NATIONAL

ESSENTIAL MEDICINES
LIST OF PAKISTAN

Ministry of Health
Government of Pakistan
Islamabad

2007

 CONTENTS

PREFACE. i

NATIONAL ESSENTIAL MEDICINES LIST

FOURTH REVISION

Explanatory Notes .......................................................... ii

1: ANAESTHETICS............................................................ 1
1.1 General Anaesthetics and Oxygen..................... 1
1.2 Local Anaesthetics..............................................1
1.3 Preoperative medication and sedation for short term procedure1
2: ANALGESICS, ANTIPYRETICS, NON-
STEROIDAL ANTI-INFLAMMATORY MEDICINES, MEDICINES USED TO TREAT GOUT
AND DISEASE MODIFYING AGENTS IN RHEMATOID DISORDERS..2
2.1 Non-Opioids and Non steroidal Anti inflammatory medicines..2
2.2 Opioid Analgesics ..............................................2
2.3 Medicines used to treat gout. 2
2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)2
3: ANTI-ALLERGICS AND MEDICINES USED IN
ANAPHYLAXIS..............................................................3
4: ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS.3
4.1 Non-specific..3
4.2 Specific.3
5: ANTICONVULSANTS/ANTIEPILEPTICS ...................4
6: ANTI-INFECTIVE MEDICINES ...................................5
6.1 Anthelmintics ............................................................5
6.1.1 Intestinal Anthelminthics5
6.2 Antibacterials......................................................5
6.2.1 Beta Lactam medicines......................................5
6.2.2 Other Antibacterials.6
6.2.3 Antileprosy medicines.7
6.2.4 Antituberculosis medicines7
6.3 Antifungal Medicines .........................................9
6.4 Antiviral Medicines ............................................9
6.4.1 Antiherpes Medicines..9
6.4.2 Antiretovirals..9
6.4.2.1 Nucleoside/Nucleotide reverse transcriptase inhibitors..9
6.4.2.2 Non-nucleoside reverse transcriptase inhibitors..10
6.4.2.3 Protease Inhibitors.10
6.4.3 Other Antivirals11
6.5 Antiprotozoal Medicines..11
6.5.1 Antiamoebic and Antigiardiasis Medicines11
6.5.2 Antileishmaniasis Medicines12
6.5.3 Antimalarial Medicines12
6.5.3.1 For Curative Treatment12
6.5.3.2 For Prophylaxis.. 13
6.5.4 Antipneumocystosis and Antitoxoplasmosis Medicines..13
7. ANTIMIGRAINE MEDICINES.13
7.1 For Treatment of Acute Attack.13
7.2 For Prophylaxis.14
8. ANTINEOPLASTIC, IMMUNOSUPRESSIVES..14
8.1 Immunosuppressive Medicines..14
8.2 Cytotoxic Medicines.14
8.3 Hormones and Antihormones.15
9. ANTIPARKINSONISM MEDICINES..15
10. MEDICINES AFFECTING THE BLOOD.15
10.1 Antianaemia Medicines ....................................15
10.2 Medicines Affecting Coagulation15
11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES.16
11.1 Plasma Substitutes16
11.2 Plasma Fractions for Specific Use16
12. CARDIOVASCULAR MEDICINES16
12.1 Antianginal Medicines..16
12.2 Antiarrhythmic Medicines.16
12.3 Antihypertensive Medicines.17
12.4 Medicines Used in Heart Failure18
12.5 Antithrombotic Medicines.18
12.6 Lipid-Lowering Agents18
13. DERMATOLOGICAL MEDICINES (TOPICAL)..18
13.1 Antifungal medicines.18
13.2 Anti-Infective Medicines19
13.3 Anti-Inflammatory and Antipruritic Medicines..19
13.4 Astringent Medicines19
13.5 Medicines Affecting Skin Differentiation and Proliferation19
13.6 Scabicides and Pediculicides.19
14. DIAGNOSTIC AGENTS.20
14.1 Ophthalmic Medicines20
14.2 Radiocontrast Media20
15. DISINFECTANTS AND ANTISEPTICS.20
15.1 Antiseptics.20
15.2 Disinfectants20
16. DIURETICS .....................................................20
17. GASTROINTESTINAL MEDICINES..21
17.1 Antacids and other Antiulcer Medicines21
17.2 Antiemetic Medicines21
17.3 Anti-Inflammatory medicines..21
17.4 Laxatives21
17.5 Medicines used in Diarrhoea..21
17.5.1 Oral Rehydration21
17.5.2 Medicines for Diarrhoea in Children22
17.5.3 Antidiarrhoeal (symptomatic) Medicines in Adults..22
18. HORMONES, OTHER ENDOCRINE MEDICINES AND CONTRACEPTIVES22
18.1 Androgens22
18.2 Contraceptives..22
18.2.1 Oral Hormonal Contraceptives..22
18.2.2 Injectable Hormonal Contraceptives.23
18.2.3 Intrauterine Devices..23
18.2.4 Barrier Methods................................................23
18.2.5 Implantable Contraceptives..23
18.3 Estrogens23
18.4 Insulins and other Antidiabetic Agents23
18.5 Ovulation Inducers.23
18.6 Progestogens.24
18.7 Thyroid Hormones and Antithyroid Medicines.24
19. IMMUNOLOGICALS..24
19.1 Diagnostic Agents24
19.2 Sera and Immunoglobulins24
 19.3 Vaccines25
20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND CHOLINESTERASE
INHIBITORS ...................................................26
21. OPHTHALMOLOGICAL PREPARATIONS26
21.1 Anti-Infective Agents26
21.2 Anti-Inflammatory Agents..26
21.3 Local Anaesthetics..26
21.4 Miotics and Antiglaucoma Medicines..26
21.5 Mydriatics.26
22. OXYTOCICS AND ANTIOXYTOCICS..27
22.1 Oxytocics27
22.2 Antioxytocics (Tocolytics)..27
23. PERITONEAL DIALYSIS SOLUTION.27
24. PSYCHOTHERAPEUTIC MEDICINES..27
24.1 Medicines used in Psychotic Disorders..27
24.2 Medicines used in Mood Disorders.27
24.2.1 Medicines used in Depressive Disorders.27
24.2.2 Medicines used in Bipolar Disorders.27
24.3 Medicines used in Generalized Anxiety and Sleep Disorders28
24.4 Medicines used for Obsessive Compulsive Disorders and Panic Attacks28
24.5 Medicines used in Substance Dependence Programmes28
25. MEDICINES ACTING ON THE RESPIRATORY TRACT..28
25.1 Antiasthmatic and Medicines for Chronic Obstructive Pulmonary Disease..28
25.2 Other Medicines Acting on the Respiratory Tract..28
26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-BASE
DISTURBANCES.29
26.1 Oral.29
26.2 Parenteral29
26.3 Miscellaneous..29
27. VITAMINS AND MINERALS..29
INDEX ....................................................................... ..31

 PREFACE

After the second World War the development and emergence of miracle
medicines like antibiotics brought a revolution in the medical care. The obvious
effectiveness of these new pharmaceuticals and intensive marketing efforts
combined to catalyze wide spread use of modern medicine. A rapidly growing
and profitable industry, together with an enthusiastic but largely uninformed
audience and an unregulated market, resulted in excess of promotion and
consumption alowgwith inflated level of expenditure. However, by 1970s it had
become clear that least advantageous nations were not even meeting the basic
needs of their people for essential life saving and health promoting medicines. As
a result gradually a number of countries started concentrating on the
development of a basic list of reliable medicines to meet the most vital basic
needs of their people.

A World Health Organization (WHO) Committee of Experts met in 1977 to

determine the number of medicines, which were actually needed to ensure a
reasonable level of health care for as many people as possible. Consequently,
the first Model List of Essential medicines was finalized in the same year. This list
is being updated regularly by the WHO and is intended to be used as a guideline
and provide basis for member countries to identify their own priorities and make
their own selection. Through 1970s and 1980s the WHO started promotion of the
concept of Essential medicines Program in order to redress this imbalance. The
program aimed at reduction in the number of medicines purchased/used by the
hospitals/institutions to a minimum possible level in order to make best use of
limited public funds.

Essential medicines as defined by WHO are those that satisfy the health care
needs of majority of the population. They should therefore be available at all
times in adequate amounts and in the appropriate dosage forms.

The National Essential medicines List (NEML) of Pakistan was first prepared in
1994 in consultation with relevant experts. The list was previously reviewed in
1995, 2000 and 2003. The present list is the fourth revision containing 335
medicines of different pharmacological classes.

