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Current as of: Thursday, May 27, 2010

Lung Cancer Workshop VII


Application of High Resolution CT Imaging Data to
Lung Cancer Drug Development: Measuring Progress
May 13 - 14, 2010 • Bethesda, Maryland

AGENDA
Day One - Thursday, May 13
7:30 AM Conference Registration
Grand Ballroom Foyer
8:00 AM Welcome
Grand Ballroom A & B Chairs:
 Carolyn R. “Bo” Aldigé, Prevent Cancer Foundation
 Thomas M. Baer, PhD, Optical Society of America (OSA), Stanford Photonics Research Center

8:10 AM Overview and Workshop Goals


James L. “Jim” Mulshine, MD, Rush University Medical Center

8:30 AM State-of-the-Art Lecture: Controlling Variability in Lung Cancer Response


Assessment
Ricardo S. “Rick” Avila, Kitware, Inc.

9:00 AM COPD and Lung Cancer: Shared Etiology and Opportunity


James P. Kiley, PhD, National Heart Lung and Blood Institute

9:30 AM Transforming Drug Development with Quantitative Imaging


P. David Mozley, MD, Merck & Co., Inc.

10:00 AM 15-Minute Break

10:15 AM Progress Toward Quantitative Imaging


Daniel C. Sullivan, MD, Duke University Medical Center

10:30 AM RSNA’s QIBA Volumetric CT: Progress and Plans


Andrew J. Buckler, MS, Buckler BioMedical LLC

11:00 AM The Zone of Transition: a Frontier of Image Processing and Lung Cancer
David F. Yankelevitz, MD, Mt. Sinai Medical Center

11:30 AM Accelerating Lung Imaging Research Through Open Science


Thomas M. Baer, PhD, OSA, Stanford Photonics Research Center
Sean Bagshaw, Optical Society of America (OSA)

12:00 PM Imaging Databases and Infrastructural Developments


Jonathan C. Silverstein, MD, PhD, University of Chicago

www.preventcancer.org
Lung Cancer Workshop VII
Application of High Resolution CT Imaging Data to
Lung Cancer Drug Development: Measuring Progress
May 13 - 14, 2010 • Bethesda, Maryland

Day One - Thursday, May 13 continued …


12:30 PM Lunch
Kenwood/Montrose/
Great Falls Room
1:30 PM Panel on Imaging Radiation Risk: Perception and Reality
Grand Ballroom A & B Moderator: David F. Yankelevitz, MD, Mt. Sinai Medical Center
Lawrence N. Rothenberg, PhD, Memorial Sloan Kettering Cancer Center

2:00 PM Panel: Volumetric Assessment Performance: What have we learned?


Moderator: David F. Yankelevitz, MD, Mt. Sinai Medical Center
QIBA Vol CT Group 1A: Nicholas Petrick, PhD, U.S. Food and Drug Administration (FDA)
QIBA Vol CT Group 1B: Andrew J. Buckler, MS, Buckler BioMedical
QIBA Vol CT Group 1C: Charles “Chuck” Fenimore, PhD, National Institute of Standards
and Technology (NIST)

2:30 PM Lessons Learned from a Quantitative Imaging Trial


Venice Archer, MD, Roche Products Limited

2:50 PM Introduction to Breakout Group Process (materials distributed in advance)


James L. “Jim” Mulshine, MD, Rush University Medical Center

2:55 PM 5-minute Break


3:00 – 3:45 PM Breakout Group Work Session 1
Potomac Room Group A:
Strategic Planning: Development Application of Imaging Databases
Facilitators: Ricardo S. “Rick” Avila, Kitware, Inc.
Thomas M. Baer, PhD, OSA, Stanford Photonics Research Center
Andrew J. Buckler, MS, Buckler BioMedical LLC

Bethesda Room Group B:


Strategic Planning: Clinical Trials Progress
Facilitators: David F. Yankelevitz, MD, Mt. Sinai Medical Center
Andreas Voss, MD, F. Hoffmann-La Roche Ltd.

