Figure 1 (left and center) An A-type and an E-type bisect are not engineered to perform the same way. Figure 2 (right) An example of a C-type
decreasing bisect on both the upper and lower faces of the tablet.
Tablet Specication Manual (The TSM), CHANGING BISECTS and disadvantages of this practice.
published by the American Association of Many existing tablets feature an E-Type
Pharmaceutical Scientists [1]. or standard bisect, but may not split References:
The seven types range from the most evenly when an individual attempts 1. Tableting Specications Manual, 7th edition,
functional bisect, called a G-type, which to diide them into equal doses [3]. In APhA Tableting Specication Steering Commit-
is very sensitive to pressure placed on such cases, the rm will need to explore tee, AphA Publishing, 2005.
it by humans, to the least functional or moving to either a C-, D- or G- type. 2. Pharmaceutical Dosage Forms, Vol. 2, 2nd Ed.
H-Type which is considered a cosmetic One needs to recognize that making this New York: Marcel Dekker, Inc. 1989.
bisect. Figures 1 and 2 illustrate the change may result in the need to change 3. Wiggins, L: Cutting Pills in Half Saves Money,
apparent differences between an A-type the size of the letters or numbers. but is it Always Safe?, Gwinnett County Ga-
and a E-Type bisect. Under existing guidelines, the FDA zette, Feb. 8, 2006, gwinnettdailypost.com