Service Manual
2008-2012 Shenzhen Mindray Bio-medical Electronics Co., Ltd. All rights
Reserved.
For this Service Manual, the issued Date is 2012-12 (Version: 5.0).
, , , , , are the
registered trademarks or trademarks owned by Mindray in China and other countries.
All other trademarks that appear in this manual are used only for editorial purposes
without the intention of improperly using them. They are the property of their
respective owners.
All information contained in this manual is believed to be correct. Mindray shall not be
liable for errors contained herein nor for incidental or consequential damages in
connection with the furnishing, performance, or use of this manual.
Mindray is responsible for safety, reliability and performance of this product only in
the condition that:
the electrical installation of the relevant room complies with the applicable
national and local requirements;
Upon request, Mindray may provide, with compensation, necessary circuit diagrams,
calibration illustration list and other information to help qualified technician to maintain
and repair some parts, which Mindray may define as user serviceable.
i
WARNING:
NOTE:
Warranty
THIS WARRANTY IS EXCLUSIVE AND IS IN LIEU OF ALL OTHER WARRANTIES,
EXPRESSED OR IMPLIED, INCLUDING WARRANTIES OF MERCHANTABILITY
OR FITNESS FOR ANY PARTICULAR PURPOSE.
Exemptions
Mindray's obligation or liability under this warranty does not include any
transportation or other charges or liability for direct, indirect or consequential
damages or delay resulting from the improper use or application of the product or the
use of parts or accessories not approved by Mindray or repairs by people other than
Mindray authorized personnel.
any Mindray product from which Mindray's original serial number tag or product
identification markings have been altered or removed;
Return Policy
Return Procedure
In the event that it becomes necessary to return this product or part of this product to
Mindray, the following procedure should be followed:
Obtain return authorization: Contact the Mindray Service Department and obtain
a Customer Service Authorization (Mindray) number. The Mindray number must
appear on the outside of the shipping container. Returned shipments will not be
accepted if the Mindray number is not clearly visible. Please provide the model
number, serial number, and a brief description of the reason for return.
Freight policy: The customer is responsible for freight charges when this product
is shipped to Mindray for service (this includes customs charges).
Return address: Please send the part(s) or equipment to the address offered by
Customer Service department.
ii
Company Contact
Manufacturer: Shenzhen Mindray Bio-Medical Electronics Co.,
Ltd.
Address: Mindray Building,Keji 12th Road South,High-tech
industrial park,Nanshan,Shenzhen
518057,P.R.China
Website: www.mindray.com
E-mail Address: service@mindray.com
Tel: +86 755 81888998
Fax: +86 755 26582680
EC Representative
Name: Shanghai International Holding Corp. GmbH (Europe)
Address: Eiffestrasse 80 D-20537 Hamburg Germany
Tel: +49 40 2513174
Fax: +49 40 255726
iii
iv
Preface
Who Should Read This Manual
This manual is geared for service personnel authorized by Mindray.
Bold and Italic font indicates text displayed on the screen, such as Sample Request.
Safety Symbols
Preface 1
Serial Number
Date of Manufacture
Manufacturer
ON (Main Power)
ON (Power)
OFF (Power)
HIGH CONC.
High-concentration waste
WASTE
HIGH CONC.
High-concentration waste sensor
WASTE SENSOR
2 Preface
LOW CONC.
High-pressure low-concentration waste
WASTE 1
LOW CONC.
Normal-pressure low-concentration waste
WASTE 2
WASH
Wash solution
SOLUTION
WASH
SOLUTION Wash solution sensor
SENSOR
DEIONIZED
Deionized water
WATER
Model:
Product model
BS-380/BS-390
Graphics
All graphics, including screens and printout, are for illustration purposes only and must
not be used for any other purpose.
Preface 3
Safety Precautions
Observe the following safety precautions when using the BS-380/BS-390 Chemistry
Analyzer. Ignoring any of these safety precautions may lead to personal injury or
equipment damage.
WARNING:
If the system is used in a manner not specified by Mindray, the
protection provided by the system may be impaired.
WARNING:
When the Main Power is on, users must not open the back cover or side
cover.
Spillage of reagent or sample on the analyzer may cause equipment
failure and even electric shock. Do not place sample and reagent on the
analyzer. In case of spillage, switch off the power immediately, remove
the spillage.
WARNING:
Do not touch such moving parts as sample probe, reagent probe, mixer
and wash probe, when the system is in operation.
Do not touch the sample probe or mixer while the system is in operation.
Make sure the reagent disk cover is properly installed.
WARNING:
Light sent by the photometer lamp may hurt your eyes. Do not stare
into the lamp when the system is in operation.
If you want to replace the photometer lamp, first switch off the lamp
and then wait at least 15 minutes for the lamp to cool down before
touching it. Do not touch the lamp before it cools down, or you may get
burned.
4 Preface
Preventing Laser Radiation
Please observe the following instructions to prevent personal injury caused by laser
radiation.
CAUTION:
Light sent by the bar code reader may hurt your eyes. Do not stare into
the laser beam from the bar code reader.
Preventing Infection
Please observe the following instructions to protect against the biohazardous infection.
BIOHAZARD:
Inappropriately handling samples, controls and calibrators may lead to
biohazardous infection. Do not touch the sample, mixture or waste with
your hands. Wear gloves and lab coat and, if necessary, goggles.
In case your skin contacts the sample, control or calibrator, follow
standard laboratory safety procedure and consult a doctor.
WARNING:
Reagents, concentrated wash solution and enhanced wash solution
are corrosive to human skins. Exercise caution when using the
reagents, concentrated wash solution and enhanced wash solution. In
case your skin or clothes contact the reagents or wash solution, wash
them off with soap and clean water. In case the reagents or wash
solution spill into your eyes, rinse them with much water and consult an
oculist.
BIOHAZARD:
Some substances in reagent, control, enhanced wash solution and
waste are subject to regulations of contamination and disposal. Dispose
of them in accordance with your local or national guidelines for
biohazard waste disposal and consult the manufacturer or distributor of
the reagents for details.
Wear gloves and lab coat and, if necessary, goggles.
Preface 5
WARNING:
Materials of the analyzer are subject to contamination regulations.
Dispose of the waste analyzer in accordance with your local or national
guidelines for waste disposal.
WARNING:
Ethanol is flammable substance. Please exercise caution while using the
ethanol.
6 Preface
Precautions on Use
To use the BS-380/BS-390 Chemistry Analyzer safely and efficiently, please pay much
attention to the following operation notes.
Intended Use
WARNING:
The BS-380/BS-390 is a fully-automated and computer-controlled
chemistry analyzer designed for in vitro quantitative determination of
clinical chemistries in serum, plasma, urine and CSF samples. Please
consult Mindray first if you want to use the system for other purposes.
To draw a clinical conclusion, please also refer to the patients clinical
symptoms and other test results.
Operator
WARNING:
The BS-380/BS-390 is to be operated only by clinical professionals,
doctors or laboratory experimenters trained by Mindray or
Mindray-authorized distributors.
Environment
CAUTION:
Please install and operate the system in an environment specified by
this manual. Installing and operating the system in other environment
may lead to unreliable results and even equipment damage.
Preface 7
Preventing Interference by Electromagnetic Noise
CAUTION:
Electromagnetic noise may interfere with operations of the system. Do
not install devices generating excessive electromagnetic noise around
the system. Do not use such devices as mobile phones or radio
transmitters in the room housing the system. Do not use other CRT
displays around the system.
Do not use other medical instruments around the system that may
generate electromagnetic noise to interfere with their operations.
Do not use this device in close proximity to sources of strong
electromagnetic radiation (e.g. mobile phones or radio transmitters), as
these may interfere with the proper operation.
The electromagnetic environment should be evaluated prior to operation
of the device.
This device has been designed and tested to CISPR 11 Class A, and in
a domestic environment may cause radio interference, in which case,
you may need to take measures to mitigate the interference.
CAUTION:
Operate the system strictly as instructed by this manual. Inappropriate
use of the system may lead to unreliable test results or even equipment
damage or personal injury.
Before using the system for the first time, run the calibration program
and QC program to make sure the system is in proper status.
Be sure to run the QC program every time you use the system,
otherwise the result may be unreliable.
Do not open the covers of the sample disk and reagent disk when the
system is in operation.
The RS-232 port on the analyzing unit is to be used for connection with
the operation unit only. Do not use it for other connections. Only use the
supplied cable for the connection.
The operation unit is a personal computer with the BS-380/BS-390
operating software installed. Installing other software or hardware on this
computer may interfere with the system operation. Do not run other
software when the system is working.
Computer virus may destroy the operating software or test data. Do not
use this computer for other purposes or connect it to the Internet. If the
computer is infected by virus, please install anti-virus software to check
for and clear virus.
Do not touch the display, mouse or keyboard with wet hands or hands
with chemicals.
Do not place the Main Power to ON again within 10 seconds since
placing it to OFF; otherwise the system may enter protection status. If it
does so, switch off the Main Power and switch it on again.
8 Preface
Maintaining the System
CAUTION:
Maintain the system strictly as instructed by this manual. Inappropriate
maintenance may lead to unreliable results, or even equipment damage
and personal injury.
To wipe off dust from the system surface, use a soft, clean and wet (not
too wet) cloth, soaked with mild soap solution if necessary, to clean the
surface. Do not use such organic solvents as ethanol for cleaning. After
cleaning, wipe the surface with dry cloth.
Switch off all the powers and unplug the power cord before cleaning.
Take necessary measures to prevent water ingression into the system,
otherwise it may lead to equipment damage or personal injury.
Replacement of such major parts as lamp, photometer, sample probe,
reagent probe, mixer and syringe plunger assembly must be followed by
a calibration.
Samples
CAUTION:
Use samples that are completely free of insoluble substances like fibrin,
or suspended matter; otherwise the probe may be blocked.
Medicines, anticoagulants or preservative in the samples may lead to
unreliable results.
Hemolysis, icterus or lipemia in the samples may lead to unreliable test
results, so a sample blank is recommended.
Store the samples properly. Improper storage may change the
compositions of the samples and lead to unreliable results.
Sample volatilization may lead to unreliable results. Do not leave the
sample open for a long period.
Some samples may not be analyzed on the BS-380/BS-390 based on
parameters the reagents claim capable of testing. Consult the reagent
manufacturer or distributor for details.
Certain samples need to be processed before being analyzed by the
system. Consult the reagent manufacturer or distributor for details.
The system has specific requirements on the sample volume. Refer to
this manual for details.
Load the sample to correct position on the sample disk before the
analysis begins; otherwise you will not obtain correct results.
CAUTION:
To define such parameters as sample volume, reagent volume and
wavelength, follow the instructions in this manual and the package insert
of the reagents.
Preface 9
Reagents, Calibrators and Controls
CAUTION:
Use appropriate reagents, calibrators and controls on the system.
Select appropriate reagents according to performance characteristic of
the system. Consult the reagent suppliers, Mindray or
Mindray-authorized distributor for details, if you are not sure about your
reagent choice.
Store and use reagents, calibrators and controls strictly as instructed by
the suppliers. Otherwise, you may not obtain reliable results or best
performance of the system.
Improper storage of reagents, calibrators and controls may lead to
unreliable results and bad performance of the system even in validity
period.
Perform a calibration after changing reagents. Otherwise, you may not
obtain reliable results.
Contamination caused by carryover among reagents may lead to
unreliable test results. Consult the reagent manufacturer or distributor
for details.
Backing up Data
NOTE:
The system can automatically store data to the built-in hard disk of the
PC. However, data loss is still possible due to mis-deletion or physical
damage of the hard disk. Mindray recommends you to regularly back up
the data to portable storage device.
NOTE:
Refer to the operation manuals of computer and printer for details.
External Equipment
WARNING:
Accessory equipment connected to the analogue and digital interfaces
must be complied with the relevant Safety and EMC standards (e.g., IEC
60950 Safety of Information Technology Equipment Standard and CISPR
22 EMC of Information Technology Equipment Standard (CLASS B)).
Any person, who connects additional equipment to the signal input or
output ports and configures an IVD system, is responsible for ensuring
that the system work normally and complies with the safety and EMC
requirements. If you have any problem, consult the technical services
department of your local representative.
10 Preface
Contents
Warranty .............................................................................................................................. ii
Return Policy ....................................................................................................................... ii
Preface .............................................................................................................. 1
Who Should Read This Manual .......................................................................................... 1
What Can You Find in This Manual .................................................................................... 1
Conventions Used in This Manual ...................................................................................... 1
Safety Precautions ............................................................................................................. 4
Precautions on Use ............................................................................................................ 7
Contents ............................................................................................................. I
1 System Description .............................................................................. 1-1
1.1 Overview ............................................................................................................... 1-1
1.2 System Components ............................................................................................ 1-2
1.3 Functions .............................................................................................................. 1-2
2 System Performance and Workflow ................................................... 2-1
2.1 Technical Specifications ........................................................................................ 2-1
2.1.1 General .................................................................................................... 2-1
2.1.2 Specifications for Sample System ........................................................... 2-2
2.1.3 Specifications for Reagent System .......................................................... 2-4
2.1.4 Specifications of Reaction System .......................................................... 2-5
2.1.5 Specifications of Operation ...................................................................... 2-6
2.1.6 Installation Requirements ........................................................................ 2-6
2.1.7 Optional Modules ..................................................................................... 2-7
2.2 Timing Principle .................................................................................................... 2-7
2.2.1 Overview .................................................................................................. 2-7
2.2.2 Timing ...................................................................................................... 2-7
2.2.3 Measuring Points ..................................................................................... 2-9
3 Installation Procedures ........................................................................ 3-1
3.1 Environmental Requirements ............................................................................... 3-1
3.2 Installation Requirements ..................................................................................... 3-2
3.2.1 Space and Accessibility Requirements .................................................... 3-2
3.2.2 Power Requirements ............................................................................... 3-2
3.2.3 Water Supply and Drainage Requirements ............................................. 3-3
3.2.4 Connecting Water Supply and Drain Facilities ........................................ 3-5
3.2.5 Connecting Water Treatment System ...................................................... 3-7
3.3 Installation Procedures ......................................................................................... 3-7
3.3.1 Tools......................................................................................................... 3-7
3.3.2 Unpacking ................................................................................................ 3-7
3.3.3 Installing the Instrument......................................................................... 3-10
3.3.4 Installing ISE Module (Optional) ............................................................ 3-14
3.4 Startup Testing .................................................................................................... 3-16
3.4.1 Startup Initialization ................................................................................ 3-18
3.4.2 Checking Cuvette & Lamp ..................................................................... 3-19
3.4.3 System Set up & Test ............................................................................ 3-19
Contents I
3.4.4 Checking Low Concentration Waste Drainage ...................................... 3-20
3.4.5 Exiting Software ..................................................................................... 3-20
4 Units and Modules................................................................................ 4-1
4.1 Enclosure .............................................................................................................. 4-1
4.1.1 Components............................................................................................. 4-1
4.1.2 Remove and Install Enclosure ................................................................. 4-2
4.1.3 Remove and Install Side Plate................................................................. 4-2
4.1.4 Remove and Install Panel ........................................................................ 4-3
4.2 Sample/Reagent Probe Unit ................................................................................. 4-4
4.2.1 Introduction .............................................................................................. 4-4
4.2.2 Components and Structure ...................................................................... 4-5
4.2.3 Installation ................................................................................................ 4-6
4.3 Mixer Unit .............................................................................................................. 4-7
4.3.1 Introduction .............................................................................................. 4-7
4.3.2 Components and Structure ...................................................................... 4-7
4.3.3 Installation ................................................................................................ 4-9
4.4 Sample Disk Unit ................................................................................................ 4-10
4.4.1 Introduction ............................................................................................ 4-10
4.4.2 Components and Structure .................................................................... 4-10
4.4.3 Servicing ................................................................................................ 4-11
4.5 Reagent Disk Unit ............................................................................................... 4-13
4.5.1 Introduction ............................................................................................ 4-13
4.5.2 Components and Structure .................................................................... 4-14
4.5.3 Servicing the Reagent Disk Unit ............................................................ 4-15
4.6 Reaction Disk Unit .............................................................................................. 4-20
4.6.1 Introduction ............................................................................................ 4-20
4.6.2 Components and Structure .................................................................... 4-21
4.6.3 Replacing Components and Parts ......................................................... 4-22
4.7 Photometric Unit ................................................................................................. 4-29
4.7.1 Introduction ............................................................................................ 4-29
4.7.2 Components and Structure .................................................................... 4-29
4.7.3 Adjustment of Photometer ..................................................................... 4-32
4.7.4 Replacing Optical Assembly .................................................................. 4-38
4.8 Wash Unit ........................................................................................................... 4-38
4.8.1 Install and Service the Wash Assembly ................................................. 4-40
4.8.2 Install and Service the Wash Probe Syringe Assembly ......................... 4-40
4.8.3 Install and Service the Wash Preheat Assembly ................................... 4-40
4.9 ISE Unit (optional)............................................................................................... 4-40
4.9.1 Components and Structure .................................................................... 4-41
4.9.2 Install and Remove ISE unit .................................................................. 4-41
5 Hydropneumatic System ..................................................................... 5-1
5.1 Introduction ........................................................................................................... 5-1
5.2 Function Block Diagram ....................................................................................... 5-2
5.3 Schematic Diagram of Fluidic System .................................................................. 5-3
5.4 Layout of Fluidic System ...................................................................................... 5-3
5.5 Layout of Fluidic System ...................................................................................... 5-4
5.6 Connectors and Tubing ........................................................................................ 5-5
6 Hardware ............................................................................................... 6-1
6.1 Overview ............................................................................................................... 6-1
6.2 Safety Precautions................................................................................................ 6-1
II Contents
6.3 Circuit boards ........................................................................................................ 6-1
6.4 Layout of the boards ............................................................................................. 6-3
6.5 Detaching and Assembling Circuit Boards ........................................................... 6-4
6.6 Function of board .................................................................................................. 6-4
6.6.1 Control Framework .................................................................................. 6-4
6.6.2 Main Board .............................................................................................. 6-5
6.6.3 Three-disk Driver Board........................................................................... 6-6
6.6.4 Three-probe Driver Board ........................................................................ 6-7
6.6.5 Pre-amp Board ........................................................................................ 6-8
6.6.6 AD Conversion Board .............................................................................. 6-8
6.6.7 Reagent Refrigeration Board ................................................................... 6-9
6.6.8 Level Detection Board ............................................................................. 6-9
6.6.9 Pump/Valve Driver Board ........................................................................ 6-9
6.6.10 Reaction Disk Temperature Control Board .......................................... 6-10
6.6.11 Preheat Temperature Control Board .................................................... 6-10
6.6.12 Reaction Disk Heater Connection Board ............................................. 6-10
6.6.13 Simulate power connection board ....................................................... 6-10
6.7 Power Supply Module ......................................................................................... 6-10
6.7.1 Features of Power Supply Module ........................................................ 6-11
6.7.2 Block Diagram ....................................................................................... 6-12
6.8 Connection Diagram ........................................................................................... 6-13
6.9 Board Indication Light ......................................................................................... 6-27
7 Service and Maintenance..................................................................... 7-1
7.1 Preparation ........................................................................................................... 7-1
7.1.1 Tools......................................................................................................... 7-2
7.1.2 Wash Solution .......................................................................................... 7-2
7.2 Daily Maintenance ................................................................................................ 7-2
7.2.1 Checking Connection of Deionized Water ............................................... 7-2
7.2.2 Checking Waste Tubing ........................................................................... 7-3
7.2.3 Checking Sample/Reagent Syringes ....................................................... 7-4
7.2.4 Checking/Cleaning Sample Probe ........................................................... 7-4
7.2.5 Checking/Cleaning Reagent Probe ......................................................... 7-4
7.2.6 Checking/Cleaning Sample/Reagent Mixers ........................................... 7-5
7.2.7 Checking Printer/Printing Paper .............................................................. 7-5
7.2.8 Checking Printer/Printing Paper .............................................................. 7-5
7.2.9 ISE Unit (optional).................................................................................... 7-5
7.3 Weekly Maintenance ............................................................................................ 7-6
7.3.1 Cleaning Sample Probe ........................................................................... 7-6
7.3.2 Cleaning Reagent Probe ......................................................................... 7-7
7.3.3 Cleaning Sample/Reagent Mixers ........................................................... 7-8
7.3.4 Cleaning Sample/Reagent Bar Code Reader Windows .......................... 7-9
7.3.5 Cleaning Sample Disk/Compartment .................................................... 7-10
7.3.6 Cleaning Reagent Disk/Compartment ................................................... 7-11
7.3.7 Cleaning Panels of Analyzing Unit ......................................................... 7-11
7.3.8 Cleaning Reaction Cuvettes .................................................................. 7-11
7.3.9 Checking Photometer ............................................................................ 7-12
7.4 Monthly Maintenance.......................................................................................... 7-16
7.4.1 Cleaning Wash Well of Sample Probe ................................................... 7-16
7.4.2 Cleaning Wash Well of Reagent Probe ................................................. 7-17
7.4.3 Cleaning Wash Well of Sample/Reagent Mixers ................................... 7-18
7.4.4 Cleaning Sample Probe Rotor ............................................................... 7-18
7.4.5 Cleaning Reagent Probe Rotor ............................................................. 7-19
Contents III
7.4.6 Cleaning Sample/Reagent Mixers Rotors ............................................. 7-19
7.4.7 Checking and Maintaining Wash Unit .................................................... 7-19
7.4.8 Replacing Reaction Cuvettes (Whole Disk)........................................... 7-21
7.5 Three-month Maintenance ................................................................................. 7-24
7.5.1 Washing Water Tank .............................................................................. 7-24
7.5.2 Washing Dust Screens .......................................................................... 7-24
7.6 Six-month Maintenance ...................................................................................... 7-25
7.6.1 Replacing Check Vavles ........................................................................ 7-25
7.6.2 Replacing First and Second Phase Washing Tubing on Wash Unit ...... 7-27
7.6.3 Replacing DI Water Filter ....................................................................... 7-27
7.6.4 Replacing Wash Solution Filter.............................................................. 7-29
7.7 As-Needed Maintenance .................................................................................... 7-30
7.7.1 Unclogging Sample Probe ..................................................................... 7-30
7.7.2 Unclogging Reagent Probe ................................................................... 7-33
7.7.3 Replacing Sample Probe ....................................................................... 7-36
7.7.4 Cleaning Wash Well of Sample Probe ................................................... 7-37
7.7.5 Replacing Reagent Probe...................................................................... 7-38
7.7.6 Replacing Sample/Reagent Mixers ....................................................... 7-38
7.7.7 Replacing Syringe Plunger Assembly.................................................... 7-40
7.7.8 Removing Air Bubbles ........................................................................... 7-44
7.7.9 Replacing Lamp ..................................................................................... 7-44
7.7.10 Replacing Reaction Cuvette (Individual) ............................................. 7-47
7.7.11 Cleaning Liquid Pump .......................................................................... 7-49
7.7.12 Replacing Waste Tubing ...................................................................... 7-53
7.8 Maintaining ISE Module (Optional) ..................................................................... 7-53
7.8.1 Replacing Reagent Pack ....................................................................... 7-53
7.8.2 Replacing Electrodes ............................................................................. 7-53
7.8.3 Replacing Tubing ................................................................................... 7-54
7.8.4 ISE Unit Storage (optional) .................................................................... 7-54
7.9 Quick-wear Parts ................................................................................................ 7-56
8 Test and Maintenance Software .......................................................... 8-1
8.1 Basic Operations .................................................................................................. 8-1
8.1.1 System Installation ................................................................................... 8-1
8.1.2 Overview .................................................................................................. 8-4
8.1.3 Operating Commands.............................................................................. 8-5
8.2 Macro Instructions .............................................................................................. 8-13
8.2.1 Function ................................................................................................. 8-13
8.2.2 Detailed Operations ............................................................................... 8-13
8.3 Parameter ........................................................................................................... 8-15
8.3.1 Detailed Operations ............................................................................... 8-16
8.4 Application Cases ............................................................................................... 8-17
8.4.1 Running.................................................................................................. 8-17
8.4.2 Checking ................................................................................................ 8-17
8.4.3 Debugging ............................................................................................. 8-17
9 Troubleshooting ................................................................................... 9-1
9.1 Classification of Error Messages .......................................................................... 9-2
9.2 Corrective Actions ................................................................................................. 9-4
9.2.1 Failures of Operation Unit ........................................................................ 9-4
9.2.2 Failures of Analyzing Unit ...................................................................... 9-14
10 Calculation Methods .......................................................................... 10-1
IV Contents
10.1 Reaction Types ............................................................................................... 10-1
10.1.1 Endpoint ............................................................................................... 10-1
10.1.2 Fixed-time ............................................................................................ 10-4
10.1.3 Kinetic .................................................................................................. 10-6
10.2 Prozone Check .............................................................................................. 10-10
10.2.1 Reaction Rate Method ....................................................................... 10-11
Contents V
For Your Notes
VI Contents
1 System Description
1.1 Overview
The BS-380/BS-390 is a fully-automated and computer-controlled chemistry analyzer
designed for in vitro quantitative determination of clinical chemistries in serum,
plasma, urine and CSF (Cerebrospinal fluid) samples. The BS-380/BS-390
Chemistry Analyzer consists of the analyzing unit (analyzer) and operation unit.
