All the events associated with the flow of blood through the heart during
a single complete heartbeat (approx 0.8sec if heart rate is 75bpm)
One heart beat may be divided into two sequential phases:
Diastole
Period of cardiac relaxation
Often an implied time of refilling, despite period of isovolumetric
relaxation
Systole
Period of cardiac contraction
Often an implied time of ejection, despite period of isovolumetric
contraction
Each phase may be applied to both atria and ventricles, therefore the
sequence of events (which may overlap) are:
atrial diastole ventricular diastole atrial systole ventricular
systole
Revise:
Cardiac anatomy
Action of valves
Valves open passively due to pressure gradients
AV valves open when P atria > P ventricles
Semilunar valves open when P ventricles > P arteries
Cardiac Cycle:
Mechanical Phases
1
START
Isovolumic ventricular
5 relaxation: as ventricles
relax, pressure in ventricles
falls, blood flows back into
cups of semilunar valves
and snaps them closed.
Ventricular ejection:
4 as ventricular pressure
rises and exceeds
pressure in the arteries,
the semilunar valves
open and blood is
ejected.
Isovolumic ventricular
contraction: first phase of
ventricular contraction pushes
AV valves closed but does not
create enough pressure to open
semilunar valves.
Silverthorn,
Silverthorn, fig 14-24, step 1-5
130 mL 70 mL = 60 mL
Cardiac Cycle:
Pressure-Volume curve/loop
KEY
EDV = End-diastolic volume
ESV = End-systolic volume
Stroke volume
120
D
ESV
80
C
One
cardiac
cycle
40
EDV
B
A
0
65
100
Left ventricular volume (mL)
135
Silverthorn,
Silverthorn, fig 14-25, (4 of 4)
Wiggers Diagram
0
Electrocardiogram
(ECG)
100
Time (msec)
200 300 400
QRS
complex
Atrial Ventricular
systole
systole
Atrial systole
Isovolumic
ventricular
contraction
Ventricular
systole
500
600
700
800
Cardiac cycle
T
P
Ventricular
diastole
Early
ventricular
diastole
QRS
complex
Atrial
systole
Late
ventricular
diastole
Atrial
systole
Silverthorn,
Silverthorn, fig 14-26, (1 of 13)
Wiggers Diagram
0
Electrocardiogram
(ECG)
Time (msec)
200 300 400
100
QRS
complex
500
600
700
800
QRS
complex
Cardiac cycle
T
120
Pressure
(mm Hg)
90
Aorta
Dicrotic
notch
Left
ventricular
pressure
60
Left atrial
30 pressure
Heart
sounds
Left
ventricular
volume
(mL)
Atrial systole
S1
S2
135
65
Isovolumic
ventricular
contraction
Atrial Ventricular
systole
systole
Ventricular
systole
Ventricular
diastole
Early
ventricular
diastole
Atrial
systole
Late
ventricular
diastole
Atrial
systole
Silverthorn,
Silverthorn, fig 14-26, (13 of 13)