Roopnarain
PRESIDENTS COLLEGE
CANDIDATE #:
DATE:
CAPE CHEMISTRY
Skill: P&D
UNIT 1
PRACTICAL # 7
Statement of problem: The Pharmacist at the local drugstore insists on the effectiveness of
Brand A antacid over Brand B antacid. Plan and design an experiment to determine the truth of
the pharmacists claim.
Hypothesis: Brand A antacid neutralises more stomach acid than Brand B antacid.
Aim: to plan and design an experiment to determine the effectiveness of Brand A antacid and
Brand B antacid
Variables
Dependent/ variables
1. Amount of HCl neutralized
2. The pink color change
3. The color change of pink to colorless
Independent variable
1. Brand B antacid
2. Brand A antacid
3. Standard NaOH
Controlled variable
1. Volume of HCl added
2. Mass of both antacid weighed
3. Volume of standard NaOH
Reagents
1. Brand A antacid
2. Brand B antacid
3. 200 cm3 HCl acid ( 0.1 mol/dm3)
4. Phenolphthalein indicator (1%)
5. Standard NaOH solution ( 0.1 mol/dm3)
Materials
9/12 B. Roopnarain
Formerly dissolve both samples of antacid in separate conical flask with 25 cm3 HCl
each and add one drop of Phenolphthalein indicator.
3.
Later fill the burette to the zero mark with NaOH, then used that burette to titrate over
the HCl until a pink coloration is seen (endpoint).
4.
Repeat the procedure with the other conical flask containing the other antacid and
precisely record the amounts of HCl added and then make necessary calculation.
5. Finally recap procedure 1, 2, 3 and 4 to gain maximum accuracy with the results, the
effectiveness of the antacid (that is the amount of HCl neutralised by antacid) can be
calculated by the amount of NaOH added into the HCl solution to neutralise it.
9/12 B. Roopnarain
Results:
The below table shows the amount of NaOH that was required to neutralise HCl (containing
antacid)
9/12 B. Roopnarain
Trial
Volume/cm3
Initial
Titration
Volume of
Volume of
NaOH
NaOH
A1
A2
Final
B1
B2
Titre
A1-B1= X1
A2-B2 = X2
The table below shows the break down calculations for the number of moles for the two
antacid used
9/12 B. Roopnarain
Antacid B
NO of Mole = M x volume
= Y mol/dm3 x 3X dm3
= 3XY moles HCl neutralised
Steps
1.
NO of Mole = M x volume
= Y mol/dm3 x 2X dm3
= 2XY moles HCl neutralised
Then this antacid is stronger since only 2XY
moles HCl was neutralised by NaOH to bring it
to endpoint. This showed that the antacid has
done some extra work in comparison to
Antacid B
Antacid A
2.
3.
4.
Assumptions:
The antacid A is more effective if less NaOH is needed to neutralize the HCl, that is, more HCl
was already neutralize by the antacid. Also if more moles of antacid is used up with the same
9/12 B. Roopnarain
amount of HCl then that HCl acid is more stronger/effective. This can be seen from the example
where Mg (OH)2 is used to demonstrate.
Conclusion
If the determining factor, that is, the number of moles of HCl neutralised by NaOH is less when
the Brand A antacid is used rather than when Brand B antacid is used then the hypothesis is
supported if not then the hypothesis is not supported.