T1
Posttreatment/Post Waitlist
BEP
Waitlist
BEP
Waitlist
Outcome Measure
(n = 16)
(n = 14)
(n = 16)
(n = 14)
CAPS total score
78.6 (16.0)
73.4 (19.2)
60.8 (32.8)
66.4 (20.0)
HADS anxiety
14.4 (2.6)
13.8 (2.5)
12.2 (4.2)
13.5 (3.1)
HADS depression
13.4 (4.8)
10.7 (3.5)
10.8 (5.8)
11.4 (4.2)
40.1 (19.5)
47.2 (13.5)
48.9 (24.2)
45.5 (20.4)
PGI total scoreb
aIntention-to-treat, last observation carried forward. Data are expressed as mean scores (SD).
bn = 13 for the waitlist group.
Abbreviations: BEP = brief eclectic psychotherapy, CAPS = Clinician-Administered PTSD Scale,
HADS = Hospital Anxiety and Depression Scale, PGI = Posttraumatic Growth Inventory.
T2
Follow-Up
BEP
(n = 16)
58.1 (30.5)
11.8 (5.4)
11.4 (5.6)
44.2 (26.1)
Source
df
1
1
1
1
25
1
1
1
1
25
1
1
1
26
1
1
1
1
24
Mean Square
7,168.72
1,086.13
775.04
2,430.19
305.87
44.39
59.86
1.95
45.68
9.26
432.15
15.39
79.44
10.41
3,809.51
1,159.26
999.99
2,151.34
171.32
F
23.44***
3.55
2.53
7.95**
T0 CAPS
T0 HADS depression
Lifetime traumatic events
Group
Error
HADS anxiety
T0 HADS anxiety
4.80*
T0 HADS depression
6.47*
Lifetime traumatic events
0.21
Group
4.93*
Error
HADS depression
T0 HADS depression
41.51***
Lifetime traumatic events
1.48
Group
7.63*
Error
PGI total score
T0 PGI total score
22.24***
T0 HADS depression
6.77*
Lifetime traumatic events
5.84*
Group
12.56**
Error
aN = 30, except N = 29 for PGI.
*P < .05.
**P < .01.
***P < .001.
Abbreviations: BEP = brief eclectic psychotherapy, CAPS = Clinician-Administered PTSD Scale,
HADS = Hospital Anxiety and Depression Scale, PGI = Posttraumatic Growth Inventory.
Partial 2
.48
.12
.09
.24
.16
.21
.01
.17
.62
.05
.23
.48
.22
.20
.34
JCClin
OPYRIGHT
2011
PHYSICIANS
.
Psychiatry
72:4,
April 2011 POSTGRADUATE PRESS, INC. COPYRIGHT 2011 PHYSICIANS POSTGRADUATE PRESS, INC
565
11.
12.
13.
14.
15.
16.
17.
Ulrich Schnyder, MD
ulrich.schnyder@access.uzh.ch
Julia Mller, PhD
Andreas Maercker, PhD, MD
Lutz Wittmann, PhD
Author affiliations: Department of Psychiatry and Psychotherapy, University Hospital Zurich (Drs Schnyder, Mller, and Wittmann); and Department of Psychology:
Psychopathology and Clinical Intervention, University of Zurich (Dr Maercker),
Zurich, Switzerland. Potential conflicts of interest: The authors report no potential
conflicts of interest relevant to the subject of this letter. Funding/support: This study
was supported by the Swiss National Science Foundation (3200B0-102204.03), Olga
Mayenfisch Foundation, Hermann Klaus Foundation, and the Zurich University
Jubilumsspende. Previous presentation: Presented at the 3rd National Conference on
Psychotherapy; May 12, 2010; Jakarta, Indonesia; and the 20th IFP World Congress
of Psychotherapy; June 1619, 2010; Lucerne, Switzerland. Trial registration: clinicaltrials.gov Identifier: NCT00329992.
doi:10.4088/JCP.10l06247blu
Copyright 2011 Physicians Postgraduate Press, Inc.
REFERENCES
1. Foa EB, Keane TM, Friedman MJ, et al. Effective Treatments for PTSD.
Practice Guidelines From the International Society for Traumatic Stress
Studies. 2nd ed. New York, NY: Guilford; 2009.
2. Schnyder U. Why new psychotherapies for posttraumatic stress disorder?
Psychother Psychosom. 2005;74(4):199201. doi:10.59/842PubMed
3. Gersons BPR, Carlier IVE, Lamberts RD, et al. Randomized clinical trial
of brief eclectic psychotherapy for police officers with posttraumatic
stress disorder. J Trauma Stress. 2000;13(2):333347. doi:10.23/A7986PubMed
4. Lindauer RJL, Gersons BPR, van Meijel EPM, et al. Effects of brief
eclectic psychotherapy in patients with posttraumatic stress disorder:
randomized clinical trial. J Trauma Stress. 2005;18(3):205212. doi:10.2/jts9PubMed
5. Lindauer RJL, Booij J, Habraken JBA, et al. Effects of psychotherapy on
regional cerebral blood flow during trauma imagery in patients with
post-traumatic stress disorder: a randomized clinical trial. Psychol Med.
2008;38(4):543554. doi:10.7/S329 4PubMed
6. Lindauer RJL, Vlieger EJ, Jalink M, et al. Effects of psychotherapy on
hippocampal volume in out-patients with post-traumatic stress disorder:
a MRI investigation. Psychol Med. 2005;35(10):14211431. doi:10.7/S329546PubMed
7. Lindauer RT, van Meijel EP, Jalink M, et al. Heart rate responsivity to
script-driven imagery in posttraumatic stress disorder: specificity of
response and effects of psychotherapy. Psychosom Med. 2006;68(1):
3340. doi:10.97/psy856302.e7PubMd
8. Olff M, de Vries GJ, Gzelcan Y, et al. Changes in cortisol and DHEA
plasma levels after psychotherapy for PTSD. Psychoneuroendocrinology.
2007;32(6):619626. doi:10.6/jpsyneu274.01PbMd
9. Blake DD, Weathers FW, Nagy LM, et al. Clinician-Administered PTSD
Scale for DSM-IV, Revised July 98. Boston, MA: National Center for
Posttraumatic Stress Disorder; 1998.
10. Bernstein DP, Stein JA, Newcomb MD, et al. Development and validation