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Embryonic Development - Embryology

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Embryonic Development
From Embryology

Contents
1 Introduction
2 Carnegie Stages
3 Week 1
4 Week 2
5 Week 3
6 Week 4
7 Week 5
8 Week 6
9 Week 7
10 Week 8
11 Carnegie Stages
12 Carnegie Stage Table
13 Glossary Links

Introduction
[show] Author Comments
This page shows some
key events of human
development during the
embryonic period of the
first eight weeks (weeks
1 - 8) following
fertilization. This period
is also considered the
organogenic period,
when most organs
within the embryo have
begun to form.
There are links to more
detailed descriptions
which can be viewed in
a week by week format,
by the Carnegie stages

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or integrated into a
Timeline of human
development.
Online resources
available include:
individual images of all
Carnegie stages,
scanning electron
micrographs of the
earlier stages, crosssections showing
internal structures at
mid- and
late-embryonic, 3D
reconstructions of
internal structures,
animations of processes,
ultrasound scans and
information about
abnormalites of
development.
Note that there is
variability in the actual
timing of specific events
and at the end of this
period fetal development
begins.
Quicktime version
Bookmark with:

Carnegie Stages
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | About Stages | Timeline
Use the above stage number links to images and information about each
specific stage of human development over the first 8 weeks. The links below
give a broad overview of developmental events during each week.
Links: Carnegie stage 13 - serial sections | Carnegie stage 22 - serial
sections

Alternatively, look through development week by week.

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Week Links: Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | Week 6 | Week 7 | Week 8 | Week 9

Week 1
Week 1 Carnegie stage - 1 | 2 | 3 | 4
Oocyte | Spermatozoa | Fertilization
Zygote
Morula
Blastocyst
Carnegie stages

Week 1 - Early zygote

stage 1

stage 2

stage 3

stage 4

Week 2
Week 2 Carnegie stage - 5 | 6
Trophoblast - outer cell layer
Embryoblast - inner cell mass
Implantation
Bilaminar embryo
Carnegie stages
Week 2 Implantation

stage 5

stage 6

Week 3
Week 3 - Carnegie stage - 7 | 8 | 9
Gastrulation
Notochord
Trilaminar embryo
Mesoderm
Somitogenesis

Week 3 - Embryonic disc

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Embryonic Development - Embryology

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Neurogenesis
Carnegie stages

stage 7

stage 8

stage 9

Week 4
Week 4 - Carnegie stage - 10 | 11 | 12 | 13
Heart
Placodes
Pharyngeal arches
Carnegie stages

Week 4 - The heart


begins

stage 10

stage 11

stage 12

stage 13

Week 5
Week 5 - Carnegie stage - 14 to 15
Carnegie stages

stage 14

stage 15
Week 5 embryo

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Week 6
Week 6 - Carnegie stage - 16 to 17
Carnegie stages

Week 6 - Early face


deevelopment

stage 16

stage 17

Week 7
Week 7 - Carnegie stage - 18 to 19
Carnegie stages

stage 18

stage 19

Week 8
Week 8 - Carnegie stage - 20 | 21 | 22 | 23
Last week of embryonic development.

Week 7 - Head and limb


development

Carnegie stages

stage 20

stage 21

stage 22

stage 23

Carnegie Stages

Week 8 - Last embryonic stage


23

1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 |
22 | 23 | About Stages | Timeline

Carnegie Stage Table


Stage

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Days
(approx)

Size
(mm)

Images
(not to scale)

Events

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1
(week 1)

0.1 - 0.15

fertilized oocyte, zygote, pronuclei

2-3

0.1 - 0.2

morula cell division with reduction in cytoplasmic volume,


blastocyst formation of inner and outer cell mass

4-5

0.1 - 0.2

loss of zona pellucida, free blastocyst

5-6

0.1 - 0.2

attaching blastocyst

7 - 12
(week 2)

0.1 - 0.2

implantation

13 - 15

0.2

extraembryonic mesoderm, primitive streak, gastrulation

15 - 17
(week 3)

0.4

gastrulation, notochordal process

17 - 19

1.0 - 1.5

primitive pit, notochordal canal

19 - 21

1.5 - 2.5

Somitogenesis Somite Number 1 - 3 neural folds, cardiac


primordium, head fold

10

22 - 23
(week 4)

2 - 3.5

11

23 - 26

2.5 - 4.5

Somite Number 13 - 20 rostral neuropore closes

12

26 - 30

3-5

Somite Number 21 - 29 caudal neuropore closes

13

28 - 32
(week 5)

4-6

Somite Number 30 leg buds, lens placode, pharyngeal


arches

Somite Number 4 - 12 neural fold fuses

Stage 13/14 shown in serial embryo sections series of Embryology Program


14

31 - 35

5-7

lens pit, optic cup

15

35 - 38

7-9

lens vesicle, nasal pit, hand plate

16

37 - 42
(week 6)

8 - 11

nasal pits moved ventrally, auricular hillocks, foot plate

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17

42 - 44

11 - 14

finger rays

18

44 - 48
(week 7)

13 - 17

ossification commences

19

48 - 51

16 - 18

straightening of trunk

20

51 - 53
(week 8)

18 - 22

upper limbs longer and bent at elbow

21

53 - 54

22 - 24

hands and feet turned inward

Stage 22 shown in serial embryo sections series of Embryology Program


22

54 - 56

23 - 28

eyelids, external ears

23

56 - 60

27 - 31

rounded head, body and limbs

Following this stage Fetal Development occurs until birth (approx 40 weeks)
The embryos shown in the table are from the Kyoto collection and other sources, not from the Carnegie
collection.

Glossary Links
A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z | Numbers |
Symbols
Dr Mark Hill 2012, UNSW Embryology ISBN: 978 0 7334 2609 4 - UNSW CRICOS Provider Code No.
00098G

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Categories:
Human Embryo Carnegie Stage
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