1.

A prescription of 120 ml of KMnO4 will be prepared as such that 5 mal of that

solution diluted to 500ml gives 1: 2500. How many grams KMnO4 is needed?

2.

35 mg of prednisolone used for first 2 days. Then every 2 days 5 mg is

reduced. How many days it will take for ending up the regimen?

3.

Azithromycin preparation is available as:

a) 300 mg 15 ml (100mg/5ml)
b) 600 mg 15 ml (200mg/5ml)
c) 900 mg 22.5 ml (200mg/5ml)
d) .30 ml (mg/5ml)
e) .37.5 ml (mg/5ml).
One child is prescribed 300mg azithromycin for 1 st day and then 150mg from
day 2nd to day 5th. Which of the above preparation will be dispensed?

4.

Which of the following test is not for cancer screening?

a) pep
b) colonoscopy
c) blood work

5.

Which of the following drug has side effects of hyperkalemia, gynocomastia

and hypovolumia? Ans: Spironolactone

6.

Chemical structure of amphetamine was given. What is the mechanism of

this product?

7.

Structures were given for a reaction in which ester is converted to acid.

Which enzyme is responsible for this reaction? Ans: esterase

8.

Sterile WFI USP is:

a) sterile
b) pH 7.4

9.

What is the Mechanism of action of varnericline:

10.

Which one acts as humectant, cosolvent and preservative?

a) ethanol
b) glycerin

11.

A formula of w/o was given where egg yolk was used. The question was what
is the purpose of using egg yolk? Ans: emulsifying agent

12.

Methyl paraben and propyl paraben are used together. That is the purpose of
using both together? Ans: to get synergestic preservative action

13.

Another formulation was given. In that formulation polysorbate 80 was used?

What was the purpose of using polysorbate 80? Ans: solubilizing agent

14.

Which medication is filled only by written rx? Ans: hydrocodone

15.

Which one is the correct statement regarding amphetamine

16.

Structure of steroid ring was given. There was hydroxyl and aldehyde group
at carbon 11 and 13 position of the steroid ring. What is the name of the
structure when CHO group of carbon 13 make a ring with carbon 11?
a) acetoacetic acid
b) hemiacetal

17.

Which of the antidandruff product bleach on hair?

a) selenium sulfide
b) coal tar

18.

Which oral medication is used for acne preparation?

19.

If oral or topical antibiotic is ineffective in cystic acne then which medication

will be used: (options were: isotretinonin, tetracycline,..)

20.

Which one is not effective of excessive insulin administration?

a) Nausea
b) Diarrhoea
c) sweating
d) palpitation

21.

Deficiency of ADH causes:

I)
Polyurea
II)
Polydpsea
III)
decrease in blood osmolarity

22.

Which one of the following is monitored in lithium therapy:

function test

23.

Drug A follows 1st order kinetics. How the elimination rate constant is
determined from the time-plasma drug concentration curve of IV dose of drug
A?
Ans: finding slope of ln A and time.

24.

The plasma drug concentration at different time interval is given as follows:

Calculate the plasma half-life.

25.

AUC is partially used to determine:

26.

Head lice shampoo is used after 7 days of 1st use. What is the reason?

27.

What does Atherosclerosis mean?

Ans: Thyroid

Ans: bioavailability

28.

Which of the following means 1 tablet 4 times a day after meal and at
bedtime?
Ans 1 tab QID pc and hs

29.

Opioid drug acts on which of the following receptor?

30.

All are the reason of the drug non-compliance of antidepressant except:

a) GI bleeding
b) Sedation
c) weight loss
d) Insomnia
e)

31.

Which of the following drug does not decrease the efficacy of oral
contraceptives?
A) Carbamazepine
b) Phenytoin
c) Gabapentin
d) ..
e) .

32.

Metronidazole is used for all indication except:

a) Gonorrhea
b) Anerobic infection
c) trichomiasis
d) ..
e) ..

33.

Which drug can be given irrespective of food?

A) amoxicillin
b) bisphosphonate
c) cefuroxime
d) ..
e) ..

34.

Which drug is not given in pregnancy? Ans: Ramipril

35.