The health sector in general and public health sector in particular is expected to
seriously consider adopting this list. The provincial health departments can play a
pivotal role to encourage the hospitals/institutions for making bulk purchases
from within this list. We hope that this list will find more acceptance among health
care professionals.

Maj. Gen. Shahida Malik HI (M)

Director General Health

ExplanatoryNotes
Thecorelistpresentsalistofminimummedicineneedsforabasichealthcare
system,listingthemostefficacious,safeandcosteffectivemedicinesforpriority
conditions.Priorityconditionsareselectedonthebasisofcurrentandestimated
futurepublichealthrelevance,andpotentialforsafeandcosteffectivetreatment.

Thecomplementarylistpresentsessentialmedicinesforprioritydiseases,for
whichspecializeddiagnosticormonitoringfacilities,and/orspecialistmedical
care,and/orspecialisttrainingareneeded.
Thesquareboxsymbol()isprimarilyintendedtoindicatesimilarclinical
performancewithinapharmacologicalclass.

Dosageformsofmedicinesarelistedinalphabeticalorderandthereisno
implicationofpreferenceforoneformoveranother.Standardtreatment
guidelinesshouldbeconsultedforinformationonappropriatedosageforms.
Entriesofthetypeoralliquidareintendedtopermitanysolution,suspensionor
otherformofliquid.Granulesforreconstitutionasanoralliquidmaysubstitute
fororalliquids,andtypicallycarrybenefitsintheformofbetterstabilityand
lowertransportcosts.Ifmorethanonetypeoforalliquidisavailableonthe
samemarket(e.g.solution,suspension,granulesforreconstitution),theymaybe
interchangedandinsuchcasesshouldbebioequivalent.Itispreferablethatoral
liquidsdonotcontainsugarandthatsolutionsforchildrendonotcontain
alcohol.
Entriesofthetypetabletareintendedtoallowvariousformsofimmediaterelease
tabletsuchasuncoated,filmcoated,crushable,chewable,dispersibleetc.Enteric
coating,ontheotherhand,modifiesdrugrelease,andentericcoatedproductsare
amodifiedreleasedosageform.Crushable,chewableanddispersibletabletsmay
beeasiertoadministertopaediatricpopulationsandtotheelderly.
1. ANAESTHETICS
1.1 General anaesthetics and oxygen

halothane Inhalation.

ketamine Injection:50mg(ashydrochloride)/mlin10mlvial.

nitrousoxide Inhalation.

oxygen Inhalation(medicinalgas).

Powderforinjection:0.5g;1.0g(sodiumsalt)inampoule.
thiopental

1.2 Local anaesthetics

Injection:0.25%;0.5%(hydrochloride)invial.
bupivacaine Injectionforspinalanaesthesia:0.5%(hydrochloride)in
4mlampouletobemixedwith7.5%glucosesolution.

Injection:1%;2%(hydrochloride)invial.

Injectionforspinalanaesthesia:5%(hydrochloride)in2ml
lidocaine
ampouletobemixedwith7.5%glucosesolution.

Topicalforms:24%(hydrochloride).

Dentalcartridge:2%(hydrochloride)+epinephrine1:80000.
lidocaine+epinephrine
(adrenaline) Injection:1%;2%(hydrochloride)+epinephrine1:200000in
vial.

ComplementaryList

Injection:30mg(hydrochloride)/mlin1mlampoule.
ephedrine (Foruseinspinalanaesthesiaduringdelivery,toprevent
hypotension).

1.3 Preoperative medication and sedation for short-term procedures

atropine Injection:1mg(sulfate)in1mlampoule.

Injection:5mg/mlin2mlampoule.
diazepam
Tablet:5mg.

Injection:10mg(sulfateorhydrochloride)in1mlampoule.
morphine

promethazine Oralliquid:5mg(hydrochloride)/5ml.
2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-
INFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT
GOUT AND DISEASE MODIFYING AGENTS IN RHEUMATOID
DISORDERS (DMARDs)
2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs)

Suppository:50150mg.
acetylsalicylicacid
Tablet:100500mg.

ibuprofen Tablet:200mg;400mg.

Oralliquid:125mg/5ml.

Suppository:100mg.
paracetamol* Tablet:100500mg.

*Notrecommendedforantiinflammatoryuseduetolack
ofprovenbenefittothateffect.

diclofenac(asSodium) 75mg/3mlinj.(assodium)

2.2 Opioid analgesics

codeine Tablet:30mg(phosphate).

Injection:10mg(morphinehydrochlorideormorphine
sulfate)in1mlampoule.

Oralliquid:10mg(morphinehydrochlorideormorphine
morphine sulfate)/5ml.

Tablet:10mg(morphinesulfate).

Tablet(prolongedrelease):10mg;30mg;60mg(morphine
sulfate).

Pethidine 50 mg/ml inj. (as hydrochloride)

2.3 Medicines used to treat gout

allopurinol Tablet:100mg.

2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

chloroquine Tablet:100mg;150mg(asphosphateorsulfate).

ComplementaryList

azathioprine Tablet:50mg.

methotrexate Tablet:2.5mg(assodiumsalt).

penicillamine Capsuleortablet:250mg.

sulfasalazine Tablet:500mg.
1. ANAESTHETICS
1.1 General anaesthetics and oxygen

halothane Inhalation.

ketamine Injection:50mg(ashydrochloride)/mlin10mlvial.

nitrousoxide Inhalation.

oxygen Inhalation(medicinalgas).

Powderforinjection:0.5g;1.0g(sodiumsalt)inampoule.
thiopental

1.2 Local anaesthetics

Injection:0.25%;0.5%(hydrochloride)invial.
bupivacaine Injectionforspinalanaesthesia:0.5%(hydrochloride)in
4mlampouletobemixedwith7.5%glucosesolution.

Injection:1%;2%(hydrochloride)invial.

Injectionforspinalanaesthesia:5%(hydrochloride)in2ml
lidocaine
ampouletobemixedwith7.5%glucosesolution.

Topicalforms:24%(hydrochloride).

Dentalcartridge:2%(hydrochloride)+epinephrine1:80000.
lidocaine+epinephrine
(adrenaline) Injection:1%;2%(hydrochloride)+epinephrine1:200000in
vial.

ComplementaryList

Injection:30mg(hydrochloride)/mlin1mlampoule.
ephedrine (Foruseinspinalanaesthesiaduringdelivery,toprevent
hypotension).

1.3 Preoperative medication and sedation for short-term procedures

atropine Injection:1mg(sulfate)in1mlampoule.

Injection:5mg/mlin2mlampoule.
diazepam
Tablet:5mg.

Injection:10mg(sulfateorhydrochloride)in1mlampoule.
morphine

promethazine Oralliquid:5mg(hydrochloride)/5ml.
2. ANALGESICS, ANTIPYRETICS, NON-STEROIDAL ANTI-
INFLAMMATORY MEDICINES (NSAIMs), MEDICINES USED TO TREAT
GOUT AND DISEASE MODIFYING AGENTS IN RHEUMATOID
DISORDERS (DMARDs)
2.1 Non-opioids and non-steroidal anti-inflammatory medicines (NSAIMs)

Suppository:50150mg.
acetylsalicylicacid
Tablet:100500mg.

ibuprofen Tablet:200mg;400mg.

Oralliquid:125mg/5ml.

Suppository:100mg.
paracetamol* Tablet:100500mg.

*Notrecommendedforantiinflammatoryuseduetolack
ofprovenbenefittothateffect.

diclofenac(asSodium) 75mg/3mlinj.(assodium)

2.2 Opioid analgesics

codeine Tablet:30mg(phosphate).

Injection:10mg(morphinehydrochlorideormorphine
sulfate)in1mlampoule.

Oralliquid:10mg(morphinehydrochlorideormorphine
morphine sulfate)/5ml.

Tablet:10mg(morphinesulfate).

Tablet(prolongedrelease):10mg;30mg;60mg(morphine
sulfate).

Pethidine 50 mg/ml inj. (as hydrochloride)

2.3 Medicines used to treat gout

allopurinol Tablet:100mg.

2.4 Disease modifying agents used in rheumatoid disorders (DMARDs)

chloroquine Tablet:100mg;150mg(asphosphateorsulfate).

ComplementaryList

azathioprine Tablet:50mg.

methotrexate Tablet:2.5mg(assodiumsalt).

penicillamine Capsuleortablet:250mg.

sulfasalazine Tablet:500mg.
 3. ANTIALLERGICS AND MEDICINES USED IN ANAPHYLAXIS
Injection:10mg(hydrogenmaleate)in1mlampoule.
chlorphenamine
Tablet:4mg(hydrogenmaleate).

Injection:4mgdexamethasonephosphate(asdisodiumsalt)
dexamethasone
in1mlampoule.

