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POINTS ABOUT

DRUGS
medpgnotes

POINTS ABOUT DRUGS

Contents
ANTICHOLINESTERASE .................................................................................................................................................................................................................................. 2
AUTACOIDS .......................................................................................................................................................................................................................................................... 2
BETA BLOCKERS ................................................................................................................................................................................................................................................ 2
BISPHOSPHONATES ......................................................................................................................................................................................................................................... 2
CATARACT NUGGETS....................................................................................................................................................................................................................................... 3
CONDITION AND SPECIFIC DRUG ............................................................................................................................................................................................................... 4
CONDITION AND SPECIFIC SURGERY ....................................................................................................................................................................................................... 5
DIABETES NUGGETS ........................................................................................................................................................................................................................................ 6
DIFFERENT USAGE OF DRUGS ..................................................................................................................................................................................................................... 7
DRUG OF CHOICE ............................................................................................................................................................................................................................................... 7
DRUG KINETICS............................................................................................................................................................................................................................................... 11
FEW DRUG INTERACTIONS ........................................................................................................................................................................................................................ 11
MECHANISM OF ACTION OF DRUGS ....................................................................................................................................................................................................... 12
MONOCLONAL ANTIBODIES ...................................................................................................................................................................................................................... 19
NITRATES NUGGET ....................................................................................................................................................................................................................................... 19
OPIOID NUGGET .............................................................................................................................................................................................................................................. 20
PRODRUGS ........................................................................................................................................................................................................................................................ 20
SAFEST DRUGS IN PREGNANCY NUGGET............................................................................................................................................................................................. 21
STEROID DRUGS ............................................................................................................................................................................................................................................. 21
TREATMENT OF CHOICE ............................................................................................................................................................................................................................. 22

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ANTICHOLINESTERASE

POINTS ABOUT DRUGS

ANTICHOLINESTERASE
Naturally occurring Anticholinesterase
Lipid Soluble Anticholinesterase
Blood brain barrier crossing Anticholinesterase
Anticholinesterase used in Myasthenia Gravis
Anticholinesterase used for Diagnosis of Mtasthenia
Gravis
Anticancer showing Anticholinesterase Property

Physostigmine
Neostigmine/Pyridostigmine
Edrophonium
Irinotecan

AUTACOIDS
FUNCTION
Most Important chemical elevating Hypothalamic
setpoint
Vasoconstrictor
Prostaglandins causing Renal Vasodilataion
Vasodilatation in blood vessels
Platelet Aggregation
Inhibition of Platelet aggregation
Chemotactic
Bronchoconstrictor
Slow reacting substance of anaphylaxis(SRSA)

AUTAOIDS
PGE2
PGF2
PGI2,PGE2
PGI2,PGE2,PGF2
TXA2
PGI2
LTB4
LTC4
LTD4
LTE4

BETA BLOCKERS
Most Cardioselective
Vasodilator Property
K+ Blocking Property
K+ Opening Property
Selective 2 blocker
Non Catecholamine acting selectively on

Nebivolol
Sotalol
Tilsolol
Butoxamine
Prenalterenol

BISPHOSPHONATES
st

1 Bisphosphonate Approved
Treatment of Postmenopausal Osteoporosis
Prevention of Steroid Induced Osteoporosis
Unique Administration Technique
Once Yearly i.v/Once Monthly Oral
Most Potent Drug for Treatment & Prevention of
Osteoporosis

Etindronate
Alendronate
Risendronate
Risendronate
Zolendronate
Idandronate
Bisphosphonates

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CATARACT NUGGETS

POINTS ABOUT DRUGS

CATARACT NUGGETS
Anterior Polar
Anterior Capsular
Anterior Subscapular
Posterior Polar
Posterior Capsular
Posterior Subcapsular

Perforation of corneal ulcer


Vossious ring
Glaucoma
Mittendorf dot

MC cause of blindness in India


MC cause of blindness in Adults
MC cause of blindness in children
MC cause of cataract
MC Type of Congenital Cataract
MC Health Disorder among Geriatrics
MC visually significant Congenital cataract
Lens changes in Anterior Uveitis
Second Sight
Fluctuation of Refractory Error
Complication of Intumescent Cataract
Complication of Morgagnian cataract
Complication of Hypermature Sclerotic Cataract

Cataract
Cataract
Keratomalacia
Age Related
Punctate cataract
Visual Impairment/Cataract
Lamellar/Zonular cataract
Complicated Cataract with Posterior Capsular Opacities
Nuclear Cataract
Diabetic Cataract
Phacomorphic Glaucoma
Phacolytic Glaucoma
Subluxation/Dislocation of Lens
Phacoanaphylactic Uveitis
Galactitiol
Sorbitol
Oil Drop Cataract
Cataract

Steroid

Cataract in Galactosemia is due to accumulation of


Cataract in Diabetes due to accumulation of
Galactosemia
MC Ocular Complication of Systemic Steroid

SPECIFIC CATARACT
Snow Flake Cataract
Sunflower Cataract

Vossious ring on anterior surface of lens


Rossette Shaped Cataract
Christmas Tree cataract
Oil drop Cataract
Morgagnian Cataract
Rainbow cataract
Breadcrumb Cataract
Polychromatic Lusture
Snow Blindness
Glass Blowers Cataract

Diabetes Mellitus
Wilsons disease
Chalcosis
Penetrating trauma
Blunt Trauma
Myotonica Dystrophica
Galactosemia
Hypermature Senile Cataract
Complicated Cataract
Ultraviolet
Infrared

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