UK
Pastemployment:
19851986:SinclairResearch,Cambridge,UK
19861992:ManMadeMinions,Cambridge,UK
1992(JanOct):EOComputer,Cambridge,UK
19922006:DepartmentofGenetics,UniversityofCambridge,Cambridge,UK

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20032009:ChairmanandChiefScienceOfficer,MethuselahFoundation
Honours:
2003:GerontologicalSocietyofAmerica:Fellow
2004:WorldTranshumanistAssociation:H.G.WellsAward
2005:AmericanAgingAssociation:Fellow
Societymemberships:
AmericanAgingAssociation(memberofboardofdirectors,20022007and2010present)
InternationalAssociationofBiomedicalGerontology(chair,20032005)
BritishSocietyforResearchonAgeing(memberofboardofdirectors,20032006)
GerontologicalSocietyofAmerica
InternationalCoenzymeQ10Association
MitochondrionResearchSociety
Scientificadvisoryboards(unpaid):
MaximumLifeFoundation
LegendaryPharmaceuticals
CentenarianSpeciesandRockfishProject
AlcorLifeExtensionFoundation
SingularityInstituteforArtificialIntelligence
ForesightInstitute
Biomind
LifeboatFoundation
Humanity+
CampaignforAgingResearch
Conferencesorganised:
Euromit4,Cambridge,UK,September1999(coorganiser)
StrategiesforEngineeredNegligibleSenescence,1stroundtable,Oakland,CA,USA,October2000
StrategiesforEngineeredNegligibleSenescence,2ndroundtable,LosAngeles,CA,USA,Aug.2001
StrategiesforEngineeredNegligibleSenescence,3rdroundtable,Cambridge,UK,December2002
InternationalAssociationofBiomedicalGerontology,10thCongress,Cambridge,UK,Sept.2003

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StrategiesforEngineeredNegligibleSenescence,4throundtable,Bethesda,MD,USA,July2004
StrategiesforEngineeredNegligibleSenescence,2ndconference,Cambridge,UK,September2005
StrategiesforEngineeredNegligibleSenescence,3rdconference,Cambridge,UK,September2007
UnderstandingAging:BiomedicalandBioengineringApproaches,LosAngeles,USA,June2008
StrategiesforEngineeredNegligibleSenescence,4thconference,Cambridge,UK,September2009
StrategiesforEngineeredNegligibleSenescence,5thconference,Cambridge,UK,September2011
StrategiesforEngineeredNegligibleSenescence,6thconference,Cambridge,UK,September2013
Journaleditorialboardmemberships:
RejuvenationResearch(editorinchief)
DisruptiveScienceandTechnology(executiveeditor)
Mitochondrion(associateeditor)
AGEJournaloftheAmericanAgingAssociation
CurrentStemCellResearch&Therapy
CurrentGerontologyandGeriatricsResearch
Publications:
Articlesinpeerreviewedjournals:
deGreyADNJ.Aproposedrefinementofthemitochondrialfreeradicaltheoryofaging.BioEssays
1997;19(2):161166.
deGreyADNJ.Amechanismproposedtoexplaintheriseinoxidativestressduringaging.JAnti
AgingMed1998;1(1):5366.
deGreyADNJ.Incorporationoftransmembranehydroxidetransportintothechemiosmotictheory.
BioelectrochemBioenerg1999;49(12):4350.
deGreyADNJ.Thenoncorrelationbetweenmaximumlongevityandenzymaticantioxidantlevels
among homeotherms; implications for retarding human aging. J AntiAging Med 2000;
3(1):2536.
de Grey ADNJ. The reductive hotspot hypothesis: an update. Arch Biochem Biophys 2000;
373(1):295301.
de Grey ADNJ. Mitochondrial gene therapy: an arena for the biomedical use of inteins. Trends
Biotechnol2000;18(9):394399.
deGreyADNJ.Aproposedmechanismfortheloweringofmitochondrialelectronleakbycaloric
restriction.Mitochondrion2001;1(2):129139.
deGreyADNJ.UKresearchonthebiologyofaging.ExpGerontol2001;37(1):17.

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deGreyADNJ,AmesBN,AndersenJK,BartkeA,CampisiJ,HewardCB,McCarterRJM,StockG.
TimetotalkSENS:critiquingtheimmutabilityofhumanaging.AnnalsNYAcadSci2002;
959:452462.
de Grey ADNJ. The reductive hotspot hypothesis of mammalian aging: membrane metabolism
magnifiesmutantmitochondrialmischief.EurJBiochem2002;269(8):20032009.
deGreyADNJ.HO2:theforgottenradical.DNACellBiol2002;21(4):251257.
deGreyADNJ,BaynesJW,BerdD,HewardCB,PawelecG,StockG.Ishumanagingstillmysterious
enoughtobeleftonlytoscientists?BioEssays2002;24(7):667676.
deGreyADNJ.Bioremediationmeetsbiomedicine:therapeutictranslationofmicrobialcatabolismto
thelysosome.TrendsBiotechnol2002;20(11):452455.
deGreyADNJ.Anengineersapproachtothedevelopmentofrealantiagingmedicine.Sciences
SAGEKE2003;2003(1):vp1.
deGreyADNJ.Challengingbutessentialtargetsforgenuineantiageingdrugs.ExpertOpinTherap
Targets2003;7(1):15.
deGreyADNJ.Critiqueofthedemographicevidenceforlatelifenonsenescence.BiochemSoc
Trans2003;31(2):452454.
deGreyADNJ.UKresearchonthebiologyofagingthenexttenyears.Lifespan2003;11(1):14.
deGreyADNJ.Ahypothesisfortheminimaloverallstructureofthemammalianplasmamembrane
redoxsystem.Protoplasma2003;221(12):39.
deGreyADNJ.Theforeseeabilityofrealantiagingmedicine:focusingthedebate.ExpGerontol
2003;38(9):927934.
deGreyADNJ.Falsifyingfalsifications:themostcriticaltaskoftheoreticiansinbiology.MedHypoth
2004;62(6):10121020.
deGreyADNJ.Escapevelocity: whytheprospectofextreme humanlifeextensionmatters now.
PLoSBiol2004;2(6):723726.
deGreyADNJ,CampbellFC,DokalI,FairbairnLJ,GrahamGJ,JahodaCAB,PorterACG.Total
deletionofinvivotelomereelongationcapacity:anambitiousbutpossiblyultimatecureforall
agerelatedhumancancers.AnnalsNYAcadSci2004;1019:147170.
deGreyADNJ.Biogerontologistsdutytodiscusstimescalespublicly.AnnalsNYAcadSci2004;
1019:542545.
deGreyADNJ.Interspeciestherapeuticcloning:theloomingproblemofmitochondrialDNAandtwo
possiblesolutions.RejuvenationRes2004;7(2):9598.
deGreyADNJ.Theunfortunateinfluenceoftheweatherontherateofaging:whyhumancaloric
restrictionoritsemulationmayonlyextendlifeexpectancyby23years.Gerontology2005;
51(2):7382.
deGreyADNJ.Forcesmaintainingorganellargenomes:isanyasstrongasgeneticcodedisparityor
hydrophobicity?BioEssays2005;27(4):436446.