1.3 Functions
The general working procedure of the BS-380/BS-390 is as follows:
3. The reagent disk rotates to R1 aspirate position, and reagent probe aspirates R1
from a bottle on the reagent disk.
4. When washed for 8 phases, the reaction cuvettes are carried to the reagent
dispense position, and the reagent probe rotates to the reaction disk and
dispenses R1 to a cuvette.
6. The sample disk rotates to the sample aspirate position, and the sample probe
aspirates designated amount of sample from specified sample tube.
7. The reaction cuvette with R1 dispensed rotates to the sample dispense position,
and the sample probe dispenses the sample in the reaction cuvette.
8. With sample dispensed, the reaction cuvette rotates to mixing position for stirring.
10. The reaction disk with sample dispensed rotates to the reagent dispensing
position, and the reagent probe dispenses R2 to a reaction cuvette.
11. With R2 dispensed, the reaction cuvette is carried to the mixing position for
stirring.
12. During each period, the reaction cuvette receives photometric measurement
(absorbance reading taking).
13. The reaction cuvettes in which reaction is finished are washed when passing by
the wash unit.
2.1.1 General
System
System structure
Sample type
Throughput
300 tests/hour, or
Analytical method
Reaction time
Reaction temperature
370.1
Test scope
Predilution
Operation mode
System and tests are configured via the operating software. Profiles and calculation
tests are allowed.
Calibration rule
Linear (one-point, two-point and multi-point), Logit-Log 4p, Logit-Log 5p, Spline,
Exponential, Polynomial and Parabola
Data processing
Capable of storing and outputting various data and tables/graphs, and calculating
among different tests
Dimensions
Weight
200 kg
Emergent samples
Network connection
Blood collecting tube: 1268.5 mm, 1299 mm, 12.775 mm, 12.7100 mm,
13 X 75 mm, 13 X 95 mm, 13 X 100 mm;
Plastic tube: 1268.5 mm, 1299 mm, 12.775 mm, 12.7100 mm, 13 X 75
mm, 13 X 95 mm, 13 X 100 mm.
Sample disk
75 positions, which include the positions for calibrators, contros, STAT samples,
deionized water and wash solution
STAT sample
Emergent samples can be inserted during measurement at any time and then run with
high priority.
Sample volume
Sample probe
One probe, which is capable of detecting liquid level and obstruction (in horizontal and
vertical directions), and of tracking liquid level
Inside and outside of the probe are washed with carryover less than 0.1%.
The reagent bar code is in conformity with the NCCLS standard and also compatible
with various application environments. The total length of reagent bar code is within
15-30 digits.
Name Description
Symbology Codabar, I 2 of 5 (interleaved 2 of 5), code128, code39,
UPC/EAN and Code93
Maximum bar 0.19mm
code density
Total length 13-30 digits
Bar code User-defined
format and
contents
Max. width of 55mm
bar code level
Min. height of 10mm
bar code label
Max. 5 degree
inclination
angle
Print quality Class A (ANSI MH10.8M)
Wide and 2.5:1 to 3.0:1
narrow ratio
Reagent refrigeration
Reagent dispensing
Reagent types
Reagent volume
Reagent disk
Ordinary reagent disk, including inner and outer circles, 60 positions in total
60 reagent bottles can be held on the reagent disk. Each reagent position can hold
Mindray outer-circle 20ml/40ml and Mindray inner-circle 40ml bottles.
Reagent probe
One separate probe, which is capable of detecting liquid level and obstructions (in
horizontal and vertical directions), and tracking liquid level
Inside and outside of the probe are washed with carryover less than 0.1%.
5mm
72
Stirring method
Two mixers sharing one rotor, which stir when sample and/or R2 is dispensed
respectively
150-360l
Photometric system
Static fiber transmission, and reversed optics of holographic concave flat-field gratings,
Photodiode measuring each wavelength
Wavelength
12 wavelengths, which are 340nm, 380nm, 412nm, 450nm, 505nm, 546nm, 570nm,
605nm, 660nm, 700nm, 740nm and 800nm
Light source
Gratings type
Wavelength accuracy
2nm
150l
Photodiode array
Measurement range
Operating system
Communication interface
RS-232
Printer
Input device
Output device
Storage device
Power
< 1000VA
Water consumption
< 10L/hour
Operating environment
2.2.2 Timing
e. Aspirating sample
i. Dispensing sample
Go to next period
c. Dispensing R2
k. Aspirating R1
o. Dispensing R1
w. Aspirating R2
Go to next period
c. Washing mixer
Go to next period
The bearing platform (or ground) should be level with gradient less than 1/200.
The bearing platform (or ground) should be able to bear 350Kg weight.
The installation site should be free of corrosive gas and flammable gas.
The installation site should not be disturbed by great noise or power supply.
The system should not be placed near brush-type motors and electrical contacts
that are frequently powered on and off.
Do not use such devices as mobile phones or radio transmitters near the system.
Electromagnetic waves generated by those devices may interfere with operation
of the system.
To check grounding:
2. As shown in following figure, insert black and red pins into holes A and B separately.
The reading shall be the nominal voltage value (for example, 220V for mainland
China).
The distance between the power socket and the system should be less than 2.5
meters.
WARNING:
2. Check water supply pressure and flow: before start up for the first time, turn on
water treatment system first. And then turn on main unit power and analyzing unit
power. If water supply connection is correct, it can be seen that water tank is being
filled with water when open front door of analyzing unit. Record how long it takes to
fulfill the water tank.
Using graduate instead of 15L tank to immit 450 ml water, and time to fulfill the
tank is t (unit: seconds), it is considered that water flow meets requirement when t is
less than 100 seconds. Otherwise, check if tubing is too long or bent.
The tubing between fluidic inlet and diluted wash solution bucket should be no
longer than 2m.
The tubing between fluidic outlet and waste sewer should be no longer than 5m.
The waste sewer must be higher than the ground within 100mm.
1. Put high concentration waste tube and high concentration waste sensor into high
concentration waste bucket.
2. Stretch 2 low concentration waste tubes (thick and thin) into waste drainage sewer.
Note: Tube shall not be too long. Cut off the extra tube when tube is placed properly.
Make sure tube is not bent or clogged.
3. Low concentration tube1 (thick one) being placed improperly would probably lead
to Low concentration waste overflow failure occurring frequently during running of
test. While arranging tubing, the tube shall not exceed 5m; waste sewer shall higher
than the ground within 100mm; if waste sewer is higher than ground, adjust tubing
as shown in following figure, so as to ensure tube drops naturally.
4. After finishing installation testing as specified in 3.3, run waste draining checking in
maintenance screen of the operating software. If warning Please check low
concentration waste tube1 is not prompted, waste drainage is normal.
5. After ensuring waste drainage is normal, fix low concentration waste tube to avoid
it being moved easily.
CAUTION:
The water must meet requirements of the CAP Type II water; otherwise
insufficiently purified water may result in misleading measurement.
NOTE:
When inserting tubes into connectors of high-concentration waste outlet
and wash solution inlet on the rear side of analyzer, please make sure it
is inserted properly and firmly. A clear sound during connection indicates
a proper connection. Otherwise, please insert again to prevent poor
connection.
High-concentration waste tube overflow may lead to wash unit overflow.
Poor connection of wash solution tube may lead to no water supplied to
phase 1 and phase 2 wash.
Note: DI water filter is installed between water supply module and water source, so as
to protect the water supply module and the analyzer.
NOTE:
When water supply module is configured, find the water inlet weight
block (as shown in following figure) from the accessories pack to
connect onto the inlet end of water inlet tube, so as to ensure the inlet
end sinks to the bottom of water.
Wall paper scissors or other bit tool that can cut tubing.
3.3.2 Unpacking
Before unpacking, please check against packing list and see if packaging is
complete. There are another 4 cases besides PC and printer, which are analyzer
main unit, accessories pack, high concentration waste bucket, and wash solution
bucket.
The gross weight of the analyzer is about 300Kg. It is recommended to use fork lift
to unload the instrument.
Use adjustable wrench to loosen the screws to remove the top cover and side
Use adjustable wrench to remove the 4 fixing brackets and all screws on the fixing
angle steel. Remove the angle steel.
Use wide caliber adjustable wrench to remove the fixing nuts on feet bolts (4 in total).
A slop ramp is fixed to the right side plate. Remove the retaining screws (2 in total) to
remove the ramp.
Place the slop ramp on the side with hole on bottom plate. Fix the ramp with screws
removed from the packaging box.
Note: Store all packaging plates and retaining screws properly. Remain for later use.
Remove the package and plastics (probes arms, syringes and wash unit).
1. Take out sample and reagent probes from accessories pack. Pay attention to the
white gaskets in the package. Place the gasket inside the metal connector of the
probe. (Note: reagent probe gasket is larger than sample probe gasket.)
2. Remove probe arm cover: pull out the cover from bottom and lift up.
4. Install sample and reagent probes onto the arm. (Note: Make sure probe can
move vertically after installation.)
7. After installation, ensure probe base block has blocked the collision detection
8. Fill the clean open container with DI water. Put the tip of the reagent probe 2-3
mm under the water level. The indicator D5 on the level sensing board will go
through a process of OFF-ON procedure. After the tip of the reagent probe is
taken way from the water, the indicator D5 will go off, which shows the function
of the board is normal. Proceed to the next step.
Install mixer.
1. Take out mixer from accessories pack. Pull the mixer arm to the vertically highest
point.
3. Sleeve the mixer installation hole on mixer motor rotor. There shall be no
clearance between installation hole and motor rotor in vertical direction inside
the hole.
4. Tighten the retaining nut clockwise. Check if mixer is perpendicular. If not, please
install again.
Note: Diluted wash solution filter is included in accessories pack. It shall be placed
into external diluted wash solution bucket after installation personnel have
connected it into diluted wash solution tubing inlet.
Connect analyzer main unit, PC, printer, water treatment system (or water supply
module). Note: Do not switch on.
2. Open the electrode from its protective packaging and remove the yellow insert
from the lumen of the reference electrode. Place the reference electrode inside
3. Install other electrodes one by one into ISE module. Cl, K, and Na electrodes can be
easily inserted, while it is necessary to gently push the compression plate when
installing the spacer on top.
4. Check if all 5 electrodes have been installed correctly. Make sure they are aligned
vertically, with frontal sides of each electrode aligned.
6. Open the door in the middle. Take out the reagent pack adapter, remove the red cap
CAUTION:
After installing ISE electrodes, the ISE module shall be powered on all
the time. If power is off for more than half an hour, electrodes shall be
removed and stored properly. Refer to Operators Manual for details.
7. Remove the ISE plastic stopper in sample probe movement track on the right side
of the panel.
Turn on PC. The operating software will run automatically. Log in as service
personnel. (The user name and password is restricted to service personnel. User
shall not be accessed to it. Advanced user name: bsmindray. Password:
MINDRAY#BS ) Note: Select Quick Mode (to skip startup initialization.).
Choose Emergency Exit when log off (to skip shutdown procedure).
Disable operating system standby and screen saver: Enter Screen Saver page on
Display Properties screen, and select None for screen saver setup. The select
Power button to enter Power Options Properties page for following setup:
CAUTION:
Any failure during the process of initialization will lead to system failure
status. Tests cannot be run until failures are troubleshooted. And then
execute initialization again.
There may be fresh water spilling onto the surface around the wash well
during Prime Water Tank/Probes/Mixers, wipe the water off with dry
and clean cloth.
When priming for the first start-up, Prime Wash Unit may not be executed
completely. And it needs to be run again in following steps.
Select Setup from the main screen, and disable the two options of Temperature
be Steady and Light Source be Steady. After saving the changes, ensure the
system is in Idle status. Execute Prime Wash Tubing immediately, or the system
will be in Incubating status. That is to say, it will be in Idle status after another 20
to 30 minutes when reaction disk temperature and light source are steady.
Select an operation item and select Execute on the Daily Maint. page. The
Confirm dialog box pops up. Select the Prime Wash Unit option and the system
Enter Setup screen, and enable the two options of Temperature be Steady and
Light Source be Steady. Save the settings.
Execute Cuvette/ Lamp Check, and select Cuvette Check button. Select Start.
The checking will be complete after 20 minutes. Check if there are any cuvettes
highlighted in red. If yes, replace corresponding cuvettes.
The checking will be complete after 3 minutes. View and record results in installation
checking list.
Request "water" test in Sample Request page and duplicates for 72.
Load deionized water in assigned position of reagent disk as reagent for the test,
deinoized water and wash solution in position W and wash solution position
respectively for enhanced wash after test.
Load deionized water in assigned position of sample disk as sample for the test,
deinoized water and wash solution in position W and wash solution position
respectively for enhanced wash after test.
Review test results after testing is over. If more than 90% of the results are within
-1.5 to 1.5, go to next step. If not, check cuvettes with over ranged results.
Troubleshoot and rerun. (Note: Check cuvettes with over ranged results. If there
are cases such as optical surface dirty, scatch, or broken, clean or replace
cuvettes.)
Service personnel can choose Emergency Exit. Note: analyzer will not run
shutdown procedure under emergency exit. User can choose normal Exit. The
analyzer will run complete shutdown procedure, including turning off reaction disk
and DI water temperature control, and turning off lamp.
Turn off analyzing unit power after exiting the operating software.
4.1 Enclosure
4.1.1 Components
The enclosure protects the inner parts of the analyzer from damage and dust,
consisting of protection shield, panel, left/right side plate, middle door cover and rear
plate. See Figure 4-1.
CAUTION:
When removing and installing the enclosure, place the Main Power
and Power to OFF.
Generally, it is not necessary to remove the protection shield and middle door cover,
since they do not hinder the removal and installation of other parts. Remove one end
of the spring, then the gemel assembly and retaining screws of shield support, to
remove the protection shield if necessart. Remove the door gemel to remove the
middle door cover.
When removing the panel, remove the rear upper plate first. Remove the retaining
screws on rear upper plate to remove it.
CAUTION:
4.2.1 Introduction
The sample/reagent probe unit consists of the sample probe and reagent probe
assemblies, which are often called Two-probe Assembly.
The sample probe assembly includes sample probe, which aspirates sample from the
sample tube and then dispenses it into reaction cuvette. The reagent probe assembly
includes a reagent probe, which aspirates reagent and then dispenses it into reaction
cuvettes.
Generally, both of the two probes are capable of detecting liquid level and obstructions
in the horizontal and vertical directions.
The drive part supports the probe arm and drives the arm to move vertically or
horizontally, so that the sample probe and reagent probe move among different
positions.
The drive part includes the horizontal movement structure and vertical movement
structure. Both structures have stepper motors, timing belt wheel and timing belt.
Integrated with a bracket, the two structures finally drive vertically or horizontally the
probe arm via the spline shaft.
The probe arms are composed of the sample/reagent probes, liquid level detection
board, arm cover, etc, which are integrated by the arm base.
Besides the structural difference, the two probe assemblies differ from each other in
the horizonral rotation limit ring and liquid level detection board. See Figure 4-7.
4.2.3 Installation
Figure 4-8 Installation of two probe assemblies
3. Sample/Reagent probe unit is mounted on the big board with 3 M5X20 socket head
screws with spring washers. Remove the 3 screws to take out probe unit.
Note:
2. Keep sample/reagent probe assembly surface clean during installation and removal
process.
4.3.1 Introduction
The mixer assembly includes the sample mixer and reagent mixer sharing one rotor,
used to stir the reagent and sample in reaction cuvette.
Additionally, the mixers are also able to limit their mechanical motions or lock
themselves when power failure occurs.
Working positions of the mixer assembly: sample mixer wash well (reagent mixer wash
well) reaction disk.
The drive part supports the mixer arm and drives the arm to move vertically or
horizontally, so that the mixers move among different positions.
The drive part supports the mixer arms and drives the arm to move vertically or
horizontally, so that the mixers move among different positions.
The drive part includes the horizontal movement structure and vertical movement
structure. Both structures have stepper motors, timing belt wheel and timing belt.
Integrated with a bracket, the two structures finally drive vertically or horizontally the
mixer arm via the spline shaft.
The mixer arm consists of a mixer, motor, motor gasket, enclosure, etc, which are
integrated by the arm base.
2. Mixer motor is mounted on mixer arm base with 2 M2X4 cross pan head
screws with plain washers. Open arm cover, and remove the 2 screws to take
out the motor.
Note:
1. When installing mixer, bind the end plane of mixer with motors protruding
surface, and tighten the locking nut.
2. Keep the mixer surface clean during installation and removal process.
4. Do not remove the screws indicated by the red circle in the figure above.
a. Holding sample tubes: Sample containers (tube, microtube, etc) with samples
are placed on the sample disk, and then the sampling structure aspirates
sample and dispenses them into reaction cuvette.
b. Timely feeding: The sample disk must carry specified sample tube to the
aspirate position for aspiration according to the predefined timing. The sample
disk is driven by the drive part.
c. Sample identification: The sample disk must be able to identify the samples
automatically. This function is achieved by the bar code reader system.
Sample disk: The sample disk holds the samples and in conjunction with the drive part
carries them to the aspirate position.
Drive part: The drive part drives the sample disk to carry samples timely to the aspirate
position.
Bar code reader: The bar code reader identifies the samples correctly by scanning the
bar code label on sample tubes.
4.4.3 Servicing
a. Set the sample disk components on the drive part from top to down, ensuring
the pins on the drive part are aligned correctly to the holes on upper sample
disk.
2. Use three M38 socket head screws with spring washer to fix the sensor to the
base plate.
3. The distance between the bottom surface of small belt wheel and motor is 1.9mm,
which is guaranteed by fixture BA40-J27.
4. Use four M412 socket head screws with plain/spring washers to fix the motor
assembly to the base plate. Use fixture BA30-K24 to adjust the tension of timing
belt within 0.19kgf-0.22kgf.
a. Place two sponge cushions to two sides of the glass window. Please note not to
contaminate the glass window. Stick a sponge adjusting spacer to the dust shield and
ensure the spacer is aligned to the corresponding hole on the dust shield.
b. Place the prepared glass window in the groove of the sample compartment and
secure it with the dust shield, then tighten them with four M38 cross pan head
screws.
c. Use two M38 cross pan head screws to fix the conductive brush to the sample
compartment. Connect the conductive brush cable to the base plate.
d. Use two M48 socket head screws with plain/spring washers to fix the sample
compartment to the upper-front beam. Use fixture BA40-J11 to align the sample
compartment to the drive shaft and prevent the sponge spacer from shielding the light
entrance of the bar code reader.
e. Install the sample bar code assembly. Use three M516 socket head screws with
plain/sponge washers to fix the sample bar code assembly to the base plate. Connect
the bar code reader cable and fix it to its bracket.
g. Check the connection of all cables on the analyzer and then switch on the power
supply. The system resets mechanically. Turn on the laser beam in sample bar code
unit. Then the sample bar code reader emits light beams. Be sure not to stare into the
light beams. Otherwise your eyes may get hurt.
h. Adjust the sample bar code reader properly so that the light beam from it can pass
through the slit on the fixture. Use four M38 socket head screws to secure the bar
code reader to the two adjusted directions.
a. Remove the sample disk cover, and then remove the front panel.
b. Unplug the cable of the sample bar code reader and loosen the clip. Loosen the two
M38 socket head screws and then remove the sample bar code reader. Install a new
sample bar code reader to the bracket.
c. Adjust the sample bar code reader according to steps e, h, g and f in 1. Installing
Sample Bar Code Assembly (including sample compartment). Please note not to
shield the light entrance of bar code reader with the sponge spacer.
e. Install the front panel, and then cap the sample disk.
4.5.1 Introduction
1. Load reagents: Two circles with 60 positions in total are on reagent disk, of which 30
positions are available respectivelt on the inner and outer circles. The reagent
2. Refrigeration: The reagent disk unit is capable of refrigerating and keeping the
reagents at 2-8 in 24 hours a day, so that the reagents are always steady and will
not volatile.
3. The reagent disk rotates, driven by the drive module, carrying each reagent bottle to
the aspirate position.
The following figure shows the reagent disk unit on the analyzer.
The reagent disk assembly is used to hold reagent bottles and rotates, carrying each
reagent bottle to the aspirate position for reagent aspirating. The reagent disk
assembly includes the handle, retaining screws, reagent disk bracket, reagent bottles,
bottle holder and reagent disk base.
The reagent refrigeration assembly is used to provide refrigeration function and keep
the reagents in a low-temperature environment, so that the reagents are always
steady and will not volatile. The reagent refrigeration assembly is composed of
refrigeration compartment assembly, cooling air duct assembly.
A reagent bar code reader is provided to input reagent information automatically. The
reagent bar code assembly is composed of the bar code reader, bracket, the anti-fog
and heat device, etc.
1. Use four M520 socket head screws with spring washer to fix the reagent disk drive
part to the base plate of the analyzer.
2. Use three M38 socket head screws with spring washer to fix the sensor to the
base plate.
3. Use four M412 socket head screws with spring washer to fix the motor to the
base plate.
4. Use two M48 socket head screws with spring/plain washers, and eight M48
screws to fix the air vent to the base plate.
5. Use four M48 socket head screws with spring/plain washers to fix the reagent
refrigeration compartment assembly to the base plate.
6. Align the reagent disk assembly to rotation bearing house, and tighten the retaining
screws.
8. Use three M516 socket head screws with spring/plain washers to fix the bar code
bracket to the base plate. Use two M38 socket head screws with spring/plain
washers to fix the bar code reader support to the bracket. Use two M38 socket
head screws with spring/plain washers to fix the bar code reader to the support.
Note:
1. For intrument without bar code reader equipped, after steps 1 to 6, use four M312
cross pan head screws to fix the window cover to the lateral side of reagent
refrigeration compartment.
Precautions:
1. The tension of the sychronous belt should be adjusted while installing motor
assembly.
3. Adjust the light beam position when install bar code reader.
4. The direction of motor cables connection should face that of the air vent outlet.
The reagent disk assembly includes the handle, spring screws, reagent bottles, bottle
holder, reagent disk bracket and reagent disk base. See Figure 4-18.
Installation procedure:
2. Use two M412 cross pan head screws with stainless steel plain washer to fix
the two handles to the reagent disk bracket.
3. Use four M48 cross pan head screws to fix the reagent disk bracket to the
base.
Precautions:
3. The bottle holders should be installed under the base properly. Do not break the
retaining clip in the bottom of bottle holders.
Installation procedure:
1. Put the reagent refrigeration bottom up, and remove a nut and spring washer from
the temperature sensor connector; apply some epoxy resin in the circumference of the
sensor. Do not break the temperature sensor cable.
2. Place two insulation sponges inside the reagent compartment grooves. Watch the
distance between the sponge and the bushing boss.
3. Coat the worded side of the refrigerating plate with heat glue (0.1-0.2mm thick) and
then place it in the groove of the insulation plate with glue side downwards, guide the
cable through the cable groove, then stick a heat film to the no-word side of the
refrigerating plate.
4. Place the radiators in the corresponding grooves of the reagent compartment and
close to refrigeration plate. Place square coil spring into the hole of radiator, and lead
the retaining screws of the radiator through the spring. Tighten the retaining screws in
the bottom of refrigeration compartment. Finally, apply some epoxy resin around the
radiator.
6. Use eight M450 cross pan head screws to fix the fan and protector hood to the air
vent.
7. Stick the acoustic absorber to the inside of air vent outlet, and keep them flat.
8. Install the wiring protector ring into the wiring holw on the vent.
9. Use four M48 socket head screws with spring/plain washers to fix the refrigeration
assembly to the vent.
Precautions:
The reagent bar code assembly is composed of the bar code reader, bracket, the
anti-fog and heat device, etc.
Installation procedure:
1. Use two M38 socket head screws with plain washer to fix the small bracket of
reader to the large support.
2. Install the reader to the small bracket and secure it with two M38 socket head
screws with plain/spring washers.
Precautions:
1. Be sure not to contaminate the glass window of the reader. Otherwise the
scanning performance may be compromised.
2. The screws to secure the reader should not be tightened unless you have
adjusted the reader properly.
1. Place a silica gel cushion in the groove of the anti-fog device mounting plate.
3. Use six M28 cross pan head screws to fix the heat board to the mounting plate
with its grooved side upwards.
5. Coat little heat glue to the heater on the downward side of the
overheat-protection switch, and then use a M312 socket head screw to press
out the overheat-protection switch.
6. Use a M312 socket head screw to fix the dust shield to the mounting plate.
7. Stick a sponge spacer to the dust shield of the bar code reader.
Precautions:
1. The window on the rubber cushion should be level to that on the mounting plate.
4. The window on the sponge spacer should be level to that on the dust shield, so
that the light beams from the bar code reader can pass through successfully.
