August 2011
treatment are clearly described in the text with reference
to nicely laid-out figures and tables. Novel hot topics in
this field, such as the use of vaptans for hyponatremia and
ascites, implications of cardiorenal syndrome, use of novel
vasoconstrictors, and transhepatic portosystemic shunt
for HRS, are appropriately addressed and provide up-to-
date data and literature for the reader. The chapter on the
role of infections in the development of HRS is a bona
fide highlight and could stand alone as a review paper for
any major gastroenterology or hepatology journal.
Despite these strengths related to individual chapters,
there are significant issues with the approach taken by the
editors to cover the topics in detail. First, this book reads
more like a series of single topic reviews and does not flow
well from chapter to chapter or subject to subject. Many
of the chapters overlap in content and style, particularly
in the pathophysiology of portal hypertension, hyperdy-
namic circulation, renal vasoconstriction, and fluid reten-
tion. An initial chapter providing an extensive review of
these mechanisms, starting from the onset of portal hy-
pertension to late renal dysfunction, would have been a
more preferable preamble to all 3 subjects having com-
mon pathways and mediators. In addition, the chapters
should have been edited to remove repetitive statements
and figures to allow enhanced focus and detail on each
specific subject. Another concern is the number of chap-
ters and heavy emphasis on terlipressin therapy for HRS.
Although each serves as a reasonable review, only 1 chap-
ter at best is needed for discussion of this agent in parallel
with the preceding vasoconstrictor therapy chapter, be-
cause terlipressin is mainly used in European countries
and has not shown survival benefits to date. Finally, the
tables in many of the chapters are difficult to read and
follow owing to their stretched-out format and could
have been more suitably condensed and displayed. Some
of the chapters could have also used additional, more
concise tables or figures instead of the lengthy text pro-
vided.
With an overemphasis on plasma expanders and spe-
cific agents (terlipressin), this book fails to elaborate on or
cover key principles of other important topics. The initial
chapters on ascites and hyponatremia could have been
expanded to discuss mechanisms and differential diagno-
ses more comprehensively. The chapter on renal failure in
cirrhosis is well written, but is too strong in its statements
on controversial subjects, such as the use of renal biopsy
(mandatory if the glomerular filtration rate is 1530
mL/min) and the selection criteria for combined liver
kidney transplantation. Finally, highly relevant subjects
were only mentioned in scattered form throughout the
textbook and should have been covered in greater detail as
separate chapters: Portal hypertensive bleeding and circu-
latory dysfunction/HRS; hepatic encephalopathyrelation-
ship to volume contraction/HRS; the recovery of cardiac
dysfunction, hyponatremia, and ascites after liver transplan-
tation (not just HRS which is covered adequately); and dif-
ficulties with measuring glomerular filtration rate in the
cirrhotic population. These are all important topics that are
PRINT AND MEDIA REVIEWS 777
clearly under the umbrella of the books aims and are not
sufficiently explored within the text.
Bottom Line: This book excels in providing detailed
reviews of select topics associated with hyponatremia,
ascites, and HRS for gastroenterologists, hepatologists,
and transplant providers. However, given the book is
meant to be read in its entirety (200 pages) and as not
a reference text, it lacks the flow, cohesiveness, and bal-
ance of topics that would be expected for such an under-
taking.
JOSH LEVITSKY
Division of Gastroenterology and
Comprehensive Transplant Center
Northwestern University Feinberg School
of Medicine
Chicago, Illinois
Meyers Dynamic Radiology of the Abdomen: Normal
and Pathologic Anatomy, 6th edition. Morton A. Meyers,
Chusilp Charnsangavej, and Michael Oliphant, editors. 800 pp.
$269.00. New York, New York, Springer, 2011. ISBN: 978-1-
4419-5938-6. Web address for ordering: www.springer.com
The sixth edition of Meyers Dynamic Radiology of the Abdo-
men, published by Springer, is a monumental work on
radiologic anatomy of the abdomen and radiologic imag-
ing of the spread of abdominal disease. Like the previous
5 editions of this text, the aim of the current edition is to
provide a systematic approach to the cross-sectional anat-
omy and dynamic principles for disease spread in the
abdomen. The previous editions were invaluable additions
to the radiology literature, and the sixth edition lives up
to the very high standards of its predecessors. This beau-
tifully written and amply illustrated text shows how the
myriad of anatomic structures in the abdomen every-
thing from the stomach, small bowel, colon, liver, pan-
creas, spleen, and kidneys to the mesentery, omentum,
and other ligamentous attachmentsinterrelate anatom-
ically to create the various intraperitoneal and extraperi-
toneal compartments in the abdomen. Once readers have
grasped both the fundamentals and nuances of these
complex anatomic interrelationships, it is possible to ap-
preciate how inflammatory, infectious, and malignant dis-
eases spread in the abdomen not in some random fashion,
but rather via predictable pathways directly related to the
structural anatomy and other dynamic principles.
The text begins with sections on the embryology and
anatomy of the abdomen, including all of the structures
in the subperitoneal space and peritoneal cavity. Within
this framework, the text then delves into the mechanisms
of spread of disease via mesenteric planes and reflections
as well as a host of lymphatic, peritoneal, perineural,
transvenous, and intraductal pathways, creating a coher-
ent, logical, and systematic approach for understanding
how diseases develop and spread in the abdomen.
778 CORRECTIONS GASTROENTEROLOGY Vol. 141, No. 2