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de Grey ADNJ. Wholebody interdiction of lengthening of telomeres: a proposal for cancer
prevention.FrontBiosci2005;10:24202429.
deGreyADNJ.Reactiveoxygenspeciesproductioninthemitochondrialmatrix:implicationsforthe
mechanismofmitochondrialmutationaccumulation.RejuvenationRes2005;8(1):1317.
deGreyADNJ.Resistancetodebateonhowtopostponeageingisdelayingprogressandcostinglives.
EMBORep2005;6(S1):S49S53.
deGreyADNJ,AlvarezPJJ,BradyRO,CuervoAM,JeromeWG,McCartyPL,NixonRA,Rittmann
BE,SparrowJR.Medicalbioremediation:prospectsfortheapplicationofmicrobialcatabolic
diversitytoagingandseveralmajoragerelateddiseases.AgeingResRev2005;4(3):315338.
deGreyADNJ.Lifeextension,humanrights,andtherationalrefinementofrepugnance.JMedEthics
2005;31(11):659663.
de Grey ADNJ. A strategy for postponing aging indefinitely. Stud Health Technol Inform 2005;
118:209219.
deGreyADNJ.Theplasmamembraneredoxsystem:acandidatesourceofagingrelatedoxidative
stress.AGEJAmAgingAssoc2005;27(2):129138.
de Grey ADNJ. Appropriating microbial catabolism: a proposal to treat and prevent
neurodegeneration.NeurobiolAging2006;27(4):589595.
deGreyADNJ.ExtrapolaholicsAnonymous:whydemographersrejectionsofahugeriseincohort
lifeexpectancyinthiscenturyareoverconfident.AnnalsNYAcadSci2006;1067:8393.
deGreyADNJ.Foreseeable pharmaceutical repairofagerelated extracellular damage. CurrDrug
Targets2006;7(11):14691477.
deGreyADNJ.Freeradicalsinaging:causalcomplexityanditsbiomedicalimplications.FreeRadic
Res2006;40(12):12441249.
deGreyADNJ.Theurgencydilemma:islifeextensionresearchatemptationoratest?Update2006;
21(1):610.
deGreyADNJ.Thenaturalbiogerontologyportfolio:defeatingagingasamultistageultraGrand
Challenge.AnnalsNYAcadSci2007;1100:409423.
de Grey ADNJ. Protagonistic pleiotropy: why cancer may be the only pathogenic effect of
accumulatingnuclearmutationsandepimutationsinaging.MechAgeingDev2007;128(7
8):456459.
PhoenixCR,deGreyADNJ.Amodelofagingasaccumulateddamagematchesobservedmortality
patterns and predicts the lifeextending effects of prospective interventions. AGE 2007;
29(4):133189.
de Grey ADNJ. Calorie restriction, postreproductive lifespan and programmed aging: a plea for
rigour.AnnalsNYAcadSci2007;1119:296305.
deGreyADNJ.Alzheimers,atherosclerosis,andaggregates:Aroleforbacterialdegradation.Nutr
Rev2007;65(12Pt.2):S221S227.
deGreyADNJ.Lifespanextensionresearchandpublicdebate:societalconsiderations.Studiesin
Ethics,LawandTechnology2007;1(1):5.

