Association/American
Stroke
Stroke: Highlights of Selected Articles 529
Stroke Association
Journal
ORIGINAL CONTRIBUTIONS
March 2017 Clinical Sciences
Volume 48 Epidemiology of Transient Ischemic Attacks Using Time- or Tissue-Based Definitions: 530
Number 3 A Population-Based Study
DianaDegan, MD; RaffaeleOrnello, MD; CindyTiseo, MD; FedericaDe Santis, MD; FrancescaPistoia, MD, PhD;
AntonioCarolei, MD; SimonaSacco, MD
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Mild Hypokalemia and Supraventricular Ectopy Increases the Risk of Stroke in 537
Community-Dwelling Subjects
NickMattsson, MD; PremanKumarathurai, MD; Bjrn StrierLarsen, BSc; OlavWendelboeNielsen, MD, PhD, DMSc;
AhmadSajadieh, MD, DMSc
Declining Incidence of Ischemic Stroke: What Is the Impact of Changing Risk 544
Factors? The Troms Study 1995 to 2012
AnneM.Vangen-Lnne, MD; TomWilsgaard, PhD; SteinHaraldJohnsen, MD, PhD; Maja-LisaLchen, MD, PhD;
IngerNjlstad, MD, PhD; EllisivB.Mathiesen, MD, PhD
Timing of Incident Stroke Risk After Cervical Artery Dissection Presenting 551
Without Ischemia
NicholasA.Morris, MD; AlexanderE.Merkler, MD; GinoGialdini, MD; HoomanKamel, MD
Large Vessel Occlusion Scales Increase Delivery to Endovascular Centers Without 568
Excessive Harm From Misclassifications
HenryZhao, MBBS; SkyeCoote, MN; LaurenPesavento, BN; LeonidChurilov, PhD; HelenM.Dewey, PhD;
StephenM.Davis, MD; BruceC.V.Campbell, PhD
Risk of Acute Stroke After Hospitalization for Sepsis: A Case-Crossover Study 574
AmeliaK.Boehme, PhD, MSPH; PurnimaRanawat, MPH; Jorge Luna, MS; Hooman Kamel, MD;
MitchellS.V.Elkind, MD, MS
CME
On the Cover: The image is taken from an article in this issue, Acute Cerebral Venous Thrombosis: Three-Dimensional
Visualization and Quantification of Hemodynamic Alterations Using 4-Dimensional Flow Magnetic Resonance Imaging by
Schuchardt et al (Stroke. 2017;48:671677. doi: 10.1161/STROKEAHA.116.015102). The image is Figure 1.
OPEN ACCESS
Specific Lobar Affection Reveals a Rostrocaudal Gradient in Functional Outcome in 587
Spontaneous Intracerebral Hemorrhage
StefanT.Gerner, MD; JojiB.Kuramatsu, MD; SebastianMoeller, MD; AngelikaHuber, MD; HannesLcking, MD;
StephanP.Kloska, MD; DominikMadar, MD; JochenA.Sembill, MD; StefanSchwab, MD; HagenB.Huttner, MD
Lifestyle Factors and Early Clinical Outcome in Patients With Acute Stroke: 611
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A Population-Based Study
AnnetteIngeman, PhD; GretheAndersen, DMSci; ReimarW.Thomsen, PhD; HeidiH.Hundborg, PhD;
HenrikH.Rasmussen, PhD; Sren P.Johnsen, PhD
Use of a 3-Item Short-Form Version of the Barthel Index for Use in Stroke: 618
Systematic Review and External Validation
RachaelL.MacIsaac, PhD; MyzoonAli, PhD; MartinTaylor-Rowan, MSc; HelenRodgers, FRCP;
KennedyR.Lees, FRCP; TerenceJ.Quinn, MD; on behalf of the VISTA Collaborators
Impact of Expanding the Prehospital Stroke Bypass Time Window in a Large 624
Geographic Region
IanG.Stiell, MD, MSc; CatherineM.Clement, RN; KristyCampbell, PCP; MukulSharma, MD; DougSocha, PCP, BSc, MA;
MarcoL.A.Sivilotti, MD, MSc; AlbertJin, MD; JeffreyJ.Perry, MD; JimLumsden, BScPT, MPA; CallyMartin, BScPT, MSc;
MarkFroats, MD; RichardDionne, MD; JohnTrickett, RN, BScN
The Basilar Artery on Computed Tomography Angiography Prognostic Score for 631
Basilar Artery Occlusion
FanaAlemseged, MD; DarshanG.Shah, MBBS; MarinaDiomedi, MD; FabrizioSallustio, MD;
