Uses and Dosage of Barbiturates

Agent
Thiopental

HS

Total Volume Use

induction
sedation

Route
iv
iv

Uses and Dosage of Benzodiazepines

Agent
Diazepam

HS
5 mg
5 mg/ml

Midazolam

5 mg/ml

Lorazepam

2 mg

Total Volume Use

Premedication
Sedation
Induction
1 ml
Premedication
Sedation
Induction
Premedication

Route
oral
iv
iv
im
iv
iv
Oral

Uses and Dosage of Opioids

Agent
Morphine

HS
1 mg/ml

Pethidine

10 mg/ml

Fentanyl

50 mcg/ml

Total Volume Use

Premedication
Intra op analgesia
Post op analgesia
Premedication
Intra op analgesia
Post op analgesia
2 ml
Pre Induction
Intra op analgesia
Post op analgesia

Route
im
iv
iv
im
iv
iv
iv
iv
iv

Uses and Dosage of Ketamine, Etomidate and Propofol

Agent
Ketamine

HS
50 mg/ml

Etomidate
Propofol

2 mg/ml
10 mg/ml

Total Volume Use

Induction
Induction
Analgesia
Induction
20 ml
Induction
Maintenance
Sedation

Route
iv
im
iv
iv
iv
iv
iv

Uses and Dosage of Muscle Relaxants

Agent
Succinylcholine

HS
20 mg/ml

Rocuronium

10 mg/ml

Atracurium

10 mg/ml

Total Volume Use

Intubation
Maintenance
Infusion
5 ml
Intubation
Maintenance
Infusion
Intubation
Maintenance

Route
iv
iv
iv
iv
iv
iv
iv
iv

Infusion

iv

Uses and Dosage of Local Anesthetic

Agent
Bupivacaine
Lidocaine

HS
5 mg/ml
20 mg/ml

Total Volume Use

All
All

Route
iv
iv

Uses and Dosage of Anticholinergic

Agent
Atropine

HS
0.5 mg/ml

Total Volume Use

Route
iv

Uses and Dosage of Cholinesterase Inhibitors

Agent
Neostigmin

HS
1 mg/ml

Total Volume Use

Reverse Relaxants

Route
iv

Uses and Dosage of Adrenergic Agonist

Agent
Clonidine

HS
0.5 mg/ml

Ephedrine

50 mg/ml

Total Volume Use

Antihipertensive
Intrathecal
Epidural
Hypotension

Route
iv

iv

Uses and Dosage of Gastro Intestinal Related Drugs

Agent
Ranitidin
Omeprazole
Metoclopramide

HS
25 mg/ml
20 mg
10 mg/ml

Total Volume Use

Increase Gastric pH
Increase Gastric pH
Anti Emetic

Route
iv
po
iv

Uses and Dosage of Adjunct Anesthesia

Agent
Ketorolac

HS
30 mg/ml

Tramadol
Paracetamol

50 mg/ml
10 mg/ml

Ondansetron
Naloxone

4 mg/ml
1 mg/ml

Dexamethasone
Diphenhydramine

5 mg/ml

fgmikee@gmail.com

Total Volume Use

Analgesia
Post op analgesia
Analgesia
Analgesia
Post op analgesia
Anti Emetic
Opioid Reverse
Continous
Anti emetic

Route
iv
po
iv
iv
po
iv
iv
iv
iv

Dose (mg/kg)
3-6
0.5-1.5

Onset
30-60 sec
30-60 sec

Duration
20-30 min
20-30 min

Half-Time
5.5 - 26 hr

Peak Plasma
30 sec

Metabolism

Dose (mg/kg)
0.2-0.5
0.04-0.2
0.3-0.6
0.07-0.15
0.01-0.1
0.1-0.4
0.05

Onset
15-45 min
1-5 min
1-5 min
15 min
2-3 min
2-3 min
45 min

Duration
7-8 hr
15-60 min
15-60 min
1 hr
20-40 min
20-40 min
12-24 hr

Half-Time
20 - 100 hr

Peak Plasma
15 - 60 min

Metabolism
Liver

1.8 - 6.4 hr

30 min

Liver

9 - 16 hr

1.5 - 2 hr

Liver

Dose (mg/kg)
0.05-0.2
0.1-1
0.03-0.15
0.5-1
2.5-5
0.2-0.5
1-3 mcg/kg
2-150 mcg/kg
0.5-1.5 mcg/kg

Onset

Duration
7 hr
7 hr
7 hr
2-4 hr
2-4 hr
2-4 hr
30-60 min
30-60 min
30-60 min

Half-Time
2 - 3 hr

Peak Plasma
20 min

Metabolism
Liver

3 - 5 hr

30 min
1 min
1 min
30 - 60 min

Liver

Half-Time
2.5 - 3 hr

Peak Plasma
1 min
10-15 min

Metabolism
Liver

15-30 min
15-30 min
rapid
rapid
rapid
6 min
6 min
6 min

Dose (mg/kg)
1-2
3-5
0.05-0.1
0.2-0.5
1-2.5
50-200 mcg/kg
25-100 mcg/kg

Onset
30 sec
30 sec
30-60 sec
30-45 sec
30-45 sec
30-45 sec

Duration
5-10 min
5- 10 min
5-10 min
3-5 min
20-75 min
20-75 min
20-75 min

Dose (mg/kg)
1-1.5
0.15
2-15
0.6-1.2
0.15
3-12 mcg/min
0.4-0.5
0.1

Onset
30-60 sec
30-60 sec
30-60 sec
1-2 min
1-2 min
1-2 min
2-2.5 min
2-2.5 min

Duration
2-10 min
2-10 min
2-10 min
30-60 min
30-60 min
30-60 min
20-35 min
20-35 min