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deGreyADNJ.Ourrighttolife.JEvolTechnol2008;17(2):5357.
de Grey ADNJ. The singularity and the Methuselarity: similarities and differences. Stud Health
TechnolInform2009;149:195202.
deGreyADNJ.Makingsurethathealthandwealthkeeppacewithextendedlifeexpectancy.United
Academics Magazine 2012; 2012(April/May): http://www.united
academics.org/magazine/17748/makingsurethathealthandwealthkeeppacewithextended
lifeexpectancy/
de Grey ADNJ. Zenos paradox and the faith that technological gamechangers are impossible.
Gerontology2012,inpress.
Zealley BJ,deGreyADNJ.Strategies forengineered negligible senescence (SENS).Gerontology
2012,inpress.
Reviewsandcommentaries:
de Grey ADNJ. More on mitochondria and senescence: Response to Gershon. BioEssays 1997;
19(6):534534.
deGreyADNJ.ReviewofCadenasEandPackerL(eds),UnderstandingtheProcessofAging:The
RolesofMitochondria,FreeRadicals,andAntioxidants.JAntiAgingMed1999;2(3):291.
deGreyADNJ.ReviewofHarmanD,HollidayRandMeydaniM(eds),TowardsProlongationofthe
HealthyLifeSpan:PracticalApproachestoIntervention.JAntiAgingMed1999;2(3):292.
deGreyADNJ.Populargerontologycomesofage.ReviewofKirkwoodTBL,TimeofourLives.
BioEssays1999;21(9):802803.
deGreyADNJ.BiologistsabandonPopperattheirperil.BioEssays2000;22(2):206207.
de Grey ADNJ. The function of mitochondrial dysfunction in aging. J AntiAging Med 2000;
3(1):109112.
deGreyADNJ.ReviewofAsardH,BercziAandCaubergsRJ(eds),PlasmaMembraneRedox
Systems and Their Role in Biological Stress and Disease. Antioxid Redox Signal 2000;
2(2):371372.
deGreyADNJ.Redox2000:the5thinternationalconferenceonplasmamembraneredoxsystemsand
theirroleinbiologicalstressanddisease.AntioxidRedoxSignal2000;2(2):373374.
deGreyADNJ.ReviewofSchefflerI,Mitochondria.JAmAgingAssoc2000;23(4):255.
deGreyADNJ.Antioxidantsandredoxsignaling:Internetresources.AntioxidRedoxSignal2000;
2(4):937940.
deGreyADNJ.Gerontologistsandthemedia:thedangersofoverpessimism.Biogerontology2000;
1(4):369370.
deGreyADNJ.ReviewofWickensA,TheCausesofAging.ExpGerontol2000;34(8):10171018.
deGreyADNJ.Responsetotelomereshorteningwithaginginhumanliver.JGerontolABiolSci
MedSci2001;56(6):B237B238.

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deGreyADNJ.Responsetoapproachesandlimitationstogenetherapyformitochondrialdiseases,
Antioxid.RedoxSignal.2001;3:451460.AntioxidRedoxSignal2001;3(6):11531155.
deGreyADNJ.ReviewofFinchCEandKirkwoodTBL,Chance,development,andaging.Exp
Gerontol2001;36(10):17831785.
deGreyADNJ.NatureoftheagingprocessOpendiscussion.AnnalsNYAcadSci2002;959:463
465.
deGreyADNJ,GavrilovL,OlshanskySJ,ColesLS,CutlerRG,FosselM,HarmanSM.Antiaging
technologyandpseudoscience.Science2002;296(5568):656.
deGreyADNJ.Threedetailedhypothesesimplicatingoxidativedamagetomitochondriaasamajor
drivingforceinhomeothermaging.EurJBiochem2002;269(8):1995.
deGreyADNJ.ReviewofNichollsDGandFergusonSJ,Bioenergetics3.Mitochondrion2002;
2(3):211213.
de Grey ADNJ. Fear of misrepresentation cannot justify silence about foreseeable lifeextension
biotechnology.BioEssays2003;25(1):9495.
de Grey ADNJ. Overzealous maximumlikelihood fitting falsely convicts the slope heterogeneity
hypothesis.ExpGerontol2003;38(8):921923.
deGreyADNJ.ReviewofMattsonMPandVanZantG(eds),StemCells:ACellularFountainof
Youth.ExpGerontol2003;38(9):10251026.
de Grey ADNJ. Breathtaking biomedical blind spots. Review of Guarente L, Ageless Quest.
BioEssays2004;26(1):108109.
deGreyADNJ.Modelsontrial:falsifyingoverstatedclaimsofgeneralitydoesnotfalsifycorrectly
statedones.ExpGerontol2004;39(3):453.
deGreyADNJ.Mitochondriainhomeothermaging:willdetailedmechanisms consistentwiththe
evidencenowreceiveattention?AgingCell2004;3(2):77.
deGreyADNJ.Reportofopendiscussiononthefutureoflifeextensionresearch.AnnalsNYAcad
Sci2004;1019:552553.
deGreyADNJ.WelcometoRejuvenationResearch.RejuvenationRes2004;7(1):12.
deGreyADNJ.LeonKass:quitesubstantiallyright.RejuvenationRes2004;7(2):8991.
deGreyADNJ.Threeselfevidentlifeextensiontruths.RejuvenationRes2004;7(3):165167.
deGreyADNJ.Mitochondrialmutationsinmammalianaging:anoverhastyaboutturn?Rejuvenation
Res2004;7(3):171174.
deGreyADNJ. Meetingreport:Regenerate2004:tissueengineeringthehumanbody,June1012,
2004,Seattle.RejuvenationRes2004;7(3):226228.
deGreyADNJ.Aging,childlessness,oroverpopulation:thefuturesrighttochoose.RejuvenationRes
2004;7(4):237238.
deGreyADNJ. Meetingreport:8th InternationalSymposiumontheMaillardReaction.Charleston,
SouthCarolina,August28September12004.RejuvenationRes2004;7(4):257260.