Injection:1mg(ashydrochlorideorhydrogentartrate)in
epinephrine(adrenaline)
1mlampoule.

hydrocortisone Powderforinjection:100mg(assodiumsuccinate)invial.

Tablet:5mg;25mg
prednisolone* *Thereisnoevidenceforcompleteclinicalsimilarity
betweenprednisoloneanddexamethasoneathighdoses.

4. ANTIDOTES AND OTHER SUBSTANCES USED IN POISONINGS

4.1 Non-specific

charcoal,activated Powder.

4.2 Specific

acetylcysteine Injection:200mg/mlin10mlampoule.

atropine Injection:1mg(sulfate)in1mlampoule.

calciumgluconate Injection:100mg/mlin10mlampoule.

deferoxamine Powderforinjection:500mg(mesilate)invial.

dimercaprol Injectioninoil:50mg/mlin2mlampoule.

DLmethionine Tablet:250mg.

methylthioniniumchloride
Injection:10mg/mlin10mlampoule.
(methyleneblue)

Injection:400micrograms(hydrochloride)in1ml
naloxone
ampoule.

penicillamine Capsuleortablet:250mg.

potassiumferric
hexacyanoferrate(II)2H20 Powderfororaladministration.
(Prussianblue)

sodiumcalciumedetate Injection:200mg/mlin5mlampoule.
sodiumnitrite Injection:30mg/mlin10mlampoule.

sodiumthiosulfate Injection:250mg/mlin50mlampoule.

5. ANTICONVULSANTS/ANTIEPILEPTICS
Oralliquid:100mg/5ml.

carbamazepine Tablet(chewable):100mg;200mg.

Tablet(scored):100mg;200mg.

Injection:5mg/mlin2mlampoule(intravenousor
diazepam
rectal).

Injection:500mg/mlin2mlampoule;500mg/mlin
10mlampoule.
magnesiumsulfate*
*Foruseineclampsiaandseverepreeclampsiaand
notforotherconvulsantdisorders.

Injection:200mg/ml(phenobarbitalsodium).

Oralliquid:15mg/5ml(asphenobarbitalor
phenobarbital
phenobarbitalsodium).

Tablet:15100mg(phenobarbital).

Capsule:25mg;50mg;100mg(sodiumsalt).
Injection:50mg/mlin5mlvial(sodiumsalt).
Oralliquid:2530mg/5ml.*

phenytoin Tablet:25mg;50mg;100mg(sodiumsalt).
Tablet(chewable):50mg.
*Thepresenceofboth25mg/5mland30mg/5ml
strengthsonthesamemarketwouldcauseconfusionin
prescribinganddispensingandshouldbeavoided.
Oralliquid:200mg/5ml.

Tablet(crushable):100mg.
valproicacid
Tablet(entericcoated):200mg;500mg(sodium
valproate).

ComplementaryList

Capsule:250mg.
ethosuximide
Oralliquid:250mg/5ml.
6. ANTI-INFECTIVE MEDICINES
6.1 Anthelminthics
6.1.1 Intestinal anthelminthics

albendazole Tablet(chewable):400mg.

levamisole Tablet:50mg;150mg(ashydrochloride).

mebendazole Tablet(chewable):100mg;500mg.

niclosamide* Tablet(chewable):500mg.

Oralliquid:50mg(asembonate)/ml.
pyrantel
Tablet(chewable):250mg(asembonate).

ivermectin Tablet(scored):3mg;6mg.

6.2 Antibacterials
6.2.1 Beta Lactam medicines

Capsuleortablet:250mg;500mg(anhydrous).
amoxicillin
Powderfororalliquid:125mg(anhydrous)/5ml.

amoxicillin+clavulanic
Tablet:500mg+125mg.
acid

ampicillin Powderforinjection:500mg;1g(assodiumsalt)invial.

benzathine Powderforinjection:1.44gbenzylpenicillin(=2.4millionIU)
benzylpenicillin in5mlvial.

Powderforinjection:600mg(=1millionIU);3g(=5
benzylpenicillin
millionIU)(sodiumorpotassiumsalt)invial.

Powderforinjection:1g(assodiumsalt)invial.
cefazolin*
*Forsurgicalprophylaxis.

Capsule:400mg.
cefixime* *Onlylistedforsingledosetreatmentofuncomplicated
anogenitalgonorrhoea.

Capsule:500mg;1g(assodiumsalt).

cloxacillin Powderforinjection:500mg(assodiumsalt)invial.

Powderfororalliquid:125mg(assodiumsalt)/5ml.
 Powderfororalliquid:250mg(aspotassiumsalt)/5ml.
phenoxymethylpenicillin
Tablet:250mg(aspotassiumsalt).

Powderforinjection:1g(=1millionIU);3g(=3millionIU)
procainebenzylpenicillin
invial.

ComplementaryList

ceftazidime Powderforinjection:250mg(aspentahydrate)invial.

ceftriaxone Powderforinjection:250mg,1g(assodiumsalt)invial.

Powderforinjection:250mg(asmonohydrate)+250mg(assodium
imipenem*+ salt);500mg(asmonohydrate)+500mg(assodiumsalt)invial.
cilastatin* *Onlylistedforthetreatmentoflifethreateninghospitalbasedinfection
duetosuspectedorprovenmultidrugresistantinfection.

6.2.2 Other antibacterials

Capsule:250mgor500mg.

Oralliquid:200mg/5ml.
azithromycin*
*OnlylistedforsingledosetreatmentofgenitalChlamydia
trachomatisandoftrachoma.

Capsule:250mg.

Oilysuspensionforinjection:0.5g(assodium
chloramphenicol succinate)/mlin2mlampoule.

Oralliquid:150mg(aspalmitate)/5ml.

Powderforinjection:1g(sodiumsuccinate)invial.

Tablet:250mg(ashydrochloride).
ciprofloxacin*
*Finalselectiondependsonindicationforuse.

Capsuleortablet:100mg(hydrochloride).
doxycycline*
*Finalselectiondependsonindicationforuse.

Capsuleortablet:250mg(asstearateorethylsuccinate).

Powderforinjection:500mg(aslactobionate)invial.
erythromycin
Powderfororalliquid:125mg/5ml(asstearateorethyl
succinate).

Injection:10mg;40mg(assulfate)/mlin2mlvial.
gentamicin*
*Finalselectiondependsonindicationforuse.
 Injection:500mgin100mlvial.

Oralliquid:200mg(asbenzoate)/5ml.
metronidazole
Suppository:500mg;1g.

Tablet:200500mg.

nitrofurantoin Tablet:100mg.

spectinomycin Powderforinjection:2g(ashydrochloride)invial.

Injection:80mg+16mg/mlin5mland10mlampoules.
sulfamethoxazole+
Oralliquid:200mg+40mg/5ml.
trimethoprim
Tablet:100mg+20mg;400mg+80mg.

trimethoprim Tablet:100mg;200mg.

500mgtablet,300mg/5mlsyrup.
nalidixicacid
5000,000IUtab,100,000IU/mldrops,100,000IUpessaries

ComplementaryList

Capsule:150mg.
clindamycin
Injection:150mg(asphosphate)/ml.

Injection:250mg(sodiumsalt)in4mlampoule.Tablet:500
sulfadiazine
mg.

Powderforinjection:250mg(ashydrochloride)
vancomycin invial.

6.2.3 Antileprosy medicines

Medicinesusedinthetreatmentofleprosyshouldneverbeusedexceptincombination.
Combinationtherapyisessentialtopreventtheemergenceofdrugresistance.

clofazimine Capsule:50mg;100mg.

dapsone Tablet:25mg;50mg;100mg.

rifampicin Capsuleortablet:150mg;300mg.

6.2.4 Antituberculosis medicines

ethambutol Tablet:100400mg(hydrochloride).
 Tablet:100300mg.
isoniazid
Tablet(scored):50mg.

isoniazid+ethambutol Tablet:150mg+400mg.

Tablet:400mg.

pyrazinamide Tablet(dispersible):150mg.

Tablet(scored):150mg.

rifampicin Capsuleortablet:150mg;300mg.

Tablet:

60mg+30mg;150mg+75mg;300mg+
150mg.
rifampicin+isoniazid 60mg+60mg(Forintermittentusethree
timesweekly).

150mg+150mg(Forintermittentusethree
timesweekly).

rifampicin+isoniazid+ethambutol Tablet:150mg+75mg+275mg.

Tablet:

60mg+30mg+150mg;150mg+75mg+
rifampicin+isoniazid+pyrazinamide 400mg.

150mg+150mg+500mg(Forintermittent
usethreetimesweekly).

rifampicin+isoniazid+pyrazinamide
Tablet:150mg+75mg+400mg+275mg.
+ethambutol

streptomycin Powderforinjection:1g(assulfate)invial.

