Anda di halaman 1dari 27

OBAT ANTI ANGINA

OLEH : KELOMPOK I
ENDRO CAHYONO
RUDI HARYANTO
NANI ROHAINI
ANA SUSANTI
DWI MURTI LESTARI

OBAT OBAT ANTI ANGINA


Anti Agregasi Platelet
Nitrates
Beta-adrenergic Blockers
Calcium Channel Blocking
Agents
4

Antiplatelet aggregation
therapy
Obat lini pertama /
Kelas 1 dari angina.
Jenis obat anti
agregasi platelet:
Aspirin
Clopidogrel
(Plavix)
5

Indikasi
Mengurangi kejadian aterosklerosis pada
pasien pada serangan jantung akut, MI
atau penyakit arteri perifer (PAD).
Mengurangi kejadian aterosklerosis pada
pasien dengan ACS(acute coronary
syndrome) seperti pada pasien post
PTCA with or without stent placement or
CABG
6

Nursing Intervention
Hati hati dengan resiko perdarahan
Efek platelet berkurang dalam waktu 5
hari setelah di hentikan

ASPIRIN

CLOPIDOGREL

Nitrates
Vasodilators
Sebagai lini Ke dua
Mengurangi kebutuhuan oksigen
miokard dan meningkatkan perfusi
koroner
Contoh obat : Nitroglycerin

10

Indications
Profilaksis untuk mencegah atau
mengurangi serangan angina atau
terhadap serangan angina kronis.
Heart failure after an MI

11

Nursing Interventions
Hati-hati pada pasien dengan hipotensi dan
hipovolum
Monitor TTV dengan ketat

12

NTG

13

Beta-adrenergic Blockers
Direct decrease in myocardial contractility, HR,
BP all of which reduce the myocardial O2
demand
Decrease morbidity and mortality rates in pts
with CAD (e.g. AMI)
Sedian obat : Atenolol, Bisoprolol, Metoprolol
tartrate,, Propanolol hydrochloride.

14

contBeta-adrenergic
Blocker
Antacid memperlambat absorpsi Beta Blocker,
NSAIDs menurunkan keefektifan beta bloker.
Efek samping : Bradycardia, angina, aritmia
(AV Block), peripheral edema, shock, nausea,
vomitus, diare, retensi air.

16

Indications
Hypertension
Angina secondary to
atherosclerosis
Cardiac arrhythmias,
especially: SVT, VT
(induced by digitalis)
Prevention of another
MI
17

Nursing Intervention

Monitor BP, HR
Monitor activity tolerance
Monitor liver enzymes, renal function studies
Instruct patient to change positions slowly to
avoid syncope episodes
Monitor for S/S of respiratory distress
Monitor for hyper and hypoglycemia
Take with foods to decrease GI side effect
(nausea, diarrhea).
18

BETA BLOCKER

19

Calcium Channel Blocking


Agents

Systemic vasodilation
Decreased myoardial contractility
Coronary vasodilation
Depressant effect on the SA node rate of
discharge, and the condution velocity
through the AV node, thus slowing the
HR.
Norvask, Verapamil, nifedipin
20

Indications
Hypertension
Prinzmetals angina:
Chest pain caused by vasospasm of the coronary
arteries usually occurring at rest rather than
during exercise.

Chronic stable angina


A-fib or flutter; Paroxysmal
supraventricular tachycardia
21

Nursing Interventions
Monitor BP, HR, heart rhythm
Monitor liver enzymes, renal function
Do not chew or divide, sustained-release
tabs (SR or XL tabs)
Take with food to increase absorption
Assure stool softener is ordered to
prevent constipation
22

Prinzmetal's angina
(variant angina)
What can you tell
about Prinzmetals
angina?
How is it different
from typical angina?

23

Prinzmetals angina, also called variant


angina, is chest pain (angina) that occurs
at rest for no apparent reason unlike
typical angina which usually follows
physical exertion. Attacks of Prinzmetals
angina are brief but painful and occur
most often at night
24

The cause of Prinzmetals angina is a coronary


artery spasm, in which the walls of the artery
briefly narrow (constrict). This temporarily
reduces or obstructs blood flow to the heart
muscle, resulting in chest pain. Coronary artery
spasms can be associated with
atherosclerosis.
Treatment of Prinzmetals angina is directed at
the underlying cause, such as atherosclerosis.
25

26

QEUSTIONS??????

27