Anda di halaman 1dari 34

Absorbansi Generik

Persamaan

Y = 0.0491x + 0.025
0.0491

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

0.025

Waktu ( Menit)
20
3.4009
3.4479
3.3794
3.7638
3.6210
3.3794

30
3.7084
3.7870
3.7707
3.9769
4.2610
3.7707

45
3.8341
3.8106
3.8381
3.7086
3.6797
3.8381

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
10
15
20
64.257
65.473
68.756
64.037
64.906
69.713
64.039
64.756
68.318
101.723
71.835
76.147
80.157
96.043
73.238
64.039
64.756
68.318

30
75.018
76.619
76.287
80.487
86.273
76.287

45
77.578
77.100
77.660
75.022
74.434
77.660

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
10
15
20
57.831
59.247
62.209
57.633
58.736
63.068
57.635
58.600
61.812
91.551
65.160
68.894
72.141
86.839
66.397
57.635
58.600
61.812

30
67.862
69.308
69.002
72.821
78.014
69.002

45
70.198
69.775
70.277
67.925
67.424
70.277

10
3.1800
3.1692
3.1693
5.0196
3.9607
3.1693

15
3.2397
3.2119
3.2045
3.5521
4.7407
3.2045

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6
RATA2

10
64.257
64.037
64.039
101.723
80.157
64.039

Konsentrasi Terkoreksi
Waktu ( Menit)
15
20
65.829
69.121
65.262
70.075
65.111
68.679
72.400
76.549
96.488
73.774
65.111
68.679

30
75.402
77.008
76.669
80.912
86.683
76.669

45
77.997
77.528
78.086
75.472
74.915
78.086

10
38.554
38.422
38.423
61.034
48.094
38.423
43.825

Persentase Terdisolusi (%)


Waktu ( Menit)
15
20
39.498
41.473
39.157
42.045
39.067
41.208
43.440
45.929
57.893
44.265
39.067
41.208
43.020
42.688

30
45.241
46.205
46.001
48.547
52.010
46.001
47.334

45
46.798
46.517
46.851
45.283
44.949
46.851
46.208

R rata-rata
43.825
43.020
42.688
47.334

T rata-rata
43.411
44.065
48.386
50.911

Waktu (menit)
10
15
20
30

45

46.208

52.384

Absorbansi Branded
Persamaan

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6
Konsentrasi Tiap
TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

Massa terlarut dalam


Tablet
Brand 1
Brand 2
Brand 3
Brand 4
Brand 5
Brand 6

R-T
0.414
-1.045
-5.698
-3.576

(R-T)^2
0.1715339417047
1.0919273541171
32.4720139461269
12.7894394673820

-6.176
SUM
dibagi 6
1
SQRT
100/sqrt
50 log
F2

38.1378405861695
84.6627552955002
14.1104592159
15.1104592159
3.887217413
25.7253426746
70.5180584248
70.5180584248

Y =0.0441 x + 0.0425
0.0441

0.0425

10

15

Waktu ( Menit)
20

3.2761
3.2095
3.2140
3.2761
3.2095
3.2140

3.2890
3.2303
3.2714
3.2890
3.2303
3.2714

3.5704
3.5409
3.6314
3.5704
3.5409
3.6314

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
10
15
20
73.32426
71.81406
71.9161
73.32426
71.81406
71.9161

73.61678
72.28571
73.21769
73.61678
72.28571
73.21769

79.99773
79.3288
81.38095
79.99773
79.3288
81.38095

30

45

3.7893
3.7264
3.7783
3.7893
3.7264
3.7783

3.8214
3.9491
3.8453
3.8214
3.9491
3.8453

30

45

84.96145
83.53515
84.71202
84.96145
83.53515
84.71202

85.68934
88.58503
86.23129
85.68934
88.58503
86.23129

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
10
15
20
65.992
66.622
72.368
64.633
65.416
71.759
64.724
66.255
73.611
65.992
66.622
72.368
64.633
65.416
71.759
64.724
66.255
73.611