AndrewBivard, PhD; GaganSharma, MCA; PeterJ.Mitchell, MD; RichardJ.Dowling, MBBS; StevenBush, MBBS;
BernardYan, MBBS; CarloCaltagirone, MD; RobertoFloris, MD; MarkW.Parsons, MBBS, PhD;
ChristopherR.Levi, MBBS; StephenM.Davis, MD; BruceC.V.Campbell, MBBS, PhD
Histopathological Differences Between the Anterior and Posterior Brain Arteries 638
as a Function of Aging
WilliamRoth, MD; SusanMorgello, MD; JamesGoldman, MD; JayP.Mohr, MD; MitchellS.V.Elkind, MD, MS;
RandolphS.Marshall, MD, MS; JoseGutierrez, MD, MPH
Validating a Predictive Model of Acute Advanced Imaging Biomarkers in Ischemic Stroke 645
AndrewBivard, PhD; ChristopherLevi, FRACP; LongtingLin, PhD; XinCheng, FRACP; RichardAviv, FRACP;
NeilJ.Spratt, PhD, FRACP; MinLou, PhD, FRACP; TimKleinig, PhD, FRACP; BillyOBrien, FRACP;
KennethButcher, FRACP; JingfenZhang, FRACP; JimJannes, FRACP; QiangDong, FRACP; MarkParsons, PhD, FRACP
Vessel Wall Enhancement and BloodCerebrospinal Fluid Barrier Disruption After 651
Mechanical Thrombectomy in Acute Ischemic Stroke
ArturoRen, MD; CarlosLaredo, MSc; AntonioLopez-Rueda, MD; LauraLlull, MD; RalTudela, PhD; LuisSan-Roman, MD;
XabierUrra, MD; JordiBlasco, MD; JuanMacho, MD; LauraOleaga, MD; AngelChamorro, MD; SergioAmaro, MD
OPEN ACCESS
Multiparametric Magnetic Resonance Imaging for Prediction of Parenchymal 664
Hemorrhage in Acute Ischemic Stroke After Reperfusion Therapy
KambizNael, MD; JamesR. Knitter, BS; RezaJahan, MD; JefferyGornbein, DrPH; ZahraAjani, MD;
LeiFeng, MD, PhD; BrettC.Meyer, MD; LeeH.Schwamm, MD; AlbertJ.Yoo, MD; RandolphS.Marshall, MD;
PhilipM.Meyers, MD; DileepR.Yavagal, MD; MaxWintermark, MD; DavidS.Liebeskind, MD; JudyGuzy, RN;
SidneyStarkman, MD; JeffreyL.Saver, MD; ChelseaS.Kidwell, MD
Magnetic Resonance Imaging Plaque Hemorrhage for Risk Stratification in Carotid 678
Artery Disease With Moderate Risk Under Current Medical Therapy
AkramA.Hosseini, MD, PhD; RichardJ.Simpson, PhD; NishathAltaf, MBChB, PhD; PhilipM.Bath, DSc, FMedSci;
ShaneT.MacSweeney, MAMB, MChir; DorotheeP.Auer, MD
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Coexistent Sickle Cell Disease Has No Impact on the Safety or Outcome of Lytic 686
Therapy in Acute Ischemic Stroke: Findings From Get With The Guidelines-Stroke
RobertJ.Adams, MS, MD; MargueritteCox, MS, MGIST; ShellyD.Ozark, MD; JulieKanter, MD; PhillipJ.Schulte, PhD;
YingXian, MD, PhD; GreggC.Fonarow, MD; EricE.Smith, MD, MPH; LeeH.Schwamm, MD
YAMATO Study (Tissue-Type Plasminogen Activator and Edaravone Combination Therapy) 712
JunyaAoki, MD; KazumiKimura, MD; NaomiMorita, MD; MasafumiHarada, MD; NorifumiMetoki, MD;
YoheiTateishi, MD; KenichiTodo, MD; HiroshiYamagami, MD; KoujiHayashi, MD; YukaTerasawa, MD;
KojiFujita, MD; NobuakiYamamoto, MD; IchiroDeguchi, MD; NorioTanahashi, MD; TakeshiInoue, MD;
TakeshiIwanaga, MD; NobuyukiKaneko, MD; HidetakaMitsumura, MD; YasuyukiIguchi, MD; YasushiUeno, MD;
YojiKuramoto, MD; ToshiyasuOgata, MD; ShigeruFujimoto, MD; MutsumiYokoyama, MD; ShinjiNagahiro, MD;
on behalf of the YAMATO Study Investigators
DATA SUPPLEMENT
CME
OPEN ACCESS
Prediction of Early Recurrent Thromboembolic Event and Major Bleeding in Patients 726
With Acute Stroke and Atrial Fibrillation by a Risk Stratification Schema: The ALESSA
Score Study
MaurizioPaciaroni, MD; GiancarloAgnelli, MD; ValeriaCaso, MD, PhD; GeorgiosTsivgoulis, MD; KarenL.Furie, MD;