3:45 PM 5-minute Break

3:50 PM CT Imaging Phenotypes in COPD


Grand Ballroom A & B Raul San Jose Estepar, PhD, Brigham and Women’s Hospital – Harvard Medical School

4:10 PM Quantitative Assessment of Pulmonary Hypertension


George R. Washko, MD, MMSc, Brigham and Women’s Hospital

4:30 PM Imaging in Clinical Trials: Past, Present and Future


• John J. Reilly, MD, University of Pittsburgh

4:50 PM CT Approach to Measuring Lung Injury During Cancer Detection Analysis


Claudia I. Henschke, PhD, MD, Mt. Sinai Medical Center

www.preventcancer.org
Lung Cancer Workshop VII
Application of High Resolution CT Imaging Data to
Lung Cancer Drug Development: Measuring Progress
May 13 - 14, 2010 • Bethesda, Maryland

Day One - Thursday, May 13 continued …

5:10 PM Panel: Accelerating Collaboration between Lung Cancer and COPD


Chairs:
 Ricardo S. “Rick” Avila, Kitware, Inc.
 Raul San Jose Estepar, PhD, Brigham and Women’s Hospital – Harvard Medical School
George R. Washko, MD, MMSc, Brigham and Women’s Hospital
John J. Reilly, MD, University of Pittsburgh
Claudia I. Henschke, PhD, MD, Mt. Sinai Medical Center
Antonello "Tony" Punturieri, MD, National Heart, Lung and Blood Institute, National Institute
of Health

5:30 PM Meeting Adjourns for the Day


6:30 PM Departure for Reception and Dinner, the Cosmos Club
If you plan to attend the reception and dinner, please be in the Marriott Bethesda’s lobby no
later than 6:15 PM to catch the bus to the Cosmos Club

www.preventcancer.org
Lung Cancer Workshop VII
Application of High Resolution CT Imaging Data to
Lung Cancer Drug Development: Measuring Progress
May 13 - 14, 2010 • Bethesda, Maryland

Day Two - Friday, May 14


7:30 AM Continental Breakfast
Grand Ballroom Foyer
8:00 AM NCI Current / Planned Initiatives and Resources: Imaging as a Biomarker
Grand Ballroom A & B Robert J. Nordstrom, PhD, National Cancer Institute (NCI)

8:30 AM Update on FDA Center for Devices and Radiological Health Investigation of
Quantitative CT through Anthropomorphic Phantom Studies
Nicholas Petrick, PhD, U.S. Food and Drug Administration (FDA)

9:00 AM Tumor Volume and Clinical Outcome - A role for Re-use of High Quality
Quantitative Image Databases?
Gudrun Zahlmann, PhD, F. Hoffmann-La Roche, Ltd.

9:30 AM The Critical Path Institute: Improving the Innovation Process


Marietta Anthony, PhD, Critical Path Institute

10:00 AM Breakout Group Work Session 2


Potomac Room Group A: Strategic Planning: Development Application of Imaging Databases
Facilitators: Ricardo S. “Rick” Avila, Kitware, Inc.
Thomas M. Baer, PhD, OSA, Stanford Photonics Research Center
Andrew J. Buckler, MS, Buckler BioMedical LLC
Bethesda Room Group B: Strategic Planning: Clinical Trials Progress
Facilitators: David F. Yankelevitz, MD, Mt. Sinai Medical Center
Nasser K. Altorki, MD, Cornell University Medical Center
Andreas Voss, MD, F. Hoffmann-La Roche Ltd.

11:00 AM Volcano 2009


Anthony P. “Tony” Reeves, PhD, Cornell University

11:30 AM Update on Neoadjuvant Trials


Nasser K. Altorki, MD, Cornell University Medical Center

Noon Lunch
Kenwood/Montrose/
Great Falls Room
1:00 PM Panel:
How to Collaborate to Accelerate Response Assessment for Lung Cancer
Grand Ballroom A & B
Ricardo “Rick” S. Avila, Kitware, Inc.
Thomas M. Baer, PhD, OSA, Stanford Photonics Research Center
Daniel C. Sullivan, MD, Duke University Medical Center
Robert J. Nordstrom, PhD, National Cancer Institute (NCI)
Gudrun Zahlmann, PhD, F. Hoffmann-La Roche, Ltd.
Jonathan C. Silverstein, MD, PhD, University of Chicago

1:30 PM Breakout Group Reports


Group A: Strategic Planning: Development Application of Imaging Databases
Group B: Strategic Planning: Clinical Trials Progress

2:30 PM Meeting Conclusion and Final Comments


James L. Mulshine, MD, Rush University Medical Center

2:45 PM Program Concludes

www.preventcancer.org