Chapter 04
Cellular Metabolism
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5. Catabolism refers to
A. chemical reactions that acquire energy.
B. chemical reactions that release energy.
C. breakdown of large molecules.
D. the formation of genetic material.
E. build up of ADP into ATP.
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12. An enzyme is
A. a molecule, usually a protein, that speeds the rate of a biochemical reaction by lowering the
activation energy.
B. the genetic material.
C. a protein that promotes metabolic reactions by slowing reactions that are too fast.
D. usually a vitamin.
E. a type of protein used to smoothen aged and wrinkled skin.
Difficulty Level: Remember/Understand
Learning Outcome: 04.03
Topic: Cells
4-5
15. Which of the following best describes the interaction between an enzyme and its
substrate?
A. The enzyme surrounds and completely contains the substrate.
B. The substrate surrounds and completely contains the enzyme.
C. The enzyme temporarily deactivates the substrate.
D. Part of the enzyme temporarily binds part of the substrate molecule.
E. When enzyme meets substrate, an explosion may occur.
Difficulty Level: Evaluate/Create
Learning Outcome: 04.03
Topic: Cells
17. An important mechanism that controls metabolic pathways under physiological conditions
is
A. positive feedback.
B. substrate concentration.
C. negative feedback.
D. genetic control.
E. signal transduction.
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18. Three factors that increase the rates of enzyme-controlled reactions are the
A. number of enzyme molecules, number of substrate molecules, and efficiency of the
enzyme.
B. temperature of the reaction, number of H2O molecules, and bond strength.
C. number of enzyme and substrate molecules formed and strength of the enzyme.
D. size of the enzyme compared to the substrate, the number of active sites, and the ratio of
enzyme to substrate molecules.
E. temperature of the reaction, the time that the enzyme stays bonded to the substrate, and the
shape of the substrate
Difficulty Level: Evaluate/Create
Learning Outcome: 04.03
Topic: Cells
4-7
21. A molecule that carries energy in a form the cell can use is
A. glucose.
B. glycogen.
C. vitamin C.
D. ATP.
E. DNA.
Difficulty Level: Remember/Understand
Learning Outcome: 04.04
Topic: Cells
4-8
25. Oxidation during cellular respiration differs from burning in that respiration
A. doesn't use enzymes to lower the activation energy.
B. requires a relatively large amount of energy to start the process.
C. uses enzymes to lower the activation energy.
D. releases more energy as heat and light.
E. uses enzymes to raise the activation energy.
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27. Which of the following substances increases in abundance during cellular respiration?
A. Oxygen
B. Glucose
C. ATP
D. Glycogen
E. DNA
Difficulty Level: Remember/Understand
Learning Outcome: 04.05
Topic: Cells
28. A molecule that is common to carbohydrate and lipid metabolic pathways and connects
these two pathways metabolically is
A. glucose.
B. pyruvic acid.
C. acetyl coenzyme A.
D. glycogen.
E. fructose.
29. A glucose molecule is broken down into two pyruvic acid molecules in
A. glycolysis.
B. the citric acid cycle.
C. gluconeogenesis
D. the electron transport system.
E. acetyl CoA formation
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32. Anaerobic respiration occurs in _____, whereas aerobic respiration occurs in ______.
A. mitochondria; cytoplasm with O2 required
B. cytoplasm without O2 required; cytoplasm with CO2 required
C. mitochondria without O2 required; mitochondria with O2 required
D. cytoplasm without O2 required; mitochondria with O2 required
E. mitochondria with O2 required; chloroplasts without O2 required
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38. If one strand of DNA has the sequence TCAGGCTATTCCCG, then the complementary
sequence of the other strand is
A. AGUCCGAUAAGGGC.
B. AGTCCGATAAGGGC.
C. TCAGGCTATTCCCG.
D. UCAGGCUAUUCCCG.
E. GCCCTTATCGGACT
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41. How many codons specify the twenty types of amino acids?
A. 61
B. 23
C. 46
D. 4
E. 3
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44. Which of the nitrogenous bases is part of DNA but not RNA?
A. Adenine
B. Thymine
C. Guanine
D. Cytosine
E. Uracil
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45. Which of the nitrogenous bases is part of RNA but not DNA?
