Bohr effect (medical or scientific explanation)

Christian Bohr stated that at lower pH (more acidic environment, e.g.,

in tissues), hemoglobin would bind to oxygen with less affinity. Since
carbon dioxide is in direct equilibrium with the concentration of
protons in the blood, increasing blood carbon dioxide content,
according to the Bohr effect, causes a decrease in pH, which leads to a
decrease in affinity for oxygen by hemoglobin (and easier oxygen
release in capillaries or
tissues).
The description of the
Bohr effect, which is a
physiological law, can be
found in nearly all
physiological textbooks.
Modern studies related to
the Bohr effect are
devoted to more
advanced topics (see the
titles of studies for
modern research below).
It is the central
proposition of the Bohr
effect that oxygen affinity
to hemoglobin depends
on absolute CO2 concentrations and reduced CO2 values decrease
oxygen delivery to body cells.
http://www.normalbreathing.com/CO2-bohr-effect.php