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Newdrugswitnessupsurgeindiabetesmarket
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NarayanKulkarni,July24,2016

FollowingthelaunchofTenepan,usedfor
treatingtype2diabetesmellitusbyPanacea
BioteconJuly28,SanofiSynthelaboIndia,in
lessthanamonth,announcedthelaunchofits
twodrugsLyxumia(lixisenatide)and
Zemiglo(gemigliptin)fortype2diabetes
patientsinIndia.

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AnkleBuckleClosure Lyxumiaisaoncedaily,noninsulininjectabledrugandZemigloisaoncedaily,
FlatSandalOnlineIndia oraltablet.Boththeseareprescriptiondrugsandaretobetakenonlywhen

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prescribedbythedoctor.
PanaceaBiotecduringthelaunchnotedthatTenepanaimstoimprove
accessibilityofdiabetestreatmentatanaffordablecostanditintendstoreachout
topatientswiththelatesttherapeutictreatment.
InMarchthisyear,SunPharma,oneoftheleadingpharmacompaniesinIndia,
joinedhandswiththeIndiansubsidiaryofAngloSwedishpharmafirmAstraZeneca
forthedistributionoflattersForxiga,aninnovativetype2diabetesdrug,inthe
country.Forxiga(dapagliflozin)isAstraZenecaIndiasleadingdiabetesdrug.Under
theagreement,SunPharmawillpromoteanddistributedapagliflozinunderthe
brandnameOxra.AstraZenecaIndiamarketsdapagliflozinunderthebrandname
Forxigaandunderthetermsoftheagreement,bothcompanieswillpromote,
marketanddistributedapagliflozininIndiaunderdifferentbrandnames.
AstraZenecawillretaintheintellectualpropertyrightstodapagliflozin.
Duringthesameperiod,USpharmamajorEliLillytoohaslaunchedonceaweek
diabetestreatmentdrugunderthebrandnameTrulicity,inthecountry.The
medicineisaninjectablemedicationandbelongstoaclasscalledGLP1
(Glucagonlikepeptide1)receptoragonists.Trulicitycomesinasingledosepen
andisdesignedtoimprovethebloodsugarcontrolinadultswithtype2diabetes.
Alltheseproductlaunchesbothbylocalandmultinationalcompanieswere
targetedtowardstype2diabetes.
Whatistype2diabetes?Accordingtotheworldhealthorganisation(WHO),type2
diabetes(formerlycallednoninsulindependentoradultonsetdiabetes)iscaused
bythebodysineffectiveuseofinsulin.Itoftenresultsfromexcessbodyweight
andphysicalinactivity.Inadditiontotype2diabetes,therearetwootherformsof
diabetes:type1andgestationaldiabetes.
AccordingtoWHOreport,thereare69.1millioncasesofdiabetesin2015inIndia
and415millionpeopleworldwide.Italsopointedthatthenumberofdeathsin
adultsduetodiabetesis1.03millionandnumberofcasesofdiabetesinadults
thatareundiagnosedis36.06million.Thereportobservedthatby2035,itis
estimatedthat123.5millionpeoplewillhavediabetes.Thealarmingfactisthat
almosthalfoftheexistingdiabetespatientsareunawarethattheyhavediabetes.
Diabetesconsumesbetween5%and25%oftheincomeofanaverageIndian
family,accordingtoareportpublishedinJournalofDiabetology,whichtranslates
to$2.2billionayearondiabetescareandtreatment.Manypatientsareunawareof
treatmentexpensesandarenotabletoplanthebudget.Indevelopedcountries,

diabetesaloneclaimsonaveragearound8%oftotalhealthcarebudgets.Theper
capitaexpenditureonhealthcareinIndiaisonly6.4%ofaverageworldspending.
Thedirecthealthcarecostofdiabetesisestimatedtobeatleast$153billion
annuallyforpeopleinthe20to79agegroup.

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SharingdetailsaboutantidiabetesdrugsmarketinIndia,HariNatarajan,vice
presidentBusinessIntelligenceIndia&GlobalAudit,AIOCDPharmasofttech
AWACS,saidthatthemarketisvaluedatRs8,346croregrowingat19%ason
MAT(movingannualtotal)June2016.

http://www.deccanherald.com/content/559745/drugswitnessupsurgediabetesmarket.html

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10/6/2016

Newdrugswitnessupsurgeindiabetesmarket
Themarketishighlyfragmentedwitharound50activeplayers.Thetopfive
playerscumulativelyaccountfor50%ofthismarket.Abbottisleadingthetableof
thetop10playersinthisspacewithamarketshareof14.79%,followedbyUSV
with11.93%andSunPharmawith9.44%.IndianplayerssuchasLupin,Microand
MankindPharmaceuticalsarecompetingwiththemultinationalcompaniesnamely
Sanofi,MSD,NovartisandEliLillyandCompany.
Toprovideanalternativeandaffordabledrugswithoutanysideeffectstopeople
sufferingfromtype2diabetes,IndianscientistsworkingatthetwoCouncilof
ScientificandIndustrialResearch(CSIR)laboratories,NationalBotanical
ResearchInstitute(NBRI)andCentralInstituteforMedicinalandAromaticPlant
(CIMAP)havedevelopedanantidiabetesherbaldrugBGR34.Acomboof
naturalingredientsfromplants,thedrugisbasedonayurvedaanditcontrolstype
2diabetes.

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NewDelhibasedAimilPharmaceuticalshasreceivedthetechnologyfromNBRI
forcommercialproductionandmarketing.Thecompanynotedthatitwillofferthe
drugintheformoftabletsandmaypriceRs500for100tablets.
Theprevalenceoftype2diabetesisrisingrapidlyworldwide.Oneofthelargest
absoluteincreasesisexpectedtooccurinIndia,withtheInternationalDiabetes
Federation(IDF)estimatingthatIndiaalonewillhave100millionpeoplewith
diabetesby2030.About90%ofthesewillhavetype2diabetes.
Overall,thenumberofpeoplelivingwithdiabeteshasalmostquadrupledsince
1980to422millionadults,withmostlivingindevelopingcountries.Takingserious
noteofthesituation,WHOcallsforglobalactiontohaltriseinandimprovecare
forpeoplewithdiabetes.Itcameupwithsuggestionsastohowtoprevent,
diagnoseandtreatdiabetes.Itobservedthatahealthydiet,regularphysical
activity,maintaininganormalbodyweightandavoidingtobaccousearewaysto
preventordelaytheonsetoftype2diabetes.Diabetescanbetreatedandits
consequencesavoidedordelayedwithdiet,physicalactivity,medicationand
regularscreeningandtreatmentforcomplications.

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