ComplementaryList

amikacin Powderforinjection:1000mginvial.

paminosalicylic Granules:4ginsachet.
acid Tablet:500mg.

capreomycin Powderforinjection:1000mginvial.

cycloserine Capsuleortablet:250mg.

ethionamide Tablet:125mg;250mg.
 kanamycin Powderforinjection:1000mginvial.

Tablet:200mg;400mg.
ofloxacin* *Levofloxacinmaybeanalternativebasedonavailabilityand
programmeconsiderations.

6.3 Antifungal medicines

Vaginalcream:1%;10%.
clotrimazole
Vaginaltablet:100mg;500mg.

Capsule:50mg.

fluconazole Injection:2mg/mlinvial.

Oralliquid:50mg/5ml.

griseofulvin Capsuleortablet:125mg;250mg.

Lozenge:100000IU.

nystatin Pessary:100000IU.

Tablet:100000IU;500000IU.

ComplementaryList

amphotericinB Powderforinjection:50mginvial.

Capsule:250mg.
flucytosine
Infusion:2.5gin250ml.

potassiumiodide Saturatedsolution.

6.4 Antiviral medicines

6.4.1 Antiherpes medicines

Powderforinjection:250mg(assodiumsalt)invial.
aciclovir
Tablet:200mg.

6.4.2 Antiretrovirals
6.4.2.1 Nucleoside/Nucleotide reverse transcriptase inhibitors

Oralliquid:100mg(assulfate)/5ml.
abacavir(ABC)
Tablet:300mg(assulfate).
 Bufferedpowderfororalliquid:100mg;167mg;250mg
packets.

Capsule(unbufferedentericcoated):125mg;200mg;250mg;
didanosine(ddI)
400mg.

Tablet(bufferedchewable,dispersible):25mg;50mg;100mg;
150mg;200mg.

Capsule:200mg.

Oralliquid:10mg/ml.
emtricitabine(FTC)*
*FTCisanacceptablealternativeto3TC,basedonknowledge
ofthepharmacology,theresistancepatternsandclinicaltrialsof
antiretrovirals.

Oralliquid:50mg/5ml.
lamivudine(3TC)
Tablet:150mg.

Capsule:15mg;20mg;30mg;40mg.*

*TheCommitteeexpectsthisdosageformtobereviewedfor
stavudine(d4T)
possibledeletionatthenextmeeting.

Powderfororalliquid:5mg/5ml.

tenofovirdisoproxil Tablet:300mg(tenofovirdisoproxilfumarateequivalentto245
fumarate(TDF) mgtenofovirdisoproxil).

Capsule:100mg;250mg.

zidovudine(ZDVor Oralliquid:50mg/5ml.
AZT) SolutionforIVinfusioninjection:10mg/mlin20mlvial.

Tablet:300mg.

6.4.2.2 Non-nucleoside reverse transcriptase inhibitors

Capsule:50mg;100mg;200mg.
efavirenz(EFVor
Oralliquid:150mg/5ml.
EFZ)
Tablet:600mg.

Oralliquid:50mg/5ml.
nevirapine(NVP)
Tablet:200mg.

6.4.2.3 Protease inhibitors

Ritonavirisrecommendedforuseincombinationasapharmacologicalbooster,andnot
asanantiretroviralinitsownright.
indinavir(IDV) Capsule:200mg;333mg;400mg(assulfate).

lopinavir+ritonavir Capsule:133.3mg+33.3mg.
(LPV/r) Oralliquid:400mg+100mg/5ml.

Oralpowder:50mg/g.
nelfinavir(NFV)
Tablet:250mg(asmesilate).

Oralliquid:400mg/5ml.
ritonavir
Oralsoliddosageform:100mg.

saquinavir(SQV) Capsule:200mg.

FIXED-DOSE COMBINATIONS

efavirenz+ Tablet:600mg+200mg+300mg.
emtricitabine*+
*FTCisanacceptablealternativeto3TC,basedonknowledge
tenofovir
ofthepharmacology,theresistancepatternsandclinicaltrials
ofantiretrovirals.

emtricitabine*+ Tablet:200mg+300mg.
tenofovir
*FTCisanacceptablealternativeto3TC,basedonknowledge
ofthepharmacology,theresistancepatternsandclinicaltrials
ofantiretrovirals.

stavudine+lamivudine Tablet:30mg+150mg+200mg.
+nevirapine

zidovudine+ Tablet:300mg+150mg.
lamivudine

zidovudine+ Tablet:300mg+150mg+200mg.
lamivudine+
nevirapine

6.4.3 Other antivirals

Injectionforintravenousadministration:1000mgand800mg
ribavirin in10mlphosphatebuffersolution.

Oralsoliddosageforms:200mg;400mg;600mg.

6.5 Antiprotozoal medicines

6.5.1 Antiamoebic and antigiardiasis medicines

diloxanide Tablet:500mg(furoate).
 Injection:500mgin100mlvial.

metronidazole Oralliquid:200mg(asbenzoate)/5ml.

Tablet:200500mg.

6.5.2 Antileishmaniasis medicines

sodiumstibogluconate
100mginj.
(S)

ComplementaryList

amphotericinB Powderforinjection:50mginvial.

6.5.3 Antimalarial medicines

6.5.3.1 For curative treatment

MedicinesforthetreatmentofP.falciparummalariacasesshouldbeusedincombination.

Tablet:153mgor200mg(ashydrochloride).

amodiaquine* *Tobeused(a)incombinationwithartesunate50mgOR(b)
maybeusedaloneforthetreatmentofP.vivax,P.ovaleand
P.malariaeinfections.

Oilyinjection:80mg/mlin1mlampoule.
artemether
Foruseinthemanagementofseveremalaria.

Tablet:20mg+120mg.
artemether+
lumefantrine* *Notrecommendedinthefirsttrimesterofpregnancyorin
childrenbelow5kg.

Injection:ampoules,containing60mganhydrousartesunicacid
withaseparateampouleof5%sodiumbicarbonatesolution.
Foruseinthemanagementofseveremalaria.
artesunate*
Tablet:50mg.

*Tobeusedincombinationwitheitheramodiaquine,
mefloquineorsulfadoxine+pyrimethamine.

Oralliquid:50mg(asphosphateorsulfate)/5ml.

chloroquine* Tablet:100mg;150mg(asphosphateorsulfate).

*ForuseonlyforthetreatmentofP.vivaxinfection.
 Capsule:100mg(ashydrochloride).

doxycycline* Tablet(dispersible):100mg(asmonohydrate).

*Foruseonlyincombinationwithquinine.

Tablet:250mg(ashydrochloride).
mefloquine*
*Tobeusedincombinationwithartesunate50mg.

Tablet:7.5mg;15mg(asdiphosphate)
primaquine* *OnlyforusetoachieveradicalcureofP.vivaxandP.ovale
infections,givenfor14days.

Injection:300mgquininehydrochloride/mlin2mlampoule.

Tablet:300mg(quininesulfate)or300mg(quininebisulfate).
quinine*
*Foruseonlyinthemanagementofseveremalaria,andshould
beusedincombinationwithdoxycycline.

sulfadoxine+ Tablet:500mg+25mg.
pyrimethamine* *Onlyincombinationwithartesunate50mg.

6.5.3.2 For prophylaxis

Oralliquid:50mg(asphosphateorsulfate)/5ml.

Tablet:150mg(asphosphateorsulfate).
chloroquine*
*ForuseonlyincentralAmericanregions,forusefor
P.vivax.

doxycycline Capsuleortablet:100mg(hydrochloride).

mefloquine Tablet:250mg(ashydrochloride).

Tablet:100mg(hydrochloride).
proguanil*
*Foruseonlyincombinationwithchloroquine.

6.5.4 Antipneumocystosis and antitoxoplasmosis medicines

pyrimethamine Tablet:25mg.

sulfamethoxazole+ Injection:80mg+16mg/mlin5mlampoule;80mg+
trimethoprim 16mg/mlin10mlampoule.

7. ANTIMIGRAINE MEDICINES
7.1 For treatment of acute attack

acetylsalicylicacid Tablet:300500mg.
paracetamol Tablet:300500mg.

7.2 For prophylaxis

propranolol Tablet:20mg;40mg(hydrochloride).

8. ANTINEOPLASTIC, IMMUNOSUPPRESSIVES

8.1 Immunosuppressive medicines

ComplementaryList

Powderforinjection:100mg(assodiumsalt)invial.
azathioprine
Tablet:50mg.

Capsule:25mg.
ciclosporin Concentrateforinjection:50mg/mlin1mlampoulefor
organtransplantation.

