TM Paper Code
(1001CPE401617002) )0//0CPE4/0607//1)
CAREER INSTITUTE
Path to Success KOTA (RAJASTHAN) FORM NUMBER
3. Section-A consist of 60 Questions and total marks are 60. There is 1 mark for each correct answer and 0.25
Negative marking for each incorrect answer.
4. Section-B consist of total 8 Questions and total marks are 40. There are 5 marks for each correct answer and No
Negative marking.
5. Student must abide by the instructions issued during the examination, by the invigilators or the centre incharge.
6. Before attempting the question paper ensure that it contains all the pages and that no question is missing.
7. A candidate has to write his / her answers in the OMR sheet by darkening the appropriate bubble with the help of
Blue / Black Ball Point Pen only as the correct answer(s) of the question attempted.
Corporate Office
SANKALP, CP-6, Indra Vihar, Kota (Rajasthan)-324005
+91 - 744 - 5156100 info@allen.ac.in
Website: www.allen.ac.in
(4) 0.49 N
CHEMISTRY
16. Which of the following graphs is correct for
photoelectric effect ?
r r r
(a) R + T + W = 0 (b) T2 = R2 + W2 v v
3 5
Table 1
Ion [Intracellular] [Extracellular] +E ion 2
Na+ 15 mM 140 mM +58mV 1 8
80 6
K+ 135 mM mM -92mV 7
+Eion = Equilibrium potential for the ion Time (msec)
If the Em transiently changes from its resting (i). The threshold potential for the generation of
value, an electrical signal is generated in the an action potential can be found at that value
nerve cell. There are two types of electrical
of the Em where the:
signals: graded potentials and action potentials
(AP). Graded potentials are signals that operate (1) influx of K balances the efflux of Na.
over short distances, while action potentials are
(2) efflux of K is 10 times greater than the
signals that operate over long distances.
influx of Na.
Along the plasma membrane of a nerve cell
are voltage-sensitive Na and K channels that (3) efflux of K balances the influx of Na.
contain gates. The Na channel has an m gate
(4) influx of Na is 10 times greater than the
that opens quickly and an h gate that closes
slowly upon depolarization. The K channel efflux of K.
has an n gate that opens slowly upon (ii). The threshold potential for the action potential
depolarization. The Na gate can be blocked shown in Figure 1 is:
by tetrodotoxin (TTX), and the K gate can be
blocked by tetraethylammonium (TEA). In the (1) 50 mV (2) 65 mV
resting state the Na and K channels have their (3) 80 mV (4) 92 mV
gates arranged as shown in Figure 1:
1001CPE401617002 Your Hard Work Leads to Strong Foundation 7/10
PRE-NURTURE & CAREER FOUNDATION DIVISION 15-05-2017
(iii). During depolarization, the quick opening of enzyme that synthesizes it, glutamic acid
the voltage dependent m gates results in all of decarboxylase. Secondly, a deficiency of the
the following EXCEPT: enzyme choline acetylase leads to decreased
(1) an influx of Na ions. levels of the excitatory neurotransmitter,
(2) an increase in the opening of fast m gates acetylcholine. The delicate homeostatic
in neighboring Na channels. balance between the two neurotransmitters is
(3) an increase in the opening of fast n gates in disrupted. These deficiencies are thought to
neighboring K channels. lead to the observed characteristic movements
and mental symptoms of Huntington's disease.
(4) an absolute refractory period.
(i). Based on information in the passage,
(iv). Which of the following voltage gated positions
Huntington's disease is:
best represents the repolarization phase?
(1) m gate open; n gate open. (1) more common in men than in women.
(2) m gate closed; n gate open. (2) more common in women than in men.
(3) m gate open; n gate open. (3) equally common in both men and women.
Huntington's disease is a relatively rare disease (3) the parasympathetic nervous system.
that causes progressive degeneration of the (4) voluntary movements.
cerebral cortex and the basal ganglia of the (iii). The following molecule is referred to as GABA.
brain. The basal ganglia are masses of neuron What is its IUPAC name?
cell bodies (gray matter) located deep within
1
the cerebrum. Within the basal ganglia, certain H3 N CH 2 CH 2 CH 2 CO O
types of neurons are destroyed, while others
remain intact. (1) g-amino butyrate
Huntington's disease is a genetic disorder (2) 3-amino butanoic acid
caused by an autosomal dominant genetic (3) 1-amino butyrate
defect on the tip of chromosome 4. The (4) 4-aminobutanoic acid
symptoms of the disease are choreiform
(iv). Which amino acid is the precursor to GABA?
movements (rapid, uncontrolled, jerky
movements), mental deterioration, and (1) Histidine
emotional disturbances. The disease is (2) Leucine
relentless and usually leads to complete (3) Tyrosine
dehabilitation and death within 15 years of its
(4) Glutamate
onset. The age of onset is usually from 35-50
(v). In what structure of the neuron are
years, usually after the patient has had children.
neurotransmitters stored?
The proposed mechanism of the defect lies with
(1) The synaptic cleft.
certain neurotransmitters and is twofold. First
of all, there is a decreased level of g- (2) The vesicles of presynaptic neurons.
aminobutyric acid, an inhibitory (3) The receptors of postsynaptic neurons.
neurotransmitter, and a decreased level of the (4) The vesicles of postsynaptic neurons.