30
76.867
75.580
76.650
76.867
75.580
76.650

45
77.547
80.146
78.034
77.547
80.146
78.034

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6
RATA2

Konsentrasi Te
Wa
10
73.324
71.814
71.916
73.324
71.814
71.916

Persentase Terdi
Wa
10
43.995
43.088
43.150
43.995
43.088
43.150
43.411

Konsentrasi Terkoreksi
Waktu ( Menit)
15
20
74.024
80.409
72.685
79.733
73.617
81.790
74.024
80.409
72.685
79.733
73.617
81.790
Persentase Terdisolusi (%)
Waktu ( Menit)
15
20
44.414
48.245
43.611
47.840
44.170
49.074
44.414
48.245
43.611
47.840
44.170
49.074
44.065
48.386

30
85.408
83.978
85.166
85.408
83.978
85.166

45
86.164
89.052
86.704
86.164
89.052
86.704

30
51.245
50.387
51.100
51.245
50.387
51.100
50.911

45
51.698
53.431
52.023
51.698
53.431
52.023
52.384

Absorbansi Generik
Persamaan

Y = 0.0816 x - 0.0092
0.0092

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

0.0816

Waktu ( Menit)
10
0.811733333
0.697766667
0.421766667
0.6581
0.6025
0.8184

15
1.097366667
1.111466667
0.5777
0.8786
0.8809
1.0531

10
97.101
84.714
54.714
80.402
74.359
97.826

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
15
128.149
129.681
71.663
104.370
104.620
123.337

10
87.391
76.242
49.242
72.362
66.923
88.043

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
15
115.819
117.137
64.770
94.335
94.529
111.492

Y = 0.0816 x - 0.0092

Waktu ( Menit)
20
1.3297
1.1957
1.334933333
1.1519
1.1821
1.1729

30
1.473866667
1.3112
1.341733333
1.2135
1.1639
1.1953

45
1.4352
1.369333333
1.194166667
1.2262
1.1992
1.2268

ntrasi Tiap Tablet (ppm)


Waktu ( Menit)
20
153.402
138.837
153.971
134.076
137.359
136.359

30
169.072
151.391
154.710
140.772
135.380
138.793

45
164.870
157.710
138.670
142.152
139.217
142.217

rlarut dalam 900 mL (mg)


Waktu ( Menit)
20
138.705
125.604
138.934
121.193
124.148
123.342

30
152.936
136.950
140.011
127.368
122.532
125.599

45
149.232
142.700
125.581
128.645
125.976
128.693

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6
RATA2

Konsentrasi Terkoreksi
Waktu ( Menit)
20
154.117
139.560
154.371
134.658
137.942
137.047

10
97.101
84.714
54.714
80.402
74.359
97.826

15
128.688
130.152
71.967
104.816
105.033
123.880

10
58.261
50.828
32.828
48.241
44.615
58.696
48.912

Persentase Terdisolusi (%)


Waktu ( Menit)
15
20
77.213
92.470
78.091
83.736
43.180
92.622
62.890
80.795
63.020
82.765
74.328
82.228
66.454
85.770

Waktu (menit)
10
15
20
30

30
169.929
152.167
155.568
141.520
136.147
139.555

30
101.957
91.300
93.341
84.912
81.688
83.733
89.488

R rata-rata
48.912
66.454
85.770
89.488

45

88.981

45
165.814
158.556
139.535
142.938
139.974
142.993

45
99.488
95.133
83.721
85.763
83.984
85.796
88.981

T rata-rata
56.561
70.765
79.192
80.586

R-T
-7.649
-4.312
6.577
8.902

(R-T)^2
58.5114135712387
18.5907471245993
43.2634455960844
79.2542154514097

78.969

10.012
SUM
dibagi 6
1
SQRT
100/sqrt
50 log
F2

100.2356802500580
299.8555019933900
49.9759169989
50.9759169989
7.1397420821
14.0061081829
57.3158738254
57.3158738254

