o Side effects:
Dry mouth
Nausea
Increased suicidal ideations
o Precautions:
Risk for suicide by overdose
Risk for heart problems
MAO inhibitors: Side effects and dietary precautions
o Side effects:
Interaction with Tyramine, an amino acid that stimulate the release of
epinephrine and norepinephrine
Urinary retention
Hypertensive crisis marked by sudden severe increase in blood pressure
which exceeds 200/130
Severe headaches
Cardiac arrythmias
Nose bleeds
Muscle twitches (can lead to convulsions as well as a coma)
o Dietary precautions:
Beer and red wine
Chocolate
Pepperoni/salami
Aged cheeses
Sour cream
Broad beans
Avocados
Yogurt
Bananas
Length of time to see effectiveness of antidepressants
Precautions when discontinuing antidepressants
All interventions in major depressive disorder
o Monitor intake of food and fluids
Client will eat 50% of meals within 2 days
Loss of appetite = priority focus
o Weigh daily
o Maintain schedule of regular activities
o Remove potentially harmful articles
o Contract with client to report suicidal feelings
o Assist with dressing, feeding, and hygiene
o Encourage verbalization of feelings
o Accept clients negativity without judging
o Dont attempt to cheer the client up, because its not effective and may make the
client worse
This is due to the fact that they cant meet the expectations
Results in further depression and guilt
o Give appropriate positive feedback to increase self esteem
o Avoid excessive cheerfulness
o Medical management:
Electroconvulsive therapy
Administration of antidepressants as ordered
o Limit group activities until patient can respond appropriately
Too challenging and individual doesnt have enough energy
Facilitate completion of one task at a time; form a small group
Etiology and biochemistry of mood disorders
o Biochemical imbalances
o Serotonin deficiency
o Neurotransmitter deficiencies
Symptoms of major depression and biopolar disorder
o Hyperactivity that leads to physical exhaustion
o Flamboyant dress and makeup; excessive spending
o Sexual acting out and impulsive behavior
o Appearance of an inflated self esteem
o Flight of ideas with the inability to finish one thought before jumping to another
o Loud, domineering, and manipulative
o High degree of distractibility
o Dehydration and nutritional deficits
o Delusions of grandeur
o Hostility and aggression
o Decreased sleep
Lithium administration levels
o Initial dose = 600 mg TID for maintenance of serum level (1.0-1.5 mEq/L)
Take serum levels biweekly
o Maintenance dose = 300 mg TID/QID to maintain serum levels between 0.4-1.0
mEq/L
Check blood levels monthly
o Toxicity occurs with serum leels higher than 2.0 mEq
Signs of lithium toxicity
o Tremors
o Nausea
o Vomiting
o Thirst
o Polyuria
o Diarrhea
o Confusion
o Coma
o Seizure
o Cardiac arrest
Use of anticonvulsants in mood disorders
Educational interventions in medication noncompliance
Signs and symptoms of mania
o Elation and aggression
Signs of impending suicide
o Changes in personal habits
o Changes in personality
o Use of alcohol and other drugs with increased intake
o Bodily complaints and self-deprecating comments
o Giving away personal belongings
o Making out wills and putting things in order
o Decreased interpersonal interaction
High risk time for suicide attempt
o Within the first 2 years after an attempt (60-70% try again)
o Elderly
o Third leading cause of death in teens
o When patient is getting better and the depression is lifting
Assessment for suicide
o Usually preceded by a crisis or patient is morbidly depressed
o Thoughts, threats, attempts are a cry for help
o Risk taking behaviors in adolescents
o 75-80% give clues before committing suicide
o Hopelessness highly correlates with suicide
o Alcohol and drugs and poor impulse control are closely associated with suicide
o Ask directly if client has thoughts of hurting self
o Ask if there is a plan to hurt self
o Determine lethality of plan
The more lethal the plan, the more likely it is that the person will follow
through with the attempt
o Determine if client has the means to hurt self
o Assess ability for no harm contract and ability to communicate when suicidal
feelings increase
SCHIZOPHRENIA
Interpersonal theory
Results from intense, unrelieved anxiety in interpersonal
relationships
Psychoanalytical theory
Freud blamed it on the motherly figure
Hallmark = Break from reality
o Biochemistry:
Genetic difference in nervous system
Altered brain circuits related to cerebral abnormalities
Overactive basal ganglia
Imbalance between dopamine and seratonin, especially an excess of
dopamine
Define: idea of reference, delusion, hallucination, signs of hallucinations, grandiosity,
echolalia, word salad, loose associations, waxy flexibility
o Idea of reference
o Delusion: False belief absent of external stimuli; inconsistent with individuals
own knowledge and experiences; disorder of thought content with presence of
strong beliefs that are misinterpretations of reality
o Hallucination: false sensory perceptions involving all senses, no presence of
external stimulus, and hearing voices making commands or insults
o Signs of hallucinations
Laughing/talking to no one
Nodding/tilting head as if listening
Darting eyes/mumbling
Ask: Are you hearing voices right now?
o Grandiosity
o Echolalia: A parrot-like repetition of speech heard from others
o Word salad
o Loose associations: jumbled illogical thinking manifested in loosely associated
speech
o Waxy flexibility: Symptomatic of excessive negativism, stand in one position for
hours on end, and limb/body will remain passively in position in which it is
placed
Positive and negative symptoms of schizophrenia
o Positive (hard):
Hallucination
Delusions
Disorganized thinking
Paranoia
Withdrawal from reality
o Negative:
Lack of motivation
Impaired social interaction
Anorexia nervosa: What is it? What are the signs and symptoms? What are the primary
problems? What personality traits are present? What assessment and intervention
methods are involved?
Bulimia nervosa: What is it? What are the signs and symptoms? What are the primary
problems? What personality traits are present? What assessment and intervention
methods are involved?
COGNITIVE DISORDERS
Tofranil
Nardil
Elavil
Lithium
Tegratol
Thorazine
Clozaril
THERAPEUTIC COMMUNICATION/RESPONSES