A patient is using Brimaprost for last three months. Which of the following
can happen due to the drug use?

36.

A patient was admitted to emergency for alcohol withdrawal effect. Which of

the following drug can be given to the patient?

37.

What is true about schedule F drug? (Answer options were regarding

advertisement of the drug)

38.

Which one is not used for acute gout attack? Ans: Allopurinol

39.

Which one does not have neuclic acids?

A) virus
B) helminthes

c)

Ans: mu receptor

d)..

40.

Which one is true regarding Canadian Health Care system?

41.

Calculation regarding net profit increment over last year

42.

What is true regarding p value in an unpaired t-test of two groups of students

about average weight?
Ans: The greater the p value the greater
chance that the average weight of two groups are different

43.

A problem was regarding NNT calculation

44.

Calculation regarding Absolute risk reduction

45.

Which one is not under the 4Ps of marketing concept?

46.

A pharmacy manager always takes decision without consulting other coworkers and he takes action whatever he thinks the best. Such type of
management is called:
Ans: Autocratic

47.

PEBC Sample question 88

48.

What do you mean by incidence rate?

49.

Which one is used to monitor efficiency and inventory control of a pharmacy?

Ans: Trunover

50.

All are the inhibitors of CYP3A4, except:

51.

Which one is used to treat constipation

52.

Which one is used as prophylactic of travelers diarrhoea?

A) Loperamide
b) Bismath subsalicylate

53.

Drug induced parkinsons disease is caused by which of the following drug?

54.

CBC is performed for which therapy?

a. Clozapine
b. carbamazepine

55.

There was a question regarding gene-therapy

56.

Pharmaceutical care focuses which of the following: (answer options was long
sentences)

57.

Which one is the main responsibility of a hospital pharmacist

care

58.

How sympathomimetic drugs act in glaucoma: (answer options were

regarding aqueous humor production and draining out aqueous humor)

Ans: Patient

59.

All are true in overactive immune system except:

a) increase histamine
b) decrease BP
c) Vasoconstriction

60.

Which one is not an autoimmune disease?

A) Systemic lupus erythematosus
b) Rhematoid Arthritis
c)
d) ..
e) ..

61.

Osteoporosis can be prevented by all except:

62.

All are risk factors of Deep vein thrombosis, except:

a) Pregnancy
b) Cancer & chemotherapy
c) progestin only OCP

63.

Reabsorption of Calcium from distal tubule due to:

a) parathyroid hormone
b) Vit D3

64.

Which type of blood cells are most affected by anticancer drugs?

A) Neutrophil
b) thrombocyte

65.

There was a question regarding zudovudine (AZT)

66.

Buffer is made up of weak acid and salt of strong base of that acid. Buffer
capacity is increased by:
I)
using strong acid
II)
choosing pKa of acid closer to pH of the preparation
III)
increase the concentration of both acid and salt

67.

All are true regarding pseudoplastic flow except:

a) Follow Newtons law
b) increase flow with shear stree
c) Some polymeric substance follow pseudoplastic flow
d) it is not possible to determine the rate of flow at a specific time
point

68.

There was a problem regarding Css calculation.

69.

PPI used in hyperacidity treatment. Which one is true for PPI?

increase absorption

70.

Which one is related to stomach acid?

A) Peptic ulcer
b) GERD

Ans: Acid

71.

Which antibiotic is not used in ulcers associated with H. pylori?

A) Amoxicillin
b) Clarithromycin
c) metronidazole
d) tetracycline
e) clindamycin

72.

All are counselled to a patient who is going for travel, Except:

a) avoid to take plenty of water
b) use compressor in legs

73.

Where is Growth hormone produced ?

a) Hypothalamus
b) anterior pituitary gland

74.

Which one is not given at bedtime due to insomnia?A) varenicline

75.

Which one is one of the prime objectives of using hospital formulary?

a) cost minimization ..
b) prescriber should use the drugs of minimum cost
c) to minimize the adverse effect

76.

Which one is not true about vitamin A:

a) deficiency may cause blindness
b) should be given in breast feeding child
c) beta-carotene may be used as supplement of vitamin A

77.