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deGreyADNJ.Whenandwheretopublishimportantfindings:acasualtyofbiogerontologysriseto
respectability.RejuvenationRes2005;8(1):12.
deGreyADNJ.Therateofaging:acounterproductivelyundefinableterm.RejuvenationRes2005;
8(2):7778.
deGreyADNJ.Theethicalstatusofeffortstopostponeaging:areplytoHurlbut.RejuvenationRes
2005;8(3):129130.
deGreyADNJ.TheSENSChallenge:$20,000saystheforeseeabledefeatofagingisnotlaughable.
RejuvenationRes2005;8(4):207210.
deGreyADNJ.Meetingreport:InternationalAssociationofBiomedicalGerontology,11thCongress,
13th16thAugust,2005,Aarhus,Denmark.RejuvenationRes2005;8(4):264266.
deGreyADNJ.Likeitornot,lifeextensionresearchextendsbeyondbiogerontology.EMBOReports
2005;6(11):1000.
deGreyADNJ.Compressionofmorbidity:thehypeandthereality,part1.RejuvenationRes2006;
9(1):12.
deGreyADNJ.Compressionofmorbidity:thehypeandthereality,part2.RejuvenationRes2006;
9(2):167168.
deGreyADNJ.HasHippocrateshadhisday?RejuvenationRes2006;9(3):371373.
de Grey ADNJ. SENS survives the Challenge; now lets get to work. Rejuvenation Res 2006;
9(4):429430.
deGreyADNJ.IsSENSafarrago?RejuvenationRes2006;9(4):436439.
deGreyADNJ.SENSishard,yes,butnottoohardtotry:areplytoWarner.RejuvenationRes2006;
9(4):443445.
deGreyADNJ.AgingandairborneHIV:areassuringanalogy.RejuvenationRes2007;10(1):13.
deGreyADNJ.Newdevelopments at Rejuvenation Research:highimpact factor, advance online
publicationandmore.RejuvenationRes2007;10(2):125126.
de Grey ADNJ. The case for prioritising research on lateonset lifeextension interventions in
mammals.RejuvenationRes2007;10(3):257259.
deGreyADNJ.Edmonton:afuturecenterforpioneeringbiomedicalgerontology?RejuvenationRes
2007;10(3):345347.
deGreyADNJ.Theneedtodebalkanizegerontology:acasestudy.RejuvenationRes2007;10(4):431
434.
de Grey ADNJ. Understanding and tackling aging: two fields communicating (a little) at last.
RejuvenationRes2007;10(4):637640.
deGreyADNJ.Oldpeoplearepeopletoo:whyitisourdutytofightagingtothedeath.CatoUnbound
2007(12):leadessay.
deGreyADNJ.Curiosityisaddictive,andthisisnotnecessarilyagoodthing.RejuvenationRes2008;
11(1):13.

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de Grey ADNJ. Man, machines, manufacturing and maintenance: merits of a muchmaligned
metaphor.RejuvenationRes2008;11(2):277279.
deGreyADNJ.Longlivetheunreasonableman.RejuvenationRes2008;11(3):541542.
deGreyADNJ.CombatingtheTithonusError:whatworks?RejuvenationRes2008;11(4):713715.
deGreyADNJ. Transsimianismandtruthiness:hintsofprogressinthedebateonwhetheragingis
good.RejuvenationRes2008;11(5):857859.
deGreyADNJ.Estimatingratesoffuturebiomedicalprogress:areplytoBains.BiosciHyp2008;
1(5):286.
deGreyADNJ.Aging:aforeseeabletargetofstemcellsandregenerativemedicine.WorldStemCell
Report2008:1719.
deGreyADNJ.Cautionarytalesoftheunexpected.RejuvenationRes2008;11(6):989990.
deGreyADNJ.Consolidatingthemissiontodefeataging:abigstepforward.RejuvenationRes2008;
11(6):10611063.
deGreyADNJ.Cracksinsocialgerontologysproagingedifice.RejuvenationRes2009;12(1):13.
de Grey ADNJ. The curiously misunderstood role of evidence in designing new technology.
RejuvenationRes2009;12(2):7576.
deGreyADNJ. Whyaresomanypeoplesounashamedlyselfishabouttheprospectofcombating
aging?RejuvenationRes2009;12(3):165167.
deGreyADNJ.HowismutantmitochondrialDNAclonallyamplified?Muchnewevidence,stillno
answers.RejuvenationRes2009;12(3):217219.
de Grey ADNJ. Persons of tenure: less fortunate than they may seem. Rejuvenation Res 2009;
12(4):237238.
de Grey ADNJ. Aging: can piecemeal preventative maintenance work? World Stem Cell Report
2009:101103.
deGreyADNJ.TheEinsteinianimperative.RejuvenationRes2009;12(6):383385.
deGreyADNJ. Hypeandantihypeinacademicbiogerontologyresearch. RejuvenationRes2010;
13(23):137138.
RaeMJ,ButlerRN,CampisiJ,deGreyADNJ,FinchCE,GoughM,MartinGM,VijgJ,PerrottKM,
LoganBJ.Thedemographicandbiomedicalcaseforlatelifeinterventionsinaging.SciTransl
Med2010;2(40):40cm21.
de Grey ADNJ. Reaping the longevity dividend in time: biogerontology heavyweights advocate
seekinglateonsetinterventionsagainstaging.RejuvenationRes2010;13(4):383385.
deGreyADNJ.Biology:afieldinneedofacommunityculture.RejuvenationRes2010;13(5):507
508.
deGreyADNJ.EuropeanCouncilofArt:anewinitiativetocombinebothfieldsandculturesinthe
pursuitofvisionarygoals.RejuvenationRes2010;13(6):629630.
deGreyADNJ.Prematuredeathsclosetohome.RejuvenationRes2011;14(1):12.

