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New Era University

College of Nursing

DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
Competitively inhibits INDICATIONS GI: constipation, There will be an Assess stomach pain,
RANITIDINE ZANTAC gastric acid secretion by Management of peptic diarrhea, evidence of noting characteristics,
HYDROCHLORIDE blocking the effect of ulcer disease, GERD, abdominal pain duodenal ulcer frequency of
histamine on histamine persistent dyspepsia, occurrence, triggers,
healing
h2 receptors. Both & patients at risk of things that
daytime and nocturnal CNS: headache, alter/relieve
acid aspiration during dizziness, malaise, Decrease in the
basal gastric acid
secretions, as well as
general anesth or insomnia, vertigo, abdominal pain/ Note H. pylori, UGI, or
food- and pengastrin- childbirth. confusion, anxiety, discomfort endoscopy findings
stimulated gastric acid CONTRAINDICATION
hallucinations
are inhibited. Weak Cirrhosis of the liver,
inhibitor of cytochrome impaired renal or
hepatic function CV: bradycardia or
P-450 (drug
metabolizing enzymes); tachycardia
thus, drug interactions
involving inhibitions HEMATOLOGIC:
involving inhibition of thrombocytopenia,
hepatic metabolism are granulocytopenia,
not expected to occur leukopenia,
pancytopenia
New Era University
College of Nursing

DRUG STUDY

DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
ENALAPRIL Enalapril (and its active INDICATIONS CV: palpitations, There will be a Record ECG, VS and
MALEATE VASOTEC metabolite enalaprilat) Treatment of essential hypotensions, decrease in BP weight
inhibit angiotensin- & renovascular HTN, chest pain, angina, and decrease in
converting enzyme CHF & prevention of Monitor CBC,
CVA, MI, cardiac preload and
resulting in decreased coronary ischemic electrolytes, renal and
plasma angiotensin II, arrest afterload with LFTs. Reduce dose
events in patients w/ CHF
which leads to with impaired renal
decreased vasopressor
left ventricular GI: diarrhea, function
activity and decreased dysfunction. abdominal pain,
aldosterone secretion. alterations in
The parenteral product CONTRAINDICATION
taste, anorexia,
is enalaprilat injection S
dry mouth,
Angioedema,
constipation,
hereditary or
idiopathic. dyspepsia
Hyperkalemia, renal
artery stenosis, RESPIRATORY:
bilateral or in a bronchitis, cough,
solitary kidney or dyspnea,
renal transplant, renal bronchospasm,
function impairment. URI, pneumonia,
asthma

HEMATOLOGIC:
hrmolytic anemia,
neutropenia,
thrombocytopenia,
bone marrow
depressions

New Era University


College of Nursing

DRUG STUDY
DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
CITICOLINE Citicoline is a complex INDICATIONS Stomach pain, To minimize the Somazine must not
organic molecule that Cerebrovascular diarrhea; attack of sroke be
functions as an disorders including hypotension, administered along
CHOLINER intermediate in the ischemic stroke, tachycardia, with
V biosynthesis of cell parkinsonism & head bradycardia. medicaments
membrane injury. containing
phospholipids. It is CONTRAINDICATIONS meclophenoxate
also known as CDP- Parasympathetic
choline or cytidine hypertonia.
diphosphate choline
(cytidine 5'-
diphosphocholine).
CDP-choline belongs
to the group of
biomolecules in living
systems known as
nucleotides that play
important roles in
cellular metabolism.

New Era University


College of Nursing

DRUG STUDY
DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
CEFUROXIME Cefuroxime axetil is INDICATIONS GI disturbances, There will be a Note for reasons for
AXET absorbed from the GIT Infections of the bone pseudomembrano resolution on the therapy,
and is rapidly & joint, upper & lower us colitis, S&S of infection characteristics of S&S,
hydrolyzed in the resp tract, skin & soft culture results,
headache,
intestinal mucosa and tissue; surgical baseline assessment
blood to cefuroxime. eosinophilic &
infections, UTI, transient increase
Absorption is enhanced
in the presence of food.
gonorrhea. in hepatic
CONTRAINDICATIONS
Peak plasma enzymes, false
concentrations are Hypersensitivity to
+ve Coomb's test.
reported about 2-3 hrs cephalosporins.
after an oral dose. It is
widely distributed in the
body including pleural
fluid, sputum, synovial
fluid and aqueous
humor, but only
achieves therapeutic
concentrations in the
CSF when the meninges
are inflamed. It crosses
the placenta and has
been detected in breast
milk. It is excreted
unchanged by
glomerular filtration and
renal tubular secretion
and high concentrations
are achieved in the
urine.

