DOI 10.1007/s00586-015-4369-0
ORIGINAL ARTICLE
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Outcomes in clinical studies are highly reliant on only patients who had at least one positive result (signifi-
patient-reported outcome measures. Therefore the use of cant decrease in pain levels even if temporary) from a CT-
instruments whose psychometric properties have been guided sacroiliac joint injection were included. A subset of
rigorously established for the condition it is meant to this cohort (28 patients) underwent percutaneous sacroiliac
measure is essential; without these clinical studies may joint fusion utilising SI-LOK (Globus Medical, Alton,
come under question [9]. Important and accepted psycho- UK) hydroxyapatite coated screws in a technique similar to
metric properties include reliability, validity and respon- previously described [4]. As part of the rehabilitation
siveness. Reliability defines whether the measure is protocol, these patients prospectively completed post-op-
dependable and reproducibility. Validity refers to an erative scores including SF-36, ODI, Majeed and EQ-5D-
instrument ability to measure what it is supposed to mea- 5L at a mean of 14 months. Post-operative review
sure. Validity consists of several types including content including routine radiographs rather than CT scans there-
validity (floor and ceiling effects), criterion validity (how fore fusion was not assessed in this study. The data were
an instrument compares to an accepted gold-standard collected and maintained prospectively in a computerized
instrument), and construct validity (if the instrument fol- database by an independent researcher.
lows expected non-controversial hypotheses). Responsive-
ness to change is the ability of the instrument to detect Internal consistency
clinically important changes following intervention [10].
To our knowledge there are no outcome instruments Pre-operative Majeed scores were used to establish overall
specifically designed or psychometrically assessed for internal consistency for the main domains and subcate-
sacroiliac joint pain due to dysfunction or degeneration. gories. A Cronbach alpha of [0.60 was considered
Thus, the aim of this study is to establish the psychometric acceptable [10].
properties of the Majeed scoring system specifically for
this condition. Content validity
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The Minitab software package (version 17.0) was used for Table 1 Floor and ceiling effects for the overall and separate
domains
all statistical analyses. Factor analysis utilising Cronbach
alpha was used as a measure of internal consistency. Domain (points) Floor effect Ceiling effect
Continuous data were tested for normality using the Overall Majeed Score (0100) 0 (0 %) 0 (0 %)
AndersonDarling test. For normally distributed data, sta- Pain (030) 28 (46.6 %) 1 (1.7 %)
tistical differences and relationships between groups were Work (020) 26 (43.3 %) 5 (8.3 %)
examined using the unpaired Students t test. Correlation Sitting (010) 32 (53.3 %) 0 (0 %)
between different outcome measures and health-related
Sexual intercourse (4) 25 (41.6 %) 9 (15 %)
VAS was tested using Pearson coefficient, r. Correlation
Standing (036) 0 (0 %) 2 (3.3 %)
between ordinal scales for pain or activity and the Majeed
A Walking aids (012) 1 (1.6 %) 22 (36.6 %)
score was tested using Spearmans rho, rs. For all statistical
B Gait unaided (012) 2 (3.3 %) 9 (15 %)
analyses, p values of \0.05 were considered significant.
C Walking distance (012) 1 (1.6 %) 2 (3.3 %)
Values have been expressed as mean standard deviation
of the mean (SD). Domains with high effects ([30 %) shown in bold
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systems with adequate good patient acceptance [7]. Even average follow-up of 36 months in 55 patients. These
though these multiple scoring systems are utilised in pelvic encouraging early and mid-term results have been repro-
ring injuries their psychometric assessment is fairly limited duced in other studies [3, 5]. However, questions still
in the literature. The Majeed score is one of the few tested remain if these early results on clinical outcome measures
and same as our study it showed construct validity; with would be sustained in the long term. In this respect Kibs-
good correlation with physical function domain of the SF- gard et al. [18] reported on a 23-year follow-up for open
36 [13, 14]. However, to our knowledge reliability and sacro-iliac fusion. The patients with successful 1-year
responsiveness to change had not been previously reported outcomes retained significantly improved function and
even for traumatic pelvic conditions. It could be argued reduced pain levels compared with the subgroup of patients
that since the sacroiliac joint is a constitution of both the with unsuccessful 1-year outcomes. Non-union rate was
pelvis and spine a back pain-specific rather than a pelvis- 10 % with worse long term results. However, even though
specific scoring system should be utilised in these patients. patients reported satisfaction with the procedure they still
In fact both the Majeed score and ODI; the most commonly had moderate disability and moderate to severe pain
used back pain score have fairly similar domains and 23 years after surgery. This dichotomy between patient
crossover questions. This is evidenced by the high corre- satisfaction and clinical outcome is known in surgical
lation (r = -0.712) we found between the two scores. management. This might be due to design of the patient-
Thus, we feel that with the Majeed score the ODI would be reported outcome measures utilised. Thus, possibly indi-
an adequate score to include in studies pertaining to this cating that disease-specific and in this case pelvic-specific
condition. However, to our knowledge the ODI has not measures might be required.
been validated for sacroiliac joint conditions. The inclusion In summary, the Majeed scoring system demonstrated
of only patients who had at least one positive result from a acceptable psychometric properties for outcome assess-
CT-guided intraarticular sacroiliac joint anaesthetic block ment in non-traumatic sacroiliac joint pain. Thus, its use in
constitutes a strength in this study. Also, most of our this condition is suitable. This would allow adequate
patients had positive response to fluroscopic-guided injec- assessment in the evolving treatment for this condition
tions before referral to our unit. This specifically allows for utilising a pelvic-specific patient reported outcome mea-
a potential homogenous patient cohort suffering from sure. However, some domains demonstrated suboptimal
sacroiliac joint pain with other sources of pain either performance indicating that improvement might be
excluded or confirmed as minor contributing sources. achieved with the development of an outcome measure
However, the diagnostic accuracy in this study could be specific for chronic sacroiliac joint pain.
improved on if a double-diagnostic CT block selection
criteria was utilised as established in facet joint therapies Acknowledgments We would like to thank Mark Goodson at the
University Hospital Llandough for data collection. As well as, Dr. Jan
[15]. In fact, a false-positive rate at around 20 % was Hermann Kuiper at Keele University for advice on study design.
reported for single sacroiliac joint injections [16]. Thus,
double comparative blocks with different agents would Compliance with ethical standards
eliminate false-positive responders or placebo responses.
Conflict of interest No benefits in any form have been received or
Albeit an unintended consequence of employing stricter
will be received from a commercial party related directly or indirectly
diagnostic criteria may result in more false-negatives, and to the subject of this article.
thus treatment from patients who might benefit [12]. The
fact that sacroiliac joint pain could be heterogeneous (intra-
or extraarticular sacroiliac joint pathology) with complex
and variable nerve supply, can make anaesthetic block References
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