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deGreyADNJ.Silverliningsofoversimplification.RejuvenationRes2011;14(2):109110.
deGreyADNJ.Theevolutionofdogma.RejuvenationRes2011;14(3):239240.
deGreyADNJ.Progress...butspeedisoftheessence.RejuvenationRes2011;14(4):351352.
deGreyADNJ.Whenindoubt,maximizeyouroptions.RejuvenationRes2011;14(5):467468.
deGreyADNJ.Themanylevelvalueofproofsofconcept.RejuvenationRes2012;15(2):121122.
ZealleyBJ,deGreyADNJ.Cancerscooptcohabitants'catabolism:Autophagyandsenescenceinthe
tumorstroma.CellCycle2012;11(12):2230.
de Grey ADNJ. Biological versus medical limits on aging: a distinction we must not elide.
RejuvenationRes2012;15(3):255256.
deGreyADNJ.What'sreallydelayingthedefeatofaging?RejuvenationRes2012;15(4):347348.
de GreyADNJ. The future dominance ofcombination therapies: implications for today's medical
research.RejuvenationRes2012;15(5):443444.
deGreyADNJ.Dilemmasofdiscussingdramaticdevelopments.RejuvenationRes2012;15(6):543
544.
Books:
deGreyADNJ.Themitochondrialfreeradicaltheoryofaging.Austin,TX:LandesBioscience,1999,
212pp,hardcover(ISBN157059564X).
deGreyADNJ,RaeM.EndingAging:Therejuvenationbiotechnologiesthatcouldreversehuman
aginginourlifetime.NewYork,NY:St.MartinsPress,2007,416pp,hardcover(ISBN0312
367066).Paperbackedition:St.MartinsPress,2008,448pp(ISBN0312367074).
Bookchapters:
deGreyADNJ.Arethose13proteinsreallyunimportable?In:FromSymbiosistoEukaryotism
EndocytobiologyVII(E.Wagneretal.,eds.),GenevaUniversityPress,1999,pp.489502.
deGreyADNJ.Mitochondrialmutationsinvertebrateaging.In:Oxidativestressandaging:advances
inbasicscience,diagnostics,andintervention(R.G.CutlerandH.Rodriguez,eds.),World
ScientificPublishing,2002,pp.437451.
deGreyADNJ.MechanismsunderlyingtheagerelatedaccumulationofmutantmitochondrialDNA.
In:Geneticsofmitochondrialdiseases(I.J.Holt,ed.),OxfordUniversityPress,2003,pp.247
275.
de Grey ADNJ. An engineers approach to the development of real antiaging medicine. In: The
FountainofYouth:Ethical,Religious,andExistentialPerspectivesonaBiomedicalGoal(S.G.
PostandR.H.Binstock,eds.),OxfordUniversityPress,2004,pp.249267.
deGreyADNJ.Thewaronaging.In:TheScientificConquestofDeath(B.J.Kleinetal.,eds.),Libros
enRed,2004,pp.1729.

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de GreyADNJ. Foreseeable and more distant rejuvenation therapies. In: Aging Interventions and
Therapies(S.I.S.Rattan,ed.),WorldScientific,2005,pp.379395.
deGreyADNJ.Theforeseeabilityofrealantiagingmedicine.In:AntiAgingMedicalTherapeutics,
volume7(R.Klatz,ed.),AmericanAcademyforAntiAgingMedicine,2005,pp.5968.
deGreyADNJ.Lysosomalenhancementwithmicrobialhydrolases:anovelstrategyforremoving
proteinaggregates.In: NewTrendsinAlzheimerandParkinsonDisorders:ADPD2005 (A.
Fisheretal.,eds.),Medimond,2005,pp.5154.
deGreyADNJ.Genetherapy.In:EncyclopediaofAging,4 thEdition(R.Schulzetal.,eds.),Springer,
2006,pp.439443.
deGreyADNJ.Strategieperuninvecchiamentotranscurabileingegnerizzato.In:Alterandoildestino
dellumanit(P.Donghi,ed.),Proceedingsofthe2005Spoletoscienzaconference,Laterza&
Figli,2006,pp.4963.
deGreyADNJ.Defeatofagingutopiaorforeseeablescientificreality?In:TheFutureofLifeand
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de Grey ADNJ. Rejuvenating neurons and glia with microbial enzymes. In: Interaction Between
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Invitationstospeak:
Seminars:
UniversityofIndiana,Bloomington,IN,USA,April1997
UniversityofCalifornia,Riverside,CA,USA,February1998
UniversityofNewcastle,UK,October1998
UniversityofLinkping,Sweden,May1999
UniversityofMarburg,Germany,July1999
ETH(EidgenssischeTechnischeHochschule),Zurich,Switzerland,September1999
MRCLaboratoryofMolecularBiology,Cambridge,UK,November1999
MRCDunnHumanNutritionUnit,Cambridge,UK,January2000
UniversityofWashington,Seattle,WA,USA,June2000
UniversityofCalifornia,Irvine,CA,USA,October2000
UniversityofCalifornia,LosAngeles,CA,USA,October2000
UniversityofSouthernCalifornia,LosAngeles,CA,USA,October2000
KronosLongevityResearchInstitute,Phoenix,AZ,USA,February2002
UniversityofSouthampton,UK,April2002
GrayCancerInstitute,Northwood,UK,September2002
UniversityofNewcastle,UK,February2003
UniversityofCalifornia,SantaBarbara,CA,USA,March2003
UnileverResearchandDevelopment,Colworth,UK,April2004
UniversityofTampere,Finland,May2004
ExtroBritannia,Wolverton,UK,July2004
CCLRCDaresburyLaboratory,Warrington,UK,October2004
UniversityofBirmingham,UK,November2004
UniversityofCalgary,Calgary,AB,Canada,February2005
UniversityofAlberta,Edmonton,AB,Canada,February2005
BaylorCollegeofMedicine,Houston,TX,USA,March2005
RiceUniversity,Houston,TX,USA,March2005
UniversityofTexasHealthSciencesCenter,SanAntonio,TX,USA,March2005
CafScientifique,Edinburgh,UK,April2005

