PG/MICRO/I Email:sidharta123@yahoo.com
Time: 60 min Total Marks: 100 | Pass Mark: 60
Clinical Microbiology
MCQ Test Series based on Post Graduate Exam Preparation. Read the instructions
at the begining carefully. This is a Sample Practice Paper on Clinical Microbiology.
10. Which of the following is not a characteristic property of Polyomaviruses (BK virus)?
A belongs to Parvoviridae family C late region codes for SV40 large
tumor (T) antigen
B circular double-stranded DNA
D nonenveloped, icosahedral, 45 nm in
diameter
11. Precipitation reaction:
A precipitin band formed at the zone of C monoclonal antibodies are used in
equivalence precipitin reactions
B precipitin band formed at the zone of D zone of antibody excess exhibits
antigen excess optimal ratio for precipitation
12. A virus etiologically linked to Burkitts lymphoma:
A Rous sarcoma virus C Human herpesvirus 8
B Epstein-Barr (EB) virus D Cytomegalovirus
16. The test to determine Minimal inhibitory concentration (MIC) employs what method/technique?
A Dilution technique C Western blot technique
B Disk-agar diffusion method D Subculturing technique
21. Which of the following viruses has Single-stranded DNA in its genome?
A Reoviridae C Poxviridae
B Parvoviridae D Adenoviridae
28. All of the following agents are useful to treat the donor tissue before transplant in order to
reduce Graft-versus-host (GVH) reaction except:
A Monoclonal antibodies C Interleukin (IL)-2
B Antithymocyte globulin D Cyclosporine
40. A drug that causes radical cure by eliminating exoerythrocytic forms of malarial parasites in
the liver:
A Halofantrine C Chloroquine phosphate
B Quinine sulfate D Primaquine
43. Which of the following organ transplants have the highest rate of success?
A Bone marrow C Heart
B Cornea D Kidney
A B henselae C S moniliformis
B B pertussis D B bacilliformis
58. Anti-malarial drug(s) that does not prevent relapse and has no gametocidal activity:
A Artemisinin C Chloroquine
B Mefloquine D Primaquine
59. Type of glass container suitable for non-aqueous preparations for parental use:
A Type II glass containers C Type I glass containers
B Type IV glass containers D Type III glass containers
63. T-helper TH2 cells produces all of the following cytokines except:
A IL-2 C IL-4
B TNF- D IL-5
64. Which of the following obligate intracellular parasites are not cells and do not have a nucleus?
A Viruses C Bacteria
B Protozoa D Fungi
66. The virus that causes Korean hemorrhagic fever belongs to which genus?
A Alphavirus C Hantavirus
B Orbivirus D Flavivirus
71. Which of the following sterilization processes readily inactivates (kills) Spores?
A Autoclave C Boiling
B Ultraviolet light D Desiccation
74. In the USA, S aureus is resistant if the minimum inhibitory concentration (MIC) is:
A MIC is = 2 g/mL C MIC is =16 g/mL
B MIC is = 4 g/mL D MIC is =8 g/mL
75. Among the following agents responsible for congenital defects in fetus, which one is the lytic
virus that may cause fetal death?
A Cytomegalovirus C Varicella-zoster
B Herpes simplex D Rubella virus
77. Regarding Pulsed-field gel electrophoresis, which of the following statements is/are correct?
A uses a thermal cycler with an C uses a constant electrical field with an
illuminator to detect fluorescence uniform voltage gradient
B used for separation of large DNA D used for separation of small RNA
molecules molecules
82. Which of the following statements regarding Trivalent oral poliovaccine are correct?
A Trivalent oral poliovaccine is the Salk C Immune globulin is highly effective
vaccine following infection
B Should not be administered to an D Pregnancy is not a contraindication
immunosuppressed individual
83. What is the generality and common among interleukin (IL-1) and interleukin (IL-8)?
A Both IL-1 & IL-8 are derived from C Both IL-1 & IL-8 are chemoattractant
monocytes for eosinophils
B Both IL-1 & IL-8 are endogenous D Both IL-1 & IL-8 are derived from
pyrogens macrophages
84. Methyl-accepting chemotaxis proteins (MCPs) include all except:
A sucrose C serine
B galactose D maltose
86. Which of the following drugs inhibits the virus DNA polymerase?
A Zidovudine C Didanosine
B Saquinvir D Acyclovir
93. Rift Valley fever is due to the virus that belongs to genus
A Phlebovirus C Flavivirus
B Hantavirus D Orthobunyavirus
94. Which of the following is the most effective tool for conducting Genotyping assays?
A RT-qPCR C Multiple-locus VNTR analysis
B Nucleotide sequence analysis D Restriction fragment length
polymorphism
95. Linear, double-stranded DNA virus includes all of the following except:
A Herpesviruses C Adenoviruses
B Picornaviruses D Cytomegalovirus
99. Which of the following techniques was the first in nucleic acid isolation, amplification, and
sequencing?
A restriction endonuclease analysis C plasmid profile analysis
B ribotyping D nucleic acid sequence analysis
100. A form of cell wall growth characterized by cell wall synthesis at the septum and at the
equatorial rings is exhibited by:
A E coli C S pneumoniae
B B subtilis D S aureus
Disclaimer: Every attempt has been made to validate each and every question/answer. All remaining
errors are deeply regretted. Author will not be held responsible for any errors. Please consult the
standard textbooks given in the reference section for any discrepancy. Questions with wrong answers
may better be left unanswered. This is a practice series available free to download, and designed for
the benefit of prospective PG candidates and UG medical students alike.
Reference Textbooks:
1. Medical Microbiology: Jawetz, Melnick & Adelberg's, 24th Edition, Lange McGraw-Hill
publications
2. Microbiology: Prescott M. Lansing (Ed): Prescott- Harley- Klein, 5th Edition McGraw-Hill
publications