First and foremost, this is a radiology text, and it
utilizes the entire armamentarium of state-of-the-art ab-
dominal imaging, including plain radiographs, fluoro-
scopic barium studies, ultrasonography, computed to-
mography, magnetic resonance imaging, and positron
emission tomography, to illustrate and elucidate the path-
ways of disease spread in the abdomen and pelvis. The
radiologic images are supplemented by carefully anno-
tated cross-sectional anatomic specimens and line draw-
ings, enabling readers to correlate the anatomic and im-
aging findings in a way that enhances their understanding
of the structural anatomy and pathology underlying
spread of disease in the abdomen.
Dr. Morton Myers, the first and long-time author of the
text, is among the true giants in abdominal radiology. It is
particularly impressive that so much of the material in the
text is derived from his own seminal studies encompass-
ing an extraordinary body of work, so no one is better
qualified to write this text than Dr. Meyers. For the sixth
edition, he has taken on 2 new co-authors, Dr. Chusilp
Charnsangavej and Dr. Michael Oliphant, who are them-
selves world-class experts in their field.
Bottom Line: Meyers Dynamic Radiology of the Abdomen
is essential reading for all radiologists-in-training, abdom-
inal imaging fellows, and practicing radiologists whose
daily work includes some form of abdominal imaging,
and this text belongs on the shelf of all radiology libraries.
However, it is an equally valuable tome for gastroenterol-
ogists, surgeons, or clinicians whose interests include ab-
dominal diseases and their mechanisms of spread in the
abdomen. Meyers Dynamic Radiology of the Abdomen has
long been and continues to be among the classic texts in
its field.
MARC S. LEVINE
Department of Radiology
University of Pennsylvania Medical Center
Philadelphia, Pennsylvania

Correction

Villablanca EJ, Cassani B, Von Andrian UH, et al. Blocking lymphocyte localization to the gastrointestinal
mucosa as a therapeutic strategy for inflammatory bowel diseases. Gastroenterology 2011;140:1776 1784.

In the above article it should be noted that Drs Eduardo J. Villablanca and Barbara Cassani contributed
equally to this work. Also, Drs Ulrich H. Von Andrian and J. Rodrigo Mora contributed equally to this work.

Correction
Hsu PI, Lai KH, Liu CP. Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with
clopidogrel alone, in patients with atherosclerosis. Gastroenterology 2011;140:791798.e2.

Dr PingI Hsu, first author in the above article, is affiliated with Kaohsiung Veterans General Hospital and
National Yang-Ming University.

Correction

Pawlotsky JM. The results of phase III clinical trials with telaprevir and boceprevir presented at the liver
meeting 2010: a new standard of care for hepatitis C virus genotype 1 infection, but with issues still
pending. Gastroenterology 2011;140:746 754.

On page 751 in the above article, below the paragraph heading, What Is the Importance of Adherence to
Treatment? The sentence: Full adherence to the protease inhibitor may be easier with telaprevir for 12
months than with boceprevir for 24 or 44 months. should be corrected to read: Full adherence to the
protease inhibitor may be easier with telaprevir for 12 weeks than with boceprevir for 24 or 44 weeks.