8.2 Cytotoxic medicines

ComplementaryList

asparaginase Powderforinjection:10000IUinvial.

bleomycin Powderforinjection:15mg(assulfate)invial.

Injection:3mg/mlin10mlampoule.
calciumfolinate
Tablet:15mg.

chlorambucil Tablet:2mg.

cisplatin Powderforinjection:10mg;50mginvial.

Powderforinjection:500mginvial.
cyclophosphamide
Tablet:25mg.

cytarabine Powderforinjection:100mginvial.

dacarbazine Powderforinjection:100mginvial.

dactinomycin Powderforinjection:500microgramsinvial.

daunorubicin Powderforinjection:50mg(ashydrochloride)invial.

doxorubicin Powderforinjection:10mg;50mg(hydrochloride)invial.

Capsule:100mg.
etoposide
Injection:20mg/mlin5mlampoule.

fluorouracil Injection:50mg/mlin5mlampoule.
 mercaptopurine Tablet:50mg.

Powderforinjection:50mg(assodiumsalt)invial.
methotrexate
Tablet:2.5mg(assodiumsalt).

procarbazine Capsule:50mg(ashydrochloride).

vinblastine Powderforinjection:10mg(sulfate)invial.

vincristine Powderforinjection:1mg;5mg(sulfate)invial.

8.3 Hormones and antihormones

ComplementaryList

Injection:4mgdexamethasonephosphate(asdisodiumsalt)in1ml
dexamethasone
ampoule.

hydrocortisone Powderforinjection:100mg(assodiumsuccinate)invial.

Tablet:5mg;25mg.
prednisolone* *Thereisnoevidenceforcompleteclinicalsimilaritybetween
prednisoloneanddexamethasoneathighdoses.

tamoxifen Tablet:10mg;20mg(ascitrate).

9. ANTIPARKINSONISM MEDICINES

procyclidine(S),(T) 5mg.tab.

levodopa+ Tablet:100mg+10mg;250mg+25mg.

10. MEDICINES AFFECTING THE BLOOD

10.1 Antianaemia medicines

Oralliquid:equivalentto25mgiron(assulfate)/ml.
ferroussalt
Tablet:equivalentto60mgiron.

ferroussalt+folic Tabletequivalentto60mgiron+400microgramsfolicacid
acid (Nutritionalsupplementforuseduringpregnancy).

folicacid Tablet:1mg;5mg.

hydroxocobalamin Injection:1mgin1mlampoule.

10.2 Medicines affecting coagulation

 Injection:1000IU/ml;5000IU/ml;20,000
heparinsodium
IU/mlin1mlampoule.

Injection:10mg/mlin5mlampoule.
phytomenadione
Tablet:10mg.

protaminesulfate Injection:10mg/mlin5mlampoule.

Tablet:1mg;2mg;5mg(sodiumsalt).

warfarin

11. BLOOD PRODUCTS AND PLASMA SUBSTITUTES

11.1 Plasma substitutes

Injectablesolution:6%.
dextran70* *Polygeline,injectablesolution,3.5%is
consideredasequivalent.

11.2 Plasma fractions for specific use

AllplasmafractionsshouldcomplywiththeWHORequirementsfortheCollection,
ProcessingandQualityControlofBlood,BloodComponentsandPlasmaDerivatives.

ComplementaryList

Intramuscularadministration:16%protein
humannormalimmunoglobulin solution.
Intravenousadministration:5%,10%protein
solution.
factorVIIIconcentrate Dried.

factorIXcomplex(coagulation
Dried.
factors,II,VII,IX,X)concentrate

12. CARDIOVASCULAR MEDICINES

12.1 Antianginal medicines

atenolol Tablet:50mg;100mg.

glyceryltrinitrate Tablet(sublingual):500micrograms.

isosorbidedinitrate Tablet(sublingual):5mg.

verapamil Tablet:40mg;80mg(hydrochloride).

12.2 Antiarrhythmic medicines

ThissubsectionwillbereviewedatthenextmeetingoftheExpertCommittee.

atenolol Tablet:50mg;100mg.

Injection:250micrograms/mlin2mlampoule.

digoxin
Oralliquid:50micrograms/ml.

Tablet:62.5micrograms;250micrograms.

Injection:100micrograms/ml(asacidtartrate
epinephrine(adrenaline)
orhydrochloride)in10mlampoule.

Injection:20mg(hydrochloride)/mlin5ml
lidocaine
ampoule.

Injection:2.5mg(hydrochloride)/mlin2mlampoule.
verapamil
Tablet:40mg;80mg(hydrochloride).

ComplementaryList

procainamide Injection:100mg(hydrochloride)/mlin10mlampoule.

quinidine Tablet:200mg(sulfate).

12.3 Antihypertensive medicines

amlodipine Tablet:5mg.

atenolol Tablet:50mg;100mg.

enalapril Tablet:2.5mg.

Powderforinjection:20mg(hydrochloride)inampoule.

Tablet:25mg,50mg(hydrochloride).

*Hydralazineislistedforuseintheacutemanagementofsevere
hydralazine*
pregnancyinducedhypertensiononly.Itsuseinthetreatmentof
essentialhypertensionisnotrecommendedinviewofthe
availabilityofmoreevidenceofefficacyandsafetyofother
medicines.

hydrochlorothiazide Tablet(scored):25mg.

 Tablet:250mg.

*Methyldopaislistedforuseinthemanagementof
methyldopa* pregnancyinducedhypertensiononly.Itsuseinthetreatmentof
essentialhypertensionisnotrecommendedinviewofthe
availabilityofmoreevidenceofefficacyandsafetyofother
medicines.

ComplementaryList

sodium
Powderforinfusion:50mginampoule.
nitroprusside

12.4 Medicines used in heart failure

ThissubsectionwillbereviewedatthenextmeetingoftheExpertCommittee.

Injection:250micrograms/mlin2mlampoule.

digoxin Oralliquid:50micrograms/ml.

Tablet:62.5micrograms;250micrograms.

enalapril Tablet:2.5mg.

Injection:10mg/mlin2mlampoule.
furosemide
Tablet:40mg.

Tablet(scored):25mg.
hydrochlorothiazide

ComplementaryList

dopamine Injection:40mg/ml(hydrochloride)in5mlvial.

dobutamine(T) 250mginj.

12.5 Antithrombotic medicines

acetylsalicylicacid Tablet:100mg.

ComplementaryList

streptokinase Powderforinjection:1.5millionIUinvial.

12.6 Lipid-lowering agents

Tablet:5mg;10mg;20mg;40mg.
simvastatin*
*Foruseinhighriskpatients.

13. DERMATOLOGICAL MEDICINES (topical)

13.1 Antifungal medicines

benzoicacid+salicylicacid Ointmentorcream:6%+3%.
miconazole Ointmentorcream:2%(nitrate).

sodiumthiosulfate Solution:15%.

ComplementaryList

seleniumsulfide Detergentbasedsuspension:2%.

13.2 Anti-infective medicines

methylrosaniliniumchloride(gentian Aqueoussolution:0.5%.
violet) Tincture:0.5%.

Ointment:5mgneomycinsulfate+250IU
neomycinsulfate+bacitracin
bacitracinzinc/g.

potassiumpermanganate Aqueoussolution:1:10000.

Cream:1%,in500gcontainer.
silversulfadiazine

13.3 Anti-inflammatory and antipruritic medicines

betamethasone Ointmentorcream:0.1%(asvalerate).

calaminelotion Lotion.

hydrocortisone Ointmentorcream:1%(acetate).

13.4 Astringent medicines

aluminiumdiacetate Solution:5%.

13.5 Medicines affecting skin differentiation and proliferation

benzoylperoxide Lotionorcream:5%.

coaltar Solution:5%.

dithranol Ointment:0.1%2%.

fluorouracil Ointment:5%.

podophyllumresin Solution:1025%.

salicylicacid Solution:5%.

urea Ointmentorcream:10%.

13.6 Scabicides and pediculicides

benzylbenzoate Lotion:25%.
 Cream:5%.
permethrin
Lotion:1%.

14. DIAGNOSTIC AGENTS

14.1 Ophthalmic medicines

fluorescein Eyedrops:1%(sodiumsalt).

tropicamide Eyedrops:0.5%.

14.2 Radiocontrast media

Injection:140420mgiodine(assodiumormegluminesalt)/ml
amidotrizoate
in20mlampoule.

bariumsulfate Aqueoussuspension.

Injection:140350mgiodine/mlin5ml;10ml;20ml
iohexol
ampoules.

