Name

Diagnosis
Physician
DRUG DATA
Generic Name:
Hyoscine-Nbutylbromide
Trade Name:
Buscopan
Patients Dose:
10mg ivtt q8hrs
Minimum Dose: 1
tab bid
Maximum Dose:
100mg ivtt daily
Available Forms:
ampule, tablet
Route of
Administration:
P.O., I.V.

Age:
Sex:
Date of Admission:
CLASSIFICATION
Therapeutic:
Anticholinergic
Pregnancy risk
category: Category C
Pharmacologic:
antispasmodic, belladona
alkaloid

MECHANISM OF
ACTION
Pharmacokinetics:
Onset: immediate
Peak:unknown
Duration:
unknown
Half-life: 5 hrs
Chemical: acts by
interfering with the
transmission of nerve
impulses by
acetylcholine in the
parasympathetic
nervous system;
exerts a spasmolytic
action on the smooth
muscle of the
gastrointestinal,
biliary and urinary
tracts

Ht:
Wt:
Body Type:

INDICATION

CONTRAINDICATIONS

ADVERSE REACTIONS

NURSING
RESPONSIBILITIES

General:
Acute GI, biliary &
genitourinary spasm
including biliary &
renal colic.
Parenterally also as
an aid in diagnostic &
therapeutic
procedures (e.g.,
gastroduodenal
endoscopy, radiology)

Contraindicated in
patients:
-hypersensitive to the
drug
-with myasthenia
gravis, megacolon
and narrow angle
glaucoma
*use cautiously in
patients with hepatic
dysfunction

Patients:
Preoperative
medication

Interactions:
Drug-to-drug:
Intensifies
anticholinergic
effects of TCAs,
antihistamines,
quinidine,
amantadine,
disopyramide & other
anticholinergics (eg
tiotropium,
ipratropium).
Enhanced
tachycardiac effects
of -adrenergic
agents. Dopamine
antagonists reduce
effects of both drugs
on GIT.

CCNS: dizziness,
anaphylactic reactions,
anaphylactic shock,
increased ICP,
disorientation,
restlessness,
irritability, dizziness,
drowsiness, headache,
confusion,
hallucination, delirium,
impaired memory
CV: hypotension,
tachycardia,
palpitations, flushing
GI: Dry mouth,
constipation, nausea,
epigastric distress
DERM: flushing,
dyshidrosis
GU: Urinary
retention, urinary
hesitancy
Resp: dyspnea,
bronchial plugging,
depressed respiration
EENT: mydriasis,
dilated pupils, blurred
vision, photopobia,
increased intraocular
pressure, difficulty of
swallowing.

Before:
1.Check doctors
order
2.Assess whether
patient is
contraindicated to
the drug
3.Prepare
medication ahead
of time
4.Dilute with 20cc
compatible
intravenous fluid
5.Verify drug, dose,
route, timing and
pt.s identity
6.Explain procedure
to pt.
During:
1.Administer on
right route
2.Observe aseptic
techniques
3.Ensure patency
4.Introduce
medication slowly
After:
1.Educate pt. about
possible adverse
reactions
2.Instruct patient to
report any
unusual reaction
3.Chart accordingly
4.Institute safety
precautions
5.Ensure adequate
ventilation