PENGARUH DEKOKTA DAUN BENALU TEH (Scurrula Antopurpurea Bl.

Dans) DOSIS AKUT TERAPI,

MATC, DAN LC50 TERHADAP POLA SERTA KECEPATAN BERENANG IKAN ZEBRA DEWASA (Danio
Rerio)
Muchlissatus Sholichah, Nour Athiroh AS , Diah Andriana
Fakultas Kedokteran Universitas Islam Malang
E-mail: muchlissatussholichah@gmail.com
ABSTRAK
Pendahuluan : Penelitian ini bertujuan untuk mengetahui pengaruh benalu teh dosis akut terhadap perubahan pola
dan kecepatan berenang ikan zebra dewasa.
Introduction: This study aimed to determine the effects of S. Antopurpurea acute doses (menurutku mending nama
latinnya aja kalau tea parasite artinya bisa macam2) in changing patterns and swimming speed of adult zebra fish.
Metode : Penelitian dilaksanakan secara eksperimental laboratorium menggunakan desain penelitian control group
post test dengan menggunakan hewan coba ikan zebra jantan berumur tiga bulan yang telah diadaptasi selama satu
bulan sebanyak 64 ekor. Parameter pengamatan tersebut dengan dosis terapi 200 mg/L, MATC 3741 mg/L, dan LC 50
6282 mg/L meggunakan software tracker. Pola berenang ikan zebra dewasa yang telah dipapar dekokta daun benalu
teh selama 15 menit dengan pengamatan selama 30 menit pada menit ke 5, 10, 15, 20, 25. Kecepatan berenang ikan
zebra dewasa yang dipapar dekokta daun benalu teh selama 1 jam dan dilakukan pengamatan selama 1 menit.
Analisa data pola berenang dan kecepatan berenang menggunakan ANOVA (p<0.05).
Methods: This experimental research used control group post test design with three-month old zebra fish that has
been adapted for a month. The parameters are therapeutic dose of 200 mg / L, matc 3741 mg / L, and the LC50 6282
mg / L. The swim pattern of zebra fish that have been exposed to S. Antopurpurea leaves decocta for 15 minutes,
then observed for 30 minutes at 5, 10, 15, 20, 25 minute. The swimming speed of zebra fish that have been exposed
to S. Antopurpurea leaves decocta for 1 hour then observed in 1 minute. The data were analyzed by ANOVA (p
<0.05).
Hasil : Pengamatan pola berenang ikan zebra dewasa mengalami penurunan berenang tetapi P1 tidak berbeda nyata
dengan kontrol. Sedangkan kelompok kontrol dan P1 (dosis terapi) berbeda nyata dengan P2, P3. Namun P2 dan P3
tidak berbeda nyata. Pengamatan kecepatan berenang dewasa kontrol dan P1 tidak berbeda nyata. Tetapi jika di
bandingkan dengan P2 dan P3 berbeda nyata. Pada penelitian ini berhubungan dengan penyakit Parkinson yang
mengalami gangguan pada kerusakan degenerasi sel saraf secara bertahap pada otak bagian tengah yang berfungsi
mengatur pergerakan tubuh.
Results: Observation of adult zebra fish swimming patterns decreased swim but P1 is not significantly different from
controls. While the control group and P1 (therapeutic dose) significantly different from the P2, P3. However, P2 and
P3 were not significantly different. Observations adult swim speed control and P1 are not significantly different. But
if compared with P2 and P3 significantly different. In this study associated with Parkinson's disease who experience
a disruption in nerve cell degeneration gradually in the middle of the brain which controls the movement of the body.
Kesimpulan : Dekokta daun benalu teh dosis MATC dan LC 50 akut dapat mempengaruhi perubahan pola berenang
dan kecepatan berenang ikan zebra dewasa.
Conclusion: Dekokta leaf tea parasite MATCH dose and acute LC50 can influence changes in the pattern and speed
swim swimming adult zebrafish. (menyesuaikan yg diatas ya mbak)
Kata kunci : benalu teh, pola berenang , kecepatan berenang, ikan zebra
EFFECT DEKOKTA BENALU LEAF TEA (Scurrula Antopurpurea Bl. Dans) ACUTE DOSE THERAPY,
MATC , LC50 AND PATTERN OF SPEED AND ADULT SWIM ZEBRA FISH (Danio rerio)
Muchlissatus Sholichah, Nour Athiroh, Diah Andriana
Faculty of Medicine, Islamic University of Malang
E-mail: muchlissatussholichah@gmail.com
ABSTRACT

Introduction: This study aimed to determine the effects of acute doses tea parasite to changing patterns and adult
zebra fish swimming speed.
Methods: Research conducted in the laboratory of experimental research design posttest control group using
experimental animals zebrafish three-month old male who has been adapted for a month as many as 64 individuals.
Parameters such observations with a therapeutic dose of 200 mg / L, matc 3741 mg / L, and the LC50 6282 mg / L
receipts tracker software. The pattern of zebra fish swim adults who have been exposed dekokta parasite tea leaves
for 15 minutes with observation for 30 minutes at minute 5, 10, 15, 20, 25. Free swimming adult zebrafish exposed
dekokta parasite tea leaf for 1 hour and observation for 1 minute. Analysis of the data pattern of swimming and
swimming speed using ANOVA (p <0.05).
Results: Observation of adult zebra fish swimming patterns decreased swim but P1 is not significantly different from
controls. While the control group and P1 (therapeutic dose) significantly different from the P2, P3. However, P2 and
P3 were not significantly different. Observations adult swim speed control and P1 are not significantly different. But
if compared with P2 and P3 significantly different. In this study associated with Parkinson's disease who experience
a disruption in nerve cell degeneration gradually in the middle of the brain which controls the movement of the body.
Conclusion: Dekokta leaf tea parasite MATCH dose and acute LC50 can influence changes in the pattern and speed
swim swimming adult zebrafish.
Keywords: parasite tea, swimming patterns, speed swimming, zebrafish