ComplementaryList

meglumine
Solution:58giodinein100250ml.
iotroxate

15. DISINFECTANTS AND ANTISEPTICS

15.1 Antiseptics

chlorhexidine Solution:5%(digluconate)fordilution.

ethanol Solution:70%(denatured).

polyvidoneiodine Solution:10%.

15.2 Disinfectants

chlorinebase
Powder:(0.1%availablechlorine)forsolution.
compound

chloroxylenol Solution:4.8%.

glutaral Solution:2%.

16. DIURETICS
amiloride Tablet:5mg(hydrochloride).

Injection:10mg/mlin2mlampoule.
furosemide
Tablet:40mg.

hydrochlorothiazide Tablet(scored):25mg.

mannitol Injectablesolution:10%;20%.
spironolactone Tablet:25mg.

17. GASTROINTESTINAL MEDICINES

17.1 Antacids and other antiulcer medicines

aluminium Oralliquid:320mg/5ml.
hydroxide Tablet:500mg.

Injection:25mg/mlin2mlampoule.

ranitidine Oralliquid:75mg/5ml.

Tablet:150mg(ashydrochloride).

magnesium
Oralliquid:equivalentto550mgmagnesiumoxide/10ml.
hydroxide

Lactulose 3.5mg/5mlsyrup

Omeprazole 20mgcap.

17.2 Antiemetic medicines

Injection:5mg(hydrochloride)/mlin2mlampoule.
metoclopramide
Tablet:10mg(hydrochloride).

Injection:25mg(hydrochloride)/mlin2mlampoule.

promethazine Oralliquid:5mg(hydrochloride)/5ml.

Tablet:10mg;25mg(hydrochloride).

17.3 Anti-inflammatory medicines

Retentionenema.

sulfasalazine Suppository:500mg.

Tablet:500mg.

ComplementaryList

Retentionenema.
hydrocortisone
Suppository:25mg(acetate).(theonlyappliestohydrocortisone
retentionenema).

17.4 Laxatives

senna Tablet:7.5mg(sennosides)(ortraditionaldosageforms).

17.5 Medicines used in diarrhoea

17.5.1 Oral rehydration
 glucose:75mEqsodium:75mEqormmol/lchloride:65
mEqormmol/lpotassium:20mEqormmol/lcitrate:10
mmol/losmolarity:245mOsm/lglucose:13.5g/lsodium
chloride:2.6g/lpotassiumchloride:1.5g/ltrisodiumcitrate
dihydrate+:2.9g/l
oralrehydration
+trisodiumcitratedihydratemaybereplacedbysodiumhydrogen
salts*
carbonate(sodiumbicarbonate)2.5g/l.However,asthestability
ofthislatterformulationisverypoorundertropicalconditions,it
isonlyrecommendedwhenmanufacturedforimmediateuse.

*Incasesofcholeraahigherconcentrationofsodiummaybe
required.

17.5.2 Medicines for diarrhoea in children

Oralliquid:in10mgperunitdosageforms.

Tablet:in10mgperunitdosageforms.
zincsulfate*
*Inacutediarrhoeazincsulfateshouldbeusedasanadjunctto
oralrehydrationsalts.

17.5.3 Antidiarrhoeal (symptomatic) medicines in adults

Tablet:30mg(phosphate).
codeine*

18. HORMONES, OTHER ENDOCRINE MEDICINES AND

CONTRACEPTIVES
18.1 Adrenal hormones and synthetic substitutes

Addisonsdiseaseisararecondition;adrenalhormonesarealreadyincludedinsection
3.

18.1 Androgens

ComplementaryList

testosterone Injection:200mg(enantate)in1mlampoule.

18.2 Contraceptives
18.2.1 Oral hormonal contraceptives

ethinylestradiol+
Tablet:30micrograms+150micrograms.
levonorgestrel
ethinylestradiol+
Tablet:35micrograms+1.0mg.
norethisterone

levonorgestrel Tablet:30micrograms;750micrograms(packoftwo);1.5mg.

18.2.2 Injectable hormonal contraceptives

medroxyprogesteroneacetate
Depotinjection:150mg/mlin1mlvial.

medroxyprogesteroneacetate
Injection:25mg+5mg.
+estradiolcypionate

norethisteroneenantate Oilysolution:200mg/mlin1mlampoule.

18.2.3 Intrauterine devices

coppercontainingdevice

18.2.4 Barrier methods

condoms

diaphragms

18.2.5 Implantable contraceptives

Tworodlevonorgestrelreleasingimplant,eachrod
levonorgestrelreleasing containing75mgoflevonorgestrel(150mgtotal).
implant

18.3 Estrogens

Tablet:10micrograms;50micrograms.

*Thepublichealthrelevanceand/orcomparativeefficacy
ethinylestradiol* and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

18.4 Insulins and other antidiabetic agents

glibenclamide Tablet:2.5mg;5mg.

insulininjection(soluble) Injection:100IU/mlin10mlvial.

Injection:40IU/mlin10mlvial;100IU/mlin10mlvial
intermediateactinginsulin (ascompoundinsulinzincsuspensionorisophane
insulin).

Tablet:500mg(hydrochloride).
metformin

18.5 Ovulation inducers

 ComplementaryList

clomifene Tablet:50mg(citrate).

18.6 Progestogens

Tablet:5mg.

*Thepublichealthrelevanceand/orcomparativeefficacy
norethisterone* and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

ComplementaryList

Tablet:5mg.

medroxyprogesterone *Thepublichealthrelevanceand/orcomparativeefficacy
acetate* and/orsafetyofthisitemhasbeenquestionedandits
continuedinclusiononthelistwillbereviewedatthe
nextmeetingofthexpertCommittee.

18.7 Thyroid hormones and antithyroid medicines

levothyroxine Tablet:50micrograms;100micrograms(sodiumsalt).

potassiumiodide Tablet:60mg.

Tablet:50mg.
propylthiouracil

19. IMMUNOLOGICALS
19.1 Diagnostic agents

tuberculin,purifiedprotein
Injection.
derivative(PPD)

19.2 Sera and immunoglobulins

AllplasmafractionsshouldcomplywiththeWHORequirementsfortheCollection,
ProcessingandQualityControlofBlood,BloodComponentsandPlasmaDerivatives.

antiDimmunoglobulin
Injection:250microgramsinsingledosevial.
(human)

antitetanusimmunoglobulin
Injection:500IUinvial.
(human)

Injection.
antivenomimmunoglobulin*
*Exacttypetobedefinedlocally.

diphtheriaantitoxin Injection:10000IU;20000IUinvial.
rabiesimmunoglobulin Injection:150IU/mlinvial.

AntihepatitisB injectin.

immunoglobulin

19.3 Vaccines
Vaccine for Universal Immunization

BCG(dried)vaccine inj

diptheriapertussistetanus inj.

vaccine

dipatheriatetanusvaccine inj.

measlesmumpsrubella

vaccine inj.

measlesvaccine inj.

poliomyelitisvaccine oralsolution,liveattenuated

tetanusvaccine inj.

Haemophilus influenzae inj.

type B vaccine

Rota virus vaccine inj.

Typhoid Vaccines inj.

VaccinesforSpecificUse.

Hepatitis A vaccine inj

hepatitisBvaccine inj.

meningococcalvaccine inj.

rabiesvaccine inj.

rubellavaccine inj

Cholera Vaccines inj

Flu vaccine (influenza) inj

Pneumococcal vaccine inj

20. MUSCLE RELAXANTS (PERIPHERALLY-ACTING) AND
CHOLINESTERASE INHIBITORS

alcuronium Injection:5mg(chloride)/mlin2mlampoule.

Injection:500microgramsin1mlampoule;2.5mg(metilsulfate)
neostigmine in1mlampoule.

Tablet:15mg(bromide).

Injection:50mg(chloride)/mlin2mlampoule.
suxamethonium
Powderforinjection(chloride)invial.

ComplementaryList

Injection:1mgin1mlampoule.
pyridostigmine
Tablet:60mg(bromide).

vecuronium Powderforinjection:10mg(bromide)invial.

21. OPHTHALMOLOGICAL PREPARATIONS

ThissectionwillbereviewedatthenextmeetingoftheExpertCommittee.

21.1 Anti-infective agents

aciclovir Ointment:3%W/W.

Solution(eyedrops):0.3%(sulfate).
gentamicin*
*Finalselectiondependsonindicationforuse.

tetracycline Eyeointment:1%(hydrochloride).

21.2 Anti-inflammatory agents

prednisolone Solution(eyedrops):0.5%(sodiumphosphate).

21.3 Local anaesthetics

tetracaine Solution(eyedrops):0.5%(hydrochloride).