Influenza A contains:
a) Reverse Transcriptase
b) RNA
c) DNA

78.

Which type of RNA does contain message for protein synthesis?

Ans: mRNA

79.

Which of the following enzymes of virus is responsible for penetration into

host cell?
Ans: Neuroaminidase

80.

Which of the following is the structure of nitrosamine where R and R` shows

alkyl or aryl group?
Ans: RR`NN=O

81.

When proteoglycan transcription is formed? (Answer options was like, before

or after transcription or translation)

82.

Which of the following statement describe septal defect?

Ans: Leakage between wall that separates right and left side of heart

83.

Which of the following is the most expensive in the health care system in
Canada?
Ans: Salary of the health care professionals

84.

There was a question regarding naltrexone

85.

Which one is true regarding diazepam?

a) long term use for insomnia
b) cause fall down in elderly

86.

There was a question regarding Glutathione conjugation-

87.

What are the combination bases in DNA?

Ans: AT/GC

88.

Which of the following methods separates based on molecular size?

Ans: Gel electrophoresis

89.

Which one is false regarding Pellagra?

A) due to Niacin deficiency
b) failure to form niacin from tryptophan
c) It causes..
d).
E)

90.

What is true if essential amino acids are not supplied to body?

Ans: impair protein synthesis

91.

All causes protein denaturation, Except:

a) Fridge
b) heat
c) dilution with solven pH 7.4
Which one is used as anti-congestant in hypertensive patient?
Which one has sympathomimetic effect? Ans: dobutamine (others options
were anticholinergic drugs)
What does happen to the microorganism when topoisomerase II and
topoisomerase IV is used? Ans: apoptosis
What is seen in ECG in ventricular fibrillation? (options was about absent of p
wave, QT and others)
What happens in hypertrophy?
Ans: enlargement of cell without
division
Which one is formed in ketoacidosis? Ans: beta hydroxyl butyric acid
Which of the following system is involved in fat and cholesterol absorption? A)
lymphatic system b) Respiratory system
The following structure was given

92.
93.
94.
95.
96.
97.
98.
99.

100.
101.
102.
103.
104.
105.
106.
107.
108.
109.
110.
111.
112.
113.
114.
115.
116.
117.
118.
119.

120.
121.
122.
123.
124.
125.
126.
127.
128.
129.

Which of the following enzyme is responsible to break the ring: Ans:

lactamase
Which drug causes hot flushing?
Ans: Niacin
Which are the side effects of acarbose?
Ans: flatulence and
blotting
Type I anti-arrhythmic drug blocks:
Ans: Na ion channel
There was a question regarding leflunomide
Fishy odor and yellow creamy color vaginal discharge is the symptom of:
Ans: Bacterial vaginosis
How do herpes simplex virus spread? (one option was by direct contact)
For hearth failure, edema is one of the main symptoms. In left sided failure
edema occurs in the following organ: a) lung
b) Liver
All of the following drugs may have effect to eye, Except: a) Amiodarone
b) hydrochloroquine
c) Rifampin d) ethambutol
e)
isotretinoin
Which process is not applied in swelling of ankle injure?
Ans: Heat
One question was like Which is the renal threshold level of glucose or fasting
glucose??? And the answer option was in mm/litre)
There was a question regarding abscess
What is appropriate auxiliary label of clindamycin suspension? A) keep in
refrigerator b) Shake well before use
What do you mean Bathochromic Shift?
Ans: Absorption of light
from shorter wavelength to the longer wavelength
Which drug give bradycardia? A)
nifedipine
b) verapamil
Where to report the drug adverse effect errors:
Ans: Canadian
Medication Incident Reporting and Preventing System (CMIRPS)
Which one is not a symptom of allergic rhinitis?
What is most appropriate in case of dry skin? (one option was apply
moisturizing agents after bath when the skin is still dump)
There was a question regarding function of corticosteroid hormone
There was a question regarding definition and action of Heptane
How does the following drug act

What is true regarding of effervescent table? Ans: before administering

dissolve in water
Contact angle is a measurement of:
a) solubility b) dispersibility
c)
wettability
Which type of pharmacy is easy to open?
I) Franchise II) corporation
III) partnership