.

Stockholm, Sweden
17177

Dear D r . -

Thank you for your correspondence, and for the stimulating ideas you presented.

You asked about how I chose the company name when I founded Gilead Sciences.
My college minor was in English literature, and I tried to continue reading non-
science literature when I was in medical school at Johns Hopkins. I came across a
play by the American playwright Lanford Wilson, called Balm in Gilead. I. read the
play and wondered what was the "balm" it referred to. It was also at this time that I
was becoming keenly interested in the field of nucleic acid chemistry and the
burgeoning techniques for modifying the native structure of DNA and its building
blocks-the basis of Gilead's research. I continued to investigate the nucleic acid
field when I went to business school just after medical school, and would cross the
bridge to the other side of the Charles River once a week to read the latest journals
at the Harvard bio library, but that is another story ...

Lanford Wilson's title came from a reference in the Old Testament. When I dug a
little deeper, I found that the balm had an authentic historical basis, and was an
extract from certain trees found in a region of the ancient Middle East called Gilead,
near the Jordan River. It turns out that in modern times the likely plant source of the
balm has been analyzed and found to contain analgesic salicylates including
acetylsalicylic acid, which is aspirin. So the balm of Gilead_was probably one of
mankind's first genuine therapeutics.

Three years after medical school, when I started the company, I thought Gilead
would be a fine name, but I first needed to clear the rights, so I incorporated under a
"place-holder" name and then officially changed to Gilead Sciences a few months
later, in early 1988. I added "Sciences" because I wanted it to be clear that the
company was based on rigorous research and scientific principles.

Let me know if you have any other questions, and please keep me informed of your
results.

Cordially,

Michael L. Riordan, M.D.