21.4 Miotics and antiglaucoma medicines

acetazolamide Tablet:250mg.

pilocarpine Solution(eyedrops):2%;4%(hydrochlorideornitrate).

timolol Solution(eyedrops):0.25%;0.5%(asmaleate).

21.5 Mydriatics

atropine Solution(eyedrops):0.1%;0.5%,1%(sulfate).

ComplementaryList
 epinephrine(adrenaline) Solution(eyedrops):2%(ashydrochloride).

22. OXYTOCICS AND ANTIOXYTOCICS

22.1 Oxytocics

Injection:200micrograms(hydrogenmaleate)in1ml
ergometrine
ampoule.

oxytocin Injection:10IUin1mlampoule.

22.2 Antioxytocics (tocolytics)

nifedipine Immediatereleasecapsule:10mg.

23. PERITONEAL DIALYSIS SOLUTION

ComplementaryList

intraperitonealdialysis
solution(ofappropriate Parenteralsolution.
composition)

24. PSYCHOTHERAPEUTIC MEDICINES

24.1 Medicines used in psychotic disorders

Injection:25mg(hydrochloride)/mlin2mlampoule.

chlorpromazine Oralliquid:25mg(hydrochloride)/5ml.

Tablet:100mg(hydrochloride).

Injection:25mg(decanoateorenantate)in1ml
fluphenazine
ampoule.

Injection:5mgin1mlampoule.

haloperidol Tablet:2mg;5mg.

24.2 Medicines used in mood disorders

24.2.1 Medicines used in depressive disorders

amitriptyline Tablet:25mg(hydrochloride).

fluoxetine Capsuleortablet:20mg(presentashydrochloride).

24.2.2 Medicines used in bipolar disorders

carbamazepine Tablet(scored):100mg;200mg.

lithiumcarbonate Capsuleortablet:300mg.
 Tablet(entericcoated):200mg;500mg(sodium
valproicacid
valproate).

Risperidone 1mg,2mg,3mgtab.

24.3 Medicines used in generalized anxiety and sleep disorders

diazepam Tablet(scored):2mg;5mg.

24.4 Medicines used for obsessive compulsive disorders and panic attacks

clomipramine Capsule:10mg;25mg(hydrochloride).

24.5 Medicines used in substance dependence programmes

ComplementaryList

Concentratefororalliquid:5mg/ml;10mg/ml
(hydrochloride).

Oralliquid:5mg/5ml;10mg/5ml.
methadone*
*Thesquareboxisaddedtoincludebuprenorphine.The
medicinesshouldonlybeusedwithinanestablished
supportprogramme.

25. MEDICINES ACTING ON THE RESPIRATORY TRACT

25.1 Antiasthmatic and medicines for chronic obstructive pulmonary
disease

Inhalation(aerosol):50microgramsperdose
beclometasone (dipropionate);250micrograms(dipropionate)per
dose.
Injection:1mg(ashydrochlorideorhydrogen
epinephrine(adrenaline)
tartrate)in1mlampoule.

ipratropiumbromide Inhalation(aerosol):20micrograms/metereddose.

Inhalation (aerosol): 100 micrograms (as sulfate) per

dose.
Injection: 50 micrograms (as sulfate)/ml in 5ml
ampoule.
salbutamol
Oralliquid:2mg/5ml.
Respirator solution for use in nebulizers: 5 mg (as
sulfate)/ml.
Tablet:2mg;4mg(assulfate).

25.2 Other medicines acting on the respiratory tract

aminophylline 100 & 200 mg tab. 250 mg inj.

theophylline 180 & 270 mg tab. 350 mg tab.

(S.R) 120 mg/5ml syrup.
26. SOLUTIONS CORRECTING WATER, ELECTROLYTE AND ACID-
BASE DISTURBANCES
26.1 Oral

oralrehydrationsalts Seesection17.5.1.

potassiumchloride Powderforsolution.

26.2 Parenteral

glucose Injectablesolution:5%;10%isotonic;50%hypertonic.

glucosewithsodium Injectablesolution:4%glucose,0.18%sodiumchloride
+
chloride (equivalenttoNa 30mmol/l,Cl30mmol/l).
+
Solution:11.2%in20mlampoule(equivalenttoK 1.5
potassiumchloride
mmol/ml,Cl 1.5mmol/ml).
+
Injectablesolution:0.9%isotonic(equivalenttoNa 154
sodiumchloride
mmol/l,Cl154mmol/l.
+
Injectablesolution:1.4%isotonic(equivalenttoNa 167
mmol/l,HCO3167mmol/l).
sodiumhydrogen
carbonate +
Solution:8.4%in10mlampoule(equivalenttoNa 1000
mmol/l,HCO31000mmol/l).

sodiumlactate,
Injectablesolution.
compoundsolution

26.3 Miscellaneous

2ml;5ml;10mlampoules.

waterforinjection

27. VITAMINS AND MINERALS

ascorbicacid Tablet:50mg.

Capsuleortablet:1.25mg(50000IU).
ergocalciferol
Oralliquid:250micrograms/ml(10000IU/ml).
 Capsule:200mg.

iodine Iodizedoil:1ml(480mgiodine);0.5ml(240mgiodine)in
ampoule(oralorinjectable);0.57ml(308mgiodine)in
dispenserbottle.

nicotinamide Tablet:50mg.

pyridoxine Tablet:25mg(hydrochloride).

Capsule:50000IU;100000IU;200000IU(aspalmitate).

Oraloilysolution:100000IU(aspalmitate)/mlinmultidose
dispenser.
retinol
Tablet(sugarcoated):10000IU(aspalmitate).

Watermiscibleinjection:100000IU(aspalmitate)in2ml
ampoule.

riboflavin Tablet:5mg.

sodiumfluoride Inanyappropriatetopicalformulation.

thiamine Tablet:50mg(hydrochloride).