4.6.1 Introduction
The reaction disk assembly holds reaction cuvettes and rotates clockwise, carrying the
cuvettes to specified positions for sample/reagent dispensing and stirring, and wash
solution dispensing. Reagents and sample react with each other in reaction cuvette.
Also the reaction disk assembly provides a constant-temperature environment for the
reaction.
The reaction disk unit consists of the reaction disk assembly, drive part, reaction
compartment assembly, coder sensor assembly and motor assembly. See Figure
4-22.
Drive part: Used to drive the reaction disk assembly to rotate and carry reaction
cuvettes to specified positions for sample/reagent dispensing and stirring, and wash
solution dispensing. During operation, the motor drives the axis to rotate via the timing
belt.
Motor assembly: Used to provide force which drives the reaction disk assembly to
rotate via the belt and two belt wheels.
Coder sensor assembly: Used to find the mechanical zero position and count the valid
edges of the coder.
2) Thread four M520 screws with spring washer through the bottom of the base
plate to fix the drive part on it. See Figure 4-26.
2. Install the motor with damping cushion on the mounting plate and install the small
belt wheel on the motor axis. See Figure 4-28.
3. Use four M412 socket head screws with plain/spring washers to fix the mounting
plate to the stand bars. Please note not to tighten the screws right now and not
reverse the connector of the motor. See Figure 4-29.
5. Install the belt on the big and small belt wheels, adjust the tension of the belt using the fixture,
and then tighten the four M412 socket head screws.
2) Use three M420 cross pan head screws with plain washer to secure the reaction
compartment to the stand bars, and then tighten the three screws.
Precautions:
Before installing the reaction compartment, make sure you have installed the reaction
disk drive part, motor assembly and optical measurement assembly.
2. Use four M516 socket head washer screws to fix the reaction disk assembly to
the rotor sleeve. See Figure 4-33.
3. Install the skylight cover to the drive plate with two spring screws, and make sure
the notch on the skylight cover aligns to its counterpart on the reaction disk.
4. To replace the heater, remove the lower clamp, the presser plate and the wire
pressing ring.
5. To replace the temperature sensor, remove the lower clamp, the upper clamp, the
wire pressing plate and the wire pressing ring.
6. To replace the protection switch, remove the wire pressing plate and the wire
pressing ring.
Precautions:
Do not remove the screws connecting the reaction disk to the drive disk and those
connecting the drive disk to the locating ring.
4.7.1 Introduction
Chemistry analyzer is a typical precision instrument which features in optics,
mechanics, electronics and logarithm. The spectrophotometer is one of the key
components of the instrument and determines directly the precision and accuracy of
measurement by the system.
Open the shielding box of AD collection board (See Chapter 6), connect two probes of
the oscillograph to the AD start signal(RC and GND) and analog signal of channel
1(VG1-VG12), then connect the earth terminal to the ground. (Only the earth terminal
of one probe should be connected to the ground.)The channels, wavelength and test
points are listed in the following table.
Chan 1 2 3 4 5 6 7 8 9 10 11 12
nel
Wave 340 380 412 450 505 546 570 605 660 700 740 800
lengt
h
Test VG1 VG2 VG3 VG4 VG5 VG6 VG7 VG8 VG9 VG10 VG11 VG12
Point
The peak value of a normal signal is 5V. Both channel 1 and 2 should be adjusted to
2V, so that the photoelectric wave can be observed easily. Ensure the coupling mode
of the two channels is DC. Set up proper sampling interval to get waves easily. Set the
sampling mode to AUTO. See the figure below:
Sampling interval
100KS/s
4 Units and Modules 4-33
4.7.3.2 Adjusting Lamp Brightness and Photoelectric Collecting
Position
1. Enter the Reaction Disk Unit screen of the BS-380/BS-390 test and maintenance
software, select Reset Reaction Disk, and then turn on the lamp. See the figure below.
2. Use the multimeter to test the power supply adapter and check if the voltage at J16
is within 12.1-12.2V (lamp brightness is approximately within 235-239). If not, select
the Parameter tab and then select Reaction Disk Unit in the Unit field, adjust the lamp
brightness until satisfied. (The greater the parameter, the higher the voltage) After
adjusting the parameters, turn off the lamp and then turn it on so that you can get
adjusted voltage.
4. First test the waves at 340nm, set up the Circles to 1 and (cuvette) Position to 1, and
then select the Rotate and Measure button.
6. Find the waves for the five cuvettes in which water is dispensed. (In order to find the
waves easily, water should be dispensed to cuvettes No.24-28). Generally, the five
waves of the cuvettes with water are higher and flatter than those of other cuvettes.
If the waves are flat, the upper waves refer to AD start signals (In a bundle of collected
signals, the rightmost means 340nm and the leftmost means 800nm), and the waves
underneath refer to the photoelectric analog signals.
Check if the AD start signal at 340nm is in the middle of the photoelectric analog signal
(See the figure below). If yes, the photoelectric collecting position is correct.
If the AD start signal at 340nm is in the decreasing part of the photoelectric analog
signal instead of its middle (See the figure below), the photoelectric collecting position
is not correct and must be adjusted by moving the coder sensor of the reaction disk left
or right.
After the 340nm channel is adjusted, connect the probe 2 to VG12 of channel 12,
check the waves and collecting position of 800nm in the same way as 340nm. Make
sure that all AD start signals are in the flat part of the photoelectric analog signals.
Check if the waves of all channels are flat according to the step mentioned above. If
not, the pre-amplification board may go wrong and the optical assembly should be
replaced.
1. The lower limit of the light intensity alarm is calculated by the gain parameter of
340nm. The lower limit value is increased based on the gain increasement, which
causing the Weak light alarm cannot be released effectively by adjusting the gain.
(The calculated threshold value can be queried through Maintenance System
Maintenance Light Source Setup.)
2. The signal gain of the photoelectric unit has been configured properly before the
analyzer leaves the factory. When an alarm occurs indicating weak light, replace the
lamp instead of adjusting the signal gain. After replacing the lamp, check the new lamp
by executing Cuvette/Lamp Check on the Daily Maint. page of the operating
software.
NOTE:
Before testing the photoelectric gain, make sure that the lamp has been
on for at least 5 minutes; otherwise the lamp is not steady.
Select the Photoelectric Unit tab of the Test and Maintenance Software. Check if the
AD values for water blank of cuvettes No.24-28 are greater than 63000. See following
figure:
If the AD value exceeds the range, select the Parameter tab and then select Main Unit
in the Unit field, select Inquire to view the gain parameters of each channel (When the
gain parameter increases, the corresponding AD value will decrease), adjust the water
blank AD value of each channel within 47000-49000.
4. Remove the cover on the air duct of the light source assembly (Figure 4-38);
use a hex wrench to loosen the M3 retaining screw that fixes the fiber bundle on
the front plate of lamp housing; then unplug the fiber bundle (Figure 4-37).
5. Loosen the three screws that fix the heat chamber; raise the heat chamber with
one hand and lift up the optical assembly with the other hand so that the front
lens assembly is disconnected from the heat chamber.
6. Install the new optical assembly following the above steps reversely.
Precautions:
2. The fiber bundle is bound loosely by a clip on the support of the heat chamber.
Hold the fiber bundle carefully so that it will not touch the axis of the reaction disk.
When removing the fiber bundle, remove it from the clip; then thread the fiber bundle
back into the clip during installation.
3. After removing the old optical assembly, place it in the installation package together
with the fiber bundle, and then bring the package back or send it to our company for
servicing.
Wash assembly consists of wash probe assembly and drive assembly. Wash probe
assembly is connected to drive assembly via knurled screws. See Figure 4-49.
Precautions:
While maintaining, remove the protection shield first. Then remove the four screws,
and the syringe assembly. Replace problem parts.
Pump The pump module includes three peristaltic pumps, which are used
module to transfer reagents and waste liquid.
As shown in Figure 4-52, ISE module installation and remove are as follows:
Remove:
1. Remove the panel above ISE module and the right side plate of the main unit.
4. Remove the four M3X8 cross pan head screws, and remove the ISE module.
Install:
1. Install the ISE module to the shield with four M3X8 cross pan head screws.
3. Lead the drainage tubing through the hole on shield, and connect wiring (Note:
The tubing and wiring are not indicated in the figure).
Remove:
1. Open the panel above ISE module and the right side plate of the main unit.
2. Remove the fluidic tubing of pump module and motor cable (Note: Tubing and
cable are not indicated in the figure).
3. Three peristaltic pumps are installed to pump support with four M2.5X6 cross pan
head screws with 2.5 plain washer. Remove the pumps as needed.
4. The pump support is fixed on the base with four M4X10 socket head screws.
Remove it if necessary.
Install:
1. Use four M4X10 socket head screws to install the pump support to the base.
2. Use four M2.5X6 cross pan head screws with 2.5 plain washer to install the
peristaltic pump to the support.
Remove:
Install:
3. Push the reagent pack horizontally into ISE reagent compartment. Do not bend
the tubing.
1. Open the reference electrode from its protective packaging and remove the yellow
insert. Place the reference electrode inside the housing by pressing down the
compression plate and push it straight against the back of the housing. (Note: Do
not throw away the yellow inset. It should be installed back when storing the
reference electrode.) Soak the electrode in warm water until the lumen of the
electrode has been cleared free of salt build-up if necessary.
3 Check if 5 electrodes have been installed properly. Ensure that the electrodes are
level with each other vertically as well as in the front.
Steps to remove the electrodes are the opposite to that of installation. Purge the
fluidics before removing the electrodes. If the electrodes are not use for a long time
after removal, store them properly. Refer 7.8.4 ISE Unit Storage (Optional) to for
more information.
CAUTION:
5.1 Introduction
1. The fluidic system of BS-380/BS-390 includes the sampling system and washing
system.
2. The sampling system is equipped with two probes, two mixers and two syringes. The
sample syringe is 100l and the reagent syringe is 500l.
3. The inside and outside of the two probes and two mixers are washed via liquid pump.
There are four wash wells collecting waste from washing the inside and outside of
the probes and mixers.
4. The reaction cuvettes are washed in 8 phases: 1) Phase 1-2: Cuvette is washed with
wash solution; 2) Phase 3-6: Cuvette is washed with deionized water; 3) Phase 7-8:
No liquid is added.
5. The wash solution and deionized water for cuvette wash are added via syringe. The
deionized water and diluted wash solution is preheated to 30~37.
6. The waste from washing is drained via liquid pump: 1) Phase 1-3: high concentration
waste; 2) Phase 4-8: low concentration waster; 3) Phase 7-8: the wipe blocks can
fully absorb the residual liquid in cuvette.
7. Water is supplied by water treatment system, with water pressure and flow specified.
8. The waste is collected by hollow plastic waste conflux tubing, whose installation
height is restricted: it is required that the waste can be drained by gravity. There are
floaters installed in the conflux tubing, so that system can give warnings to prevent
waste overflow when the waste tubing is clogged.
9. There are level sensor connector and external high concentration waste bucket
equipped for high concentration waste.
The cuvette washing system consists of dispensing module and drainage module.
The dispensing module is driven by syringe to dispense wash solution into cuvettes;
the drainage module is driven by liquid pump to draw waste from cuvettes. The
washing system relies on the repeated actions of dispensing and draining to realize
the repeated using of cuvettes.
In the mean time, the fluidic system of BS-380/BS-390 includes 5 external interfaces:
3 outlets respectively for draining high/low concentration wash waste and gravity
waste from wash wells, and 2 inlets respectively for providing diluted wash solution
and deionized water.
1. Sampling system
Sample Reagent
syringe syringe
2.2
Dispensing 2.1 Aspiration
module module
Preheat block
Sample Reagent
Reaction probe probe
Phase 1, 2 Phase 1 Phase 2/ Phase 4/ Phase 6/ Phase 8
Phase 36
wash waste 3 waste 5 waste 7 waste waste disk reagent
DI water
solution pump pump pump pump pump compartment Sample Reagent
waste mixer mixer
filter
Inlet valve
Water tank
Table 5-1 Corresponding relationship between wiring board and wash unit
Wiring board
No. Wash unit Indication
No.
1 13 Phase1 dispense probe D1
2 14 Phase2 dispense probe D2
3 15 Phase3 dispense probe D3
4 16 Phase4 dispense probe D4
5 1 Phase5 dispense probe D5
6 2 Phase6 dispense probe D6
7 3 Phase7 dispense probe D7
8 4 Phase8 dispense probe D8
9 12 Phase1 drain probe W1
10 11 Phase2 drain probe W2
11 10 Phase3 drain probe W3
12 9 Phase4 drain probe W4
13 8 Phase5 drain probe W5
14 7 Phase6 drain probe W6
15 6 Phase7 drain probe W7
16 5 Phase8 drain probe W8
1# M6G-020026---
2# M6G-020030---
3# M90-000025---
4# 3001-10-07069
5# M6G-020028---
6# 0040-10-32301
7# M6G-020049---
9# M6G-020022---
6.1 Overview
This chapter describes the function of circuit boards in the BS-380/BS-390.
If you need to detach the circuit boards, you must first switch off the Main Power of
the analyzer. Please wear gloves to protect the circuit boards from ESD (electrostatic
discharge) or release the charge first before detaching the circuit boards.
6 Hardware 6-1
receive photoelectric data.
The main board provides a BDM
(Background Debug Model) interface for
debugging software, and a serial port to
update its application software.
Power board This unit provides the power for the whole #4
12V board: machine.
051-000509-00
(050-000386-01)
24V board:
051-000510-00
(050-000387-01
Connection board:
051-000511-00
(050-000388-01)
Three-probe driver This unit can control and drive the reagent #5
board probe, the sample probe, the mixers, wash
unit and related parts to move.
BA38-30-87928
(BA38-20-87927A)
AD conversion board This unit can modify the analog signals from #6
the pre-amplification board and convert the
BA40-30-61365
analog signals into digital signals. Also this
(BA40-20-61364A) board provides a SPI (Serial Port Interface)
for connecting to the main board.
Pre-amplification board This unit can converse the light signals into #7
electrical analog signals by the photoelectric
BA40-30-61363
diode.
(BA40-20-61362A)
Level detection board This unit can test the samples level and #8
detects obstructions occurring to the sample
051-000360-00
probe.
(050-000283-01)
400ul reagent probe This unit can test the reagents level and #13
level detection board detects obstructions occurring to the
reagent probe.
051-000361-00
(050-000283-01)
Wash solution preheat This unit can process and collect signals #9
temperature control from two DI water temperature sensors and
board one environment temperature sensor. It can
also realize the AD conversion of these
BA38-20-88228
signals. It provides a SPI (Serial Port
(BA38-20-88227A) Interface) for connecting to three DI water
heater power supply and three-disk driver
board.
Pump and valve driver This unit receives signal from the #10
board three-probe driver board and then makes
the pumps and valves act.
BA40-30-61373
6-2 6 Hardware
(BA40-20-61372A)
Reaction disk This board collects the temperature sensor #11
temperature control signals from the reaction disk and converts
board them into digital signals. This board
provides a SPI (Serial Port Interface) and a
BA38-20-87909
power supply interface for connecting to the
(BA38-20-87910A) three-disk driver board via a slip ring.
Reaction disk heater It connects to heater power supply, provides #12
connection board interface for heater temperature protection
switch, and connects heater and
BA38-30-87925
temperature switch.
(BA38-20-87926A)
Simulate power The main function of the simulate power #14
connection board connection board is to provide separate
simulate power to the photometer system
BA38-30-88342
and conenct the 5V power of the main
050-000570-00 board and the photometer.
6 Hardware 6-3
Figure 6-2 Layout of the circuit boards-2
11#
12#
9#
10#
The analyzing unit (main unit) consists of the following units: the temperature control
system, the reaction system (include ISE), the photoelectric test system, the sample
and reagent delivery system, the mixing system and the auto clean unit etc.
6-4 6 Hardware
Figure 6-3 shows the control framework of the BS-380/BS-390.
Communicating with the PC through the RS232 to send commands, reply data
and test results.
Controlling the data acquired process of optical system.
Controlling the moving units action and collecting the status signal.
Controlling the temperature adjustment system and collecting temperature status
signal.
6 Hardware 6-5
Figure 6-4 Function of the main control board
All CPU on this board receive the orders from the main board through the RS232,
and decode it to act.
The CPU on board output signals to control the moving parts related with the
three disks.
This unit can receive the signals from the moving parts sensors, and other status
signals.
This unit can control the heater of the reaction disk (solid heater directly), the
pre-warm wash water and it can test the temperature of this two parts and the
environment temperature too.
Figure 6-5 shows the function framework of the three-disk driver board.
6-6 6 Hardware
Figure 6-5 Three-disk-drive boar
This unit can receive the orders from the main board through the RS232 and
transmit the test data to the main board.
This unit can control and drive the moving parts of reagent probe, sample probe,
mixers, wash unit, pumps, valves, syringes, etc.
This unit can receive the position signals from the moving parts sensors, and the
signal for protecting probes from collision in horizontal orientation.
This unit can test the signal for protecting wash unit from collision in vertical
orientation.
This unit can test the liquid level according the signal from the level detection
board and receive the signals for protecting the probes from collision too.
Figure 6-6 shows the function framework of the three-probe driver board.
6 Hardware 6-7
Figure 6-6 Three-probe driver board
6-8 6 Hardware
6.6.7 Reagent Refrigeration Board
This board is independent compared with other circuit boards; the unit can control the
cooler chip on or off and then make the reagents cool; it can adjust the temperature in
the reagent carousel ; this unit can also drive the fan of the whole system and reflect
the fans signal to the three disks control-driver board; the detail is:
Figure 6-8 shows the function framework of the reagent refrigeration board.
The two level detection boards have the same construction and interface and
detect the reagent level and sample level individually with the high reliability,
especially the sample level detection.
The circuit boards generate the level detection signal which is sent to
three-probe driver board, when the probes touch the liquid level.
This unit can protect the probe from vertical collision; it generates signal which is
sent to three-probe driver board.
Figure 6-9 shows the function framework of the pump and valve driver board.
6 Hardware 6-9
Figure 6-9 Pump/valve driver board
The power system consists of 3 boards: 24V board, 12V board, and power
connection board.
The 24V board transforms the AC power to the A24V, B24V and 24VLAMP (the lamp
source).
The 12V board transforms the AC power to the other 12V (B12V and C12V) and 5V
as the system needs.
6-10 6 Hardware
The power connection board has the function of relaying the AC power, converting
analog 12V, controlling the C12V ,support of A12V light source voltage and output
of the other voltages.
The power supply module provides all power through the interfaces on the power
connection board, and the 24V board, the 12V board and the connection board use
the plug board to board to connect.
The whole power system is an integrity module. It is shielded and isolated by the
metal enclosure.
6.7.1.1 Input
Input AC voltage: 100V-240VAC (fluctuation of 10%)
Frequency: 50/60 Hz (fluctuation of 3Hz)
Input power: 1KVA
Max instantaneous current: <40A
6 Hardware 6-11
6.7.1.7 DC Output: D12V for AD Conversion, Temperature
Control
Output current: 0.3A
Output voltage: 11.4- 12.6V
6-12 6 Hardware
6.8 Connection Diagram
Figure 6-11 Connection diagram 1
1 2 3 4 5 6 7 8
RE APPR
ECN DESCRIPTION DRAW CHECHK
V DATE
D D
PC
C C
AD conversion
ISE module DDB PDB
board
Power
assembly
Preheat Reagent level Sample level
Pre-
Pre - amp Reagent/
Reagent /Sample
Slip ring temp control detection detection
board barcode module
board board board
B B
APPROVALS DATE
DESIGN MINDRAY
CHECK
A TITLE A
Main unit wiring connection
? ? : ? ? ? ? ? ? ? ? ? ? ( ? ? ? ? ) ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? CHECK
? ? ? ? ? ? ? ? , ? ? ? ? ? ? ? ? , ? ? ? ? ? ? ? ? ? ? ? ( ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ) ? ? ? ? ?
File : Bytes : ? ? ? ? CHECK
CONFIDENTIAL DISCLOSURE : This set of drawing ( s ) and all it 's intellectual property rights ( including copyright ) subsisting DWG NO
NO. REV 1 .0
herein are property of Shenzhen Mindray Bio - m edical Electronics Co .,Ltd . No use , copies or reproductions should be made
A. - BA 38-
38 - 30-
30 - 036
Date : Tim e :
of this drawing or any part ( s ) thereof for whatever purpose nor shall any information , data , calculations , or other contents
R&D
contained in this drawing be dissem inated without prior written permission of Shenzhen Mindray Bio - medical Electronics SHEET 1 OF 14 SIZE A3
Software & Rev : Microsoft office Visio 2003 Co ., Ltd . CHIEF ENG.
ENG . A3
1 2 3 4 5 6 7
6 Hardware 6-13
Figure 6-12 Connection diagram 2
1 2 3 4 5 6 7 8
Lamp connection
BA38
BA38-
38-20-
20-88187
1 A12VOUT
1
Lamp 2 GND J16
2
B B
A
MINDRAY A
TITLE:
TITLE: Power board connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-14 6 Hardware
Figure 6-13 Connection diagram 3
1 2 3 4 5 6 7 8
DDB
BA38-30-88045
1
4
3
2
5
6
J8
10
12
11
9
8
7
D D
1 B24VOUT
2 B24VOUT
3 B24VOUT
DDB power cable
4 5VOUT
8 GND2
9 GND2
DGND
DGND
7 GND2
GND2
D12V
-12V
BA40-21-61748
5
10
11
12
6
A24V is generated by 24V board and provided to
1 B24VOUT 1 PDB power cable
ISE module.
1
2
3
4
5
6
2 B24VOUT 2 B24VOUT BA40-21-61705
PDB
10
11
12
1 1
7
8
9
1 5VOUT
3 B24VOUT 3 6 1
2 2 6 1 6 GND2
BA38-30-87928 B24V is generated by 24V board, and provided to
3 4 GND2 4 3 J15 7 2
2 B24VOUT 7 2
7 GND2
4 4
5
5 GND2 5
5
8 3 3
8
B24VOUT
GND2
8 3
J3 DDB, PDB, pump/valve driver board.
6 GND2 6 J14 9 4 4 C12VOUT 9 4
6 6
7 24VFAN 7 24VFAN 9 D12V
24V power board 7 7 10 5 5 -12V 10 5 24VFAN is generated by 24V board, and provided
8 8 24VFAN- 8 8 10 DGND
BA40-30-61625 9 9
A24V J10 Connection between to reagent refrigeration board and fan.
9 A24V 9
10
10 A24V- 10
10 pump/valve driver board and
C
11 11 power board 24VLAMP, generated by 12V board, generates C
12 11 24VCRL1 11 12
1
BA38-20-88182
C12VOUT
A12V via DC/DC module in power connection
13 12 NC 12 13 Pump/Valve
14 13 NC 13 14 2 1 3
5
C12VOUT
C12VOUT 1 2 driver board
board, and it is provided to lamp.
15 15 7 C12VOUT
4 3 3 4
14 AC_N 14
9 B24VOUT BA38-30-88046 B12V is generated by 12V board, and provided to
15 AC_L 15
6 5 11 B24VOUT 5 6
J4 8 7 12 B24VOUT
7 8
J1 reagent refrigeration board.
2 GND2
10 9 4 GND2 9 10
Power connection board 6 GND2 C12V is output by B12V via power connection
12 11 11 12
1 B12Vout 1 BA40-30-61627 8
10
GND2
GND2 board, and provided to PDB, pump/valve driver
2 GND2 2
1 1
Reagent refrigeration board, and reagent refrigeration board.
2
3 GND2 3
2 board power cable 1
3 4 5VOUT 4
3 BA40-20-61586
4 5 5VOUT 5 4
1 24VFAN+ Red 3 1 D12V and -12V are converted on power connection board by
5 6 5VCRL 6 5 3 1 2 24VFAN- Black
4 2 J17 14V generated from 12V board, and provided to DDB
6 6 J9 3 C12VOUT Yellow
7
7 GND1 7
7
4 2
4 GND2
connected to temperature control board, main control board
Green
B 12V power board 8 8 24VLAMP 8
8 J11 P1 Reagent connected to pre-amp board and AD conversion board, PDB B
P1 B12V Red
BA40-30-61623 9 9 +14V 9 9
refrigeration board connected to clog detection board (N/A in BA38).