Absorbansi Branded
Persamaan

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

Tablet
Brand 1
Brand 2
Brand 3
Brand 4
Brand 5
Brand 6

10

15

0.7247
0.602566667
0.8431
0.7920666667
0.8712333333
0.8803333333

10

1.0248
0.8915
0.985933333
1.0454
0.974
1.0702666667

Waktu ( Menit)
20
1.1117
1.134633333
1.142
1.1253666667
1.1261
1.1201

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
15
20

87.64130435
120.2608696
129.7065217
74.36594203
105.7717391
132.1992754
100.5108696
116.0362319
133
94.9637681159
122.5 131.1920289855
103.5688405797 114.7391304348 131.2717391304
104.5579710145 125.2028985507 130.6195652174

10
78.877
66.929
90.460
85.467
93.212
94.102

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
15
20
108.673
117.340
95.566
119.510
104.935
120.283
110.725
118.688
103.783
118.721
113.205
118.187

Menit)
30
1.171633333
1.161466667
1.153633333
1.1401666667
1.1538666667
1.1030666667

45
1.122833333
1.110466667
1.1046
1.1359666667
1.1255666667
1.1349333333

Menit)
30

45

136.2210145
130.9166667
135.115942
129.5724638
134.2644928
128.9347826
132.8007246377 132.3442028986
134.2898550725 131.2137681159
128.768115942 132.231884058

g)
Menit)
30
123.251
122.268
121.506
120.180
121.520
116.548

45
118.510
117.294
116.716
119.777
118.768
119.656

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6
RATA2

10
87.641
74.366
100.511
94.964
103.569
104.558

Konsentrasi Terkoreksi
Waktu ( Meni
15
120.748
106.185
116.595
123.028
115.315
125.784

Persentase Terdisolusi (%)


Waktu ( Meni
10
15
52.585
72.449
44.620
63.711
60.307
69.957
56.978
73.817
62.141
69.189
62.735
75.470
56.561
70.765

nsentrasi Terkoreksi
Waktu ( Menit)
20
130.377
132.789
133.648
131.876
131.912
131.318

30
136.945
135.854
135.007
133.533
135.023
129.498

45
131.677
130.327
129.685
133.086
131.964
132.951

ntase Terdisolusi (%)


Waktu ( Menit)
20
78.226
79.674
80.189
79.125
79.147
78.791
79.192

30
82.167
81.512
81.004
80.120
81.014
77.699
80.586

45
79.006
78.196
77.811
79.852
79.178
79.771
78.969

Absorbansi Generik
Persamaan

Y= 0.0271 x + 0.080
0.0271

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

0.08

Waktu ( Menit)
20
0.34924
0.35107
0.35097
0.34924
0.35107
0.35097

30
0.38531
0.39765
0.38924
0.38531
0.39765
0.38924

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
15
20
94.756
99.351
93.775
100.026
98.439
99.989
94.756
99.351
93.775
100.026
98.439
99.989

30
112.661
117.214
114.111
112.661
117.214
114.111

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
10
15
20
81.585
85.734
89.892
79.506
84.839
90.495
79.070
89.034
90.485
81.585
85.734
89.892
79.506
84.839
90.495
79.070
89.034
90.485

30
101.894
105.995
103.202
101.894
105.995
103.202

10
0.32566
0.3194
0.31809
0.32566
0.3194
0.31809

10
90.649
88.339
87.856
90.649
88.339
87.856

15
0.33679
0.33413
0.34677
0.33679
0.33413
0.34677

45
0.41858
0.42384
0.422
0.41858
0.42384
0.422

45
124.937
126.878
126.199
124.937
126.878
126.199

45
113.010
114.779
114.153
113.010
114.779
114.153

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6

TABLET
Generik 1
Generik 2
Generik 3
Generik 4
Generik 5
Generik 6
RATA2

10
90.649
88.339
87.856
90.649
88.339
87.856

Konsentrasi Terkoreksi
Waktu ( Menit)
15
20
30
95.260
99.880
113.215
94.266
100.550
117.773
98.927
100.539
114.669
95.260
99.880
113.215
94.266
100.550
117.773
98.927
100.539
114.669