ComplementaryList

calciumgluconate Injection:100mg/mlin10mlampoule.
 INDEX

Abacavir(ABC)..........................................................
Acetazolamide..........................................................
Acetylcysteine............................................................
Acetylsalicylicacid.................................................
Aciclovir....................................................................
Albendazole................................................................
Alcuronium...............................................................
Allopurinol.................................................................
Aluminiumdiacetate...............................................
Aluminiumhydroxide............................................
Amidotrizoate..........................................................
Amikacin......................................................................
Amiloride..................................................................
Aminophylline
Amitriptyline............................................................
Amlodipine...............................................................
Amodiaquine............................................................
Amoxicillin.................................................................
Amoxicillin+clavulanicacid..................................
AmphotericinB............................................................
Ampicillin...................................................................
AntiDimmunoglobulin(human).........................
AntiHepatitisBImmunoglobulin..
Antitetanusimmunoglobulin(human).................
Antivenomimmunoglobulin.................................
Artemether................................................................
Artemether+lumefantrine.....................................
Artesunate.................................................................
Ascorbicacid............................................................
Asparaginase...............................................................
Atenolol......................................................................
Atropine......................................................................
Azathioprine................................................................
Azithromycin..............................................................
Bacitracin..................................................................
Bariumsulfate.........................................................
BCG(dried)vaccine.
Beclometasone.........................................................
Benzathinebenzylpenicillin....................................
Benznidazole............................................................
Benzoicacid.............................................................
Benzoicacid+salicylicacid...................................
Benzoylperoxide.....................................................
Benzylbenzoate.......................................................
Benzylpenicillin.........................................................
Betamethasone.........................................................
Bleomycin...................................................................
Bupivacaine................................................................
Calaminelotion........................................................
Calciumfolinate..........................................................
Calciumgluconate....................................................
Capreomycin.................................................................
Carbamazepine..........................................................
Carbidopa..................................................................
Cefazolin......................................................................
Cefixime.......................................................................
Ceftazidime...................................................................
Ceftriaxone....................................................................
Charcoal,activated.....................................................
Chlorambucil..................................................................
Chloramphenicol........................................................
Chlorhexidine.............................................................
Chlorinebasecompound........................................
Chloroquine...................................................................
Chloroxylenol...........................................................
Chlorphenamine.........................................................
Chlorpromazine.......................................................
CholeraVaccine
Ciclosporin.................................................................
Cilastatin......................................................................
Ciprofloxacin..............................................................
Cisplatin......................................................................
Clavulanicacid...........................................................
Clindamycin.................................................................
Clofazimine.................................................................
Clomifene....................................................................
Clomipramine...........................................................
Clotrimazole...............................................................
Cloxacillin...................................................................
Coaltar......................................................................
Codeine.......................................................................
Condoms...................................................................
Coppercontainingdevice.......................................
Cyclophosphamide......................................................
Cycloserine....................................................................
Cytarabine...................................................................
Dacarbazine................................................................
Dactinomycin..............................................................
Dapsone......................................................................
Daunorubicin..............................................................
Deferoxamine.............................................................
Dexamethasone.........................................................
Dextran70.................................................................
Diaphragms..............................................................
Diazepam...................................................................
Didanosine(ddi)........................................................
Digoxin..........................................................................
Diloxanide.................................................................
Dimercaprol................................................................
Diphtheriaantitoxin................................................
Diptheriapertussistetanusvaccine
Dipatheriatetanusvaccine.
Dithranol...................................................................
DLmethionine..........................................................
Dobutamine..
Dopamine....................................................................
Doxorubicin................................................................
Doxycycline.................................................................
Efavirenz..........................................................................
Efavirenz+emtricitabine+tenofovir...................
Eflornithine..............................................................
Emtricitabine........................................................
Emtricitabine+tenofovir........................................
Enalapril...................................................................
Ephedrine......................................................................
Epinephrine(adrenaline)........................................
Ergocalciferol...........................................................
Ergometrine..............................................................
Erythromycin.............................................................
Estradiolcypionate..................................................
Ethambutol................................................................
Ethanol......................................................................
Ethinylestradiol............................................................
Ethinylestradiol+levonorgestrel..........................
Ethinylestradiol+norethisterone..........................
Ethionamide..................................................................
Ethosuximide................................................................
Etoposide....................................................................
FactorIXcomplex(coagulationfactors,II,VII,IX,X)oncentrate........
FactorVIIIconcentrate...............................................
Ferroussalt...............................................................
Ferroussalt+folicacid...........................................
Fluconazole.................................................................
Flucytosine....................................................................
Fluorescein................................................................
Fluorouracil..................................................................
Fluoxetine.................................................................
Fluphenazine............................................................
Fluvaccine(influenza)
Folicacid......................................................................
Furosemide...................................................................
Gentamicin...................................................................
Gentianviolet...........................................................
Glibenclamide..........................................................
Glucose......................................................................
Glutaral......................................................................
Glyceryltrinitrate.....................................................
Griseofulvin.................................................................
HaemophilusinfluenzaetypeBvaccine..
Haloperidol................................................................
Halothane.....................................................................
HepatitisAvaccine
HepatitisBvaccine.
Heparinsodium........................................................
Humannormalimmunoglobulin................................
Hydralazine..............................................................
Hydrochlorothiazide....................................................
Hydrocortisone.................................................................
Hydroxocobalamin..................................................
Ibuprofen....................................................................
Imipenem+cilastatin...................................................
Immunoglobulin..............................................................
Indinavir(IDV).....................................................................
Insulininjection(soluble)................................................
Intermediateactinginsulin..............................................
Intraperitonealdialysissolution(ofappropriatecomposition)..........................................................
Iodine..................................................................
Iohexol......................................................................
Ipratropiumbromide..............................................
Isoniazid.....................................................................
Isoniazid+ethambutol.............................................
Isosorbidedinitrate.................................................
Ivermectin..................................................................
Kanamycin....................................................................
Ketamine.....................................................................
Lactulose
Lamivudine.................................................................
Lamivudine(3TC)......................................................
Levamisole.................................................................
Levodopa...................................................................
Levodopa+carbidopa.............................................
Levonorgestrel............................................................
Levonorgestrelreleasingimplant..........................
Levothyroxine...........................................................
Lidocaine...............................................................
Lidocaine+epinephrine(adrenaline)......................
Lithiumcarbonate....................................................
Lopinavir...................................................................
Lopinavir+ritonavir(LPV/r)..................................
Lumefantrine............................................................
Magnesiumhydroxide...........................................
Magnesiumsulfate....................................................
Mannitol...................................................................
Measlesmumpsrubellavaccine..
Measlesvaccine.
Mebendazole..............................................................
Medroxyprogesteroneacetate.........................
Medroxyprogesteroneacetate+estradiolcypionate.............................................................
Mefloquine..............................................................
Meglumineiotroxate..................................................
Melarsoprol..............................................................
Meningococcalvaccine.
Mercaptopurine..........................................................
Metformin................................................................
Methadone..................................................................
Methotrexate...............................................................
Methyldopa..............................................................
Methyleneblue..........................................................
Methylrosaniliniumchloride(gentianviolet)............
Methylthioniniumchloride(methyleneblue)............
Metoclopramide......................................................
Metronidazole.........................................................
Miconazole...............................................................
Morphine...................................................................
Nalidixicacid..
Naloxone.....................................................................
Nelfinavir(NFV)......................................................
Neomycinsulfate.....................................................
Neomycinsulfate+bacitracin................................
Neostigmine.............................................................
Nevirapine................................................................
Niclosamide................................................................
Nicotinamide............................................................
Nifedipine.................................................................
Nifurtimox................................................................
Nitrofurantoin............................................................
Nitrousoxide..............................................................
Norethisterone.............................................................
Nystatin.........................................................................
Ofloxacin..........................................................................
Omeprazole
Oralrehydrationsalts............................................
Oxygen........................................................................
Oxytocin....................................................................
Paminosalicylicacid...................................................
Paracetamol................................................................
Penicillamine................................................................
Permethrin...............................................................
Pethidine
Phenobarbital............................................................
Phenoxymethylpenicillin.........................................
Phenytoin...................................................................
Phytomenadione.....................................................
Pilocarpine...............................................................
Pneumococcalvaccine.
Podophyllumresin.................................................
Poliomyelitisvaccineoralsolution(liveattenuated).
Polyvidoneiodine...................................................
Potassiumchloride....................................................
Potassiumferrichexacyanoferrate(II)2H20(Prussianblue)......................................................
Potassiumiodide..........................................................
Potassiumpermanganate.......................................
Prednisolone............................................................
Primaquine...............................................................
Procainamide..............................................................
Procainebenzylpenicillin.........................................
Procarbazine...............................................................
Procyclidine
Proguanil..................................................................
Promethazine............................................................
Propranolol..............................................................
Propylthiouracil......................................................
Protaminesulfate....................................................
Prussianblue.............................................................
Pyrantel......................................................................
Pyrazinamide.............................................................
Pyridostigmine..............................................................
Pyridoxine...................................................................
Pyrimethamine..........................................................
Quinidine.......................................................................
Quinine.........................................................................
Rabiesimmunoglobulin............................................
Rabiesvaccine
Ranitidine.....................................................................
Retinol...........................................................................
Ribavirin....................................................................
Riboflavin..................................................................
Rifampicin...................................................................
Rifampicin+isoniazid...............................................
Rifampicin+isoniazid+ethambutol.......................
Rifampicin+isoniazid+pyrazinamide..................
Rifampicin+isoniazid+pyrazinamide+ethambutol............................................................
Risperidone
Ritonavir....................................................................
Rotavirusvaccine.
Rubellavaccine
Salbutamol................................................................
Salicylicacid.............................................................
Saquinavir(SQV).....................................................
Seleniumsulfide.........................................................
Senna.........................................................................
Silversulfadiazine...................................................
Simvastatin...............................................................
Sodiumcalciumedetate............................................
Sodiumchloride...........................................................
Sodiumfluoride.......................................................
Sodiumhydrogencarbonate.................................
Sodiumlactate..........................................................
Sodiumnitrite............................................................
Sodiumnitroprusside....................................................
Sodiumstibogluconate
Sodiumthiosulfate...................................................
Sodiumvalproate.....................................................
Spectinomycin...........................................................
Spironolactone.........................................................
Stavudine..............................................................
Stavudine+lamivudine+nevirapine...................
Streptokinase..............................................................
Streptomycin..............................................................
Sulfadiazine..................................................................
Sulfadoxine...............................................................
Sulfadoxine+pyrimethamine...............................
Sulfamethoxazole......................................................
Sulfamethoxazole+trimethoprim......................
Sulfasalazine...........................................................
Suxamethonium......................................................
Tamoxifen...................................................................
Tenofovirdisoproxilfumarate.............................
Testosterone................................................................
Tetanusvaccine..
Tetracaine..................................................................
Tetracycline...............................................................
Theophylline.
Thiamine...................................................................
Thiopental...................................................................
Timolol.......................................................................
Trimethoprim.............................................................
Tropicamide..............................................................
TyphoidVaccines.
Tuberculin,purifiedproteinderivative(PPD)..........
Urea...........................................................................
Valproicacid.........................................................
Vancomycin..................................................................
Vecuronium................................................................
Verapamil.................................................................
Vinblastine..................................................................
Vincristine..................................................................
Warfarin....................................................................
Waterforinjection...................................................
Yellowfevervaccine
Zidovudine...........................................................
Zidovudine+lamivudine.......................................
Zidovudine+lamivudine+nevirapine................
Zincsulfate...............................................................