Additional explanation of IOOs chemical composition

1. This IOO is distilled from a species of Aquilaria tree because it contains a number of key
compounds of Agarwood essential oil. Namely, it contains a big amount (86.07%) of
Sesquiterpenes, Sesquiterpenoids and derivative of Sesquiterpene alcohol, but it doesnt
contain genuine Sesquiterpene alcohol (an isomer of C15H26O) and any fragrant Ketones,
especially it doesnt contain Benzylacetone (CAS 2550-26-7) that is an important specific
compound of essential oil distilled from Aquilaria crassna.
2. This IOO is mixed with a small amount (4.39%) of an extract of the fruit named Garcinia
cambogia Hort. Ex Boerl (see
compound No.8 and No.15 of
the Chemical composition of
Agarwood oil IOO). For more
information about this extract,
including hazard class division, please visit https://3bsccorp.com/organic-
chemicals/octasiloxane-1-1-3-3-5-5-7-7-9-9-11-11-13-13-15-15-hexadecamethyl-detail .
However, it was fortunate, this fruit is edible and its extract is benign.
3. Please focus your serious attention to the compound named Digitoxin (see No.14 of the
Chemical composition of Agarwood oil IOO), it is listed in the EHS (extremely
hazardous substances). For more information about Digitoxin and its synonyms, please
visit https://pubchem.ncbi.nlm.nih.gov/compound/6281#section=Handling-and-Storage
and https://en.wikipedia.org/wiki/Digitoxin. Besides, you should also pay attention to
the compound named Cyclooctasiloxane, hexadecamethyl- (see No.9 of the Chemical
composition of Agarwood oil IOO), it is a record in the TSCA candidate list of Chemical
substances (TSCA: Toxic Substances Control Act).

We hope the above explanation can help our client to properly evaluate the quality of the
IOO sample.

SECOIN APPLIED BIOTECH CENTER

59 Hang Chuoi street, Hai Ba Trung district, Hanoi, Vietnam
227 Dien Bien Phu street, Ward 15, Binh Thanh district, HCMc
Tel: 84-4-39718899, 84913207676; URL: http://agarwood.ning.com
http://www.secoin.vn; E-mail: dxb@secoin.vn; secoinbio@secoin.vn