P1 B12V
10 10 -14V 10 10 P1 Red
A A
Power board connection
A-BA38-30-036 1.1
3 14
1 2 3 4 5 6 7
6 Hardware 6-15
Figure 6-14 Connection diagram 4
1 2 3 4 5 6 7 8
D Pre-
Pre-amp board D
BA40
BA40-
40-30-
30-61363
2 4 6 8 2 4 6 8
J2 J3
1 3 5 7 1 3 5 7 J1 1 2 3
SIG6 orange
BA40-20-61485
Pre-amp board to AD
orange
yellow
gr een
yellow
AGND white
SGND black
green
Pre-amp board to AD
black
2 AGND black
white
gray
blue
gr ay
bl ue
blue
r ed
red
red
AGND
SGND
3 VSS
1 VDD
SIG1
SIG2
SIG3
SIG4
SIG5
SIG1
SIG2
SIG3
SIG4
SIG5
SIG6
C C
1
2
3
4
5
6
7
2
3
4
5
6
7
8
8
1
2
2 4 6 8 2 4 6 8 J1 1 2 3
J2 J3
1 3 5 7 1 3 5 7
AD conversion board
BA40
BA40-
40-30-
30-61365
1 1 1 1 1 1 2 2 2 2 2 2
P1 4 5 6 7 8 9 0 1 2 3 4 5
1 1 1 1 1
2 3 4 5 6 7 8 9 B
B 0 1 2 3
10 DCP_CLK
18 AD_BUSY
AD conversion board to main
11 DCP_DIN
19 AD_CLK
9 DCP_EN
6 AD_DIN
20 AD_RC
22 CH_A2
23 CH_A1
24 CH_A0
21 CH_A3
4 15GND
control board connection 17 15GND
25 GND
13 GND
14 +12V
1 +12V
5 GND
16 VCC
8 GND
12 NC
15 -12V
3 VCC
2 -12V
7 NC
BA40
BA40-
40-20-
20-73022
1 1 1 1 1 1 2 2 2 2 2 2
4 5 6 7 8 9 0 1 2 3 4 5
J13 1 1 1
1 2 3 4 5 6 7 8 9 1
0 1 2 3
A
Main control board BA40
61356
BA40-
40-30-
30- MINDRAY A
Pre-
Pre-amp board,
board, AD conversion
TITLE:
TITLE: board connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-16 6 Hardware
Figure 6-15 Connection diagram 5
1 2 3 4 5 6 7 8
PDB DDB
BA40-30-61361 BA38-30-88045 Simulate power
2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 connection board
D J24
J27 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 BA38-30-88342 D
4
6
5
J2
1
3
2
Main control Main control board and DDB
board and PDB connection
FPGA_CONF_OE
RSTCTL_REAC
connection BA40-20-61642
RSTCTL_RES
yellow
blue
12VGND white
black
RSTCTL_RP
RSTCTL_ST
RSTCTL_RES
RSTCTL_RT
RSTCTL_AW
SPI_CLOCK
blue
RSTCTL_TC
RSTCTL_MP
red
RXD_REAC
TXD_REAC
BA40-20-61641
RSTCTL_SP
SPI_DATA
NCONFIG
RXD_RES
TXD_RES
NCONFIG
RXD_RT
RXD_RES
TXD_RT
Main control board
RXD_AW
REV2_O
TXD_RES
TXD_ST
TXD_RP
RXD_MP
TXD_AW
RXD_ST
RXD_TC
RXD_RP
TXD_TC
TXD_MP
REV1_O
REV2_O
REV3_O
REV4_O
REV5_I
RXD_SP
TXD_SP
SPI_CS
REV5_I
REV6_I
DCLK
ASDO
DATA
DCLK
ASDO
power cable
DATA
GND
GND
GND
GND
NCE
NCS
GND
GND
GND
12VGND
GND
GND
GND
GND
NCE
NCS
GND
GND
GND
BA38-20-88354
GND
+12V
-12V
+5V
33
29
31
34
21
11
13
23
10
12
20
24
28
32
11
14
22
25
26
27
30
10
15
9
16
5
19
33
34
8
9
29
31
6
7
18
21
23
25
27
17
12
20
24
28
32
13
22
26
30
14
5
16
2
6
7
15
1
3
4
17
18
19
3
2
4
5
6
4
6
5
2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34
J10 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 J6 1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 J1
1
3
2
C C
7 PC_RESET
red
10 DCP_CLK
18 AD_BUSY
11 DCP_DIN
2 PC_RXD
19 AD_CLK
3 PC_TXD
ISE COM
9 DCP_EN
6 AD_DIN
20 AD_RC
22 CH_A2
23 CH_A1
24 CH_A0
21 CH_A3
4 12GND
17 12GND
1 red
5 GND
25 GND
13 GND
1 +12V
14 +12V
5 GND
16 VCC
8 GND
12 NC
NC
3 VCC
15 -12V
2 -12V
7 NC
10 NC
1 NC
4 NC
6 NC
8 NC
9 NC
2
ISE_TXD
3
ISE_RXD
4
NC
14 15 16 17 18 19 20 21 22 23 24 25 5 2 4 6 8 10
P1 GND 1 3 5 7 9
6
1 2 3 4 5 6 7 8 9 10 11 12 13 NC
7
ISE_CTS
8
Serial port
AD conversion board ISE_RTS connection port
9
BA40-30-61365 NC
10
NC
A A
Main control board connection
A-BA38-30-036 1.0
5 14
1 2 3 4 5 6 7
6 Hardware 6-17
Figure 6-16 Connection diagram 6
1 2 3 4 5 6 7 8
Sample level Reagent level Conflux DI water Wash solution
tube level high level low level
RM SM detection board detection board sensor sensor sensor
High-
High-conc DI water low
BA40
BA40-
40-30-
30-61369 BA40
BA40-
40-30-
30-61369 waste sensor level sensor
BNC
Wash unit up/
up/down stepper motor J2 J2
1
Mixer DC motor connection
connection
2
1
2
1
2
1
1 2 3 4 1 2 3 4 BNC
sensor connection
6brown B- 4brown
blue
BA38-20-88177
green
board connection
blue
2
1
2
1
red
6
BA38-20-88175
1 LEVEL green 3
board connection
green 3
black 1
2 RAM_V_PHO 2
BA38-20-88173
red 4
4orang
2 RAM_V_PHO 2
red 4
black 1
D Wash unit up/
up/down 4 e
B+ 3orange
D
black
black
black
black
black
stepper motor 3yello
4 CONFLUX red
red
8 WATER_H red
A- 2yellow
10 WATER_L red
red
3 w
blue
blue
BA31
BA31-
31-21-
21-56814
1 1red A+ 1red
12 R EAG_L
1 LEVEL
2 +12V
2 +12V
2 GND
1 GND
2 +6V
2 +6V
1 GND
1 GND
6 THICK
11 GND
Wash unit syringe stepper motor connection PDB and pump/
pump /valve driver
3 GND
5 GND
7 GND
9 GND
NC
NC
BA38
BA38-
38-20-
20-88186-
88186-07 board connection
5 5brown B- 4brown BA38
BA38-
38-20-
20-88176
4orang
B+ 3orange 31~
31~34 VCC
7 9 11 13 15 17 19 21 23 25 27 29 31 33
8 10 12 14 16 18 20 22 24 26 28 30 32 34
Wash syringe motor 4 e 1 2 1 2 1 2 1 2
33 31 29 27 25 23 21 19 17 15 13 11 9 7
34 32 30 28 26 24 22 20 18 16 14 12 10 8
1 2 1 2 1 3 5 7 9 11 30 GND
29 RPV
( ) 2 2yellow A- 2yellow J30 J29
2
J21 J20 J23 J18 2 4 6 8 10 12 28 RPV
J4
1
27 RPV
1 1red A+ 1red
3
Reagent probe arm up/
up /down motor J22 26 RPV
2
25 GND
connection
4
24 RPV
J5
6BA38
BA 38-
38-20-
6brown20-88185-
B- -02
88185 4brown 23 PMIX
Pump/Valve driver
4orang 22 RPV
BA40-30-61373
Reagent probe arm 4 B+ 3orange 21 RPV
4
e 20 GND
1
up/
up/down motor 3yello 19 RPV
3 A- 2yellow
BA31
BA31-
31-21-
21-56816 w Interface:
Interface: J1~ J24,
24, J26~
26~ J32 18 RPV
boar d
2
17 P1S
1 1red A+ 1red
J7
FPGA AS:
AS: J1
J1 4
16 PIN
Reagent probe arm rotation motor
J1 4
15 GND
connection 14
FPGA JTAG : J2 P67S
67S
4
BA38
BA38-
38-20-
20-88185-
88185-03 13 P8S
C 6 6brown B- 4brown Spared probe clog detection interface:
interface: J17,
17, 12 11
POUT C
4orang
1
P45S
45S
Reagent probe arm 4 e
B+ 3orange J24 10 GND
9
rotation motor 3yello
2
V34S
8S
34
3 w A- 2 yellow Spared pump/
pump/valve board interface:
interface: J31 7S
V12S
12
J8
BA31
BA31-
31-21-
21-56814 3 V56S
56S
1 1red A+ 1red Spared level sensor interface:
interface: J19 6 VDI
5 GND
3 5
4 6
4
Spared wash syringe motor:
motor: J6
5 3
6 4
4
B- BA38
BA 38-
38-30-
30-87928 Spared overflow detection interface:
interface: J13 2 VRP
1 VSP
6 6brown 4brown
1
2
1
2
1
22 GND green A
collision detection sensor
7 9 11 13 15 17 19 21 23
8 10 12 14 16 18 20 22 24
BA31
BA31-
31-21-
21-56814
3
3
21
21 R_RAM_
RAM_PHO white E
1 1red A+ 1red 4 BA40
BA40-
40-21-
21-61735
20 GND black C
K
4
J28
6 6brown B- 4brown 4 C
4
16 GND black
4orang K
red 1 A Reagent up/ up/down home
2
Sample probe 4 B+ 3orange 15
14
VCC
GND green
e
3
J10
position sensor
up//down motor
up 3yello 13
3
13 RU
RU_
_PHO white E
3 A- 2yellow 4 C BA40
BA40-
40-21-
21-61732
2
BA31 12 GND
BA31-
31-21-
21-56816 w
2
black
K Sample probe horizontal
1 1red A+ 1red 11 VCC
10 GND
red 1
green A B
B Sample probe rotation motor
1
3 S_RAM_
9 RAM_ PHO white E
collision detection sensor
connection 4 C BA40
BA40-
40-21-
21-61735
BA38
BA38-
38-20-
20-88186-
88186 -05 8 GND black
6brown 4brown K
6 B- 2 Sample probe rotational
4
7 VCC red 1 A
3 5
4 6
6 GND green
Sample probe 4orang B+ 3orange 3 E home position sensor
4
J1 1
5 RR_
RR_PHO white 4 C BA40
BA40-
40-21-
21-61733
3
1
2
2
3 VCC red 1
1 3 5 7 9 11 13 15 17 19 21 23 25 27 29 31 33 35 37 39 2 GND green A position sensor
1 1red 1red 3 E
A+ 4 3 2 1 4 3 2 1 4 3 2 1 1 RU_
RU_PHO white 4 C BA40
BA40-
40-21-
21-61732
1
2 4 6 8 10 12 14 16 18 20 22 24 26 28 30 32 34 36 38 40
PDB and position sensor
connection 2
Mixer rotation motor connection
1 AWSR_PHO white 4
2 GND
3 VCC
5 R S_PHO white 4
6 GND
7 VCC
9 SS_PHO white 4
3
10 G N D
11 VCC
13 AWH_PHO w hite 4
3
14 G N D
15 VCC
17 H_RAM_PH O white 4 C
3
18 G N D
19 VCC
4
3 1 A W S_ P H O w h it e E
2
22 G N D
23 VCC
42 4 G N D
3 5 R M U _ P H O w h it e E
2
26 G N D
27 VCC
42 8 G N D
3 9 R M R _ P H O w h it e E
2
30 G N D
31 VCC
33 MU_PHO white 4 C
3
34 G N D
35 VCC
37 MR_PHO white 4
3
38 G N D
39 VCC
4 GND
8 GND
2
12 G ND
2
16 G ND
2
20 G ND
2
32 G ND
2
36 G ND
2
4 0 G ND
BA38
BA38-
38-20-
20-88179
6 6brown B- 4brown
1red
4orange B+ 3orange
1red
A- 2yellow
A- 2yellow
6brown B- 4brown
3orange
1red
Sample syringe motor
A- 2yellow
4orange B+ 3orange
Mixer up/down motor
6 6brown B- 4brown
BA38-20-88186-06
BA38-20-88185-04
BA38-20-88185-05
connection
connection 1
black 2
red 1
A+
green 3
b lack 2
r ed 1
4 4orange B+
A+
A+
gr een 3
BA38
BA38-
38-20-
20-88178
red 1
r ed 1
r ed 1
r ed 1
r ed 1
r ed 1
r ed 1
r ed 1
gr e en A
gr e en A
gr e en A
gr e en A
gr een A
gr een A
gr een A
gr een A
blac k
blac k
blac k
blac k
blac k
blac k
blac k
bl a c k
3yello
3yello
3yello
w
1 1red
1 1red
1 1red
w
C
E
A
K
C
E
A
K Reagent syringe home
C
E
K
C
K
C
K
C
E
K
MINDRAY
c o
i s
BA31-30-41501
BA31-30-41501
BA31-30-41501
BA31-30-41501
BA31-30-41501
BA40-21-61732
BA40-21-61732
BA40-21-61733
BA31-30-41501
position sensor
position sensor
position sensor
position sensor
BA40-21-61733
position sensor
position sensor
on detection sensor
A A
sensor
6-18 6 Hardware
Figure 6-17 Connection diagram 7
1 2 3 4 5 6 7 8
D D
1 RXD_SP
J27 2 TXD_SP J10
C 3 RSTCTL_SP C
4 GND
PDB power 5 RXD_AW
1
2
1
2
6 TXD_AW
cable
3
4
3
4
7 RSTCTL_AW
BA40
BA40-
40-21-
21- 8 GND
5
6
5
6
1 6 9 RXD_RP
61705 10 TXD_RP
7
8
7
8
2 7 11 RSTCTL_RP
0
1
0
1
9
+24V yellow
+24V yellow
GND black
12 GND
+12V blue
-12V white
GND black
GND black
GND black
red
BA38-30-88044
GND black
3 8 J3 13 RXD_MP
1
1
2
1
1
1
2
1
4 9 14 TXD_MP
3
1
4
1
3
1
4
1
15 RSTCTL_MP
+5V
16 GND
6
1
6
1
5
1
5
1
5 10 PDB 17 RXD_RES
10
8
1
8
1
7
1
7
1
9
2
3
4
1
5
6
7
8
18 TXD_RES
BA38
BA38-
38-30-
30-87928 19
0
2
0
2
9
1
9
1
20RSTCTL_RES
GND
1 2 3 4 5
2
2
2
2
1
2
1
2
J14 21 REV1_O
6 7 8 9 10 22 REV5_I
4
2
4
2
3
2
3
2
23 REV2_O
6
2 2
6
2 2
5 7
2 8
5 7
2 8
24 GND
Power board 25 REV3_O
2
BA40
BA40-
40-30-
30-61627 26 REV6_I
0
3
0
3
9
2
9
2
B 27 REV4_O B
28 GND
2
3
2
3
1
3
1
3
29 DCLK
3
3
4
3
3
3
4
3
30 NCONFIG
31 ASDO
32 DATA
33 NCS
34 NCE
A
MINDRAY A
6 Hardware 6-19
Figure 6-18 Connection diagram 8
1 2 3 4 5 6 7 8
D D
400ul
400ul reagent probe
Sample probe assembly
assembly
BA40
BA40-
40-30-
30-61525
BA40
BA40-
40-30-
30-73133
black
black
red
red
2 SIGN
2 SIGN
1 GND
1 GND
J1 1 2 J1 1 2
J2 1 2 3 4 J2 1 2 3 4
black 1
black 1
blue 2
blue 2
1 LEVEL green 3
1 LEVEL green 3
red 4
red 4
Sample level detection board and Reagent level detection board and
2 RAM_V_PHO
2 RAM_V_PHO
PDB connection PDB connection
BA38
BA38-
38-20-
20-88173 BA38
BA38-
38-20-
20-88174
2 +12V
2 +12V
1 GND
1 GND
1 2 1 2 1 2 1 2
A
MINDRAY A
TITLE:
TITLE: Level detection board connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-20 6 Hardware
Figure 6-19 Connection diagram 9
1 2 3 4 5 6 7 8
barcode connection
BA38-20-88168
BA38-20-88169
BA40
BA40-
40-30-
30-61994 BA40
BA40-
40-30-
30-61986
connection
D D
red
red
10 mask
10 mask
5 GND
8 TRIG
8 TRIG
5 GND
2 RXD
2 RXD
3 TXD
3 TXD
7 RTS
7 RTS
1 VCC
1 VCC
6 CTS
6 CTS
9 NC
9 NC
4 NC
4 NC
DDB and reaction disk stepper motor connection
BA38
BA38-
38-20-
20-88185-
88185-01 J11 J12
1 1
6 6brown B- 4brown
1
2 4 6 8 2 4 6 8
Reaction disk 0 0
5orangeB+ 3orange 1 3 5 7 9 1 3 5 7 9
5
J3
rotation motor 2
2yello
A- 2yellow
3
w
BA38
BA38-
38-21-
21-88094 1 1red A+ 1red
4
1 RXD_TC
2 TXD_TC
J24 3 RSTCTL_TC J6
4 GND
DDB and reagent disk stepper motor 1 2 5 RXD_RES 1 2
connection 3 4
6 TXD_RES
7 RSTCTL_RES 3 4
C BA38
BA38-
38-20-
20-88186-
88186-03 8 GND C
5 6 5 6
1
6brown B- 4brown Interface:
6 Interface: J1 ~ J27,
27, J31 9 RXD_ST
Reagent disk 4orange B+ 3orange
7 8 10 TXD_ST 7 8
2
4 1 1
J4
FPGA AS: 11 RSTCTL_ST
rotation motor AS: J18 9 9
BA38-30-88044
3 A- 1 1
BA38
BA38-
38-21-
21-88094 1
1red
A+
1red 4 FPGA JTAG:
JTAG: J19 11 2
1
13
14
RXD_RT
TXD_RT
11 2
1
DDB Spared interface:
interface: J13 ~ J16,
16, J21,
21, 3
1 4
1 15 RSTCTL_RT 3 4
1 1
16 GND
BA38
BA 38-
38-30-
30-88045 J25 15 16 17 RXD_REAC 15 16
71 82 18 TXD_REAC 71 82
DDB and sample disk stepper motor 19 RSTCTL_REAC
connection 29 20 20 GND 29 20
12 22 21 FPGA_CONF_OE 12 2
BA38
BA38-
38-20-
20-88186-
88186-02 22 REV5_I
2
1
6 6brown B- 4brown 2 4
3 2 23 REV2_O 2 4
3 2
Sample disk
2
25 SPI_CS
rotation motor 7 38 7 38
3
26 SPI_CLOCK
1 1red A- 2yellow
2 27 2
BA38
BA38-
38-21-
21-88094 1red 3 03
9 SPI_DATA 93 03
4
3 3yellow A+ 28 GND
3 2
1 3 29 DCLK 1
3 23
3 4 30 NCONFIG 3 4
31 ASDO
B B
32 DATA
33 NCS
J8 34 NCE
J1 J22
1 2 3 4 5 6 1 2 3 4 DDB and main control
1 2 3 4
7 8 9 10 11 12 5 6 7 8 board connection
BA40
BA40-
40-20-
20-61642
2 R_FAN yellow
black
red
DDB and power board
DDB and power board
control connection
1 BA40-21-61749
3 P_FAN
BA40-20-61748
(NC)
1 GND
4 VCC
BA40-20-61750
8 SIGN yellow
4 +5V blue
3 GND blue
11 GND black
12 GND black
yellow
7 GND black
8 GND black
9 GND black
10 GND black
2 SIGN black
4 SIGN black
5 +12V white
5 GND white
red
1 +24Vyellow
2 +24V yellow
6 -12V brown
6 SIGN brown
connection
3 +24Vyellow
7 SIGN
mask
A
1
J14
2 3 4
MINDRAY A
1 2 3 4 5 6 1 2 3 4
J15 J1 Reagent TITLE:
TITLE: DDB connection 1
7 8 9 10 11 12 5 6 7 8
File:
File: Bytes:
Bytes:
refrigeration board
Power board BA40
BA40-
40-30-
30-61371 DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time: BA40
40-
BA40-30-
30-61627
Software & Rev:
Rev: Microsoft office Visio 2003
SHEET 9 OF 14 SIZE A3
A3
1 2 3 4 5 6 7
6 Hardware 6-21
Figure 6-20 Connection diagram 10
1 2 3 4 5 6 7 8
D D
Slip ring
BA38
BA 38-
38-21-
21-
WHT- YEL) 15
14
BLU) 17
GRN) 16
white-orange( WHT-
4 B_REA white-brown( WHT- BRN) 12
RED) 13
blue( BLU) 7
brown( BRN) 2
yellow( YEL) 5
green( GRN) 6
9
4
orange( ORN)
gray( GRY)
white-blue( WHT-ORN)
white-red(
WHT-
DDB and slip ring connection DDB and slip ring connection 2
1 BA38
BA38-
38-20-
20-88184
88184
3 white-yellow(
white-green(
BA38
BA38-
38-20-
20-88183
1 SYNC_AD_REA
5 CLK_AD_REA
3 DIN_AD_REA
DOUT_AD_REA
6 Heat_dish1
BUSY_AD_REA
4Heat_dish2
2Heat_dish3
10 AGND
+24V
2 A_REA
+24V
5
9 +12V
6 GND
NC
7
8
DDB and position sensor
1 connection
C NC C
2 BA38
BA38-
38-20-
20-88172
Preheat temp control board and DDB 1 3 5 7 9
1 3
NC
2 3 4 5 6 NC
connection 4
2 4 6 8 10 NC
BA38
BA38-
38-20-
20-88170 5 NC
J21 J10 6 NC
1 2 7 NC
8 NC
3 4
2
1
4 1 9 VCC 1red
SYNC_ADT_AU 5 6 A Sample disk home
2
10
1
ST_PHO 4white
4
3
8 A_AU 2 C
3 7 8 11 GND 2black K position sensor
DIN_ADT_AU 3 12 3green
BA38-20-88228
GND E
4
3
10 B_AU 4 1 BA40
BA40-
40-21-
21-61760
6
5
Preheat temp
control board
6 CLK_ADT_AU 5 9
0 13 VCC 1red
1 1
6
5
6
8 10 12 14 16 18 20
7
12 C_AU
7 14 STC_PHO 4white ACSample disk encoder
7 BUSY_ADT_AU
J20 11 2
1 15 GND 2black K sensor
8 10 12 14
7
8
9 11 13 15 17 19
5 DOUT_ADT_AU
NC 9 DDB 3 1
1 4 16 GND 3green E BA40
BA40-
40-21-
21-61761
J5 13
9 11 13
A
BA38
BA38-
38-20-
20-88171
11
6
VCC
VCC
2white
1black
connection
BA40
BA40-
40-21-
21-61522
Preheater temp switch connection
MINDRAY A
12 VCC 2green BA40
BA40-
40-21-
21-61659
TITLE:
TITLE: DDB connection 2
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-22 6 Hardware
Figure 6-21 Connection diagram 11
1 2 3 4 5 6 7 8
BA38-21-88189
3 connection 2
DIN_AD
3 SENSOR 12 black( BLK) 1
BA38
BA38-
38-21-
21-88163 3
15 16
13 CLK_AD blue( BLU) 7
C 17 18 C
GND white-red( WHT- RED)
14
19 20 13
GND White-purple( WHT - VIO) 18
(Fixed to reaction 15
blac GN
1 1 GND
disk with M3
M3 pan k D
J4
16
head screw)
screw) Reaction disk 2 17 VPP gray( GRY) 9
grounding cable
18 VPP
BA38
BA38-
38-20-
20-88223
19 GND
20 GND
A
MINDRAY A
Reaction disk temperature
TITLE:
TITLE:
control board connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6 Hardware 6-23
Figure 6-22 Connection diagram 12
1 2 3 4 5 6 7 8
D D
1 SHIELD 1
Preheat sensor 1 connection 2 REF
Preheat temperature control board and
BA38
2 J1
BA38-
38-20-
20-88221 3 SENSOR DDB connection
3
BA38
BA38-
38-20-
20-88170
2
1
4 SYNC_ADT_AU 1
2
1
4
3
8 A_AU 2
3 DIN_ADT_AU 3
1 SHIELD 1
4
3
10 B_AU 4
6
5
Preheat sensor 1 connection 2 REF J2 Preheat temperature control 6 CLK_ADT_AU 5
6
5
6
8 10 12 14 16 18 20
7
2 12 C_AU
C BA38
BA38-
38-20-
20-88221 3 SENSOR board 7 BUSY_ADT_AU 7
8 J20 C
9 11 13 15 17 19
8 10 12 14
7
5 DOUT_ADT_AU
DDB
3 BA38
BA38-
38-20-
20-88228 J5 13
NC 9
9 11 13
GND 10
11 +12V 11 BA38
BA38-
38-30-
30-88045
14 AGND 12
NC 13
NC 14
1 SHIELD 1
Environment temperature J3
2 REF
sensor connection 2
3 SENSOR
BA38
BA38-
38-21-
21-88224 3
B B
A
MINDRAY A
Preheat temperature control
TITLE:
TITLE:
board connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-24 6 Hardware
Figure 6-23 Connection diagram 13
1 2 3 4 5 6 7 8
Semi
Reagent refrigeration conductor Semi conductor Semi conductor Semi conductor
temperature sensor refrigeration refrigeration chip refrigeration chip refrigeration chip
connection chip connection connection connection
D BA30
BA30-
30-21-
21-15175 BA30
BA30-
30-10-
10- BA40
BA40-
40-21-61655
61655 BA40
BA40-
40-21-61655
61655 BA40
BA40-
40-21-61655
61655 D
2 black
2 black
2 black
2 black
2 black
1 red
1 red
1 red
1 red
1 red
BA38-20-88220
chip connection
Reagent refrigeration sensor
and reagent refrigeration
Contro
Contro
Contro
Contro
l end
VCC
l end
VCC
l end
l end
VCC
VCC
chip connection
BA40
BA40-
40-20-
20-61648
2 black
1 black
3 black
2 black
4black
1 red
5 red
6 red
7 red
8 red
Reagent refrigeration chip 1 2 3 4
power cable 1 1 2
BA40
BA40-
40-20-
20-61586 5 6 7 8
J1
1 24V red
1 1 J3
blac
2 FGND
2 k 2
C
J9 3 12VFAN yellow
J12 C
3
BA40-30-61627
3
gree
Power board
4 SGND
4 n 4
BA38-30-88045
GN
1 black 1 black
blac 1 D 1
3 GND 1
DDB
k
2 yellow R_FAN 2 yellow
4 GND
blac
2 P2 2 2
k
J14 3
P_FA
3
3 N 3
B
DDB and fan error warning connection B
BA40
BA40-
40-20-
20-61750
2 yellow
1 black
1 black
1 black
1 black
1 black
2 red
3 red
2 red
2 red
4 red
Refrigeration fan and reagent
3
Lamp fan and reagent
2
P_FAN (air pump fan
refrigeration board
refrigeration board
refrigeration board
0-88188
0-61644
BA40-20-61650
warning)
warning)
connection
connection
connection
DATA
VCC
VCC
VCC
VCC
VCC
BA38-2GN
GN
GN
GN
BA40-2GN
D
D
D
2 yellow
1 black
1 black
1 black
1 black
1 black
2 red
3 red
2 red
2 red
2 red
2
1
Anti-
Anti-fog
Refrigeration fan Anti-
Anti-fog heater
Lamp fan PCB fan connection PCB fan connection temperature switch
connection connection
M07-
07-00062S
00062S--- BA40
BA40-
40-21-
21-61653 BA40
40--21-
BA40 21-61653 connection
BA40
BA40-
40-20-
20-61649 BA40
BA40-
40-21-
21-61643
BA40
BA40-
40-21-
21-61645
A
MINDRAY A
Reagent refrigeration board
TITLE:
TITLE: connection
File:
File: Bytes:
Bytes:
DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6 Hardware 6-25
Figure 6-24 Connection diagram 14
1 2 3 4 5 6 7 8
Pump/
Pump/Valve driver board and PDB
cable
Pump/
Pump/Valve driver board and
BA38
BA38-
38-20-
20-88176
D power board connection D
BA38
BA38-
38-20-
20-88182 1 VSP
1 +12V
J4 2 GND J2 2 VRP
3 VOUT
BA40-30-61627
4
1 2 3 +12V
1 2 J14
Power board
P23S
23S
4 GND
3 4 1 2 5 GND
5 +12V 3 4 6 VDI 1 2
6 GND 3 4 7
5 6
7 +12V 5 6 J1 V56S
56
8S 3 4
7 8 8 GND 7 8 5 6 V12S
9S
12
5 6
1 9 +24V 1 7 8 V34S
34S
9 9 10 GND
7 8
0 10 GND 0 1 11
1 1 1 1 9 P45S
45S 1
11 +24V 0 12 POUT 9
1 2 12 +24V 1 2 1 1 0
13 P8S 1 1
11 2
BA38-30-87928
1 14
P67S
67S
11 2
1
3 4
1 1 15 GND
16 PIN
3
1 4
1
Pump/
Pump/Valve driver board 15 16
PDB
15 16
17 P1S
71 82 18 SIGN
and valve connection 19 71 82
1 2 9 20 SIGN
BA38
BA38-
38-20-
20-88180 2 20 GND
9 20
Sample probe int red 12V
12V 11 3 4 21 2
2 2
1 2 SIGN
22 1
2 2
black VSP 12
valve 5 6 SIGN 2
red 12V
12V 15 2 4
3 2 23 PMIX 34
C black VOUT 7 8 24 22 C
Probe ext wash valve 16 1 25 26 SIGN
9 25 GND 25 26
0 7 38 26
Phase 1, 2 injection red 12V
12V 17
1 1 2 SIGN 7 38
black V12
V12S
12S 18 27 2
valve 11 2
1 3 03
9 SIGN
28 9 0
Phase3
Phase3, 4 injection red 12
12V
V 19 SIGN
29 3 3
black V34
V34S
34S 20 3 4
1 1 3 2
1 3
3 2
1
SIGN
valve 30 GND 3
3 4
Reagent probe int red 12V
12V 21 15 16 31 VCC 3 4
valve
black VRP 22
71 82 Pump/
Pump/Valve driver board 32 VCC
J9
Phase5
Phase5, 6 injection red 12
12V
black V56
V
V56S
56S
23
24 29 20
BA40
BA40-
40-30-
30-61373 33 VCC
34 VCC
valve 12 22
3
2 42
25 26
7 38
2
3 0
9 3
3 2
1 3
3 4
Pump/
Pump/Valve driver board
and pump connection
B BA38
BA38-
38-20-
20-88181
88181 B
A
Phase 1 waste pump
red 12V
12V
black P1
P 1S
21
22
5 6
MINDRAY A
Pump/
Pump/Valve driver board
TITLE:
TITLE: connection
File:
File: Bytes:
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DWG NO.
