1. Grabe, M., Forsgren, A. & Bjrk, T.

Concentrations of ciprofloxacin in serum and

prostatic tissue in patients undergoing transurethral resection. Eur. J. Clin. Microbiol.
5, 211212 (1986).

2. Cussans, A., Somani, B. K., Basarab, A. & Dudderidge, T. J. The role of targeted
prophylactic antimicrobial therapy before transrectal ultrasonography-guided prostate
biopsy in reducing infection rates: a systematic review. BJU Int. 117, 725731 (2016).

o CAS

o PubMed

o Article

3. Liss, M. A., Kim, W., Moskowitz, D. & Szabo, R. J. Comparative effectiveness of

targeted versus empirical antibiotic prophylaxis to prevent sepsis from transrectal
prostate biopsy: a retrospective analysis. J. Urol. 194, 397402 (2015).

4. Taylor, A. K. et al. Targeted antimicrobial prophylaxis using rectal swab cultures in

men undergoing transrectal ultrasound guided prostate biopsy is associated with
reduced incidence of postoperative infectious complications and cost of care. J. Urol.
187, 12751279 (2012).

o CAS

o PubMed

o Article

5. Bloomfield, M. G., Page, M. J., McLachlan, A. G., Studd, R. C. & Blackmore, T. K.

Routine ertapenem prophylaxis for transrectal ultrasound guided prostate biopsy does
not select for carbapenem resistant organisms: a prospective cohort study. J. Urol.
http://dx.doi.org/10.1016/j.juro.2017.03.077 (2017).

6. Cerqueira, G. C. et al. Multi-institute analysis of carbapenem resistance reveals

remarkable diversity, unexplained mechanisms, and limited clonal outbreaks. Proc.
Natl Acad. Sci. USA 114, 11351140 (2017).

7. Patel, G., Huprikar, S., Factor, S. H., Jenkins, S. G. & Calfee, D. P. Outcomes of
carbapenem-resistant Klebsiella pneumoniae infection and the impact of antimicrobial
and adjunctive therapies. Infect. Control Hosp. Epidemiol. 29, 10991106 (2008).

o ISI

o PubMed

o Article
 8. World Health Organization. Global priority list of antibiotic-resistant bacteria to
guide research, discovery, and development of new antibiotics (WHO, 2017).

9. Davies, J. & Davies, D. Origins and evolution of antibiotic resistance. Microbiol.

Mol. Biol. Rev. 74, 417433 (2010).

o CAS

o ISI

o PubMed

o Article

10. Liss, M. A. et al. American Urological Association white paper on the prevention and
treatment of the more common complications related to prostate biopsy update. J.
Urol. http://dx.doi.org/10.1016/j.juro.2017.01.103 (2017).

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Affiliations
1. Deepak K. Pruthi and Michael A. Liss are at the Department of
Urology, University of Texas Health Science Center at San Antonio,
7703 Floyd Curl Drive, San Antonio, Texas 78229, USA.

Competing interests statement

The authors declare no competing interests.

Corresponding author
Correspondence to:

Michael A. Liss

Author details
Deepak K. Pruthi is a urologic oncology fellow at the University of Texas Health San
Antonio, Texas, USA. He graduated from the University of Winnipeg, Canada (BSc
 Biology, Biochemistry; BA Psychology). He went to medical school at the University
of Manitoba, Canada, where he obtained his MD and a medical research degree (BSc
Med). He completed his urology residency at the University of Manitoba. As he
completes his Society of Urologic Oncology-approved fellowship, he is also obtaining
a Master in Clinical and Translational Investigation. His primary research interests
include renal insufficiency, anatomical and pathology-based predictive modelling, and
examining oncological outcomes.

Michael A. Liss is a urologic oncologist and assistant professor at the University of

Texas Health San Antonio, Texas, USA. He graduated magna cum laude (BS in
Biology) from Benedictine University in Illinois, USA, received his medical degree
with honours in research from the Medical College of Wisconsin, USA, and
completed his urology residency at University of California Irvine, USA. He obtained
a Masters of Applied Science in Clinical Research during his Society of Urologic
Oncology-approved urologic oncology fellowship at University of California San
Diego, USA. His primary research interests include incorporating imaging and
biomarker translational research into interventional clinical trials, surgical education
and training, and infection prevention with antibiotic stewardship.