Commentary
of Hematology-Oncology; Stanford University & Lucile Packard Childrens Hospital; Palo Alto, CA USA; 2Department of Pediatrics; The Childrens Hospital of
Montefiore; Bronx, NY USA
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Immunotherapy in osteosarcoma
Immunotherapy in osteosarcoma
12. Kushner BH, Kramer K, Cheung NK. Phase II trial of the anti-G(D2) monoclonal
antibody 3F8 and granulocyte-macrophage colony-stimulating factor for neuroblastoma.
J Clin Oncol 2001; 19:4189-94.
13. Gorlick R, Anderson P, Andrulis I, Arndt C, Beardsley GP, Bernstein M, et al. Biology
of childhood osteogenic sarcoma and potential targets for therapeutic development:
meeting summary. Clin Cancer Res 2003; 9:5442-53.
14. Olafsen T, Bruland OS, Zalutsky MR, Sandlie I. Cloning and sequencing of V genes
from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling. Nucl Med Biol 1995; 22:765-71.
15. Olafsen T, Bruland OS, Zalutsky MR, Sandlie I. Abundant tyrosine residues in the
antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3:
Application to radiolabeling. Acta Oncol 1996; 35:297-301.
16. Gorlick R, Huvos AG, Heller G, Aledo A, Beardsley GP, Healey JH, et al. Expression of
HER2/erbB-2 correlates with survival in osteosarcoma. J Clin Oncol 1999; 17:2781-8.
17. Chou AJ, Gorlick R. Chemotherapy resistance in osteosarcoma: current challenges and
future directions. Expert Rev Anticancer Ther 2006; 6:1075-85.
18. McArthur GA, Demetri GD, van Oosterom A, Heinrich MC, Debiec-Rychter M,
Corless CL, et al. Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: imatinib target exploration consortium study
B2225. J Clin Oncol 2005; 23:866-73.
19. Chou AJ, Geller DS, Gorlick R. Therapy for osteosarcoma: where do we go grom here?
Pediatric Drugs 2008; 10:315-27.
20. Marina N, Gebhardt M, Teot L, Gorlick R. Biology and therapeutic advances for pediatric osteosarcoma. Oncologist 2004; 9:422-41.
21. Kurzman ID, MacEwen EG, Rosenthal RC, Fox LE, Keller ET, Helfand SC, et al.
Adjuvant therapy for osteosarcoma in dogs: results of randomized clinical trials using
combined liposome-encapsulated muramyl tripeptide and cisplatin. Clin Cancer Res
1995; 1:1595-601.
22. Khanna C, Lindblad-Toh K, Vail D, London C, Bergman P, Barber L, et al. The dog as
a cancer model. Nat Biotechnol 2006; 24:1065-6.
23. Koshkina NV, Khanna C, Mendoza A, Guan H, DeLauter L, Kleinerman ES. Fasnegative osteosarcoma tumor cells are selected during metastasis to the lungs: the role
of the Fas pathway in the metastatic process of osteosarcoma. Mol Cancer Res 2007;
5:991-9.
24. Zhou Z, Lafleur EA, Koshkina NV, Worth LL, Lester MS, Kleinerman ES. Interleukin-12
upregulates Fas expression in human osteosarcoma and Ewings sarcoma cells by enhancing its promoter activity. Mol Cancer Res 2005; 3:685-91.
25. Bielack SS, Marina N, Ferrari S, Helman LJ, Smeland S, Whelan JS, et al. Osteosarcoma:
the same old drugs or more? J Clin Oncol 2008; 26:3102-3.
26. Hunsberger S, Freidlin B, Smith MA. Complexities in interpretation of osteosarcoma
clinical trial results. J Clin Oncol 2008; 26:3103-4.
27. Perales MA, Yuan J, Powel S, Gallardo HF, Rasalan TS, Gonzalez C, et al. Phase I/II
study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients
with advanced melanoma. Mol Ther 2008; 16:2022-9.
28. Yuan J, Gnjatic S, Li H, Powel S, Gallardo HF, Ritter E, et al. CTLA-4 blockade
enhances polyfunctional NY-ESO-1 specific T cell responses in metastatic melanoma
patients with clinical benefit. Proc Natl Acad Sci USA 2008; 105:20410-5.
29. Mackall CL, Rhee EH, Read EJ, Khuu HM, Leitman SF, Bernstein D, et al. A pilot
study of consolidative immunotherapy in patients with high-risk pediatric sarcomas.
Clin Cancer Res 2008; 14:4850-8.
30. Ullenhag GJ, Spendlove I, Watson NF, Kallmeyer C, Pritchard-Jones K, Durrant LG.
T-cell responses in osteosarcoma patients vaccinated with an anti-idiotypic antibody,
105AD7, mimicking CD55. Clin Immunol 2008; 128:148-54.
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