NO. A-BA38
BA38-
38-30-
30-036 REV 1.0
Date:
Date: Time:
Time:
6-26 6 Hardware
6.9 Board Indication Light
Table 6-2 Indication Light for Each Board
Indication
light board Light on Light off Remark
mark
Main board (BA40-30-61356)
5V power works 5V power works
D16_+5V
normally abnormally
+12V power works +12V power works
D4_+12V
normally abnormally
-12V power works -12V power works
D7_-12V
normally abnormally
3.3V power works 3.3V power works
D3_3.3V
normally abnormally
Three-disk driver board (BA38-30-88045)
24V power works 24V power works
D22_+24V
normally abnormally
5V power works 5V power works
D20_+5V
normally abnormally
-12V power works -12V power works
D23_-12V
normally abnormally
12V power works 12V power works
D21_+12V
normally abnormally
3.3V power works 3.3V power works
D19_+3.3V
normally abnormally
Analog 5V power Analog 5V power
D30
works normally works abnormally
D31 Preheat heater on Preheat heater off
D32 Preheat heater on Preheat heater off
D33 / / Spared
D34 / /
D35 / /
D36 Reaction disk heater Reaction disk heater
on off
D38 / / Spared
D39 / / Spared
D40 / / Spared
Three-probe driver board (BA38-30-87928)
3.3V power works 3.3V power works
D1
normally abnormally
-12V power works -12V power works
D2
normally abnormally
5V power works 5V power works
D3
normally abnormally
C12V power works C12V power works
D4
normally abnormally
24V power works 24V power works
D5
normally abnormally
Spared mixing unit
D8 / / MUC working
indication
Spared sample probe
D9 / / unit MUC working
indication
6 Hardware 6-27
Spared reagent probe
D10 / / unit MUC working
indication
Spared wash unit
D11 / / MUC working
indication
051-000360-00)
Level detection board (051-000360-00
Level signal output
when conductive
D5 Level signal detected No level signal material contacts
probe, such as hand,
metal
Voltage control voltage Voltage control Adjust indication light.
D2 is greater than voltage is less than Adjust VR1 to change
reference value reference value D2 from on to off
Reaction disk temperature control board (BA38-30-87909)
12V power works 12V power works
D1
normally abnormally
Preheat temperature control board (BA38-30-88228)
5V power works 5V power works
D1_5V
normally abnormally
12V power works 12V power works
D2_12V
normally abnormally
Pre-amp board (BA40-30-61363)
No indication
light
AD conversion board (BA40-30-61365)
12V power works 12V power works
D13
normally abnormally
-12V power works -12V power works
D14
normally abnormally
5V power works 5V power works
D15
normally abnormally
Pump and valve driver board (BA40-30-61373)
J2 input 5V works J2 input 5V works
D1
normally abnormally
C12V power works C12V power works
D2
normally abnormally
24V power works 24V power works
D3
normally abnormally
J2 input 5V works J2 input 5V works
D28
normally abnormally
Reagent refrigeration board (051-000052-00)
12V FAN power works 12V FAN power
D2_12VFAN C12V
normally works abnormally
B12V power works B12V power works Reagent refrigeration
D3_12V
normally abnormally power supply
5V power works 5V power works
D4_5V
normally abnormally
24V power works 24V power works
D5_24V 24VFAN
normally abnormally
Reagent refrigeration Other status of
reagent refrigeration
D6 temperature sensor RED_LED
temperature sensor
temperature T>4
temperature
Other status of
Reagent refrigeration
reagent refrigeration
D8 temperature sensor YELLOW_LED
temperature sensor
temperature T<2
temperature
6-28 6 Hardware
Reagent refrigeration Other status of
temperature sensor reagent refrigeration
D7 GREEN_LED
temperature 2 temperature sensor
<T<4 temperature
Refrigeration chip is Refrigeration chip Foot 3, 4 connected
D9
working stand-by to J3
Refrigeration chip is Refrigeration chip Foot 1, 2 connected
D11
working stand-by to J3
12V power board (051-000509-00)
D20 5V output normal 5V no output
Refrigeration power
D21 B12V output normal B12V no output
supply
Power connection
24VLAMP output board converted to
D34 24VLAMP no output
normal light source power
supply
24Vpower board (051-000510-00)
LED1 A24V output normal A24V no output ISE power supply
Cooling fan power
LED2 24VFAN output normal 24VFAN no output
supply
LED3 B24V output normal B24V no output Motor power
Power connection board (051-000511-00)
Analog 12V output Analog 12V no
D20_D12V
normal output
Analog -12V output Analog -12V no
D14_-12V
normal output
Reagent refrigeration
D11_B12V B12V output normal B12V no output
power supply
Light source power
D10_A12V A12V output normal A12V no output
supply
D15_A24V A24V output normal A24V no output ISE power supply
Pump, valve, and fan
D12_C12V C12V output normal C12V no output
power supply
D13_5V 5V output normal 5V no output
D9_B24V B24V output normal B24V no output Motor power
Reagent refrigeration
D21_24VFAN 24VFAN output normal 24VFAN no output
fan power supply
6 Hardware 6-29
Figure 6-25 Main board
6-30 6 Hardware
Figure 6-26 Three-disk driver board
6 Hardware 6-31
Figure 6-27 Three-probe driver board
6-32 6 Hardware
Figure 6-28 AD conversion board
6 Hardware 6-33
Figure 6-29 Reagent refrigeration board
6-34 6 Hardware
Figure 6-30 Level detection board
6 Hardware 6-35
Figure 6-31 Pump/Valve driver board
6-36 6 Hardware
Figure 6-32 Reaction disk temperature control board
6 Hardware 6-37
Figure 6-33 Preheat temperature control board
6-38 6 Hardware
Figure 6-34 12V Power board
6 Hardware 6-39
Figure 6-35 24V Power board
6-40 6 Hardware
Figure 6-36 Power connection board
6 Hardware 6-41
For Your Notes
6-42 6 Hardware
7 Service and Maintenance
To ensure reliability, good performance and service life of the system, regular
maintenance is required. Be sure to follow the instructions given below to maintain
the system. Even you are only an operator, it is very important for you to learn this
chapter. Your thorough understanding will help you obtaining the best performance of
the system.
WARNING:
Do not perform any maintenance procedures that are not described
in this chapter.
Do not touch the components other than the ones specified in this
chapter.
Performing unauthorized maintenance procedures may damage your
system, void any applicable warranty or service contract and even
cause personal injury.
After performing any maintenance actions or procedures, ensure that
the system runs normally.
Do not spill water or reagent on mechanical or electrical components
of the system.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles during
maintaining process.
7.1 Preparation
The following tools, wash solution and ethanol may facilitate your maintenance.
WARNING:
Poisonous gas will be produced if acid wash solution is mixed with
alkaline wash solution. Do not mix the acid wash solution with the
alkaline one.
CAUTION:
Mindray has specified the following enhanced wash solutions:
Acid wash solution: 0.1mol/l hydrochloric acid;
Alkaline wash solution: Concentrated wash solution.
Be sure to use the enhanced wash solution specified by Mindray.
Otherwise, proper result may not be obtained.
Mindray recommends the acid and alkaline wash solutions be used
alternately. For instance, if the acid wash solution is used at current
startup, the alkaline one should be used at next startup.
1 Check DI water connector for leakage. If leakage does exist, plug the
tubing tight, and use clean gauze to wipe off the water.
4 Check and ensure water treatment system and pressure module are
powered on.
BIOHAZARD:
To prevent biohazard contamination, always wear gloves and lab coat
and, if necessary, goggles when checking the waste tubing.
Check if the waste drainage system works normally everyday. Ensure the waste
tubing is neither bent nor clogged, and the high-/low-concentration waste is handled
properly according to local regulations and rules for waste disposal.
CAUTION:
Ensure the waste tubing is neither clogged nor bent. Clogged or bent
waste tubing may lead to waste overflow that can damage your
analyzer.
2 Open the front doors of the analyzer. You will see the one reagent syringe
on the right and one sample syringe on the left.
Check whether the T-piece leaks.
3
If not, proceed to the next step.
If yes, check the cause. Replace tubing, T-piece, or connector if
necessary.
4 Check whether the plunger guide cap leaks.
If not, proceed to the next step.
If yes, replace the cap as instructed by 7.7.7 Replacing Syringe Plunger
Assembly.
5
Close the front doors of the analyzer.
1 On the Daily Maint. page, select System Reset and then click Execute to
clean the sample probe.
2 Check if the flow from inside the sample probe is continuous and in the
direction of the probe. Check the exterior of the sample probe to see
whether the flow is continuous and normal.
If not, clean the sample probe as instructed by 7.7.1.2 Unclogging
Sample Probe. If the flow remains abnormal, contact our customer
service department or your local distributor.
1 On the Daily Maint. page, select System Reset and then click Execute to
clean the reagent probe.
2 Check if the flow from inside the reagent probe is continuous and in the
direction of the probe. Check the exterior of the reagent probe to see
whether the flow is continuous and normal.
If not, clean the reagent probe as instructed by 7.7.2.2 Unclogging
Reagent Probe. If the flow remains abnormal, contact our customer
service department or your local distributor.
1 On the Daily Maint. page, select System Reset and then click Execute to
clean the mixer.
2 During the cleaning process, check whether the mixer rotates correctly
and water surge in the wash well of mixer works normally. If rotation is
abnormal, check if the mixer is bent or loose. If water surge is abnormal,
check if exterial wash connection is correct.
BIOHAZARD:
To prevent biohazard contamination, always wear gloves, goggles and
protective clothing when doing the below checks.
The cleaning solution is irritating to eyes and skin. Avoid contact with
skin and eyes. In case of contact with eyes, rinse immediately with
plenty of water and seek medical advice.
CAUTION:
Use the consumables recommended by Mindray. Other consumables
may degrade system performance.
Add solution supplied in the cleaning solution kit to top of label on the
powder bottle that is also supplied in the same kit and shake well to
prepare the cleaning solution.
The cleaning solution must be stored at 2-8C and discarded after two
weeks.
NOTE:
The maintenance is necessary to be performed when the ISE unit
(optional) is connected.
You should perform the maintenance once a day after all the samples
are analyzed. Besides, if the samples of a day requested for the ISE
tests are 50 or more, you should perform the maintenance after 50
samples are analyzed.
If you give the electrodes some time to stabilize after cleaning, you will
experience slightly better performance.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
2 Remove the cover from the sample compartment and remove the sample
disk.
3 Pull the sample probe arm to the highest point by hand. Rotate the probe
arm to move the sample probe to a position above the sample compartment
and convenient to operate.
NOTE:
We recommend the acid and alkaline detergents be used
alternately for this purpose. For instance, if the acid detergent
has been used for last maintenance, the alkaline detergent
had better be used for this time.
Use ethanol-dipped gauze to gently clean the exterior of the sample probe
until it is clean and smooth.
Wipe the sample probe with DI water-dipped gauze.
5
6 After cleaning, gently pull the probe arm to its highest point and rotate it to
move the sample probe to a position above the wash well.
CAUTION:
After cleaning the sample probe, be sure to move it to
a position above the sample probe wash well.
7 Install the sample disk, tighten the two retaining screws on it and then cover
the sample compartment.
8
Place the Power to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset the sample
probe and rinse it with deionized water.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
2 Uncover the reagent compartment and remove the reagent disk by pulling
upwards the handles.
4 CAUTION:
Do not contact the reagent probe directly with tweezers;
otherwise the reagent probe may be scratched. Excessive
force may bend the reagent probe.
NOTE:
We recommend the acid and alkaline wash solution be used
alternately for this purpose. For instance, if the acid wash
solution is used for last maintenance, the alkaline one should
be used for this time.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
2 Pull the mixer arm to the highest point by hand. Rotate the arm to move the
mixer to a position convenient to operate.
NOTE:
We recommend the acid and alkaline detergents be used
alternately for this purpose. For instance, if the acid detergent
has been used for last maintenance, the alkaline detergent
had better be used for this time.
Use ethanol-dipped gauze to gently clean the mixer until it is clean and
smooth.
Wipe the mixer with DI water-dipped gauze.
4
5 After cleaning, gently pull the mixer arm to its highest point and rotate the
arm to move the mixer to a position above the wash well.
6 Place the Power to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset the mixer
automatically and rinse it with deionized water.
CAUTION:
The mixer is precisely fabricated. In case of scratched or bent mixer,
replace it according to 7.7.6 Replacing Sample/Reagent Mixers.
CAUTION:
Do not stare at the laser of the bar code reader; otherwise your eyes
may get hurt.
2 Uncover the reagent or sample compartment, and remove the reagent disk
or sample disk.
3 Use the DI water-dipped gauze to wipe the bar code reader window.
5 Place the Power to ON. After about 30 seconds, the system will reset
automatically.
CAUTION:
Do not use sharp-edged tools to scratch the bar code reader window.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
2 Remove the cover from the sample compartment and remove the sample
disk by pulling upwards the handle.
3 Rinse the sample disk with fresh water and dry it with gauze.
5 Install the sample disk and tighten the two retaining screws on it. Then
cover the sample compartment.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
2 Uncover the reagent compartment and loosen the screws on the reagent
disk. Then remove the reagent disk.
3 Wash the reagent disk with fresh water and dry it with gauze.
5 Install the reagent disk and together the screws on it. Then cover the
reagent compartment.
WARNING:
The probe/mixer tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the probe/mixer.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used gauze in accordance with your local or national
guidelines for biohazard waste disposal.
Aside from the regular check, checking should be done after the replacement of
cuvettes and lamp.
3 Select Execute.
Cuvette check
4
The photometer check includes cuvette check and lamp check. Select
cuvette check first.
Time for cuvette check: 20 mins
NOTE:
To ensure the good performance of the photometer, replace
those cuvettes marked with red. Run cuvette check after
replacement, and save the data.
Place DI water in position W. Click Start. After 20-minute test, the cuvette
status will be refreshed according to the test result. Click Save to save the
result.
NOTE:
If Save is not selcted, the current test result will not be saved.
Next time when you enter this page, the cuvette status will be the
previous test result.
Click Results to view and print the latest ABS value of all the cuvette.
1 Enter the Daily Maint. page of the Utilities screen; then select Cuvette/Lamp
Check in the Maintenance area. Click Execute to enter Photometer Check
page.
NOTE:
Before running lamp check, replace those cuvettes marked with
red.
NOTE:
If Save is not selcted, the current test result will not be saved.
Next time when you enter this page, the lamp status will be the
previous test result.
In Lamp check page, you can view the latest two lamp check results. The
displayed value is the average of three consecutive cuvette aborsorbance.
When this value is greater than the calculated threshold value, the lamp
intensity is not strong enough. (The calculated threshold value can be queried
through Maintenance System Maintenance Light Source Setup.)
NOTE:
To ensure the good performance of the photometer, replace the
lamp when the light intensity is not strong enough.
5 After replacing lamp, if the value of water blank is greater than 63000, then
adjust the gain: adjust water blank to 47000~49000, with the gain parameters
in 340nm channel no less than 50. Refer to 4.7.3.3 for more information.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used cotton swabs in accordance with your local or
national guidelines for biohazard waste disposal.
2 Pull the sample probe arm to the highest point. Rotate the arm to move the
sample probe to a position above the sample compartment and
convenient to operate.
Clean the inside of and the place around the wash well with cotton swabs.
3
CAUTION:
After cleaning the sample probe, be sure to move it to
a position above the sample probe wash well.
5
Place the Power to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset and rinse
the sample probe automatically.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used cotton swabs in accordance with your local or
national guidelines for biohazard waste disposal.
2 Pull the reagent probe arm to the highest point. Rotate the arm to move
the reagent probe to a position above the reagent compartment and
convenient to operate.
3 Clean the inside of and the place around the wash well with cotton swabs.
After cleaning, gently pull the probe arm to its highest point and rotate it to
4
move the reagent probe to a position above the wash well.
5
Place the Power to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset and rinse
the reagent probes automatically.
WARNING:
The mixer tip is sharp and can cause puncture wounds. To prevent
injury, exercise caution when working around the mixer.
BIOHZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used cotton swabs in accordance with your local or
national guidelines for biohazard waste disposal.
2 Pull the mixer arm to the highest point. Rotate the arm to move the mixer
to a position convenient to operate.
3 Clean the inside of and the place around the wash well with cotton swabs.
4 After cleaning, gently pull the mixer arm to its highest point and rotate the
arm to move the mixer to a position above the wash well.
5 Place the Power to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset and rinse
the mixers automatically.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used cotton swabs in accordance with your local or
national guidelines for biohazard waste disposal.
WARNING:
The mixer tip is sharp and can cause puncture wounds. To prevent
injury, exercise caution when working around the mixer.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used cotton swabs in accordance with your local or
national guidelines for biohazard waste disposal.
3
Use clean gauze dipped with ethanol to gently wipe the wipe blocks of last two
phases, so as to wipe off dust and other contaminators.
Then use clean gauze dipped with deionized water to clean the wipe blocks
repeatedly, till the surface is clean and smooth.
NOTE:
Exercise caution. Excessive force may change the direction of
wipe blocks.
5
Push wash unit to move vertically with hand, to have it drop to top of cuvette.
Observe if the four sides of wipe block are level with the cuvette. If not, shift the
angle of wipe block on wash unit a little to make them level. The thinner part of
wipe block should face forward.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the damaged cuvette in accordance with your local or
national guidelines for biohazard waste disposal.
CAUTION:
Please use our recommended consumables. Other consumables may
degrade the system performance.
2 Loosen the knurled screws in the back of wash unit. Remove the wash unit.
3 Manually rotate the probes and mixers to a position convenient for cuvette
replacement and then remove the reaction disk cover.
Caution:
Exercise caution while unplugging, to avoid damaging wiring and
plug.
6 Take out the reaction disk carefully with both hands.
7 Use tweezers or hand to remove cuvettes to be replaced. Clip under two edges
of cuvettes to take out the cuvettes. Press the cuvettes into the bottom of their
position on the disk until no further can be pushed downward.
Caution:
Use tweezers to remove the old cuvettes when they are too tight.
Do not touch the optical surfaces of the new cuvettes.
Press the bullets tight when installing cuvettes.
8 Install the bullets
CAUTION:
Check for cuvettes and bullets that are forgotten to be installed.
9 Install the reaction disk back in the sequence opposite to step 2 to 6..
3 As shown in the figure below, remove the connector on the water tank cap,
loosen the cap, and then remove the water tank.
Warning:
Exercise caution. Excessive force may cause injury.
4 Wash the water tank for 2 to 3 times with fresh water, till the inner side is not
slippery or oily.
5 Install the water tank back. Turn on the analyzer to view if water tank works
normally.
3 Replace with new check valves and connect the tubing. If the end of the soft pipe
is deformed, cut off a small part of the pipe, and reconnect, so as to ensure
reliable connection.
4 Check if tubings are connected properly.
Pay attention to the direction of check valves when replacing. After replacing, two
check valves should guarantee the flow direction in the tubing as: D7D8, D9
D10, D3D11, D4D12. Refer to following figure for check valve flow direction:
3 Cut another pipe of the same length: first phase tubing is 650mm, and the second
is 600mm. Connect one end of the new tubing to the wash probe, and the other
passing through the tubing fixer to its respective adapter. (Be sure the old tubing
sign is added to the new tubing.)
