2010
3,082,113
Tilapia (D)
469,173
Shrimp (E)
352,600
Milkfish (D)
483,948
374,112
Clariid Catfish(D)
273,554
144,056
74,912
Grouper (E)
18,805
Barramundi (E)
Other
Total
1,776
203,015
5,478,064
Crustacean Waste
Protein
Calcium Carbonate
Carotenoids
Polysaccharides- Chitin > Chitosan
Chitin Sources
Crawfish/Crabs
Chitin
Protein
CaCO3
Lipids
25-30%
15%
55%
2-5%
Shrimp
30-40%
35%
30%
5-10%
Fungi
15-40%
5-10%
Glycans
5-10%
Chitin
Naturally occurring polysaccharide, second most
abundant in nature next to cellulose
Chitin and its deacetylated derivative chitosan are
exceptionally useful polymers
They are biodegradable, non-toxic and biocompatible
making them useful in a range of applications
CHITIN
POLIMER BETA GLUKOSAMIN
DENGAN IKATAN BETA 1-4
GLIKOSIDIK
CHITOSAN
PRODUK DEASETILASI CHITIN
STRUKTUR MOLEKUL
CHITIN
STRUKTUR MOLEKUL
CHITIN
STRUKTUR MOLEKUL
CHITIN
KERANGKA MOLEKUL
CHITIN
STRUKTUR 3 DIMENSI
MOLEKUL CHITIN
Chitin Uses
Agriculture-fertilizer to improve crops
Medicine-Wound and burn treatmentincreases healing time
PERBANDINGAN STRUKTUR
MOLEKUL
CHITIN-SELULOSA
PERUBAHAN
CHITIN MENJADI CHITOSAN
PERUBAHAN
CHITIN MENJADI CHITOSAN
PERUBAHAN CHITIN
MENJADI GLUKOSAMIN
Produk Chitosan
FARMAKOLOGI CHITOSAN
MENURUNKAN ABSORPSI LEMAK
ANTI OBESITAS
MENURUNKAN KADAR
KOLESTEROL DARAH
MEKANISME AKTIVITAS
CHITOSAN
MEKANISME AKTIVITAS
CHITOSAN
MEKANISME AKTIVITAS
CHITOSAN
CHITIN MANUFACTURING
CHITIN CHITOSAN
MANUFACTURING
PEMBUATAN CHITOSAN
Isolation of Chitin/Chitosan
HO
O
NH-C-CH3
O
NH2
Chitosan
Chitin
CH2OH
O
O
O
CH2OH
Chitin +CaCO3
30% HCl ( CaCO3)
HO
NH2
10% NaOH,
24 hr, RT
Proteins, Lipids,
Pigments, Hemicelluloses
Solubles
Insolubles
Acetic
acid
Chitin/glucan
50:50
Mixture of glucanases
KytoZyme Plant
producing 100 tons/year
to open in 2005
pH = 5.5, 4 days, 37 C
Chitosan
Chitin
Sources of Chitin/Chitosan
USA
Company
Location
Products
Vanson
Halosource
Chitin/ Chitosan
N-Haloamines
AIDP, Inc.
Aminoacids
Herbal extracts
Chitin/ Chitosan
Glucosamine
Speciality
carbohydrates
Chitin/ Chitosan
V-Labs, Inc
N-Carboxymethyl
chitosan (NCMC)
N, O-Carboxymethyl
chitosan (NOCC)
Sources of Chitin/Chitosan
Company
Randburg
Primex
Genis
KitoZyme
Kraeber Gmbh
Europe
Location
Products
Oskarsgata 7
IS - 580 Siglufjordur
Iceland
Haugesund, Norway
Rue Haute Claire 4
B4040 Herstal
Belgium
Chitosans
Marine proteins
From Shrimp
Waldhofstrasse 14
25474 Ellerbek
Germany
Biopharmaceutical raw
materials
Chitin/Chitosan
Chitin-glucan
Chitosan-glucan
Chitin/Chitosan
From Aspergillis sp
Sources of Chitin/Chitosan
Asia
Company
Location
Products
5 Sheffield Crescent
Bishopdale
P.O. Box 20-028
Christchurch, NZ
b-chitin from
squid pen
Meron Biopolymers
Yuhuan Ocean
Biochemical Co., Ltd
Glucosamine
Chitin/Chitosan
Jinke Chitosan
Chitin/Chitosan
Literatur Kitin-Kitosan
PENGGUNAAN CHITOSAN
PENGGUNAAN CHITOSAN
Agrochemicals
Anti-nemotode Treatment -- Chitin-Protein
complex
Preservative Coating on Produce
Animal Feed Additives
Fertilizer complete with Trace Minerals
(Dried Shrimp Shells @ $100 per ton)
Biocompatibility
Biodegradable to normal metabolites
Hemostatic Bacteriostatic
Spermicidal Anti-cancer
Anticholesteremic
Fungistatic
Foods:
Dietary fiber, emulsifier, inert ingredient
carrier
Anti-cholesterol food additive ?
Clarification of Beverages and Fruit
Juices
Removal of Dyes or Color Stabilization
Fat BlockerFat Zapper!
CHITIN/CHITOSAN LIMITATIONS
1. High Isolation Costs
Dependent on NaOH price fluctuations
4.