A. Cytosine
B. Thymine
C. Guanine
D. Uracil
E. Adenine
Difficulty Level: Remember/Understand
Learning Outcome: 04.06
Topic: Cells
46. DNA, RNA, and protein molecules can carry information because
A. they are organic.
B. they are large.
C. they consist of sequences of building blocks.
D. they release energy when they are broken down.
E. they are located in the nucleus.
47. A sequence of DNA 333 nucleotides long that is part of a gene encodes ___ amino acids.
A. 333
B. 111
C. 999
D. 444
E. can't tell from given information
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52. Which DNA sequence can encode the amino acid sequence ile-asp-ser-cys-his-tyr?
A. TAGCTGTCAACAGTGATA
B. TAACTGTCGACGGTGATG
C. TAACTAAGTACGGTGATG
D. GTAGTGGCATGAATCAAT
E. all of the answer choices are correct
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59. A mutation is
A. a change in a DNA sequence in less than 1% of a population that affects anatomy and/or
physiology.
B. a common genetic variant.
C. a change in the genetic code.
D. always harmful to health.
E. an inherited disease.
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66. MicroRNAs
A. are 21 or 22 bases long.
B. control gene expression.
C. are noncoding RNAs.
D. regulate transcription of several genes.
E. are all of the above
Boxed Reading: From Science to Technology 4.3
Difficulty Level: Remember/Understand
Topic: Cells
69. Proteins are critical to metabolism because all proteins are enzymes.
FALSE
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73. In adipose tissue, fat molecules form when fatty acid molecules and glycerol join by
hydrolysis.
FALSE
74. A different enzyme may catalyze the formation and the breakdown of the same molecule.
TRUE
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77. An active site is the part of a substrate molecule that binds an enzyme.
FALSE
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84. During the anaerobic phase of respiration, pyruvic acid reacts to form glucose.
FALSE
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86. For each citric acid molecule that enters the citric acid cycle, 2 ATPs, 16 H atoms, and 4
CO2 molecules are produced.
FALSE
87. The electron transport chain is a series of enzyme complexes that pass electrons, releasing
energy that is used to phosphorylate ADP to ATP on the inner mitochondrial membrane.
TRUE
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90. Genetic information is contained in protein molecules and is passed from one parent to
another.
FALSE
Difficulty Level: Evaluate/Create
Learning Outcome: 04.06
Topic: Cells
91. The portion of a DNA molecule that contains the genetic information for making a protein
is called a gene.
TRUE
92. A DNA molecule is a double helix in which A pairs with C and T pairs with G.
FALSE
94. In DNA replication, the two halves of the double helix part and enzymes place A, C, G,
and U nucleotides opposite their complements, forming two double helices from one.
FALSE
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95. A DNA strand of ACTTCGCATG, when replicated, would yield a strand of the same
sequence.
FALSE
Difficulty Level: Apply/Analyze
Learning Outcome: 04.06
Topic: Cells
97. The genetic code is the correspondence between DNA sequence and amino acid sequence
of a protein.
TRUE
98. DNA and RNA differ in strandedness, type of sugar, and types of nitrogenous bases.
TRUE
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103. The part of the tRNA that binds mRNA is the anticodon.
TRUE
104. A single nucleotide polymorphism is a very rare genetic variant that affects health.
FALSE
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105. A mutation that changes a CGC codon to CGA would not affect health because the
encoded amino acid is unchanged.
TRUE
Difficulty Level: Apply/Analyze
Learning Outcome: 04.07
Topic: Cells
108. A type of genetic change is certain sequences present in different numbers of copies in
different individuals.
TRUE
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112. The process that extracts energy from glucose and makes it available is _______
________.
cellular respiration
113. Anaerobic and aerobic respiration begin with _______, in which glucose is broken
down.
glycolysis
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114. The correspondence between a unit of DNA information and an amino acid is the _____
______.
genetic code
Difficulty Level: Remember/Understand
Learning Outcome: 04.06
Topic: Cells
116. Adenine and guanine are ________ and cytosine and thymine are ______.
purines; pyrimidines
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120. If the DNA triplet UGU mutates to CGU, then the encoded amino acid changes from
_____ to _____.
cysteine; arginine
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