PrasannaTadi, MD; CeciliaBecattini, MD; NicolaFalocci, PhD; MarialuisaZedde, MD; AzmilH.Abdul-Rahim, MD;
KennedyR.Lees, MD; AndreaAlberti, MD; MicheleVenti, MD, PhD; MonicaAcciarresi, MD; CataldoDAmore, MD;
MariaGiuliaMosconi, MD; LudovicaAnnaCimini, MD; AntonioProcopio, MD; PaoloBovi, MD; MonicaCarletti, MD;
AlbertoRigatelli, MD; ManuelCappellari, MD; JukkaPutaala, MD; LiisaTomppo, MD, PhD; TurgutTatlisumak, MD;
FabioBandini, MD; SimonaMarcheselli, MD; AlessandroPezzini, MD; LorisPoli, MD; AlessandroPadovani, MD, PhD;
LucaMasotti, MD; VieriVannucchi, MD; Sung-IlSohn, MD, PhD; GianniLorenzini, MD; RossanaTassi, MD;
FrancescaGuideri, MD; MaurizioAcampa, MD; GiuseppeMartini, MD; GeorgeNtaios, MD; EfstathiaKaragkiozi, MD;
GeorgeAthanasakis, MD; KostantinosMakaritsis, MD; KostantinosVadikolias, MD; ChrysoulaLiantinioti, MD;
MariaChondrogianni, MD; NicolaMumoli, MD; DomenicoConsoli, MD; FrancoGalati, MD; SimonaSacco, MD;
AntonioCarolei, MD; CindyTiseo, MD; FrancescoCorea, MD, PhD; WalterAgeno, MD; MartaBellesini, MD;
GiovannaColombo, MD; GiorgioSilvestrelli, MD, PhD; AlfonsoCiccone, MD; UmbertoScoditti, MD; LiciaDenti, MD;
MichelangeloMancuso, MD; MiriamMaccarrone, MD; GiovanniOrlandi, MD; NicolaGiannini, MD; GinoGialdini, MD;
TizianaTassinari, MD; MariaLuisaDe Lodovici, MD; GiorgioBono, MD; ChristinaRueckert, MD; AntonioBaldi, MD;
SebastianoDAnna, MD; DaniloToni, MD, PhD; FedericaLetteri, MD; MartinaGiuntini, MD; EnricoMariaLotti, MD;
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Roles of Changing Physical Function and Caregiver Burden on Quality of Life in 733
Stroke: A Longitudinal Dyadic Analysis
GianlucaPucciarelli, RN, MSN; ErcoleVellone, PhD; SerenellaSavini, PhD; SilvioSimeone, PhD; DavideAusili, PhD;
RosariaAlvaro, MSN; ChristopherS.Lee, PhD; KarenS.Lyons, PhD
Basic Sciences
MicroRNA-1792 Cluster in Exosomes Enhance Neuroplasticity and Functional 747
Recovery After Stroke in Rats
HongqiXin, PhD; MarkKatakowski, PhD; FengjieWang, MS; Jian-YongQian, PhD; XianShuangLiu, PhD;
MeserM.Ali, PhD; BenjaminBuller, PhD; ZhengGangZhang, MD, PhD; MichaelChopp, PhD
Role of Genetic Variation in Collateral Circulation in the Evolution of Acute Stroke: 754
A Multimodal Magnetic Resonance Imaging Study
Yu-ChiehJillKao, PhD; EstebanA.Oyarzabal, MS; HuaZhang, MD; JamesE.Faber, PhD; Yen-YuIanShih, PhD
Genome-Wide Analysis of the Circulating miRNome After Cerebral Ischemia Reveals 762
a Reperfusion-Induced MicroRNA Cluster
StefanUhlmann, PhD; EvaMracsko, MD, PhD; EhsanJavidi, MD; SarahLamble, PhD; AnaTeixeira, PhD;
AgnesHotz-Wagenblatt, PhD; Karl-HeinzGlatting, PhD; RolandVeltkamp, MD
BRIEF REPORTS
Stroke With Unknown Time of Symptom Onset: Baseline Clinical and Magnetic
Resonance Imaging Data of the First Thousand Patients in WAKE-UP (Efficacy and
Safety of MRI-Based Thrombolysis in Wake-Up Stroke: A Randomized, Doubleblind, 770
DATA SUPPLEMENT Placebo-Controlled Trial)
GtzThomalla, MD; FlorentBoutitie, PhD; JochenB.Fiebach, MD; ClausZ.Simonsen, MD, PhD;
NorbertNighoghossian, MD; SalvadorPedraza, MD, PhD; RobinLemmens, MD; PascalRoy, MD; KeithW.Muir, MD;
MartinEbinger, MD; IanFord, PhD; BastianCheng, MD; IvanaGalinovic, MD; Tae-HeeCho, MD;
CME JosepPuig, MD, PhD; VincentThijs, MD; MatthiasEndres, MD; JensFiehler, MD; ChristianGerloff, MD;
on behalf of the WAKE-UP Investigators
OPEN ACCESS
Cervical Carotid Pseudo-Occlusions and False Dissections: Intracranial Occlusions 774