New Era University


College of Nursing

DRUG STUDY

DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
CEFTRIAXONE Ceftriaxone exerts in vitro INDICATIONS Systemic Resolution of Note for reasons for
ROCEPHIN activity against a wide range Sepsis, meningitis; Adverse Effects: S&S of infection therapy,
of gram-negative and gram- abdominal, biliary tract, characteristics of S&S,
GI Complaints culture results,
positive microorganisms. It GIT, bone, joints, soft There will be a
(about 2% of baseline assessment
is highly stable to most - tissue, renal, resp tract, negative report
ENT, genital & skin & cases): Loose
lactamases, both on culture Assess for GI disease.
penicillinases and wound infections. UTI, stools or
sensitivity test Report any bleeding/
cephalosporinases, of gram- gonorrhea. Periop diarrhea, nausea, bruising, diarrhea.
positive and gram-negative prophylaxis of infections. vomiting,
bacteria CONTRAINDICATIONS
stomatitis and
hypersensitivity to
cephalosporins. glossitis.
Long-acting, broad-
Hematological
spectrum cephalosporin
antibiotic Changes (about
2%):
Eosinophilia,
leukopenia,
granulocytopenia
, hemolytic
anemia and
thrombocytopeni
a.
Skin Reactions
(about 1%):
Exanthema,
allergic
dermatitis,
pruritus,
urticaria, edema
and erythema
multiforme.

New Era University


College of Nursing

DRUG STUDY
DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
SIMVASTATIN Treatment of INDICATIONS Constipation, Note reasons for
REDUSCOL hypercholesterolemia Treatment of diarrhea, therapy,
E (heterozygous familial hypercholesterolemia flatulence, characteristics of S&S,
& nonfamilial) & (heterozygous familial culture results.
heartburn,
mixed dyslipidemia & nonfamilial) & stomach pain, Assess for GI
(type IIa & IIb mixed dyslipidemia dizziness, disorders
hyperlipoproteinemia). (type IIa & IIb headache, nausea,
hyperlipoproteinemia). skin rash. Rarely, Report for any
CONTRAINDICATIONS bleeding/bruising
myalgia, myositis
Active hepatic
or rhabdomyolysis.
disease.

New Era University


College of Nursing

DRUG STUDY
DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
Omeprazole INDICATIONS Headache, Promotion of List reasons for
PEPTISOLV suppresses gastric Treatment of abdominal pain, ulcer healing therapy, frequency
OMEPRAZOLE acid secretion by heartburn & other diarrhea N&V, and characteristics of
specific inhibition of symptoms associated S&S
URTI, rash Relief of pain
the enzyme system w/ GERD. Erosive
Record abdominal
hydrogen/potassium esophagitis, gastric CNS: anxiety Lower gastric assessments,
adenosine hypersecretory disorders, vertigo, acid production radiographic/endosco
triphosphatase (H+/K+ condition, Zollinger- insomnia, pic findings
ATPase) present on Ellison syndrome, nervousness
the secretory surface systemic Monitor CBC
of the gastric parietal mastocytosis, multiple
HEPATIC: overt
cell. endocrine adenoma &
liver disease
peptic ulcer.
CONTRAINDICATIONS cholestatic
Chronic hepatic
disease. CV: angina,
tachycardia,
bradycardia,
palpitation,
peripheral edema,
elevated BP

New Era University


College of Nursing

DRUG STUDY
DRUG ORDER
TRADE / ADVERSE DESIRED NURSING
(Generic name, PHARMACOLOGIC INDICATIONS AND
BRAND EFFECTS OF THE ACTION ON RESPONSIBILITIES/
dosage, route, ACTION OF DRUG CONTRAINDICATIONS
NAME DRUG YOUR CLIENT PRECAUTIONS
frequency, etc.)
ASPIRIN ASPILET Aspirin is an analgesic, INDICATIONS Fever, There will be a For pain, rate and
anti-inflammatory and Aspilet Suspected acute hypothermia, relief of determine the type,
antipyretic. It inhibits MI; Aspilet/EC thirst. pain/discomfort location, and pattern
cyclooxygenase, which Prophylactic treatment of pain, if unusual, or
Dysrythmias, to the patient
is responsible for the of thromboembolic if recurring
synthesis of disorders, MI, transient hypotension,
prostaglandin and ischemic attacks & tachycardia. There will be a Determine history of
thromboxane. It also stroke. For the Agitation, cerebral decrease fever peptic ulcers or
inhibits platelet secondary prevention of edema, coma, and vascular bleeding tedency
aggregation. CV disease in DM confusion, mortality
patients esp those w/ dizziness,
history of MI, vascular
headache,
bypass procedure,
stroke or transient subdural or
ischemic attack & intracranial
angina & those w/ hemorrhage,
additional risk factors: lethargy, seizures.
HTN, smoking, Dehydration,
dyslipidemia & family hyperkalemia,
history of CV disease.
metabolic acidosis,
Revascularization
procedures. Pregnancy- resp alkalosis,
induced HTN. dyspepsia, GI
CONTRAINDICATIONS bleeding,
Asthma, rhinitis & nasal ulceration &
polyps. History of active perforation,
peptic ulcer disease. nausea, vomiting,
Hypersensitivity.
transient hepatic
enzyme
elevations,
hepatitis.

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