13
HunterCollege,NewYork,NY,USA,April2005
StanfordUniversity,Stanford,CA,USA,June2005(twotalks)
UniversityofUtrecht,Utrecht,TheNetherlands,September2005
LondonRegenerativeMedicineNetwork,UniversityCollege,London,UK,October2005
UniversityofCambridgeInstituteofBiotechnology,Cambridge,UK,December2005
KronosLongevityResearchInstitute,Phoenix,AZ,USA,December2005
PeopleUnlimited,Scottsdale,AZ,USA,December2005
LomaLindaUniversity,LomaLinda,CA,USA,February2006
Faith,ReasonandCommunityForum,LomaLinda,CA,USA,February2006
KnutsfordSciBAr,Knutsford,UK,February2006
Demos,London,UK,February2006
SierraSciences,Reno,NV,USA,February2006
CorvenCorporateFinance,London,UK,March2006
UniversityofCambridgeMedicalSociety,Cambridge,UK,March2006
UniversityofArizona,Tucson,AZ,USA,April2006
ArizonaStateUniversityBiodesignInstitute,Tempe,AZ,USA,April2006
YaleUniversity,NewHaven,CT,USA,May2006
Junto,NewYork,NY,USA,June2006
BUPA,London,UK,September2006
UniversityofMichigan,AnnArbor,MI,USA,October2006
ExtroBritannia,London,UK,October2006
ThePensionsNetWork,Maidstone,UK,December2006
UniversityofHeidelberg,Heidelberg,Germany,January2007
CambridgeUniversityStudentPugwashSociety,Cambridge,UK,February2007
BuckInstituteforAgeResearch,Novato,CA,USA,March2007
UniversityofHohenheim,Stuttgart,Germany,April2007
Google,MountainView,CA,USA,May2007
RoyalSocietyofArts,London,UK,June2007
Google,MountainView,CA,USA,June2007
SanFranciscoFutureSalon,PaloAlto,CA,USA,July2007
CambridgeHitechAssociationofSmallEnterprises,Cambridge,UK,August2007
BritishHumanistAssociation,London,UK,August2007
UniversityofCaliforniaBerkeley,Berkeley,CA,USA,October2007

14
OxfordUniversityScienceSociety,Oxford,UK,October2007
SangamoSciences,Richmond,CA,USA,October2007
MilnerSociety(QueensCollegeCambridge),Cambridge,UK,November2007
CaseWesternReserveUniversity,Cleveland,OH,USA,November2007(twotalks)
RoyalCollegeofArts,London,UK,November2007
Google,MountainView,CA,USA,December2007
BangorSciBAr,Bangor,UK,January2008
DanaCentre,London,UK,January2008
TrinityCollegeScienceSociety,Cambridge,UK,January2008
UniversityofPennsylvania,Philadelphia,PA,February2008
NewYorkUniversity,NewYork,NY,USA,February2008
CassBusinessSchool,London,UK,February2008
CambridgeYoungSolicitorsandProfessionalsGroup,Cambridge,UK,February2008
StPaulsSchool,London,UK,March2008
SpiritoftheSenses,Phoenix,AZ,USA,March2008
UniversityofWisconsin,Madison,WI,USA,April2008
OrlandoScienceCenter,Orlando,FL,USA,May2008
Proctor&GambleworkshopFuturethinking,NewYork,NY,USA,June2008
UniversityofAlberta,Edmonton,Canada,June2008
ThePensionsNetWork,Hurley,UK,June2008
TorontoPublicLibraryNetwork,Toronto,Canada,June2008
ExtroBritannia,London,UK,July2008
UniversityofHull,Hull,UK,July2008
CafScientifique,Lichfield,UK,July2008
TheMotleyFool,Alexandria,MD,USA,July2008
Google,NewYork,NY,USA,July2008
UCLAstudentgroupPOLIS,LosAngeles,CA,USA,August2008
NuSkin,Provo,UT,USA,August2008
NASAAmesResearchCenter,MountainView,CA,UA,August2008
ThinkTankderBankSarasin&Cie,Zurich,Switzerland,September2008
KronosLongevityResearchInstitute,Scottsdale,AZ,USA,September2008
UniversityofGhent,Ghent,Belgium,October2008
JewishCommunityCenterofSanFrancisco,SanFrancisco,CA,USA,October2008

15
StanfordTranshumanistAssociation,PaloAlto,CA,USA,October2008
TheNatureDebate,London,UK,November2008
SpiritoftheSenses,Phoenix,AZ,USA,December2008
HEALES,Narbonne,France,January2009
CaixaFoundation,Lleida,Spain,January2009
CaixaFoundation,Barcelona,Spain,January2009
CaixaFoundation,Madrid,Spain,January2009
UniversityofPalma,Palma,Mallorca,January2009
CaixaFoundation,Tarragona,Spain,January2009
KentStateUniversity,Kent,OH,USA,February2009
UniversityofManchester,Manchester,UK,February2009
UniversityofLiverpool,Liverpool,UK,February2009
MoscowStateUniversity,Moscow,Russia,March2009
UniversityofWestminster,London,UK,March2009
UniversityofGhent,Ghent,Belgium,March2009
BankSarasin&Cie,Interlaken,Switzerland,April2009
QueenMaryUniversityofLondon,London,UK,April2009
SmartLifeForum,PaloAlto,CA,USA,May2009
CommonwealthClub,SanFrancisco,CA,USA,May2009
UniversityofLeicester,Leicester,UK,June2009
SingularityUniversity,MountainView,CA,USA,July2009
SummerScienceProgram,Ojai,CA,USA,July2009
SkepticsinthePub,London,UK,August2009
KingsFund,London,UK,September2009
NewYorkAcademyofSciences,NewYork,NY,USA,September2009
SiliconValleyTranshumanistMeetup,PaloAlto,CA,USA,September2009
TheCommonwealthMedicalCollege,Scranton,PA,USA,September2009
UKTranshumanistAssociation,London,UK,October2009
OxfordUniversityScienceSociety,Oxford,UK,October2009
KarolinskaInstitute,Stockholm,Sweden,October2009(twotalks)
OsherLifelongLearningInstitute,Saginaw,MI,USA,November2009
NHSWorkforceReviewTeam,Winchester,UK,December2009
HaberdashersAskesBoysSchool,Elstree,UK,January2010

