Paige Dickins
Britney Ouderkirk
Mr. Gross
English 12 B (3)
14 May 2017
Antibiotic Resistance
Each year in the United States, at least 2 million people become infected with bacteria
that are resistant to antibiotics and at least 23,000 people die each year as a direct result of these
they are absolutely necessary. Antibiotic resistance occurs when an antibiotic has lost its ability
to effectively control or kill bacterial growth; in other words, the bacteria are "resistant" and
What). It is a progressively growing issue in not only the United States, but also in other
countries around the world impacting people of all ages. It leads to longer hospital stays, higher
medical costs, and increased mortality. Antibiotic resistance is one of the biggest threats to
Antibiotic resistance is rising to dangerously high levels in all parts of the world,
impacting people of all ages. New resistance mechanisms are emerging and spreading globally,
threatening our ability to treat common infectious diseases. A growing list of infections such as
pneumonia, tuberculosis, blood poisoning and gonorrhoea are becoming harder, and sometimes
impossible, to treat as antibiotics become less effective (Antibiotic Resistance). The World
Health Organizations
(WHO) first global report on antibiotic resistance reveals serious, worldwide threat to public
health with data from 114 countries (Antibiotic Resistance). Without urgent, coordinated action
by many stakeholders, the world is headed for a post-antibiotic era, in which common infections
and minor injuries which have been treatable for decades can once again kill, says Dr Keiji
antibiotics continue to be used when not necessary, we may not have the privilege of being able
to get rid of sickness quick and easy when they truly are needed which is why it is so important
Antibiotic resistance leads to longer hospital stays, higher medical costs, and increased
mortality. The Institute of Medicine estimates the annual cost of infections caused by antibiotic-
infections (HAIs) are caused by resistant strains. The trends of increasing resistance are most
critical in intensive care unit (ICU) patients, a population extremely susceptible to HAIs which is
what leads to the lengthy hospital stays and the higher medical costs. HAIs caused by
hospital costs and increased length of stay compared to those caused by their susceptible
counterparts. In the United States, approximately 2 million people per year acquire a bacterial
infection while they are in the hospital. Of these, 50 to 70% are caused by antimicrobial-resistant
Antibiotic resistance is one of the biggest threats to global health, food security, and
development today. Increasingly, bacteria and other microorganisms are developing resistance to
the antibiotics used to kill them, both imperiling health and adding to health care costs as doctors
try different medicines, according to a news release. Studies show antibiotic resistance adds as
much as $20 billion per year in excess direct healthcare costs (Coutre). The Centers for Disease
Control and Prevention (CDC) has classified a number of bacteria as presenting urgent, serious,
and concerning threats, many of which are already responsible for placing a substantial clinical
and financial burden on the U.S. health care system, patients, and their families (Ventola).
Antibiotics are called "societal drugs," since antibiotic resistance can pass from bacterium to
bacterium, and resistant bacterial infections can pass from person to person. Thus, antibiotic use
and antibiotic resistance can eventually affect an entire community. When antibiotics are used in
humans or animals, approximately 80 - 90% of the ingested antibiotics are not broken down, but
pass through the body intact and enter the environment as waste. Thus, they retain their ability to
affect bacteria and promote antibiotic resistance even after they enter the soil or water as a waste
product (General). Antibiotic resistance is having impact on not only humans, but also the
Although antibiotics should only be used if absolutely necessary, some people believe
that antibiotics are to be utilized whenever they are needed. Because antibiotics are seen as an
efficient way for individuals to recover quickly from sickness, doctors are often times convinced
by their patients to prescribe medication when it is not required. Many people continue to cling
to the notion of why not take something if theres even a chance that it will make me better?,
when in reality there are big risks, says Jason G. Newland, MD, medical director in charge of
patient safety at Childrens Mercy Hospital in Kansas City, Missouri. Risks that can land you in
the hospital (Pros & Cons). However, having this mindset can be very detrimental to a
person, as the overuse of antibiotics will eventually lead to the body resisting it and could even
cause harmful effects or death. Prescribing antibiotics is leading to longer hospital stays, higher
medical costs, increased mortality, and it is having impact on countries all around the world.
Antibiotic resistance is accelerated by the misuse and overuse of antibiotics, as well as
poor infection prevention and control. Steps can be taken at all levels of society to reduce the
impact and limit the spread of resistance (Antibiotic Resistance). The World Health Organization
(WHO) has become quite concerned about the rising levels of resistant bacteria in all areas of the
world. To provide some global coordination, WHO issued its Global Strategy for Containment
action to help contain antibiotic resistance. The epidemic of resistant bacteria has spurred
renewed interest in finding novel antibiotics. The process of producing a new antibiotic,
however, is long and expensive, requiring approximately ten years and $300 million to bring a
new antibiotic to market. One approach taken by scientists to combat antibiotic resistance is to
strengthen the action of existing antibiotics by modifying them so the bacterial enzymes that
cause resistance cannot attack them. An alternative approach to the antibiotic resistance problem
is to interfere with the mechanisms that promote resistance, rather than to attempt to kill the
bacteria. For example, interfering with the duplication or movement of a bacterium's genetic
material would eliminate the transfer of resistance genes between bacteria (General). By
actively finding new approaches to this issue, it shows that we are working towards a more
progressive future in antibiotics, underlining that this is a very real problem that needs to be
addressed.
Overprescribing antibiotics is a huge problem that is having negative effects on not only
the United States, but countries all over the world. It is threatening global health while
prolonging hospital stays, resulting in higher medical costs. Food security and mortality are also
being jeopardized due to mistreatment of antibiotics. It is something that could make treatment
for common illness and minor injuries much more complicated than a short trip to the doctors,