Persentase Terdisolusi (%)


Waktu ( Menit)
10
15
20
30
54.390
57.156
59.928
67.929
53.004
56.559
60.330
70.664
52.714
59.356
60.323
68.802
54.390
57.156
59.928
67.929
53.004
56.559
60.330
70.664
52.714
59.356
60.323
68.802
53.369
57.691
60.194
69.131

Waktu (menit)
R rata-rata
10
53.369
15
57.691
20
60.194
30
69.131

45

75.987

it)
45
125.566
127.533
126.836
125.566
127.533
126.836

it)
45
75.340
76.520
76.102
75.340
76.520
76.102
75.987

T rata-rata
58.847
60.777
63.931
66.343

R-T
-5.478
-3.086
-3.738
2.789

(R-T)^2
30.0100776228496
9.5254834875915
13.9691868634846
7.7760312351577

66.826

9.161
SUM
dibagi 6
1
SQRT
100/sqrt
50 log
F2

83.9234975563298
145.2042767654130
24.2007127942
25.2007127942
5.0200311547
19.920195098
64.964679379
64.964679379

Absorbansi Branded
Persamaan

Y= 0.0304x + 0.1019
0.0304

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

Tablet
Brand 1
Brand 2
Brand 3
Brand 4
Brand 5
Brand 6

10
3.36326667
2.9226
3.1554
3.0277
2.9291
3.10286667

0.1019

15
3.27473
3.1945
3.08157
3.1366
3.1011
3.1997

Waktu ( Menit)
20
3.27164
3.23624
3.43853
3.3176
3.3524
3.3274

30
3.43217
3.6945
3.247
3.4457
3.4882
3.3641

45
3.4407
3.25917
3.5641
3.5028
3.5329
3.5148

30

45

109.5484
118.1776
103.4572
109.9934
111.3914
107.3092

109.82895
103.85757
113.88816
111.87171
112.86184
112.26645

Konsentrasi Tiap Tablet (ppm)


Waktu ( Menit)
10
15
20
107.2818
92.786184
100.44408
96.243421
93
98.716009

104.3694
101.7303
98.01546
99.82566
98.65789
101.9013

104.2678
103.1033
109.7576
105.7796
106.9243
106.102

Massa terlarut dalam 900 mL (mg)


Waktu ( Menit)
10
15
20
96.554
94.469
94.366
83.508
92.021
93.304
90.400
88.716
99.275
86.619
90.324
95.703
83.700
89.257
96.728
88.844
92.205
96.004

30
99.118
106.878
93.663
99.526
100.790
97.112

45
99.397
94.066
103.020
101.237
102.136
101.579

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6

TABLET
Branded 1
Branded 2
Branded 3
Branded 4
Branded 5
Branded 6
RATA2

10
107.282
92.786
100.444
96.243
93.000
98.716

Konsentrasi Terkoreksi
Waktu ( Menit)
15
20
104.965
104.851
102.246
103.671
98.573
110.305
100.360
106.337
99.175
107.475
102.450
106.671

Persentase Terdisolusi (%)


Waktu ( Menit)
10
15
20
64.369
62.979
62.911
55.672
61.347
62.203
60.266
59.144
66.183
57.746
60.216
63.802
55.800
59.505
64.485
59.230
61.470
64.003
58.847
60.777
63.931

30
110.131
118.754
104.070
110.584
111.989
107.902

45
110.441
104.517
114.466
112.486
113.484
112.866

30
66.079
71.252
62.442
66.351
67.193
64.741
66.343

45
66.264
62.710
68.680
67.492
68.090
67.720
66.826