MCQs for industrial pharmacy.

1. Interfacial tension is decreased by the addition of what?

a. Surfactants
b. Wetting agents
c. Emulsifiers
d. Suspending agent
e. Both A and B and c

2. One of the major problems encountered with suspensions is ________ which is referred to as
formation of hard settlements that are not redispersible
a. Sedimentation
b. Aggregation
c. Caking
d. Trituration
e. Phase inversion

3. Sedimentation can be delayed by which of the following:

a. Increasing the viscosity
b. Decreasing the particle size
c. Both A and B
d. None

4. Which of the following is NOT a method for determining emulsion type:

a. Dye test
b. Dilution test
c. Filter paper test
d. Conductivity test
e. Water attack test

5. Mechanical equipments for emulsification include:

a. Mechanical stirrers
b. Homogenizers
c. Ultra sonifiers
d. Colloid mills
e. All of the above

6. Fluid emulsions are a result of:

a. Low levels of internal phase
b. High levels of internal phase
c. High level of water
d. Low level of water

7. Semisolid system in which a liquid phase is constrained within 3 dimensional polymeric matrix in
which degree of physical cross linking has been introduced is known as:
a. Ointments
b. Gels
c. Creams
 d. Pastes

8. For a topically applied drug there are _______ routes of entry of drug into the circulation.
a. 2
b. 3
c. 4
d. 5
e. 6

9. _______ emulsifiers are employed for both oil in water and water in oil emulsified
pharmaceutical semisolids.
a. Cationic emulsifiers
b. Anionic emulsifiers
c. Non-ionic emulsifiers
d. Both cationic and anionic emulsifiers can be used
e. Both non-ionic and anionic emulsifiers can be used

10. Pastes are dispersions of high concentrations of insoluble powdered substances, ranging from
_________ in fatty or aqueous base
a. 20 - 50 %
b. 50 - 100 %
c. 25 - 55 %
d. 30 - 60 %
e. 40 - 100 %

f. Which of the following is TRUE:

a. 1 centipoise = 0.01 poise
b. 1 poise = 0.01 poise
c. 1 centipoise = 0.1 poise
d. 1 poise = 0.1 centipoise

11. To operate effectively, a ball charge from _______________ of the volume of the mill is
required.
a. 20 50 %
b. 30 50 %
c. 50 %
d. 15 50 %
e. Upto 50 %

12. In dry milling, the moisture level should be _________.

a. More than 2%
b. Less than 2%
c. Less than 1%
d. More than 1%
e. Less than 3%

13. Selection of a mill for communition depends on which of the following factors:
a. Product specifications
 b. Capacity of the mill and production rate requirement
c. Dust control
d. Sanitation
e. Batch or continuous operation
f. All of the above

14. The addition of less Than 0.1 % surface active agents may increase the production rate of a ball
mil ____________.
a. 20 50 %
b. 20 40 %
c. 10- 40 %
d. 10 50 %
e. 20 %

15. Which of the following type of mills would be used for fine grinding of abrasive material and not
for soft material:
a. Cutter
b. Revolving
c. Hammer
d. Roller
e. Attrition

16. Which of the following type of mills would be used for crude animal and vegetable drugs?
a. Cutter
b. Revolving
c. Hammer
d. Roller
e. Attrition

17. What is the principle of micronizer (fluid energy mill)?

a. Cutting
b. Rolling
c. Attrition
d. Impact
e. Attrition and impact

18. __________ forces depend on the size, geometry and conformation of molecules adsorbed on
surface.
a. Born repulsive forces
b. Adhesive forces
c. Steric repulsive forces
d. Repulsive hydration forces
e. Van der Waals repulsive forces

19. The strong effect of valence of the electrolyte on the double layer repulsive force is known as
_______________.
a. DLVO theory
b. Schulze hardy rule
 c. Hofmeister series
d. Gibbs theory

20. Tumbling mixer includes which of the following:

a. Ribbon blender
b. Helical flight mixer
c. Both A and B
d. Twin shell mixer
e. Kneader

21. _____________ are efficient in de-aggregation of solids, but inefficient in distribution of

particles uniformly through the entire mass.
a. Roller mills
b. Kneaders
c. Mulling mixers
d. Cubic mixer
e. Cylindrical mixer

22. Which of the following is method of heat transfer:

a. Conduction
b. Convection
c. Radiation
d. All of the above

23. The potential difference across all the ion layers from the particle surface into the solution is
known:
a. Nernst electro thermodynamic
b. Electrochemical potential
c. Epsilon potential
d. All of the above
e. Zeta potential

24. The potential difference between the immobile layer of ions and the mobile layer is termed as:
a. Electrokinetic potential
b. Zeta potential
c. Both A and B
d. Epsilon potential
e. Stern potential

25. Which of the following statement is true:

a. The potential between the particle surface and the immobile layer is stern potential
b. Stern potential is equal to the difference between the electrochemical and zeta potential
c. Zeta potential is measured with the help of electrophoresis cell
d. The direction in which the particles migrate indicate the sign of the charge borne by them
e. All of the above

26. The ________ the zeta potential, the _________ the repulsion.
a. Higher, higher
b. Lower, lower
c. Both A and B
d. Lower, higher
e. Higher, lower

27. Brufen suspension may be classified as which type of mixture:

a. Positive mixture
b. Negative mixture
c. Neutral mixture
d. It is not a mixture

28. The most widely used mixer for liquids is:

a. Propeller mixers
b. Shaker mixers
c. Turbine mixers
d. Paddle mixers
e. Agitator mixer

29. The fire caused by flammable liquids is classified in:

a. Class A
b. Class B
c. Class C
d. Class D
e. Class K

30. The fire caused by combustible metals such as Mg, Na, K, Ti is classified as :
a. Class A
b. Class B
c. Class C
d. Class D
e. Class K