risk
especially
to
encapsulated
bacteria
because
of
autosplenectomy.
Hepatobiliary
complications:
Pigemented gallstones
due
to
increased
bilirubin from hemolysis.
Biliary sludge
Biliary cholic
Acute cholecystitis
Acute choledocolithiasis
Acute cholangitis
Acute
hepatic
sequestration
Acute
intrahepatic
cholestasis
Pain
from
vasoocclusion
Acute
chest
syndrome :
Presents with signs and
sx of lower resp tract
infection and has a new
pulmonary infiltrate on
radiograph .
Splenic
Prevention:
Immunizations and ppx
antibotics until 5 years
old.
sequestration:
Stroke:
-Kids ischemic stroke
-Adults
hemorrhagic
stroke
Multisystem
organ
failure.
Workup: CT
Comprehensive
metabolic panel . CBC
with diff.
1) splenic sequestration
with hypovolemia:
Immediate IV hydration
2) Splenic sequestration
with severe anemia.
Transfuse to raise Hg
but slowly because can
cause over transfusion
Tx: exchange
transfusion.
Tx: exchange
transfusion.
Presents
are
rapid
deterioration,
fever,
drop
in
Hg,
and
encephalopathy