4 Reinstall the back cover.
5 Perform startup initialization after replacing, to check the tubing for leakage.
You can unplug in this way: press down the releasing ring as indicated in
the picture with one hand, and pull out the connecting pipe with the other
hand.
NOTE:
Due to possible remaining pressure in inlet tubing, there may
be water spraying out when unplugging the connecting pipe.
Try to avoid water spraying onto the equipment. Wipe the
water off if this happens.
4 Install the connecting pipes onto both ends of new filter assembly
accordingly.
NOTE:
When installing the connecting pipe, make sure it touches the
bottom of the connector. Pull out the connecting pipe after
installing to check if it is installed properly.
Check direction before installing, with the arrow indicating
water flow direction pointing down.
NOTE:
When ball valve is turned on, there may be water coming off
the air outlet tubing. Please place properly to avoid overflow.
6
Turn on the Power of analyzing unit. Check if water supply is normal.
2 Wear rubber gloves. Take out a soft pipe (inner diameter: 1/8, length: 50mm)
from the supplies bag. Connect one end to new filter assembly, and the other to
disposable syringe. Inject water to the filter through the syringe till water comes
out of the filter. Take off the soft pipe and syringe. The purpose is to increase the
weight of filter assembly, so as to be placed at the bottom of wash solution
bucket.
3 Take the wash solution bottle cap out of the wash solution bucket. Remove the
old filter assembly from the bottle cap.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
2 Uncover the sample compartment and remove the sample disk by pulling
upwards the handle.
3 Pull the probe arm to the highest point. Rotate the arm to move the sample
probe to a position above the sample compartment and convenient to
operate.
4 Grab the lower part of the arm cover with two hands and pull them slightly
outwards and then remove the cover upward from the arm base.
Hold the sample probes fluid connector with one hand and the tubing
5
connector with the other. Rotate the tubing connector counter-clockwise
until it disconnects from the sample probe. Remove the tubing from the
probe.
6 Press the circuit board with one hand and disconnect the probes circuit
connector from the board with the other hand.
CAUTION:
Exercise caution when disconnecting the connector.
Excessive force may damage the connector and/or the circuit
board.
NOTE:
Exercise caution when pulling the sample probe away from
the arm so that the probe tip will not contact or even damage
the probe arm.
Slowly pull the probe away from the probe arm. Exercise caution so that
the gasket inside the probe does not drop out and if it does, store it in a
clean place for later installation. Replace the gasket if it has been
disassembled for 2 to 3 times. Otherwise leakage may occur or sampling
precision be affected.
NOTE:
The sample probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to 7.7.3
Replacing Sample Probe.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used needle in accordance with your local or national
guidelines for biohazard waste disposal.
CAUTION:
The sample probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to 7.7.3
Replacing Sample Probe.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
2 Insert the sample probe back into the hole on probe arm, and align the
hole on probe plate to the rotor inside the arm.
3 Sleeve the spring on the rotor and screw the retaining screw to secure.
4 Pinch the sample probe by the part near the probe arm. Gently push the
probe upward and then release the probe to see if the spring can move
freely.
If so, proceed to the next step.
If not, check for errors and try again after removing the errors.
5 Connect the sample probes circuit connector back to the circuit board.
Place a washer in the tubing connector, and then screw clockwise the
6
probes fluid connector back to the tubing connector.
CAUTION:
Exercise caution when connecting the sample probe.
Excessive force may bend the probe.
7 Place the Power to ON.
8 Adjust the level sensing board: Fill the clean open container with DI water.
Put the tip of the reagent probe 2-3 mm under the water level. The
indicator D5 on the level sensing board will go through a process of
OFF-ON procedure. After the tip of the reagent probe is taken way from
the water, the indicator D5 will go off, which shows the function of the
board is normal. Proceed to the next step.
9 Install the probe arm and make sure it is clicked properly into the arm
base.
10 Pinch the sample probe by the part near the probe arm. Gently push the
probe upward and then release it to see if the spring can move freely.
If so, proceed to the next step.
If not, check for errors and try again after removing the errors.
CAUTION:
After installation, be sure to move the sample probe to a
position above its wash well.
CAUTION:
The sample probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to 7.7.3
Replacing Sample Probe.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
CAUTION:
Exercise caution when disconnecting the connector.
Excessive force may damage the connector and/or the circuit
board.
NOTE:
Exercise caution when pulling the probe away from the arm
so that the probe tip will not contact or even damage the
probe arm.
Slowly pull the probe away from the probe arm. Exercise caution so that
the gasket inside the probe does not drop out and if it does, store it in a
clean place for later installation. Replace the gasket if it has been
disassembled for 2 to 3 times. Otherwise leakage may occur or sampling
precision be affected.
NOTE:
The reagent probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to
7.7.5Replacing Reagent Probe.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the used needle in accordance with your local or national
guidelines for biohazard waste disposal.
CAUTION:
The reagent probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to 7.7.5
Replacing Reagent Probe.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
2 Insert the reagent probe back into the hole on probe arm, and align the
hole on probe plate to the rotor inside the arm.
3 Sleeve the spring on the rotor and screw the retaining screw to secure.
Pinch the reagent probe by the part near the probe arm. Gently push the
4
probe upward and then release it to see if the spring can move freely.
If so, proceed to the next step.
If not, check for errors and try again after removing the errors.
5 Connect the reagent probes circuit connector back to the circuit board.
CAUTION:
Exercise caution when connecting the sample probe.
Excessive force may bend the probe.
CAUTION:
After cleaning, be sure to move the reagent probe to a
position above its wash well.
CAUTION:
The reagent probe is precisely fabricated for accurate
aspiration/dispensing. A bent or damaged probe will lead to unreliable
test results and should be replaced immediately according to 5.7.5
Replacing Reagent Probe.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
CAUTION:
Please use our recommended consumables. Other consumables may
degrade the system performance.
BIOHAZARD:
Dispose of the bent or damaged sample probe in accordance
with your local or national guidelines for biohazard waste
disposal.
CAUTION:
After installing the sample probe, be sure to rotate it to a
position above the wash well prior to sample disk installation.
WARNING:
The sample probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the sample
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
WARNING:
The reagent probe tip is sharp and can cause puncture wounds. To
prevent injury, exercise caution when working around the reagent
probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
CAUTION:
Please use our recommended consumables. Other consumables may
degrade the system performance.
BIOHAZARD:
Dispose of the bent or damaged reagent probe in accordance
with your local or national guidelines for biohazard waste
disposal.
CAUTION:
After installing the reagent probe, be sure to rotate it to a
position above the wash well prior to reagent disk installation.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the damaged mixer in accordance with your local or
national guidelines for biohazard waste disposal.
CAUTION:
Please use Mindray-recommended consumables. Other consumables
may degrade the system performance.
2 Prepare a new mixer. Wash the flat part of the new mixer with wash
solution-dipped gauze or cotton swabs and then wipe it with DI
water-dipped gauze.
3 Gently pull the mixer to its highest point and rotate it to a position
convenient to operate.
4 CAUTION:
When trying to pull out the mixer, concentrate your force in
the direction of the axis on the mixer arm. Biased force may
damage the mixer and/or the axis.
Pinch the mixer by the knurled part with one hand and unscrew
(counter-clockwise) the retaining nut with the other hand until the mixer
looses. Pull the mixer downward to remove it and remove the nut.
6 Pinch the mixer by the knurled part and align the hole of the nut to the axis
on the mixer and push the nut onto the mixer until it reaches the end of the
mixer. Tighten the nut by screwing clockwise with the other hand.
CAUTION:
When trying to push the mixer into the arm, concentrate your
force in the direction of the axis on the mixer arm. Biased
force may damage the mixer and/or the axis.
Ensure the mixer is all the way pushed to the end.
7 After replacing the bar, visually check whether the mixer is vertical to the
bar arm.
If not, return to step 5 to remove the mixer and reinstall it.
If so, proceed to the next step.
8 Pull the mixer arm to its highest point and rotate it back to a position above
its wash well.
CAUTION:
After installing the mixer, be sure to rotate it to a position
above its wash well.
9
Place the Power back to ON. Wait for about 30 seconds and then execute
System Reset on the Daily Maint. page. The system will reset
automatically.
WARNING:
The probe tip is sharp and can cause puncture wounds. To prevent
injury, exercise caution when working around the probe.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
CAUTION:
Please use our recommended consumables. Other consumables may
degrade the system performance.
Exercise caution when installing the plunger assembly. Excessive
force may crack the syringe.
Always wear gloves while replacing the syringe plunger assembly.
Plunger assembly of sample syringe can be replaced in the same way as that of
reagent syringe. Perform the following steps to replace the reagent syringe plunger
assembly.
2 Open the front doors of the analyzer. You will see the sample syringe on the
right and reagent syringe on the left.
3 Prepare a new plunger assembly (shown in the figure below) and soak the
plunger tip in deionized water to eliminate bubbles.
6 CAUTION:
There may be residual water in the syringe connector. Do not
drop water onto the analyzing unit.
Grab the T-piece with one hand and the syringe connector with the other
hand and unscrew (counter-clockwise) the syringe. Exercise caution so that
the gasket on the syringe does not drop out and if it does, store it in a clean
place for later installation. Replace the gasket if it has been disassembled for
2 to 3 times. Otherwise leakage may occur or sampling precision be
affected.
7
CAUTION:
There may be residual water in the syringe. Do not drop
water onto the analyzing unit.
The plunger rod of the syringe is slender. Exercise caution
when working on it. Excessive force may bend it.
Unscrew (counter-clockwise) the plunger guide cap and pinch the plunger
button to gently pull the plunger assembly from the syringe.
Pinch the new plunger assembly by the plunger button and carefully insert
the plunger tip into the syringe and push it all the way to the end. Screw
clockwise the plunger guide cap until secure.
9 Immerse the syringe connector into deionized water. Pinch the plunger
button, pull it to aspirate half syringe of deionized water and then push it to
expel the deionized water and the air from the syringe.
10 Grab the T-piece with one hand and the syringe connector with the other
hand. Screw clockwise the syringe with the gasket into the T-piece until
secure.
11 Place the syringe on the holder.
CAUTION:
Operation should follow the steps and cautions strictly, otherwise
there may be installation problems leading to syringe damage or
early invalidation.
12 Install space bars and fix four upper retaining screws. Do not tighten the
screws now.
Adjust the height of syringe to keep the V-shaped groove level with sample
syringe scale11 (or reagent syringe 7.5). Then tighten the screws.
13 Rotate syringe assembly motor. When syringe plunger moves downward till
the plunger goes out of the syringe for 10~15mm, gently rotate the plunger
retaining screws to push the front end of plunger connector close to the drive
part.
Gently tighten the plunger retaining screw to avoid plunger rod beat.
14 Place the Power back to ON. Wait for about 30 seconds, and then execute
System Reset on the Daily Maint. page. Repeat the instruction for several
times if necessary, and check if the T-piece is leaking.
If not, go to the next step.
If yes, tighten the syringe. If leakage remains, replace the T-piece and
connector.
15
Close the front doors of the analyzer.
BIOHAZARD:
To prevent biohazard contamination, always wear gloves, goggles and
protective clothing when doing the maintenance.
Dispose of the waste in accordance with your local or national
guidelines for biohazard waste disposal.
2 Unscrew the screws on the syringe cover and remove the cover. You can
see the reagent syringes on the left and sample syringe on the right.
3 Loosen the four upper retaining screws of the syringe, then remove the
screws and space bar.
4 Loosen the four lower retaining screws of the syringe and remove the
syringe from the holder.
5 Pull the plunger gently outwards until you can not proceed any more, and
then push it quickly. Repeat this pull-push operation until the air bubbles
are removed from the syringe.
CAUTION:
Be sure not to push the plunger to the end tip; otherwise the
syringe may be damaged.
6 Place the syringe on the holder. Install space bars and fix retaining screws.
NOTE:
th
The upper edge of the upper space bar must reach the 7
scale on the syringe.
When fixing the retaining screws, be sure to tighten them
alternately with equilibrium force.
1 Enter the Daily Maint. page of the Utilities screen; then select
Cuvette/Lamp Check in the Maintenance area and click Execute. Select
Replace Lamp on the Lamp Check tab page. Make sure that the lamp has
cooled down for 15 minutes,.
WARNING:
After working for a while, the lamp and its housing are usually
hot enough to burn you. Do not proceed with this procedure
until they have cooled down.
2 The light source assembly is at the right rear part of the instrument.
Unscrew the seven retaining screws on the back cover by using a screw
driver. Remove the back cover.
3 Unplug the fan power cable from the socket. Unscrew the two air duct
retaining screws by using a screw driver. Pull the air duct out.
5 Please wear the glove to protect the circuit boards from ESD. Press the
lever and then pinch the lamp base and pull out the lamp.
NOTE:
The larger pin is inserted into the larger hole and the smaller
pin into the smaller hole.
The lamp must be pressed to the bottom of the hole, otherwise
the performance may be affected.
Do not pinch the quartz lamp to aovid contaminating or
crushing the lamp.
7 Install the lamp housing radiator back. Tighten the screws at the lower part
of the housing.
8 Install the air duct back and tighten the retaining screws. Reconnect the fan
power cable.
9
Close the back cover of the analyzing unit and tighten the four retaining
screws.
WARNING:
The probe tip is sharp and can cause puncture wounds. To prevent
injury, exercise caution when working around the probe.
Before replacing cuvette rotate the probes to a position convenient for
operation.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
Dispose of the damaged cuvette in accordance with your local or
national guidelines for biohazard waste disposal.
2 Manually rotate the probes and mixers to a position convenient for cuvette
replacement and then remove the reaction disk cover.
3 Make sure which cuvettes need replacing. Rotate reaction disk with hand to
place cuvettes needing replacing at positions convenient to be removed.
4 Use tweezers or hand to remove cuvettes to be replaced. Clip under two edges
of cuvettes to take out the cuvettes. Press the cuvettes into the bottom of their
position on the disk until no further can be pushed downward.
Caution:
Use tweezers to remove the old cuvettes when they are too tight.
Make sure to use tweezers to clip on both edges of the cuvette so
as not to crush the cuvette.
Do not touch the optical surfaces of the new cuvettes.
Press the bullets tight when installing cuvettes.
6 Enter Daily Maint. page, and execute Cuvette/Lamp check. View the check
results and new cuvette status. If the new cuvette is still marked as dirty, check
the lamp and lens. Use anhydrous alcohol to clean the lens assembly. Replace
the lamp or fiber if necessary.
BIOHAZARD:
To prevent biohazard contamination, always wear gloves, goggles and
protective clothing when doing the maintenance.
Dispose of the waste in accordance with your local or national guidelines
for biohazard waste disposal.
1 Place the Power to OFF. Remove right plate, and then the failed pump.
CAUTION:
NF10 pump uses hexagon lobular socket pan head screws, which
should be removed with special hexagon offset ring screw driver.
See the figure below. NF30 pump uses cross batch.
Before disassemble the pump, it is better to make a sign on the
pump with a marker, so that the pump will not be misapplied when
installing back.
CAUTION:
Lip diaphragm cannot be cleaned with frewsh water, to prevent
water from entering the motor.
Install valve.
Note:
Place the valve into the groove of intermediate plate. Keep the valve upright, or
it will degrade the sealing effect of check valve.
Install the connection plate, swing valve and head plate. Locate the azimuth of
each part with sign marked earlier. Pay attention to the inlet and outlet sign of
the pump (inlet on the right, and outlet on the left).
Use tools (NF10 pump uses hexagon offset ring screw driver T6, and NF30
pump uses cross batch) to tighten the four head screws.
Note:
(1) The screws must be tightened, or the pump cannot be sealed, and water
cannot be pumped.
(2) Apply force both rotationally and vertically when tightening the screws
(press the screw tightly with screw driver), so as to avoid screw sliding.
7 Checking
Experiment on serviced pump (The liquid pump may not be installed to the
support during experiment. As long as the electrical cables and fluidic tubings
are connected, control with the software. Execute System Reset for NF10
pump. Remove the wash unit for NF30 pump, and put the wash blocks into an
open container filled with fresh water, and then execute System Reset.). If
pump works normally, install the pump to the pump/valve support and connect
cables as well as tubings. Repeat the procedure of disassembling, cleaning,
and installing when:
CAUTION:
Use the consumables recommended by Mindray. Other consumables
may degrade system performance.
NOTE:
Generally after the replacement of any of the following components,
several ISE calibrations should be run before ISE Unit become stable.
6 Execute Purge A Cycle and Purge B Cycle and check whether the
initialization of the Reagent Pack is finished. If no error occurs during the
process, the Reagent Pack is replaced successfully.
WARNING:
Before performing the replacement, make sure the analyzer is
powered off.
NOTE:
Because the electrodes must be installed sequentially, you
have to take out the electrode to be replaced and those (or
that) over it from above to below.
CAUTION:
The maintenance is necessary to be performed when the ISE unit
(optional) is connected.
The ISE unit (optional) should be on power all the time. In some cases
that the Power will be shut down for a long time more than half an hour,
the following steps should be performed.
Use the consumables recommended by Mindray. Other consumables
may degrade system performance.
4 Select Purge Combination from the Instructions list, and enter digit 25
in the edit boxes to the right of Purge A and Purge B. Select Execute to
start the purge cycle based on the parameters you have entered.
5 Select Maintenance Cycle from the Instructions list and select Execute.
6 Remove the electrodes.
7 Remove the Reagent Pack.
8 Put the reference, Na+, K+, Cl- and spacer electrodes into their individual
sealed bags.
NOTE:
The tube adapters on Reagent Pack should be covered by the red
caps. Store the Reagent Pack properly.
As needed.
Refer to
Mixer Mixer rotor Probe tip damaged, bent or 7.7.6
erosion
On right and Recommended 3 months.
Sample/Reagent
left side after Refer to
syringe plunger Or tested for 100,000 times.
opening front 7.7.7
assembly
door Or obvious damage
1 month suggested for
Reaction Inside plastic cuvette. Refer to
cuvette reaction disk Or reaction cuvette checked 7.7.10
and marked as damaged
Inside right
side board,
Replace when it serves for 6 Refer to
Check valve connection
months 7.6.1
point of
fluidics
Aspiration
Auto wash Replace when it serves for 6 Refer to
tubing of phase
tubing months 7.6.2
1 and 2
On the left
side of water
Replace when it serves for 6 Refer to
DI water filter tank after
months 7.6.3
opening front
door
Inside diluted
Wash solution Replace when it serves for 6 Refer to
wash solution
filter months 7.6.4
bucket
One on each
side of water As needed; Refer to
Water tank filter tank after
blocked 7.7.12
opening front
door
As needed;
Fluidic Refer to
Waste tubing Waste drainage is not
connection 7.7.13
smooth
Run Setup.exe file under Setup. Select Next when following screen is shown.
As following figure pops up, select folter to install the software. Then select Next.
System will finish the installation process automatically. Select a default language
when Select Language dialog box pops up. Then select OK to complete the
installtion.
The upper area provides various function buttons to test each unit.
The lower area displays the communication data associated with the main
unit/subunits. The lower-right area provides options and buttons to control the
communication frame.
ISE: Repeatedly overwrite and save all ISE information being sent and received.
ReacTempData.txt: Save data of reaction disk temperature test after latest run.
Disp.txt: Repeatedly overwrite and save all data frames that comply with the
communication protocol.
Shakehand: Select this command to shake hand with the main unit.
NOTE:
System reset: Select this command to reset the subunits of the analyzer.
Unit Version: Select this command to view the versions of main unit and
subunits.
Dark Current: Select this command to inquire the dark current at each
wavelength after the lamp is turned off.
Send instruction: Enter an instruction and select this command to send it.
Sleep: Select this command to make the main unit enter sleep status.
Search Log: Select this command to view the event logs of the main unit.
To vertical home position: Select this command to move the probe/mixer to its
vertical home position.
To ver. Limit of: Select this command to move the probe/mixer to its lowest
Into: Select this command to move the probe/mixer to the fixed position of
To liquid of : Select this command to move the probe/mixer to the liquid level
of or to the lowest vertical position in case of no liquid.
for steps: Select this command to move the probe/mixer for configured steps,
which are related to the parameter configuration of the unit.
Syringe empty: Select this command to move the syringe to the home position.
Syringe reset: Select this command to move the syringe to the zero position and
then to the home position.
Syringe full: Select this command to move the syringe to the obverse limit
position.
Reset reagent/sample disk: Select this command to reset the reagent/sample disk
unit. (This command is similar to that of other units.)
Rotate to given position: Select this command to rotate the reagent/sample disk at
specified speed for given circles and then stop it on specified position.
Find zero position: Select this option to rotate the reagent/sample disk to the
zero position and then rotate it at specified speed for given circles and then stop
it on specified position.
Rotate obversely: Select this option to rotate the reagent/sample disk
clockwise.
Rotate for given positions: This command is similar to Rotate to given position
except that the reagent/sample disk rotates for given positions and then stops.
Rotate and measure: Select this command to rotate the reaction disk at highest
speed for one circle and then stop it on position 2. During the rotating, photometric
measurement is performed.
Adjust lamp: Select this command to adjust the brightness level (0-255) of the lamp.
The two commands Rotate to given position and Rotate for given positions
are similar to that of the reagent disk unit.
Understand completely the relationship among all valves and their functions.
NOTE:
Before turning on int. wash pump, please ensure that at least one of
sample or reagent int. wash valve is turned on. Otherwise there are
hazards of damaging these pump and valves, or tubing falling off under
pressure.
Step Instructions
Click any command in this area. The corresponding operation will be performed.
Manually Instruction
Multiple buttons in this area should be used during a complete test. The following
operation combinations are available:
The commands in this area can be performed circularly. On the left is the circular
command control area and on the right is the instruction area.
Debugging
The commands provided in this area are used to debug the ISE unit and can be
operated in the same way as the Step Instructions.
This section introduces the screen operations of the Bar Code tab.
1. Select a bar code type: Sample Bar Code or Reagent Bar Code.
Scanning test
1. Select a scan mode, which includes Dynamic, Dynamic and Static, and Static.
During scanning, you can select Pause, Resume or Stop to control the
operation.
Judge the scanning result.
All instructions that are sent or received are displayed in the box on
right-hand side of the screen. You can save or clear the instructions if
needed.
Testing scanning stability
This operation is similar to the scanning test except that the options like scan mode
and start position must not be configured.
Sending instructions
Enter the original command and select Send Instruction to send it directly.
This chapter introduces the functions of the Reaction Disk Temp. screen.
1. Set up the times of taking temperature and power readings and the interval
between two readings.
3. Select Start to start taking the temperature and power readings. During the
reading process,
You can stop or pause the taking operation, and then save and load history
readings.
You can adjust dynamically the Y-coordinate range of the temperature
curve.
You can zoom in the curve display area as needed.
The temperature data since the current startup are saved in the directory
where the test and maintenance software locates.
Checking sensor parameters and configuring the parameters
3. Select Self-adjust to notify the corresponding subunit to start adjusting the PID
parameters.
Select Heater on or Heater off. If the command is not executed correctly, select it
again.
The Photoelectric Unit screen provides a function that enables you to perform the
following three tests for photometric measurement:
1. Select the check box next to Reaction disk rotates and deselect Measure 72
cuvettes.
2. Set up the cuvette position to measure, times and interval for collecting data.
3. Select Start. The AD values at each wavelength for the cuvette are displayed in
tabular and graphic forms.
1. Deselect the check boxes next to Reaction disk rotates and Measure 72
cuvettes.
2. Set up the cuvette position to measure, times and interval for collecting data.
4. Select Start. The AD values at each wavelength for the cuvette are displayed in
tabular and graphic forms.
NOTE:
After executing this command, you must reset the photoelectric unit
mechanically.
2. Set up the cuvette position to measure, times and interval for collecting data.
On the left side of the screen is the Instruction area, in which you can view the
detailed instructions of specified unit. See Figure 8-12.
2. Select New.
3. Enter the name of the new macro instruction in the popup dialog box, then select
OK. The name appears in the drop-down list box next to Name.
2. Select a command.
3. Method: Select desired unit and instruction type in the Instruction area. All
qualified instructions of the unit are displayed in the lower table.
5. Enter instruction value in the Value column according to other information in the
table. Note:
Select Add to Macro. The selected command is added to the macro instruction
list on the right-hand side of the screen. Repeat steps 1) through 5) to add more
commands.
8. Select Save below the macro instruction list to save the macro instruction. The
newly-created macro instruction is temporarily stored in the memory. If not
saved, the macro instruction will disappear when you switch to other one or exit
the system.
Select a command. The table in middle of the screen shows the detailed
information of the command.
Change the Value of each byte, or reselect a unit name and instruction type to
replace the instruction of the selected No. in the macro instruction list.
4. Save the macro instruction. Select Save to save the macro instruction to the
database.
2) Enter the No. of the desired byte of the command in the Instruction Details
area.
3) Enter the delay time in the Delay field, which can be neglected if no delay is
needed before the command is executed.