16
WellcomeTrust,London,UK,January2010
StaffordshireUniversity,Stafford,UK,March2010
OmegaInstitute,Rhinebeck,NY,USA,October2010
Nationalandinternationalmeetings:
EndocytobiologyVII,Freiburg,Germany,April1998
4thEuropeanCongressofGerontology,Berlin,Germany,July1999
Euromit4,Cambridge,UK,September1999
Symposium:stressandageinginanimalsandmicroorganisms,Porto,Portugal,June2000
BBSRCScienceofAgeingsymposium,Manchester,UK,January2001
O2SA(OxidativeStressinAging),2ndConference,Maui,HI,USA,April2001
InternationalAssociationofBiomedicalGerontology,9thCongress,Vancouver,Canada,June2001
27thMeetingofFEBS,Lisbon,Portugal,July2001
WarburgSociety,inauguralconference,PointClear,LA,USA,October2001
6thInternationalConferenceonPlasmaMembraneRedoxSystems,Ravenna,Italy,March2002
MechanismsofCaloricRestrictionconference,Bandera,TX,USA,October2002
3rdEuropeanCongressofBiogerontologypremeeting,SanMiniato,Italy,November2002
5thAlcorConferenceonExtremeLifeExtension,NewportBeach,CA,USA,November2002
ForesightInstitute2003SeniorAssociatesGathering,PaloAlto,CA,USA,May2003
Transvision2003,YaleUniversity,NewHaven,CT,USA,June2003
CMIBsymposiumProjectingFutureMortality,Edinburgh,UK,October2003
Pop!Tech2003conferenceSeaChange,Camden,ME,USA,October2003
7thInternationalConferenceonPlasmaMembraneRedoxSystems,Asilomar,CA,USA,April2004
PittsburghsymposiumFrontiersinHumanEmbryonicStemCells,Pittsburgh,PA,USA,May2004
3rdMedicalandAestheticProceduresMeeting,Barcelona,Spain,June2004
3rdAsiaPacificConferenceandExhibitiononAntiAgeingMedicine,Singapore,June2004
Transvision2004,Toronto,Canada,August2004
1stAntiAgeingConferenceLondon,London,UK,September2004
GermanSocietyofGerontologyandGeriatrics,7thCongress,Hamburg,Germany,October2004
5thNeurobiologyofAgingsymposium,SanDiego,CA,USA,October2004
IntegrativeMedicalTherapeuticsforAntiAgingconference,LasVegas,NV,USA,October2004
EMBL/EMBOconferenceonScienceandSociety,Heidelberg,Germany,November2004

17
Futurshow3004,Milan,Italy,November2004
12thAnnualWorldCongressonAntiAgingMedicine,LasVegas,NV,USA,December2004
BIOMEDEX2005,Montreal,Canada,March2005
IHEUAppignaniHumanistCenterforBioethics,1stConference,NewYork,NY,USA,April2005
2ndThefutureoflifeandthefutureofourcivilizationsymposium,Frankfurt,Germany,May2005
2ndAntiAgeingConferenceLondon,London,UK,May2005
WorkshoponModelsintheBiodemographyofAging,Berkeley,CA,USA,June2005
FENSSummerSchool,Coimbra,Portugal,July2005
TEDGLOBAL(Technology,Entertainment,Design)conference,Oxford,UK,July2005
17thSpoletoScienzaconferenceAlteringHumanDestiny,Spoleto,Italy,July2005
ErisSociety,25thannualconference,Aspen,CO,USA,August2005
InternationalAssociationofBiomedicalGerontology,11thCongress,Aarhus,Denmark,August2005
10thFutureofHealthTechnologySummit,Cambridge,MA,USA,September2005
4thRNAOInternationalElderCareConference,Toronto,Canada,September2005
ConservativePartyConference2005,Blackpool,UK,October2005
LouisVuittonMoetHennessysymposiumonmitochondria,Paris,France,October2005
EuropeanSocietyforCosmetic&AestheticDermatologySocietyMtg.,London,UK,October2005
ForesightInstitute2005VisionWeekend,SanFrancisco,CA,USA,October2005
ImmortalityInstitute,1stConference,Atlanta,GA,USA,November2005
58thAnnualMeeting,GerontologicalSocietyofAmerica,Orlando,FL,USA,November2005
NordicExceptionalTrendshop2005,Copenhagen,Denmark,November2005
22ndHumanGeneticsCommissionPlenaryMeeting,November2005
9thGoodenoughconferenceAge&Ageing:JusttheConcernoftheOld?,London,UK,Dec.2005
AAASAnnualMeeting,St.Louis,MO,USA,February2006
TED(Technology,Entertainment,Design)2006,Monterey,CA,USA,February2006
VodafoneFoundationsymposium,Madrid,Spain,March2006
1stWorldForumonScienceandCivilisation,Oxford,UK,March2006
1stBerkeleyStemCellRetreat,Asilomar,CA,USA,March2006
CalorieRestrictionSociety,4thConference,Tucson,AZ,USA,April2006
HumanEnhancementTechnologiesandHumanRights,Stanford,CA,USA,May2006
Transvision2006,Helsinki,Finland,August2006
1stENHANCEWorkshopontheExtensionofLifespan,CesanoMaderno,Italy,September2006
5thEuropeanCongressofBiogerontology,Istanbul,Turkey,September2006

