Fibromyalgia Etiology:
Populations,
Prevalence,
Incidence
Genetics
Infection
Physical/ Emotional
Trauma
Risk Factors
Increasing Age
Being a female
Rheumatic disease
Psychological distress for long- term
patients
Transmission
Genetics
Prevention
Neurologic
o Increased substanc P and Somatostatin
o Decreased serotonin, cortisol, magnesium, oxytocin,
thyroid hormon
Reproductive Hormone Dysfunction
o Decreased relaxin, testosterone,
Immune System Dysfunction
o Increased cytokines and activation of glial cells
Autonomic Nervous System Dysfunction
o Sympathetic and Parasympathetic imbalance
! Sympathetic is hyperactive
! Parasympathetic is hypoactive
o Circulatory system dysfunction
! Decreased circulation, low blood pressure,
increased heart rate
Issues with pain processing in CNS
Dysfunctional pain inhibition
Generalized pain
Stiffness
Fatigue
Poor sleep
Headaches
Paresthesia
o Tingling and numbness
Painful menstrual periods
Diagnostic Criteria
o Presence of multiple
tender points
o Symptom- based
assessment
o Symptom severity scale
and widespread pain index
Prognosis
Considerations for PT
Clinical Pearls
References:
1. Arnold LM, Fan J, Russell IJ, Yunus MB, Khan MA, Kushner I, Olson JM, Iyengar SK. The Fibromyalgia Family Study: A Genome-Wide Linkage Scan Study.
Arthritis & Rheumatism 2013:11221128.Accessed September 9, 2015
2. Centers for Disease Control and Prevention. Fibromyalgia. Http://www.cdc.gov/arthritis/basics/fibromyalgia.htm.Revied November 7, 2012. Acesed
September 9, 2015.
3. Koulil SV, Lankveld W V, Kraaim aat FW , Riel PLV, Evers AW . Risk factors for longer term psychological distress in well functioning fibromyalgia patients: A prospec tive study into prognostic factors. Patient Education and Counseling
2010;80(1):126 129. Available at: https://www.clinicalkey.com /#!/content/playcontent/1 - s2.0 s0738399109003668?returnurl=null&referrer=null . Accessed Septem ber 2015.
ber 2015.
4. Rodrigo L, Bianco I, Bobes J, et al. Effect of one year of a gluten - free diet on the clinic al evolution of irritable bowel syndrome
plus fibromyalgia in patients with associated lymphocytic enteritis: a case - control study . Arthritis Res Ther. 2014;16(4):421.
http://www.ncbi.nlm .nih.gov/pubm ed/25160886 Accessed September 9, 2015.
5. Efrati S, Golan H, Bechor Y, et al. Hyperbaric oxygen therapy can dimish fibromyalgia syndrome - prospective clinical trial. Plos
One. 2015; 10(5):e0127012. http://www.ncbi.nlm .nih.gov/pubm ed/26010952 Accessed September 9, 2015.
Accessed September 9, 2015.
6. W olfe F, Hassett AL, W alitt B, M ichaud K. M ortality in fibromyalgia: a stud y of 8,186
y of 8,186
patients over thirty - five years . Arthritis Car & Research. 2011;63(1):94 - 101.
http://onlinelibrary.wiley.com /doi/10. 1002/acr.20301/epdf . Accessed Septem ber 9, 2015.
7. Nijs J, M annerkorpi K, Descheemaeker F, VanHoudenhove B. Prim ary care physical therapy in people with fibrom yalgia:
opportunities and boundaries within a monodisciplinary setting. Physical Therapy. 2010;90(1 2):1815 - 1822.
http://web.a.ebscohost.com /ehost/pdfviewer/pdfviewer?sid=239da259 - 8801 - 4fe3 - aa36 6407bc3bfae2%40sessionmgr4004&vid=1&hid=4209 . Accessed Septem ber 9, 2015.
8. Cassisi G, Sarzi - Puttini P, Alciati A, et al.;Italian Fibromyalgia Network. Symptoms and signs in fib rom yalgia syndrom e.
Reum atism o. 2008;60(1):15 - 24. http://www.reum atism o.org/index.php/reum a/article/ view/reum atism o.2008.1s.15/351 .
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