4) Enter other parameters like low limit, high limit and step. In case the macro
instruction is cycled for many times, when the command is executed, the
corresponding byte of the selected No. will be increased according to the
defined low limit and step until the high limit, then the byte of the low limit (No.)
starts running again.
NOTE:
The delay information and byte control information can exist
simultaneously or by themselves.
8.3 Parameter
Select the Parameter from the main screen. The Parameter screen is displayed. You
can inquire and configure the parameters of the main unit and subunits. For the
probe/disk/mixer units you are allowed to set up the motor speeds. See the figure
below.
2. Select Inquire.
Configure/Configure All
1. Inquire or read the parameters of selected unit/motor.
3. Select Config. To configure the parameter of the modified line, or select Config.
All to configure all parameters of the selected unit/motor.
Save
1. Inquire or read the parameters of selected unit/motor.
Read
1. Select a target unit.
2. Select Read, then select a parameter file in the popup dialog box. If you select a
parameter file of a unit other than the target one, the latter will be replaced by
the unit specified in the parameter file.
Restore
This button is similar to Read, except that when selecting Restore you must not
select a target file, and the system will read the target file from the directory where the
test and maintenance software locates.
During service, the most basic application is the repeated operation of running
checking debugging running checking. Take the debugging process after
replacing reagent disk drive assembly as example, to introduce the three steps of
running, checking, and debugging.
8.4.1 Running
After the reagent disk drive assembly is replaced, service personnel should adjust
reagent disk stop position. So it is necessary to perform following operations:
Then execute Reagent Probe Unit To top of outer reagent disk to rotate reagent
probe to top of outer circle of reagent disk.
8.4.2 Checking
Check to see if reagent probe is levelled to center of reagent bottle in the direction of
reagent disk rotation. If not, determine whether reagent disk should continue to rotate
clockwise or counter-clockwise.
8.4.3 Debugging
Inquire reagent disk parameters in Parameter screen.
Adjust Cuvette position offset (Stop position) based on the checking result.
Increase the value means counter-clockwise adjustment of reagent disk stop position;
otherwise, clockwise adjustment.
Note: Generally, the analyzer parameters are adjusted to optimal status at release.
Therefore, the adjustment range for each time should not be too large.
Repeat the process introduced above, till it is adjusted to the position where reagent
probe is leveled with center of reagent bottle.
This chapter provides the system warning messages and recommended corrective
actions, which should be taken in time once any error occurs.
When an error or failure occurs, relevant alarm message will be displayed, and the
system will take corresponding actions.
The alarm message will be displayed in the alarm message area of the software
screen, and then recorded in the system log automatically.
The logs will record the time, level, code and detailed information of each warning to
help user record and search errors.
In case of a warning message, check its error code on the Logs screen of the
operating software, and find recommended actions in the Solution field.
9 Troubleshooting 9-1
Figure 9-1 Warning Message Area
Severity: Warning
9-2 9 Troubleshooting
instruction and rerun the tests.
Severity: Pausing
Severity: Forbidding
9 Troubleshooting 9-3
Severity: Shutting down
WARNING:
When troubleshooting the analyzer, first find out whether it is necessary
to switch off the Main Power or Analyzing Unit Power.
BIOHAZARD:
Wear gloves and lab coat and, if necessary, goggles.
9-4 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
C0008 0 Check printer
Printer is not powered connection. Check if
Printer
on. Cable is not printer is powered
cannot be
connected. No driver is on, driver and default
connected
installed printer has been
installed
C0009 0 Check for paper jam.
Printer Paper jam. No paper. Check if printer is
failure No ink busy, and print tasks
are too many
C0010 0 Help No help document. Help Check if help
document document is damaged. document exists or is
error No memory space damaged
C0011 0 No sound card is
Sound card installed. Sound card Reinstall sound card
failure failure. Incorrect sound or sound card driver
card driver
9 Troubleshooting 9-5
9.2.1.3 Calculation
Error Level Error Probable Causes Corrective Actions
Code Message
C0301 0 (%s test) Reagent blank
Replace reagent.
Calibration absorbance is too
Replace calibrator.
sensitivity high. Calibrator is
Recalibrate
error degenerated
C0302 0 (%s test)
Coefficient Calibrator goes Replace reagent.
difference wrong. Reagent goes Replace calibrator.
limit is out of wrong Recalibrate
range
C0303 0 (%s test)
Multi-point or
non-linear
Calibrator goes Replace reagent.
calibration
wrong. Reagent goes Replace calibrator.
correlation
wrong Recalibrate
coefficient
(R2) is out of
range
C0304 0 (%s test)
Calibrator goes Replace reagent.
Reaction
wrong. Reagent goes Replace calibrator.
curve SD is
wrong Recalibrate
out of range
C0305 0 (%s test) Results cannot be
Replace reagent.
Calibration calculated by
Replace calibrator.
parameters specified rule. Results
Recalibrate or
cannot be are abnormal.
recalculate calibration
calculated by Calibration is not
parameters
given method convergent
C0306 0 (%s test) Reagent blank
Replace reagent.
Absorbance absorbance is too
Replace calibrator.
of 0 calibrator high. Calibrator is
Recalibrate
is out of range degenerated
C0307 0 (%s test)
Calibration replicates
Calibration
are unfinished.
data is Fill reagent and
Reagent is
incomplete. calibrator. Recalibrate
insufficient. Calibrator
Cannot
is insufficient
calculate
C0308 0 (%s test
and %d Key points are lost
sample)Resp during response Rerun
onse calculate calculation
error
C0309 0 (%s test Abnormal sample
and %d (hemolysis, etc).
Run diluted sample, or
sample)Resp Calibrator
recalibrate
onse is out of concentration is too
range low
C0310 0 If problem occurs
Communication
Received data frequently, reconnect
between analyzing
check sum serial cable. If problem
unit and operation
error remains, contact the
unit is interfered
developer
9-6 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
C0311 0 Control is
(%s test) degenerated. Rerun. Replace control
Real-time QC Reagent goes wrong. or reagent and rerun.
12s warning Light intensity is Replace light source
abnormal
C0312 0 Control is
(%s test)
degenerated. Rerun. Replace control
Real-time QC
Reagent goes wrong. or reagent and rerun.
of 13s is out
Light intensity is Replace light source
of control
abnormal
C0313 0 Control is
(%s test)
degenerated. Rerun. Replace control
Real-time QC
Reagent goes wrong. or reagent and rerun.
of 22s is out
Light intensity is Replace light source
of control
abnormal
C0314 0 Control is
(%s test)
degenerated. Rerun. Replace control
Real-time QC
Reagent goes wrong. or reagent and rerun.
R4s is out of
Light intensity is Replace light source
control
abnormal
C0315 0 Control is
(%s test)
degenerated. Rerun. Replace control
Real-time QC
Reagent goes wrong. or reagent and rerun.
41s is out of
Light intensity is Replace light source
control
abnormal
C0316 0 Control is
(%s test)
degenerated. Rerun. Replace control
Real-time QC
Reagent goes wrong. or reagent and rerun.
10x is out of
Light intensity is Replace light source
control
abnormal
C0317 0 (%s test)
Calibrator goes
Calibration Replace reagent or
wrong. Reagent goes
repeatability is calibrator. Recalibrate
wrong
out of range
C0318 0 (%s test)
Incorrect reagent
Multi-point or
dispensing volume. Retest un-monotone
nonlinear
Incorrect calibrator points. Recalibrate
calibration is
dispensing volume.
not monotone
C0319 0 (%s)Result Abnormal test result. Rerun participated
cannot be Error occurs like 0 tests. Check and reset
calculated dividend calculation formula
C0320 0 (%d sample
/%s test) Response error.
Concentration Calibration formula Rerun or recalculate
cannot be error
calculated
C0321 0 Rerun, or rerun after
Absorbance is Sample goes wrong.
replacing reagent or
out of range Reagent goes wrong
sample
C0322 0 (%s test
Antigen excess. Too
and %d
much sample.
sample) Dilute and rerun
Sample concentration
Prozone
is too high.
check error
9 Troubleshooting 9-7
Error Level Error Probable Causes Corrective Actions
Code Message
C0323 0 (%s test
and %d
Reagent is stored too Rerun after replacing
sample)R1
long or expired reagent
blank exceeds
limit
C0324 0 (%s test
and %d
sample)No
Rerun, or rerun after
linear interval Unsteady reagent.
replacing reagent or
in Kinetic Sample goes wrong
sample
analysis.
Cannot
calculate
C0325 0 (%s test
and %d Out of sample or Check the
sample) has system has been in corresponding reaction
not performed Sample Stop status. curve of the test for
second time Cannot add more antigen excess. If it
sample sample occurs, rerun the test.
dispensing
9-8 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
repeatedly
C0502 0 Barcode %s
Reagent barcode is
includes Rescan this reagent
printed in wrong
invalid barcode, or reprint and
format. Barcode scan
reagent rescan as configured
error
information
C0503 0 Rescan. Reprint and
Barcode %s Barcode scan error.
rescan barcode as
check error Bar code print error
configured
C0504 0 Reset barcode format,
%s barcode Barcode is in wrong
or reprint or rescan
error format
barcode
C0505 0 %s reagent
Check reagent bottle to
barcode has Barcode already
see if barcode is used
two exists on current
repeatedly. Reprint and
corresponding reagent disk
rescan
positions
9 Troubleshooting 9-9
Error Lev Error Probable Causes Corrective Actions
Code el Message
C0605 0 If problem occurs
accidentally, send or
receive again. If
Field value is Communication
problem occurs
not found failure
frequently, consult
developer of LIS or
equipment
C0606 0 If problem occurs
accidentally, send or
receive again. If
Wrong Communication
problem occurs
message type failure
frequently, consult
developer of LIS or
equipment
C0607 0 If problem occurs
accidentally, send or
receive again. If
Wrong event Communication
problem occurs
No. failure
frequently, consult
developer of LIS or
equipment
C0608 0 If problem occurs
accidentally, send or
receive again. If
Wrong Communication
problem occurs
process ID failure
frequently, consult
developer of LIS or
equipment
C0609 0 If problem occurs
accidentally, send or
receive again. If
Wrong version Communication
problem occurs
No. failure
frequently, consult
developer of LIS or
equipment
C0610 0 If problem occurs
accidentally, send or
Unknown receive again. If
Communication
keyword problem occurs
failure
identity frequently, consult
developer of LIS or
equipment
C0611 0 If problem occurs
accidentally, send or
Keyword receive again. If
Communication
identity problem occurs
failure
already exists frequently, consult
developer of LIS or
equipment
C0612 0 If problem occurs
accidentally, send or
receive again. If
Unknown Communication
problem occurs
error failure
frequently, consult
developer of LIS or
equipment
9-10 9 Troubleshooting
Error Lev Error Probable Causes Corrective Actions
Code el Message
C0613 0 Neglect. If problem
Your query
occurs frequently,
does not exist LIS failure
contact developer of
on LIS
LIS or equipment
C0614 13 Send and receive again
LIS host is
after a moment, or
busy. Cannot LIS failure
reconnect to LIS. Reset
respond
LIS
C0615 0 Check network
connection. If problem
LIS does not start.
LIS response occurs continuously for
Communication
is timed out 3 times, contact
failure
developer of LIS or
equipment
C0616 0 Check if LIS host works
normally. Reset LIS
host. If problem occurs
Application LIS host database
continuously for 3
record locked error
times, contact the LIS
manufacture or
equipment developer
C0617 0 Send and receive after
LIS host does
LIS host failure a while. Reconnect LIS
not respond
host. Reset LIS host
C0618 0 Wrong Test configuration Check again. Set
barcode error in LIS host and corresponding tests
information operating software. relationship between
downloaded Tests missing or extra operating software and
from LIS tests in LIS host LIS host
9.2.1.7 Others
Error Level Error Probable Causes Corrective Actions
Code Message
C0701 2 All reagents in this
kind of bottles do not
Fill reagent of this test,
%s test has reach minimum limit.
or replace it with new
no enough %s All reagents of this
reagent
kind cannot be
detected
C0702 8 Check if equipment is
Analyzing unit is busy
Test period powered on. Restore
and cannot return
timed out. failure. Communicate
result, serial
Cannot with control software.
communication error,
continue Restart analyzing unit
or power failure
and operation unit
C0703 9 Retest dark current on
Utilities-->Daily Maint.
Dark current Excessive circuit
page. Adjust
is too high noise
photoelectric gain.
Contact your developer
C0704 9 Reset the main unit on
Analyzing unit Parameter
Utilities-->Daily Maint.
reset failed downloading failed
page
9 Troubleshooting 9-11
Error Level Error Probable Causes Corrective Actions
Code Message
C0705 8 Restore failure on
Utilities-->Daily Maint.
Analyzing unit
Sensor failure. page. Restart analyzing
failure cannot
Motor/Belt failure unit and operation unit.
recover
Contact equipment
developer
C0706 0 No floppy disk or U
Storage disk is inserted. Check if U disk or
device error. Insufficient disk floppy disk is inserted or
Cannot export space. Floppy disk or full. Check if storage
data U disk is locked or device is damaged
damaged
C0707 0 No floppy disk or U
disk is inserted. File
Storage Check if U disk or
does not exist. File
device error. floppy disk is inserted or
error. File is
Cannot import full. Check if storage
damaged. Floppy
data device is damaged
disk or U disk is
locked or damaged
C0709 0 Insufficient
Insufficient wash Add alkaline wash
wash solution
solution on reagent solution on specified
on reagent
disk position of reagent disk
disk
C0710 2 Insufficient
Add distilled water on
distilled water Insufficient distilled
specified position of
on reagent water on reagent disk
reagent disk
disk
C0711 0 Insufficient
Insufficient acid wash Add acid wash solution
acid wash
solution on sample on specified position of
solution on
disk sample disk
sample disk
C0712 0 Insufficient
Insufficient alkaline Add alkaline wash
alkaline wash
wash solution on solution on specified
solution on
sample disk position of sample disk
sample disk
C0713 3 Insufficient
Add distilled water on
distilled water Insufficient distilled
specified position of
on sample water on sample disk
sample disk
disk
C0714 9 Check if lamp is turned
on, and check the
Lamp aged (service
cuvettes on
time over 2,000
Utilities-->Daily Maint.
Light intensity hours). Lamp is not
Page. If failure remains,
is weak turned on. Lamp is
replace the lamp. If
loose. All cuvettes are
failure still remains,
dirty
contact equipment
developer
9-12 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
C0715 0 Perform cuvette blank
again. If blank limit is
Cuvette is dirty. The
exceeded for 10 times,
amount of water to
Blank of replace the cuvette. If
measure the sixth
cuvette %s problem happens to all
phase water blank is
exceeds limit cuvettes, replace the
not enough. Light
lamp. If problem still
intensity is too weak
remains, contact
equipment developer
C0716 8 Received data is too
Received data Contact equipment
much and exceeds
overflow developer
buffer capacity
9 Troubleshooting 9-13
Error Level Error Probable Causes Corrective Actions
Code Message
C0724 11 Reagent is Replace the reagent
Reagent ran out
exhausted pack with a new one
9-14 9 Troubleshooting
Error Level Error Message Probable Causes Corrective Actions
Code
A0008 8 Switch off analyzing
unit power and switch
on again. Restore
E2PROM read/write failure on
Memory error
error Utilities-->Daily Maint.
page. If this message
appears for 3 times,
contact the developer
A0009 0 Received data in Rerun. If problem
Photoelectric
single period is less occurs frequently,
data is lost
than 90 contact the developer
A0010 8 If optic measurement
assembly goes wrong,
replace AD assembly.
If AD collection board
Photoelectric AD value is too low works normally,
output is (below 1000) or too remove optic
abnormal high (over 65500) measurement
assembly, and check if
preamplification board
and optical path are
normal
A0011 8 Photoelectric data
Photoelectric Restart analyzing unit
buffer is full. Cannot
data overflow and operation unit
process new data
A0012 8 Photoelectric circuit
Photoelectric
does not return result Restart analyzing unit
collection is
via FIFO in specified and operation unit
timed out
time
A0013 8
Restart analyzing unit
Downloading Incompatible or and replace with new
failed wrong version version. If failed again,
contact the developer
9 Troubleshooting 9-15
Error Level Error Message Probable Causes Corrective Actions
Code
A0017 0 Switch off analyzing
unit power and switch
on again. Restore
Communication Instruction failure on
frame error communication error Utilities-->Daily Maint.
page. If this message
appears for 3 times,
contact the developer
A0018 0 Switch off analyzing
unit power and switch
on again. Restore
Instruction failure on
Serial port error
communication error Utilities-->Daily Maint.
page. If this message
appears for 3 times,
contact the developer
9-16 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0105 8 Wrong
Switch off analyzing unit
sensor
power and switch on
status when
again. Restore failure
sample
Vertical position on Utilities-->Daily
probe
sensor failure Maint. page. If this
moves
message appears for 3
vertically(in
times, contact the
reaction
developer
disk)
A0106 5 Sample
probe
cannot find
Vertical position
home Restore failure. If failed
sensor failure.
position for 3 times, contact the
Obstruction exists in
when developer
vertical direction
moving
vertically(oth
er position)
A0107 8 Sample
probe
cannot find
home Vertical position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving vertical direction
vertically(in
reaction
disk)
A0108 15 Sample
probe
bumps when If auto reset fails,
Wrong position.
moving restore failure. Remove
Obstruction exists
vertically obstruction and reset
(other
position)
A0109 15 Sample
probe
If auto reset fails,
bumps when Wrong position.
restore failure. Remove
moving Obstruction exists
obstruction and reset
vertically(IS
E unit)
A0110 15 Sample
probe
bumps when If auto reset fails,
Wrong position.
moving restore failure. Remove
Obstruction exists
vertically(in obstruction and reset
reaction
disk)
A0111 5 Lowering
down at Sample probe is not
If auto reset fails,
current in vertical home
restore failure. If failed
position is position. Current
for 3 times, contact the
not allowed position is not proper
developer
(other for lowering down
position)
9 Troubleshooting 9-17
Error Level Error Probable Causes Corrective Actions
Code Message
A0112 8 Lowering
down at
Sample probe is not
current If auto reset fails,
in vertical home
position is restore failure. If failed
position. Current
not for 3 times, contact the
position is not proper
allowed(in developer
for lowering down
reaction
disk)
A0113 5 Wrong
Switch off analyzing unit
sensor
power and switch on
status when
again. Restore failure
sample
Rotational position on Utilities-->Daily
probe
sensor failure Maint. page. If this
moves
message appears for 3
horizontally
times, contact the
(other
developer
position)
A0114 11 Wrong Switch off analyzing unit
sensor power and switch on
status when again. Restore failure
sample Rotational position on Utilities-->Daily
probe sensor failure Maint. page. If this
moves message appears for 3
horizontally times, contact the
(ISE unit) developer
A0115 8 Wrong
Switch off analyzing unit
sensor
power and switch on
status when
again. Restore failure
sample
Rotational position on Utilities-->Daily
probe
sensor failure Maint. page. If this
moves
message appears for 3
horizontally
times, contact the
(in reaction
developer
disk)
A0116 5 Sample
probe
cannot find
home Rotational position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving horizontal direction
horizontally
(other
position)
A0117 8 Sample
probe
cannot find
home Rotational position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving horizontal direction
horizontally
(in reaction
disk)
9-18 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0118 15 Sample
probe
collides Sample probe is
If auto reset fails,
when obstructed or falls
restore failure. Check
moving when moving
motor and belt
horizontally horizontally.
(other
position)
A0119 8 Sample
probe
collides Sample probe is
If auto reset fails,
when obstructed or falls
restore failure. Check
moving when moving
motor and belt
horizontally horizontally.
(in reaction
disk)
A0120 5 Rotating at Sample probe is not
current in horizontal home If auto reset fails,
height is not position. Current restore failure. If failed
allowed height is not proper for 3 times, contact the
(other for rotation(highest developer
position) position)
A0121 8 Rotating at Sample probe is not
current in horizontal home If auto reset fails,
height is not position. Current restore failure. If failed
allowed(in height is not proper for 3 times, contact the
reaction for rotation(highest developer
disk) position)
A0122 5 If auto reset fails,
Syringe
restore failure. If failed
sensor is in Syringe sensor error
for 3 times, contact the
wrong status
developer
A0123 5 Check if sample syringe
reaches maximum limit
Sample syringe
Syringe and cannot restore.
reaches maximum
cannot find Restore failure, or reset
stroke. Cannot
home after pushing syringe to
restore or dispense
position home position. If failed
sample
for 3 times, contact the
developer
A0125 8 Sample
probe does
not detect
No deionized water Add deionized water
wash
solution
level
A0126 1 Sample
probe does
not detect No R1 dispensed. Check if reagent is
liquid level Insufficient R1 sufficient. Rerun
on reaction
disk
9 Troubleshooting 9-19
Error Level Error Probable Causes Corrective Actions
Code Message
A0127 3 Sample
probe does
No sample tube.
not detect Check if sample is
Sample is already
liquid level sufficient. Rerun
depleted
on sample
disk
A0128 1 Insufficient
sample Insufficient sample Check sample volume
dispensing aspiration volume and rerun
volume
A0129 1 Sample
Sample syringe Restore failure. If failed
syringe
aspirates full for 3 times, contact the
aspirates
abnormally developer
too much
A0130 1 Sample
Sample syringe Restore failure. If failed
syringe
dispenses empty for 3 times, contact the
dispenses
abnormally developer
too much
A0131 1 Sample
Add samples or replace
probe does Insufficient sample.
with standard sample
not aspirate Wrong tube type
tube
sample
A0133 11 Switch off analyzing unit
power and switch on
Execution again. Restore failure
result is not Instruction execution on Utilities-->Daily
received in is timed out Maint. page. If this
given time message appears for 3
times, contact the
developer
A0134 8 Switch off analyzing unit
power and switch on
No again. Restore failure
response, or Instruction execute on Utilities-->Daily
response error Maint. page. If this
error message appears for 3
times, contact the
developer
9-20 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0202 8 Reset analyzing unit
power and restart
operating software.
Instruction Instruction parameter
Then retry this
parameter does not comply with
instruction. If this
error protocol
message appears for 3
times, contact the
developer
A0203 5 Switch off analyzing
unit power and switch
on again. Download
Unit is busy and does parameters and restore
No execute
not reset failure on
condition
mechanically Utilities-->Daily Maint.
page. If this message
appears for 3 times,
contact the developer
A0204 5 Restore failure on
Home Utilities-->Daily Maint.
Cannot find home
position is not page. If this message
position
found appears for 3 times,
contact the developer
A0205 5 Restore failure on
Utilities-->Daily Maint.
Step missed Belt failure page. If this message
appears for 3 times,
contact the developer
A0206 5 Restore failure on
Utilities-->Daily Maint.
Wrong sensor
Sensor failure page. If this message
status
appears for 3 times,
contact the developer
A0207 12 Sample barcode
Bar code
reader is not installed. Reboot the analyzer. If
reader does
Barcode reader is not problem remains,
not work
connected to PCB contact the developer
normally
properly
A0208 0 Check if barcode label
Barcode digit error. is dirty, skewed, or
Bar code
Data format error. No placed correctly.
error
end mark Rescan or scan after
reprinting
A0209 12 Rescan after restoring
Bar code
Scanning too many or failure. If this message
sending
too fast appears for 3 times,
buffer is full
contact the developer
A0210 11 Switch off analyzing
unit power and switch
Execution on again. Restore
result is not Instruction execution failure on
received in is timed out Utilities-->Daily Maint.
given time page. If this message
appears for 3 times,
contact the developer
9 Troubleshooting 9-21
Error Level Error Probable Causes Corrective Actions
Code Message
A0211 11 Switch off analyzing
unit power and switch
on again. Restore
No response,
Instruction execute failure on
or response
error Utilities-->Daily Maint.
error
page. If this message
appears for 3 times,
contact the developer
9-22 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0406 4 Reagent
probe
cannot find
home Vertical position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving vertical direction
vertically
(other
position
A0407 8 Reagent
probe
cannot find
home Vertical position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving vertical direction
vertically(in
reaction
disk)
A0408 15 Reagent
probe
bumps
If auto reset fails,
when Wrong position.
restore failure. Remove
moving Obstruction exists
obstruction and reset
vertically
(other
position)
A0409 15 Reagent
probe
bumps
If auto reset fails,
when Wrong position.
restore failure. Remove
moving Obstruction exists
obstruction and reset
vertically(in
reaction
disk)
A0410 4 Lowering
down at Reagent probe is not
If auto reset fails,
current in vertical home
restore failure. If failed
position is position. Current
for 3 times, contact the
not position is not proper
developer
allowed(oth for lowering down
er position)
A0411 8 Lowering
down at
Reagent probe is not
current If auto reset fails,
in vertical home
position is restore failure. If failed
position. Current
not for 3 times, contact the
position is not proper
allowed(in developer
for lowering down
reaction
disk)
9 Troubleshooting 9-23
Error Level Error Probable Causes Corrective Actions
Code Message
A0412 4 Wrong
Switch off analyzing unit
sensor
power and switch on
status when
again. Restore failure
reagent
Rotational position on Utilities-->Daily
probe
sensor failure Maint. page. If this
moves
message appears for 3
horizontally
times, contact the
(other
developer
position)
A0413 8 Wrong
Switch off analyzing unit
sensor
power and switch on
status when
again. Restore failure
reagent
Rotational position on Utilities-->Daily
probe
sensor failure Maint. page. If this
moves
message appears for 3
horizontally
times, contact the
(in reaction
developer
disk)
A0414 4 Reagent
probe
cannot find
home Rotational position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving horizontal direction
horizontally
(other
position)
A0415 11 Reagent
probe
cannot find
home Rotational position
Restore failure. If failed
position sensor failure.
for 3 times, contact the
when Obstruction exists in
developer
moving horizontal direction
horizontally(
in reaction
disk)
A0416 15 Reagent
probe
collides Reagent probe is
If auto reset fails,
when obstructed or falls
restore failure. Check
moving when moving
motor and belt
horizontally horizontally
(other
position)
A0417 8 Reagent
probe
collides Reagent probe is
If auto reset fails,
when obstructed or falls
restore failure. Check
moving when moving
motor and belt
horizontally( horizontally
in reaction
disk)
9-24 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0418 4 Reagent probe is not
Rotating is in horizontal home If auto reset fails,
not allowed position. Current restore failure. If failed
(other height is not proper for 3 times, contact the
position) for rotation(highest developer
position)
A0419 8 Reagent probe is not
Rotating is
in horizontal home If auto reset fails,
not
position. Current restore failure. If failed
allowed(in
height is not proper for 3 times, contact the
reaction
for rotation(highest developer
disk)
position)
A0420 4 Syringe If auto reset fails,
sensor is in restore failure. If failed
Syringe sensor error
wrong for 3 times, contact the
status developer
A0421 4 Check if reagent syringe
reaches maximum limit
Reagent syringe and cannot restore.
