Fall 2008
Open up Chemsketch
Fall 2008
Clean it up!
Tools Clean Structure or F9
Yes!
Lets modify our benzene into caffeine
Put in the atoms choose the atoms from the left menu.
Clean it up F9
Fall 2008
Fall 2008
Use selection tool (circled in red) to select structure before you push [Apply]
Fall 2008
And/Or you can select the structure and copy [Ctrl+C] to paste it into a word document
[Ctrl+V].
O
H3C
CH3
C
N
N
CH
N
CH3
Fall 2008
Then make two periods .. or a colon : and use them as your unshared pairs.
Highlight them and make them bold ([Ctrl]+[B])
You can move them around by pointing at them and dragging.
Holding down [Ctrl] as you drag allows you to copy them.
The problem is that they disappear as you drag them!
:O:
H3C .. C
N
C
:..O
C .. C
N
CH3
:N
CH
..N
H3C
Fall 2008
Draw you arc, then select the arrow icon to put on an arrow.
Copy your caffeine molecule, Edit Select All, [Ctrl] to copy and drag.
Add in a straight arrow.
:O:
H3C .. C
N
C
:..O
C .. C
N
CH3
:N
CH
H3C .. C
N
C
:..O
..N
CH3
:O:
H3C
C .. C
N
:N
CH
..N
H3C
Delete the curved arrow on the right structure and move the electrons from N to O.
:O:
H3C .. C
N
C
:..O
C .. C
N
H3C
CH3
:N
H3C
:..O
:N
C
N
CH
..N
CH3
..
:O:
C
C .. C
N
CH
..N
H3C
In Structure screen click on the C icon to get back to structure drawing tool to change
order of bonds (single/double)
Fall 2008
..
:O
+
H
..
Cl:
..
H3C
.. +
O
CH3
CH3
..
..
HCl:
Fall 2008
3D viewer:
Click on 3D Viewer
Space Filling
Fall 2008
10
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11
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12
H
C
HO
CH2
CH
HO
HN
HC
C
CH3
C
H
HO
HC
CH
HC
CH
HC
CH
CH
HC
CH
OCH3
O
HC
HC
CH
HC
HC
CH
CH
C
H
2-naphthol
benzoic acid
CH
HC
CH
HC
C
C
CH
C
H
HC
CH3
CH
C
OH
HC
HC
H
C
H
C
HC
Cl
C
H
diphenyl
acetaminophen
CH
C
C
HC
OH
HC
CH3
C
H
ephinephrine
(adrenalin)
H
C
H
N
H
C
HC
HC
C
CH
CH
NH2
4-chloroaniline
acetophenone
2-methoxy
naphthalene