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MIRACLE FRUIT TO FIGHT AGEING!

Pomegranates have
been known for their
vital vitamins and
health powerhouse.
And they can fight
against aging too,
says Patrick
Aebischer.

"It's

a completely natural substance, and its effect is powerful and


measurable," says
Patrick Aebischer, President, Ecole Polytechnique Federale de Lausanne -- a
research institute in Switzerland.
And this natural substance is none other than POMEGRENATE. Yes this luscious
red fruit which is already known for its antiviral and antitumor properties can also
help in fight against ageing.
Pomegranates are said to be good sources of vitamins, since it includes vitamin A, C
and E, as well as folic acid. This fruit consists of three times as many antioxidants as
both wine or green tea. It is said to be health powerhouse.
Researchers have found that a molecule produced by our body when we consume
pomegranates, transformed by microbes in the gut, may enable muscle cells to
protect themselves against one of the major causes of ageing. The findings showed
that when we drink the pomegranate juice, our body produces Urolithin A -- a
molecule. When this molecule gets transformed by microbes in the gut, it enables
the muscle cells to protect themselves against ageing and also increases the muscle
mass. As we age, our cell increasingly struggle to recycle the mitochondria -- the
powerhouse of the cells -- and are no longer able to carry out their vital function and
thus gets accumulated in the cell. This degradation affects the health of many
tissues, including muscles, which gradually weaken over the years and leads to agerelated various diseases.
"It is the only known molecule that can relaunch the mitochondrial clean-up process,
otherwise known as mitophagy. It is a completely natural substance, and its effect is
powerful and measurable," said Patrick Aebischer from EPFL.

Researchers started out by testing their hypothesis on the usual suspect: the
nematode C elegans. It is a favourite test subject among ageing experts, because
after just 8-10 days it is already considered elderly, they said. The lifespan of worms
exposed to urolithin A increased by more than 45 per cent compared with the control
group, they said.
The fruit does not itself contain the 'miracle molecule', but rather its precursor.
That molecule is converted into urolithin A by the microbes that inhabit the intestine,
researchers said.
Because of this, the amount of urolithin A produced can vary widely, depending on
the species of animal and the flora present in the gut micro biome.
Some individuals do not produce any at all, they said.
Researchers are currently doing clinical trials on human to find more and test the
molecule in humans.
The findings were published in journal Nature Medicine under trials in human.

- Shweta Giri

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