Syringe
reaches maximum Restore failure, or reset
cannot find
stroke. Cannot after pushing syringe to
home
restore or dispense home position. If this
position
reagent problem occurs for 3
times, contact the
developer
A0422 8 Reagent
probe does
not detect
No deionized water Add deionized water
wash
solution
level
A0423 1 Reagent
No R1 or sample or
probe does
insufficient R1 in
not detect Check if reagent is
reaction cuvette when
liquid level sufficient. Rerun
system dispenses
on reaction
R2.
disk
A0424 2 Reagent
probe does
No reagent on R2
not detect Check if reagent is
position. Reagent is
liquid level sufficient. Rerun
depleted
on reagent
disk
A0425 1 Insufficient
reagent Insufficient reagent Check reagent volume
dispensing aspiration volume and rerun
volume
A0426 1 Reagent
Reagent syringe Restore failure. If failed
syringe
aspirates full for 3 times, contact the
aspirates
abnormally developer
too much
A0427 1 Reagent
Reagent syringe Restore failure. If failed
syringe
dispenses empty for 3 times, contact the
dispenses
abnormally developer
too much
9 Troubleshooting 9-25
Error Level Error Probable Causes Corrective Actions
Code Message
A0428 8 Switch off analyzing unit
power and switch on
Execution again. Restore failure
result is not Instruction execution on Utilities-->Daily
received in is timed out Maint. page. If this
given time message appears for 3
times, contact the
developer
A0429 8 Switch off analyzing unit
power and switch on
No again. Restore failure
response, Instruction execute on Utilities-->Daily
or response error Maint. page. If this
error message appears for 3
times, contact the
developer
9-26 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A0506 4 Restore failure. If this
Wrong
message appears for 3
sensor Sensor failure
times, contact the
status
developer
A0507 13 Reagent barcode
Bar code
reader is not installed. Reboot the analyzer. If
reader does
Barcode reader is not problem remains,
not work
connected to PCB contact the developer
normally
properly
A0508 0 Check if barcode label
Barcode digit error. is dirty, skewed, or
Bar code
Data format error. No placed correctly.
error
end mark Rescan or scan after
reprinting
A0509 13 Rescan after resetting
Bar code mechanically. If this
Scanning too many or
sending message appears for 3
too fast
buffer is full times, contact the
developer
A05010 8 Switch off analyzing unit
power and switch on
Execution again. Restore failure
result is not Instruction execution on Utilities-->Daily
received in is timed out Maint. page. If this
given time message appears for 3
times, contact the
developer
A05011 8 Switch off analyzing unit
power and switch on
No again. Restore failure
response, Instruction execute on Utilities-->Daily
or response error Maint. page. If this
error message appears for 3
times, contact the
developer
9 Troubleshooting 9-27
A0602 8 Reset analyzing unit
power and restart
operating software.
Instruction Instruction parameter
Then retry this
parameter does not comply with
instruction. If this
error protocol
message appears for 3
times, contact the
developer
A0603 8 Switch off analyzing
unit power and switch
on again. Download
Unit is busy and does parameters and restore
No execute
not reset failure on
condition
mechanically Utilities-->Daily Maint.
page. If this message
appears for 3 times,
contact the developer
A0604 8 Reaction Reaction disk home Restore failure. If this
disk cannot position sensor message appears for 3
find home failure. Coder goes times, contact the
position wrong developer
A0605 8 Reaction
Restore failure. If this
disk missed
Motor failure. Belt message appears for 3
step when
failure times, contact the
moving
developer
horizontally
A0606 8 Reaction Restore failure. If this
disk sensor message appears for 3
Sensor failure
is in wrong times, contact the
status developer
A0608 9 No cuvette on a Load the cuvette or
Light signal specified position or contact the developer
too strong photoelectric gain and adjust
adjusting error photoelectric gain
A0609 9 Switch off analyzing
unit power and switch
Photoelectric Photoelectric buffer
on again. If this
buffer is overflow, or FIFO
message appears for 3
abnormal overflow
times, contact the
developer
A0610 1 After testing, switch off
analyzing unit power
Photoelectric
Photoelectric and switch on again. If
collection and
data error this message appears
conversion failed
for 3 times, contact the
developer
A0611 8 Switch off analyzing
unit power and switch
Execution on again. Restore
result is not Instruction execution failure on
received in is timed out Utilities-->Daily Maint.
given time page. If this message
appears for 3 times,
contact the developer
9-28 9 Troubleshooting
A0612 8 Switch off analyzing
unit power and switch
No on again. Restore
response, or Instruction execute failure on
response error Utilities-->Daily Maint.
error page. If this message
appears for 3 times,
contact the developer
9 Troubleshooting 9-29
Error Level Error Message Probable Causes Corrective Actions
Code
A0806 6 Mixer cannot find
Vertical position Restore failure. If
home position
sensor failure. failed for 3 times,
when moving
Obstruction exists contact the
vertically(other
in vertical direction developer
position)
A0807 8 Mixer cannot find
Vertical position Restore failure. If
home position
sensor failure. failed for 3 times,
when moving
Obstruction exists contact the
vertically(in
in vertical direction developer
reaction disk)
A0808 6 Mixer is not in
Lowering down If auto reset fails,
vertical home
at current restore failure. If
position. Current
position is not failed for 3 times,
position is not
allowed(other contact the
proper for lowering
position) developer
down
A0809 8 Mixer is not in
Lowering down If auto reset fails,
vertical home
at current restore failure. If
position. Current
position is not failed for 3 times,
position is not
allowed(in contact the
proper for lowering
reaction disk) developer
down
A0810 6 Switch off analyzing
unit power and
Wrong sensor switch on again.
status when Restore failure on
Rotational position
mixer moves Utilities-->Daily
sensor failure
horizontally(other Maint. page. If this
position) message appears
for 3 times, contact
the developer
A0811 8 Switch off analyzing
unit power and
Wrong sensor switch on again.
status when Restore failure on
Rotational position
mixer moves Utilities-->Daily
sensor failure
horizontally(in Maint. page. If this
reaction disk) message appears
for 3 times, contact
the developer
A0812 6 Mixer cannot find Rotational position
Restore failure. If
home position sensor failure.
failed for 3 times,
when moving Obstruction exists
contact the
horizontally(other in horizontal
developer
position) direction
A0813 8 Mixer cannot find Rotational position
Restore failure. If
home position sensor failure.
failed for 3 times,
when moving Obstruction exists
contact the
horizontally(in in horizontal
developer
reaction disk) direction
A0814 6 Mixer is not in
If auto reset fails,
Rotating at horizontal home
restore failure. If
current height is position. Current
failed for 3 times,
not allowed(other height is not proper
contact the
position) for rotation(highest
developer
position)
9-30 9 Troubleshooting
Error Level Error Message Probable Causes Corrective Actions
Code
A0815 8 Mixer is not in
If auto reset fails,
Rotating at horizontal home
restore failure. If
current height is position. Current
failed for 3 times,
not allowed(in height is not proper
contact the
reaction disk) for rotation(highest
developer
position)
A0816 8 Switch off analyzing
unit power and
switch on again.
Execution result Instruction Restore failure on
is not received in execution is timed Utilities-->Daily
given time out Maint. page. If this
message appears
for 3 times, contact
the developer
A0817 6 Switch off analyzing
unit power and
switch on again.
Restore failure on
No response, or Instruction execute
Utilities-->Daily
response error error
Maint. page. If this
message appears
for 3 times, contact
the developer
9 Troubleshooting 9-31
Error Code Level Error Message Probable Corrective
Causes Actions
A0903 0 Reset analyzing
unit power and
restart
Unit is busy. operating
Instruction software. Then
No execute
conflicts. retry this
condition
Instruction buffer instruction. If
is full this message
appears for 3
times, contact
the developer
9-32 9 Troubleshooting
Error Code Level Error Message Probable Corrective
Causes Actions
A0907 0 Reset analyzing
unit power and
restart
operating
Wash solution Preheat
software. If this
temperature is temperature
message
fluctuated collection error
appears
repeatedly,
contact the
developer
9 Troubleshooting 9-33
Error Code Level Error Message Probable Corrective
Causes Actions
A0910 0 Reset analyzing
unit power and
restart
Reaction disk
Reaction disk operating
temperature
temperature is software. If this
collection error.
not steady in message
Heater control
specified time appears
error
repeatedly,
contact the
developer
A0912 0 Contact
Refrigerator fans Fan circuit failed.
instrument
are abnormal Fan is damaged
developer
9-34 9 Troubleshooting
Error Code Level Error Message Probable Corrective
Causes Actions
A0914 8 Switch off
analyzing
unit power
and
switch on
again.
Restore
No response, or Instruction failure. If
response error execute error this
message
appears
for 3
times,
contact
the
developer
A0924 0 DI water
DI water
temperature Contact
temperature
sensor is instrument
sensor is not
disconnected or developer
connected
damaged
A0925 0 Environment
Environment
temperature Contact
temperature
sensor is instrument
sensor is not
disconnected or developer
connected
damaged
9 Troubleshooting 9-35
Error Level Error Probable Causes Corrective Actions
Code Message
9-36 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
9 Troubleshooting 9-37
9.2.2.10 ISE Unit
Error Level Error Probable Causes Corrective Actions
Code Message
A1101 11 ISE unit Reconnect. Reset ISE
ISE unit connection
handshake is unit. Power on ISE unit
error
abnormal again
A1102 11 Wait a moment, and
ISE unit is ISE unit is executing
re-execute ISE
busy other instruction
instruction
A1103 11 Power switched off.
Communication Reconnect to power.
failed. Serial cable Reconnect serial cable.
ISE unit does damaged or Perform ISE
not respond unconnected. Module initialization. Contact the
connector damaged. developer to replace
Board elements board
damaged
A1104 11 Reinstall sensor.
Replace calibrant B and
Electrode installation
rerun, if still low, replace
incorrect. Calibrator
calibrant A and rerun.
expired. Electrode
Na+ Replace failed sensor
degenerated. Bubbles
electrode and rerun. Reinstall
in reference
slope is out of electrode, eliminate
electrode. Reference
standard bubbles and calibrate.
electrode damaged.
range Replace reference or
Electrodes interfered.
Na+ electrode and rerun.
Module or tubing
Monitor temperature, if
temperature above 37
too high, relocate
equipment
A1105 11 Reinstall sensor.
Replace calibrant B and
Electrode installation
rerun, if still low, replace
incorrect. Calibrator
calibrant A and rerun.
expired. Electrode
Replace failed sensor
K+ electrode degenerated. Bubbles
and rerun. Reinstall
slope is out of in reference
electrode, eliminate
standard electrode. Reference
bubbles and calibrate.
range electrode damaged.
Replace reference or K+
Electrodes interfered.
electrode and rerun.
Module or tubing
Monitor temperature, if
temperature above 37
too high, relocate
equipment
A1106 11 Reinstall sensor.
Electrode installation Replace calibrant B and
incorrect. Calibrator rerun, if still low, replace
expired. Electrode calibrant A and rerun.
Cl- electrode degenerated. Bubbles Replace failed sensor
slope is out of in reference and rerun. Reinstall
standard electrode. Reference electrode, eliminate
range electrode damaged. bubbles and calibrate.
Electrodes interfered. Replace reference or Cl-
Module or tubing electrode and rerun.
temperature above 37 Monitor temperature, if
too high, relocate
9-38 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
equipment
A1108 11 Replace electrode and
Na+ Electrode rerun. Check for
electrode degenerated. Noise electrical noise. If board
noise error spike interference element is damaged,
replace the board
A1109 11 Replace electrode and
Electrode rerun. Check for
K+ electrode
degenerated. Noise electrical noise. If board
noise error
spike interference element is damaged,
replace the board
A1110 11 Replace electrode and
Electrode rerun. Check for
Cl- electrode
degenerated. Noise electrical noise. If board
noise error
spike interference element is damaged,
replace the board
A1112 11 Replace reference
Reference electrode electrode and rerun.
Na+, K+, Cl- degenerated. Check for electrical
electrodes Environment noise. Check unit
noise error interfered by electrical grounding. If board
noise spike element is damaged,
replace the board
A1113 11 Replace failed electrode
and run. Check calibrant
Electrode
A channel and
Na+ degenerated. New
recalibrate. In case of
electrode drift electrode or new
new electrode, drift may
calibrant A is used
occur, wait for 15
minutes and test again
A1114 11 Replace failed electrode
and run. Check calibrant
Electrode
A channel and
K+ electrode degenerated. New
recalibrate. In case of
drift electrode or new
new electrode, drift may
calibrant A is used
occur, wait for 15
minutes and test again
A1115 11 Replace failed electrode
and run. Check calibrant
Electrode
A channel and
Cl- electrode degenerated. New
recalibrate. In case of
drift electrode or new
new electrode, drift may
calibrant A is used
occur, wait for 15
minutes and test again
A1117 11 Replace reference
Reference electrode
electrode and rerun.
degenerated.
Na+, K+, Cl- Check for electrical
Environmental electric
electrodes noise. If board element
pulse. New electrode
drift is damaged, replace the
or new calibrant A is
board. Check calibrant A
used
channel and recalibrate
9 Troubleshooting 9-39
Error Level Error Probable Causes Corrective Actions
Code Message
A1118 11 Replace failed electrode
and run. Check calibrant
Na+ Electrode
A channel and
electrode degenerated. New
recalibrate. In case of
voltage electrode or new
new electrode, drift may
overflow calibrant A is used
occur, wait for 15
minutes and test again
A1119 11 Replace failed electrode
and run. Check calibrant
Electrode
K+ electrode A channel and
degenerated. New
voltage recalibrate. In case of
electrode or new
overflow new electrode, drift may
calibrant A is used
occur, wait for 15
minutes and test again
A1120 11 Replace failed electrode
and run. Check calibrant
Electrode
Cl- electrode A channel and
degenerated. New
voltage recalibrate. In case of
electrode or new
overflow new electrode, drift may
calibrant A is used
occur, wait for 15
minutes and test again
A1122 11 Replace reference
Reference electrode electrode and rerun.
Na+, K+, Cl- degenerated. Check for electrical
electrodes Environmental electric noise. If board element
voltage pulse. New electrode is damaged, replace the
overflow or new calibrant A is board. Check calibrator
used A channel and
recalibrate
A1123 3 If sample is less than
Insufficient sample.
70l, increase sample
Sample not aspirated
volume. Fill sufficient
to measurement
Air in sample sample in tube. In case
chamber. Tubing
of wrong electrode
aged. Pump tubing
installation, install again.
clogged or too long
Replace the tubing
A1124 11 Check spring/sealing
ring. Ensure all
electrodes/O rings are
Calibrant A depleted.
correct. Launch a wash
Tubing unconnected.
procedure. Disassemble
Calibrant A pump
the unit and reinstall
failure. Tubing
sensor. Replace bubble
Air in clogged/cracked/bent.
detector, waste pump, or
calibrant A Fibrin and salt in
calibrant A and
electrode tubing.
recalibrate.
Bubble detector
Reconnect/replace
failure. Waste pump
tubing. Check electrical
failure
connection. Replace
pump housing, motor, or
tubing
9-40 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A1125 11 In case of wrong
electrode installation,
check spring and sealing
ring. Ensure all
Air in calibrant B.
electrodes and O rings
Fibrin and salt in
are installed correctly.
Air in electrode tubing.
Press Clean on water
calibrant B Bubble detector
treatment system to
failure. Waste pump
wash. Disassemble this
failure
unit and wash and
reinstall sensor. Replace
bubble detector. Replace
waste pump.
A1126 11 In case of wrong
electrode installation,
check spring and sealing
ring. Ensure all
Air in calibrant B and
electrodes and O rings
A. Fibrin and salt in
are installed correctly.
electrode tubing.
Air in cleaner Press Clean on water
Bubble detector
treatment system to
failure. Waste pump
wash. Disassemble this
failure
unit and wash and
reinstall sensor. Replace
bubble detector. Replace
waste pump.
A1127 11 Calibrator A/B Replace reagent
No fluid in
depleted. No sample package. Check the
tubing
or cleaning solution tubing
A1128 11 Instruction format
Instruction Please contact the
error, or parameter
execute error developer
error
A1129 11 Calibrations ISE unit cannot store
Recalibrate
saving error calibration results
A1130 11 Bubble
Bubble detector is Replace the bubble
detector
damaged detector
failure
A1131 11
Calibrate repeatedly. If
Electrode slope is out problem remains,
Calibration
of range during reinstall failed electrode.
failed
calibration If problem still remains,
replace the electrode
9 Troubleshooting 9-41
Error Level Error Probable Causes Corrective Actions
Code Message
A1132 11 If maintaining, send
instruction again, if
Instruction format
testing, rerun. Otherwise
Instruction error. Parameter
restart operation unit and
execute error error. No execute
analyzing unit. If this
condition
problem remains,
contact the developer
9-42 9 Troubleshooting
Error Level Error Probable Causes Corrective Actions
Code Message
A1137 0 Reinstall sensor.
Electrode installation
Replace calibrant B and
incorrect. Calibrator
rerun, if still low, replace
expired. Electrode
calibrant A and rerun.
degenerated. Bubbles
Samples for Replace failed sensor
in reference
Cl- electrode and rerun. Reinstall
electrode. Reference
are out of electrode, eliminate
electrode goes wrong.
measurement bubbles and calibrate.
Electrodes interfered.
range Replace reference or Cl-
Module or tubing
electrode and rerun.
temperature above
Monitor temperature, if
37. Sample goes
too high, relocate
wrong
equipment
A1139 11 Reagent pack is not
Reagent Check the reagent pack
installed, or reagent
module does installation, or replace it
pack is not connected
not exist with a new one
correctly
9.2.2.11 Others
Error Level Error Probable Causes Corrective Actions
Code Message
9 Troubleshooting 9-43
For Your Notes
9-44 9 Troubleshooting
10 Calculation Methods
Endpoint
Fixed-time
Kinetic
10.1.1 Endpoint
The endpoint or, more correctly, equilibrium method, is the most ideal. The reaction
reaches equilibrium after a period of time. Because the equilibrium constant is very
large, it can be considered that all substrates (analytes) have changed into
products, and absorbance of the reactant does not change any more. The
absorbance change is directly proportional to the analytes concentration.
As shown in Figure 10-1, R1 is the time when reagent is added and is the time
when the sample is added. From L to M the reaction reaches equilibrium and the
absorbance reading is taken. The reagent blank is tested during N and P.
VR1
k1 =
If P12, then VR1 + VS ; if N>12, then k1=1; if N=P=0, then k1=0.
Reagent blank absorbance can be subtracted from the reaction absorbance but
sample blank cannot. To correct the response with sample blank, you should
request sample blank separately, whose response is Rsb = Ai k1 Ab . The
response after being corrected by sample blank is R
'
= R RSb .
10.1.1.2 Double-reagent
Figure 10-2 Double-reagent Endpoint Reaction Curve
As shown in Figure 10-2, R1is the time when the first reagent is added, S is the
time when the sample is added, and R2 is the time when the second reagent is
added. From L to M the reaction reaches equilibrium and the absorbance reading is
taken. The sample blank is tested during N and P.
R = Ai k2 Ab
VR1 + VS
If P42, then k2 = ; if N>42, then k2=1; if N=P=0, then k2=0.
VR1 + VS + VR 2
VR1 + VS
Where, K2Ab is sample blank correction value. k2 = is a volume
VR1 + VS + VR 2
correction factor for double-reagent analysis. VR1, VS and VR2 are volumes of first
reagent, sample and second reagent.
For any first order reaction, the substrate concentration [S] at a given time after the
start of the reaction is given by the following:
[S ] = [S 0 ] e kt
Where,
[ S ]
[ S 0] = kt1 kt 2
e e
That is, within a fixed time interval, the change in substrate concentration is directly
proportional to its initial concentration. This is the general property of first-order
reactions. Within this interval, absorbance change is directly proportional to the
analytes concentration.
10.1.2.1 Single-reagent
Figure 10-3 Single-reagent Fixed-time Reaction Curve
As shown in Figure 10-3, R1 is the time when first reagent is dispensed and S
when sample is dispensed. The absorbance readings are respectively taken at L
and M.
10.1.2.2 Double-reagent
Figure 10-4 Double-reagent Fixed-time Reaction Curve
As shown in Figure 10-4, R1, S and R2 are the time when first reagent, sample and
second reagent are respectively dispensed. The absorbance readings are
respectively taken at L and M. The reagent blank is tested at N and P.
VR1 + VS
Where, k2 = is a volume correction factor for double-reagent
VR1 + VS + VR 2
analysis. VR1, VS and VR2 are volumes of first reagent, sample and second
reagent.
In fact, it is impossible for the substrate concentration to be high enough, and the
reaction will be no longer a zero-order reaction when the substrate is consumed to
a certain degree. Therefore, the theory only stands within certain period. In addition,
the reaction can become steady only after a certain period of time, because the
reaction is complicated at the beginning and there are miscellaneous reactions due
to complex serum compositions.
You should determine the linearity range within the reaction time other than the
reagent blank period.
Figure 10-6 shows the linearity range determination process for increased reaction.
In decreased reaction, the in Figure 10-6 should be changed into .
As shown in Figure 10-8, R1 is the time when first reagent is dispensed and S
when sample is dispensed. The absorbance readings are taken during L and M.
is the absorbance change rate per minute (slope of reaction curve) during L
and M and calculated by the least squares method.
Double-reagent
As shown in Figure 10-9, R1, S and R2 are the time when first reagent, sample and
second reagent are respectively dispensed. The absorbance readings are taken
during L and M. The reagent blank is tested during N and P.
A f Ab
Linearity= 100 < Linearity Limit
Au ,v
or Au ,v 0.006A/minute,
During the high-activity enzyme test, the substrate may be depleted quickly and the
reaction curve will appear obviously nonlinear (a smooth curve). If measurement is
performed by the ordinary procedure, the No linear interval alarm will be triggered,
reminding user to rerun the test after diluting the sample. This will more or less
bring troubles to user.
The system provides the enzyme linearity range extension function, which is
introduced as follows:
When the number of measuring points (N) within the main read time is less than 2,
the enzyme linearity range extension can be implemented.
The maximum reaction rate (Amax) is calculated based on all measuring points
which include that within the lag time and then considered as the response of the
sample. If less than 2 measuring points during the lag time experience substrate
depletion, no result will be calculated and ENC (No calculation interval) is flagged.
If the reaction start time is t1, reaction time is tL-tM, then t1-tL is the lag time. If the
valid measuring points(N<2) within tL-tM are too few to calculate the response, the
reaction rate can be calculated based on all measuring points during t1-tM using
the formula: A (Ai 1-Ai)/(ti 1 ti). (i1, 2M)The maximum A, namely
Amax, is taken as the response of the sample. Therefore, the enzyme linearity
range is extended via the lag time.
The reaction rate method is based on the specified time, in which antibody excess
reaction can reach equilibrium (Figure 10-12) but antigen excess reaction cannot
(Figure 10-13). Prozone check is performed using the following parameters:
(1) End point absorbance A is less than absorbance low limit in increased
reaction or greater than that in decreased reaction;
(2) Absolute value of response R is greater than RCMAX (absolute value of
response of most-concentrated calibrator).