18
2ndWomensForumfortheEconomyandSociety,Deauville,France,October2006
6thAlcorConferenceonExtremeLifeExtension,Scottsdale,AZ,USA,October2006
LivingWellto100,2ndConference,Boston,USA,November2006
3rdWorldMysteryForum,Interlaken,Switzerland,November2006
AmericanAcademyofReligion,2006AnnualMeeting,Washington,DC,USA,November2006
RomeScienceFestival,Rome,Italy,January2007
LondonTechnologyNetwork:StemCellsandRegenerativeMedicine,London,UK,March2007
EdmontonAgingSymposium,Edmonton,Canada,March2007
UBSGlobalInvestorsForum,London,UK,April2007
GermanSocietyofAntiAgingMedicine,7thConference,Munich,Germany,May2007
2ndENHANCEWorkshopontheExtensionofLifespan,CesanoMaderno,Italy,May2007
InternationalAssociationofBiomedicalGerontology,12thCongress,Spetses,Greece,May2007
6thCheltenhamScienceFestival,Cheltenham,UK,June2007
6thIntl.Conf.onIntelligentProcessingandManufacturingofMaterials,Salerno,Italy,June2007
OxfordConferenceonGeneticsandJustice,Oxford,UK,July2007
NationalCouncilforPalliativeCare,15thAnniversarySymposium,London,UK,July2007
CEPSsymposiumEuropefacingageingeconomicperspectives,Prague,CzechRep.,July2007
InstituteforEthicsandEmergingTechnologiessymposium,Chicago,IL,USA,July2007
Transvision2007,Chicago,IL,USA,July2007
SecretGardenParty,KingsRipton,UK,July2007
4thAntiAgeingConferenceLondon,London,UK,September2007
12thFutureofHealthandTechnologyInstituteConference,Cambridge,MA,USA,September2007
Gadgetoff,NewYork,NY,USA,September2007
7thAlcorConferenceonExtremeLifeExtension,Scottsdale,AZ,USA,October2007
3rdEuropeanAntiAgingCongress,Paris,France,October2007
8thAsia/OceaniaRegionalCongressofGerontology&Geriatrics ,Beijing,China,October2007
AmericanAcademyofReligion,2007AnnualMeeting,SanDiego,CA,USA,November2007
HewittsLocalGovernmentPensionServicesymposium,London,UK,January2008
FutureofGIHealthSummit,Boston,MA,USA,January2008
BIL2008,Monterey,CA,USA,March2008
CenterforBioethics&HumanDignity,1stAnnualPhoenixConf.,Phoenix,AZ,USA,March2008
AntiAgingMedicineWorldCongress,Paris,France,April2008
34thAsilomarMicrocomputerWorkshop,Asilomar,CA,USA,April2008

19
SeoulDigitalForum,Seoul,Korea,May2008
ERBIs10thAnnualBioPartneringExchange,Hinxton,UK,May2008
HewlettPackardWorldwideHealthandLifeSciencesSymposium,Orlando,FL,USA,May2008
ItalianAcademyofAntiAgingMedicine,3rdNationalCongress,May2008
LifeLinkconference,Gleneagles,UK,May2008
ThinkingDigital,Gateshead,UK,May2008
AntiAgeingSkinCareConference2008,London,UK,June2008
IdeaCity08,Toronto,Canada,June2008
BioBarCamp,MountainView,CA,USA,August2008
SciFoo,MountainView,CA,USA,August2008
EuropeanCongressonAntiAgingandAestheticMedicine,Dusseldorf,Germany,September2008
13thFutureofHealthandTechnologyInstituteConference,Cambridge,MA,USA,September2008
InternationalWorkshoponpostponingageing,Tallinn,Estonia,October2008
2008ConferenceoftheLibertarianAlliance,London,UK,October2008
4thEuropeanFuturistsConference,Lucerne,Switzerland,October2008
TheFuture,Hamburg,Germany,October2008
SummitontheGlobalAgenda,Dubai,November2008
ChangingtheWorld,Toronto,Canada,November2008
Convergence08,MountainView,CA,USA,November2008
ASUworkshoponthesystemsbiologyofaging,Tempe,AZ,USA,December2008
BIL2009,Monterey,CA,USA,February2009
WorkshoponAntiAgingMedicine,Volterra,Italy,March2009
4thWorldCongressofRegenerativeMedicine,Bangkok,Thailand,March2009
EisaiSymposiuminNeuroscience,London,UK,April2009
InternationalAssociationofBiomedicalGerontology,13thCongress,Montreal,Canada,May2009
MetanexusConference,Phoenix,AZ,USA,July2009
LifeAid,Brussels,Belgium,September2009
WorldStemCellSummit,Baltimore,MD,USA,September2009
GlennFoundationSymposiumontheBiologyofAging,Cambridge,MA,USA,September2009
14thFutureofHealthTechnologySummit,Cambridge,MA,USA,September2009
IQPCLifeSettlementsSummit,NewYork,NY,USA,October2009
SingularitySummit,NewYork,NY,USA,October2009
2ndEuropeanConferenceonAntiAgingandAestheticMedicine,Mainz,Germany,October2009

20
WomensForumGlobalMeeting,Deauville,France,October2009
BrocherFoundationsymposium,Geneva,Switzerland,October2009
TEDMED2009,SanDiego,CA,USA,October2009
BIL:PIL,SanDiego,CA,USA,October2009
ManhattanBeachProject,ManhattanBeach,CA,USA,November2009
UKSocietyofCosmeticScientists,London,UK,December2009
Systemsbiologyofaging,2ndannualconference,Baltimore,MD,USA,December2009
LIFT,Geneva,Switzerland,May2010
AntiAgingMedicineconference,Lisbon,Portugal,May2010
AmericanAgingAssociation,Portland,OR,USA,June2010
WorldFutureSociety,Boston,MA,USA,July2010
EuropeanRespiratorySociety,Barcelona,Spain,September2010
OurCommonFuture,Essen,Germany,November2010