BIOL 2104 (CRN 11096) Spr 2015

CELL & MOLECULAR BIOLOGY: Quiz No. 2, 24 February 2015

Name (print) _________________________ Student Number _____________________

I pledge that the answers on this quiz are the sole efforts of myself. Violations of
this pledge will be adjudicated by the Virginia Tech Honor System.


Form A Signature _______________________________

Please provide the most accurate answer for the following questions and
statements.

1. Below is an image of Los Angeles Union (Train) Station. To begin with a full
hall and maintain a full hall, which of the following needs to happen? Comment [jgt1]: Consider what happens over time.
A. arrival of a few people, departure of a few people.
B. arrival of a many people, departure of many people.
C. arrival of a few people, departure of many people.
D. arrival of many people,
departure of a few people.















Match the correct process with the listed components Comment [jgt2]: Associate terms with prokaryotic
2. Prokaryotic translation A. DNA, RNA, sigma factor versus eukaryotic processes.

E B. DNA, RNA, TATA binding protein

3. Prokaryotic transcription C. DNA, RNA, release factor
A D. RNA, protein, capping factor
4. Eukaryotic translation E. RNA, protein, ribosome binding
D site
5. Eukaryotic transcription F. RNA, protein, mediator
B

1
BIOL 2104 (CRN 11096) Spr 2015
CELL & MOLECULAR BIOLOGY: Quiz No. 2, 24 February 2015


6. If a tripeptide (a short 3-amino acid peptide) consisted of Met-Cys-Ile how
many different DNA sequences (9 nucleotides long) could encode this
peptide? Use the table below to help formulate your answer. Comment [jgt3]: This is an exercise in combinatorial
A. two math. Met-1 possibility times cys-two possibilities times
ile-three possibilities equals 6.
B. four
C. six
D. eight

7. The nucleus from the skin cell of an adult frog can be put into an egg where
the egg nucleus has been destroyed; an embryo will develop and a tadpole
emerge. Which of the following mechanisms was demonstrated? Comment [jgt4]: What is the consequence of each of
A. Cellular identity can be maintained by cytosine methylation of genomic DNA. the possibile answers?

B. Cell identity can be maintained by transcriptional regulator proteins in the

cytosol that move to the nucleus and cause positive feedback regulation of
gene expression.

8. miRNA are RNA structures that function at which of the following steps of
gene expression? Comment [jgt5]: Pure memorization.
A. DNA replication
B. RNA transcription
C. mRNA translation
D. protein degradation

9. If I wanted to alter when a gene was expressed, I would want which of the
following mutations? Comment [jgt6]: Location of mutations has a distinct
A. point mutation in coding region effect.

B. point mutation in the promoter

C. exon shuffling
D. horizontal gene transfer

10. What is the difference between a point mutation and a single nucleotide
polymorphism? Comment [jgt7]: Memorization and comparison.
A. there is no difference
B. the frequency in a population of the species
C. one is lethal and the other is beneficial
D. both are lethal

2
BIOL 2104 (CRN 11096) Spr 2015
CELL & MOLECULAR BIOLOGY: Quiz No. 2, 24 February 2015

Name (print) _________________________ Student Number _____________________

I pledge that the answers on this quiz are the sole efforts of myself. Violations of
this pledge will be adjudicated by the Virginia Tech Honor System.


Form B Signature _______________________________

Please provide the most accurate answer for the following questions and
statements.

1. Below is an image of Los Angeles Union (Train) Station. To begin with a full
hall and reduce to a half empty hall, which of the following needs to happen?
A. arrival of a few people, departure of a few people.
B. arrival of a many people, departure of many people.
C. arrival of a few people, departure of many people.
D. arrival of many people,
departure of a few people.















Match the correct process with the listed components
2. Prokaryotic translation A. DNA, RNA, release factor
E B. DNA, RNA, TATA binding protein
3. Prokaryotic transcription C. DNA, RNA, sigma factor
C D. RNA, protein, mediator
4. Eukaryotic translation E. RNA, protein, ribosome binding site
E F. RNA, protein, capping factor
5. Eukaryotic transcription
B

1
BIOL 2104 (CRN 11096) Spr 2015
CELL & MOLECULAR BIOLOGY: Quiz No. 2, 24 February 2015


6. If a tripeptide (a short 3-amino acid peptide) consisted of Met-Tyr-His how
many different DNA sequences (9 nucleotides long) could encode this
peptide? Use the table below to help formulate your answer.
A. two
B. four
C. six
D. eight

7. The nucleus from the skin cell of an adult frog can be put into an egg where
the egg nucleus has been destroyed; an embryo will develop and a tadpole
emerge. Which of the following mechanisms was demonstrated?
A. Cell identity can be maintained by transcriptional regulator proteins in
the cytosol that move to the nucleus and cause positive feedback
regulation of gene expression.
B. Cellular identity can be maintained by cytosine methylation of genomic
DNA.


8. siRNA are RNA structures that function at which of the following steps of
gene expression?
A. DNA replication
B. RNA transcription
C. mRNA translation
D. protein degradation

9. If I wanted to alter where a gene was expressed, I would want which of the
following mutations?
A. point mutation in coding region
B. point mutation in the promoter
C. exon shuffling
D. horizontal gene transfer

10. What is the difference between a point mutation and a single nucleotide
polymorphism?
A. there is no difference
B. the frequency in a population of the species
C. one is lethal and the other is beneficial

2
BIOL 2104 (CRN 11096) Spr 2015
CELL & MOLECULAR BIOLOGY: Quiz No. 2, 24 February 2015

D. both are lethal