Pharmacology exam first semester

Test 1
For questions 4-7 A. if a,b,c true, B. if a,c,d are true , C. if b,d are true, D. a, d are
true, E. if a, e are true
4. Antipsychotics:
a.
b.
c.
d.
e.

Decrease dopamine activity

Use In nausea and vomiting
Causing hallucination
Increase sympathetic activity
Lowers prolactin secretion

5. Cholinergic receptors
a.
b.
c.
d.
e.

Couple with G protein

Nuclear receptors
Ca channels
Na channels
Chloride channels

6. Atropine is useful for

a.
b.
c.
d.
e.

Diarrhea
Glaucoma
Neustigmine over
A-V block (atria ventricular block)
Lowers ilium intestinal paralysis

7. Which of the drugs are given iv (they need to be water soluble in order to pass in
the iv
a.
b.
c.
d.

Hydrocortisone
Hetiisuccinate
Dexamethasome
Sodium phosphate

8. For the following A- bind to dopamine receptors, B- produce extra pyramidal

effects, C- if both of them , D- if none of them
Carbidopa
Levodopa
Thrihexyphenide
Bromocreptine
Haloperidol

9. For the following A- causes respiratory depression, B- causes constipation, C- if both

of them , D- if none of them
Morphine
Codeine
Atropine
Heupstigmine
Paracetamol
10. Missing ! sorry

11. For the following A if both sentences are true and have a causal relation , B if
both sentences are true with no relation between them, C if just the first sentence is
true, D if just the second sentence is true, E if both sentences are false
11. cortical steroids are not used as treatment remathoid arthritis because they determine
osteoporosis
12.cardamazepin is useful in treating trigeminal neuralgia because it has enzymatic
inhibitors neuronal effects.
13. asprin has GI irritants effects because it is not absorbed through the stomach
14. Phenobarbital use of non conjugated hyperbilirubinemia because it produces anti
enzyme stimulation
15. isoprotenolol produce tachycardia because it has agonist action on beta receptors
16. morphine stimulate histamine release forbidden in treating acute cardio genetic
pulmonary edema.
17. soscumil choline tables by choline esterase because has esteric structure
18. non steroidal anti inflammatory may produce anaphylactic like effects because they
inhibit leukotramin
19. association of carvidopa and levodopa lowers systemic toxicity of levodopa
20. H1 blocking drugs use in treating bronchial asthma
21. hydrocortisone effects if given iv appears in few seconds
22. beta 2 androgenic receptors capsule with G proteins
Answers: 4-a, 5-d, 6-b, 7-c, 8- d,d,d,a,c , 9-c,b,b,d,d 10- missing, 11-d 12- c 13-c, 14-a, 15-b,
16-c, 17-a, 18-c, 19-T 20-F, 21-F, 22-T, 23-T

Test 2 :

For questions 4-7 A. if a,b,c true, B. if a,c,d are true , C. if b,d are true, D. a, d are
true, E. if a, e are true
4. The following drug are active on ion channel :
a.
b.
c.
d.
e.

Phenobarbital
Diazepam
Lidocaine
Epinephrine
Hydrocortisone

5. Morphine determines
a.
b.
c.
d.
e.

Miosis
Respiratory stimulation
Bronchospasm
Intracranial hypertension
A rise in blood pressure

6. The following drugs have anti muscarinic effects :

a.
b.
c.
d.
e.

Hyoscine
Amitriptilline
Pirenzepine
Pilocarpine
Suxamethonium

7. Haloperidol :
a.
b.
c.
d.
e.

Decreases dopamine activity

Increases sympathetic activity
May be used to treat nausea and vomiting
May be used against hallucinations
Lowers the prolactine secretion

8. For the following questions A if the drug has analgesic effects , B has antiinflammatory effects, C if both of them , D none of them
Acetaminophen
Naloxone
Ibuprofen
Prednisone
Morphine

9. For the follow question : A propranolol , B dobutamine , C both of them, D none

of them
Acts on beta receptors
Is contraindicated in bronchial asthma
Used as antiarrhytmic drugs
Used in the treatment of heart failure
Determines significant hepatic enzyme induction
10. For the following : A it bind to the dopaminergic receptors , B produces
extrapyramidal effects, C both of them, D none of them
Carbidopa
Levodopa
Trihexyphenidyl
Bromocriptine
Haloperidol
For the following A if both sentences are true and have a causal relation , B if both
sentences are true with no relation between them, C if just the first sentence is true,
D if just the second sentence is true, E if both sentences are false
11. Amitriptilline is contraindicated for the depressive patients who also prostate
adenoma because it has anticholinergic effects
12. Dexamethasone is contraindicated in hypertension because it has an important
mineralocorticoid effects.
13. missing sorry
14. Phenobarbital is useful in the treatment of non conjugated hyperbilirubinemia
because it enhances the GABA ergic transmission
15. The corticosteroids are not used as a treatment for rheumatoid arthritis because
they determine osteoporosis.
16. Local anesthetics determine neuronal membrane hyperpolarization because
they block potassium channels.
17. Acetylsalicylic acid has gastro irritant effect because it is well absorbed from the
stomach.

18. Adrenaline determines tachycardia because it has agonist action on beta 2

adrenergic receptors.
True or false
19. The beta 2 adrenergic receptors are coupled with G proteins.
20. The H1 histamine blocking drugs are largely used in the treatment of allergic
reactions.
21. Metamizol is useful as an antipyretic.
22. Carvedilol has agonist activity on beta adrenoceptors.
23. Prazosin is useful as anti hypertensive agent.

Answers: 4-a , 5-b, 6-a, 7-b, 8-a,d,c,a,a, 9-c,a,a,b,d 10 like question 8 first test. ,11a, 12-e, 14-b, 15-same as test 1 , 16-c 17-b, 18-b, 19 T, 20-T, 21-T, 22-F, 23-T.