2 - 4 hr

75 min
30 - 60 min

Liver

4 - 8 min

Liver + Plasma
Liver

Half-Time

Peak Plasma
1-2 min

Metabolism
Plasma

1 - 2 min
14 - 18 min

4 min

Liver

17 - 21 min

3-5 min

Plasma

4-12 mcg/min

2-2.5 min

20-35 min

Toxic (mg/kg)
3
4.5

Onset
15-30 min
45-90 sec

Duration
1.5-8 hr
10-20 min

Half-Time
3.5 hr
1.5 - 2 hr

Peak Plasma
30-45 min
10-15 hr

Metabolism
Liver
Liver

Dose (mg/kg)
0.01-0.02

Onset
< 1 hr

Duration
4 hr

Half-Time
2 hr

Peak Plasma
30 min

Metabolism
Liver

Dose (mg/kg)
0.04-0.08

Onset
5-10 min

Duration
2.5 - 4 hr

Half-Time Peak Plasma Metabolism

50 - 90 min
20-30 min
Plasma + Liver

Dose (mg/kg)
1-3 mcg/kg
75-150 mcg
30 mcg/hr
0.1

Onset
< 1 hr
< 1 hr
< 1 hr
rapid

Duration
6-10 hr
6-10 hr
6-10 hr
60 min

Half-Time
12 - 33 hr

Peak Plasma
3-5 hr

Metabolism
Liver

3 - 6 hr

2-4 hr

Liver

Dose (mg/kg)
1 - 2.5
0.35
0.25 - 1.8

Onset
1-2 hr
1 hr
1-3 min

Duration
4 - 5 hr
12-24 hr
1-2 hr

Half-Time
2 - 3 hr
0.5 - 1 hr
5 - 6 hr

Peak Plasma

Metabolism
Liver
Liver
Liver

Dose (mg/kg)
0.25-1

Onset
1-3 min
30-60 min
45-60 min
15-30 min

Duration
6-8 hr
6-8 hr
9 hr
2-5 hr

Half-Time
3.5 - 9.2 hr
3.5 - 9.2 hr
5.5 - 7 hr
1 - 4 hr

Peak Plasma
1-3 min
1 hr
1.5 hr
0.25 hr
6 hr

5 min
1-2 min
1-2 min

12 hr
30-45 min

5.7 hr
1 - 1.5 hr

1-3
10-15
10-15
0.15
1-4 mcg/kg
5 mcg/kg/hr

0.5 - 3.5 hr

Metabolism
Liver
Liver
Liver
Liver
Liver
Liver

Excretion

Dosing Interval

Excretion
Kidney

Dosing Interval

Kidney + GI

Kidney

Excretion
Kidney + GI

Dosing Interval

Kidney

Kidney + GI

Excretion
Kidney + GI

Dosing Interval

Kidney
Kidney

Excretion
Kidney

Kidney

Kidney + GI

Dosing Interval

Excretion
Kidney
Kidney

Dosing Interval

Excretion
Kidney

Dosing Interval

Excretion
Kidney

Dosing Interval

Excretion
Kidney

Dosing Interval

Kidney

Excretion
Kidney
Kidney
Kidney

Dosing Interval

Excretion
Kidney + GI
Kidney + GI
Kidney
Kidney
Kidney
Kidney
Kidney

Dosing Interval
q6
q6
q8
q6
q6

POST OP ORDER MNEMONICS

V
O
S
T
P
E
D
I
A
R

POST OP ORDER MNEMONICS

Monitor vital signs (HR, BP, RR, spO2) q15 for 2 hours then q30 until stable
Give Oxygen 6 LPM via face mask
Suction if nescessary
Give warm blankets or may add warmer if necessary
Position supine with 30 degree head elevation
Educate patient to take a deep breath once in a while
Diet as tolerated
IVFD lactated ringers 110 ml/hr (70 kg) to follow PNSS 110 ml/kg
Medication : Ketorolac 30 mg po q8 / Paracetamol 1g po q6 / Tramadol 100 mg po q6
Referal

EXTUBATION CRITERIA
No
1
2
3
4
5
6
7

SUBJECTIVE
Clear oropharynx/hypopharynx
Intact gag reflex
Minimal end expiratory volatile anesthetics
Adequate pain control
Follows command
Sustained head lift for 5 sec
Sustained hand grasp

OBJECTIVE
Tidal Volume > 6 ml/kg
Peak voluntary negative inspiratory pressure > 20 cm H2O
Vital capacity > 10 ml/kg
Dead space to tidal volume ratio < 0.6
Sustained tetanic contraction (5sec)
T1/T4 ratio > 0.7
Alveolar-arterial PaO2 gradient (FiO2 1.0) < 350 mmHg