Masquerading as Extracranial Occlusions
JonathanA.Grossberg, MD; DiogoC.Haussen, MD; FabricioB.Cardoso, MD; LeticiaC.Rebello, MD;
MehdiBouslama, MD; AaronM.Anderson, MD; MichaelR.Frankel, MD; RaulG.Nogueira, MD
Do Women With Atrial Fibrillation Experience More Severe Strokes?: Results From 778
the Austrian Stroke Unit Registry
ClemensLang; LeonhardSeyfang, MoS; JuliaFerrari, MD; Thomas Gattringer, MD; StefanGreisenegger, MD;
KarinWilleit, MD; ThomasToell, MD; StefanKrebs, MD; MichaelBrainin, MD; StefanKiechl, MD; JohannWilleit, MD;
WilfriedLang, MD; MichaelKnoflach, MD; for the Austrian Stroke Registry Collaborators
Risk Factors of Subacute Thrombosis After Intracranial Stenting for Symptomatic 784
Intracranial Arterial Stenosis
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XuanSun, MD; XuTong, MD; WaiTingLo, MBBS; DapengMo, MD; FengGao, MD; NingMa, MD; BoWang, MD;
ZhongrongMiao, MD
Automated Software System to Promote Anticoagulation and Reduce Stroke Risk: 787
Cluster-Randomized Controlled Trial
TimA.Holt, PhD; AndrewDalton, PhD; TomMarshall, PhD; MatthewFay, MBChB; NadeemQureshi, DM;
SusanKirkpatrick, MA; JennyHislop, PhD; DanielLasserson, MD; KarenKearley, MBChB; JillMollison, PhD;
Ly-MeeYu, DPhil; F.D.RichardHobbs, FMedSci; DavidFitzmaurice, MD
Drip n Ship Versus Mothership for Endovascular Treatment: Modeling the Best 791
Transportation Options for Optimal Outcomes
MatthewS.W.Milne, BSc (In Progress); JessalynK.Holodinsky, MSc; MichaelD.Hill, MD, MSc; AndersNygren, PhD;
ChaoQiu, PhD; MayankGoyal, MD; NoreenKamal, PhD
Proportional Motor Recovery After Stroke: Implications for Trial Design 795
CathyM.Stinear, PhD; WinstonD.Byblow, PhD; SuzanneJ.Ackerley, PhD; Marie-ClaireSmith, BHSc;
VictorM.Borges, PhD; P.AlanBarber, PhD, FRACP
SPECIAL REPORT
DATA SUPPLEMENT
Stroke Recovery and Rehabilitation Research: Issues, Opportunities, and the National 813
Institutes of Health StrokeNet
StevenC.Cramer, MD; StevenL.Wolf, PhD; HaroldP.Adams, Jr, MD; DaofenChen, PhD;
CME
AlexanderW.Dromerick, MD; KariDunning, PT, PhD; CaitlynEllerbe, PhD; AndrewGrande, MD; ScottJanis, PhD;
MaartenG.Lansberg, MD; RonaldM.Lazar, PhD; YukoY.Palesch, PhD; LorieRichards, PhD; ElliotRoth, MD;
SeanI.Savitz, MD; LawrenceR.Wechsler, MD; MaxWintermark, MD; JosephP.Broderick, MD
OPEN ACCESS
TOPICAL REVIEW
Transcranial Direct Current Stimulation in Poststroke Aphasia Recovery 820
SusanWortman-Jutt, MS, CCC-SLP; DylanJ.Edwards, PhD
Letter by Tsuda Regarding Article, Combined Effects of Inflammatory Status and e93
Carotid Atherosclerosis: A 12-Year Follow-Up Study
KazushiTsuda, MD
Response by Mayer and Hoke to Letter Regarding Article, Combined Effects of e94
Inflammatory Status and Carotid Atherosclerosis: A 12-Year Follow-Up Study
FlorianJ.Mayer, MD; MatthiasHoke, MD
CORRECTIONS
Correction to: Clinical Selection Strategies to Identify Ischemic Stroke Patients With e95
Large Anterior Vessel Occlusion: Results From SITS-ISTR (Safe Implementation of
Thrombolysis in Stroke International Stroke Thrombolysis Registry)
Correction to: Sex Differences and Functional Outcome After Intravenous Thrombolysis e97
DATA SUPPLEMENT Correction to: Cerebral Microbleeds as Predictors of Mortality: The Framingham Heart Study e98
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48 (3)
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