Authors
ABSTRACT
Mnica Tereza
Suldofski2
Paulino Yassuda Filho2
Ana Paula Kazue Beppu3
Everaldo Roberto de
Arajo Junior3
Gustavo Vicenzi3
Ricardo Yukiharu Tsuge
Yamamoto3
Nephrology Division,
School of Medicine
(UNIOESTE)
School of Pharmacy
(UNIOESTE)
3
School of Medicine
(UNIOESTE)
2
Correspondence to:
Luis Alberto Batista Peres
Rua So Paulo, 769/Ap. 901
Centro
Cascavel Paran Brazil
CEP: 85801-020
Fax: 55 (45) 3327-3413
E-mail: peres@certto.com.br
We declare no conflict of
interest.
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INTRODUCTION
Nephrolithiasis is a high prevalence disease
affecting mainly adults aged between 20 and
60 years.1,2 It is estimated that up to 12%
of the population will suffer an episode of
nephrolithiasis during lifetime and, depending on the type of stone, more than 50%
of them will have a recurrence within 10
years.2,3,4,5,6,7 Caucasians are more affected.2,8
Stone formation is related to hereditary fac-
RESULTS
One hundred and nine (109) patients underwent an
investigation of the chemical analysis of calculi, corresponding to 8.1% of the total cases considered for metabolic investigation of nephrolithiasis. The mean age of
these patients was 38.9+13.4 years (ranging from 5 to
77 years). In relation to the gender, 55 patients (50.5%)
were male. Regarding family history we obtained that
information from 100 patients, and it was positive in 65
(65%) of the cases.
Regarding the chemical analysis of the stone, 95 patients
(87.2%) had calcium oxalate, and this was the most frequent composition found. Table 1 shows the results of the
chemical analysis performed in these stones. In relation to
the results of metabolic investigation in patients who performed the chemical analysis, among those with calcium
oxalate calculi or uric acid calculi, hypercalciuria and hyperuricosuria were the most common metabolic disorders.
DISCUSSION
In this study, 1,342 patients with nephrolithiasis were assisted; of these 109 performed the chemical analysis of their
calculi. Calcium oxalate was the most prevalent chemical
component, which is consistent with findings from other
regions and corroborated by the literature.2,3
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Table 1
Chemical composition
Calcium oxalate
95
87%
Calcium carbonate
44
40%
Uric acid
23
21%
Ammonia
18
17%
Calcium phosphate
7%
Cystine
1%
Struvite
1%
96
190
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