beclomethasone synthetic glucocorticoid that readily penetrates the

airway mucosa, used for asthma

thioridazine low potency dopamine receptor

blocker

thioridazine side effects are retinal deposits, torsades, postural

hypotension, sedation, CNS depression

valproic acid causes neural tube defects

valproic acid used to treat all kinds of seizures, as well as bipolar

disorder

1
 zolpidem binds benzodiazepine receptors,
antagonized by flumazenil

zolpidem hypnotic drug that is not a

benzodiazepine

amphetamines indirect sympathomimetic MOA

cocaine inhibits catecholamine reuptake, resulting in

cardiotox and hypertension

disulfiram inhibits aldehyde dehydrogenase, causing an

accumulation of acetaldehyde

2
flunitrazepam benzodiazepine used as a date rape
drug

lysergic acid diethylamide hallucinogenic, nausea, weakness

mescaline hallucinogenic, nausea, weakness

psilocybin hallucinogenic, nausea, weakness

marijuana lowers intraocular pressure in

glaucoma

3
 methadone treatment of opiod withdrawal

nausea, chills, sweats, lacrimation, cramps,

opioid withdrawal syndrome rhinorrhea, yawning, piloerection, diarrhea, tremor

MPTP destroys dopaminergic neurons of

the nigrostriatal tract

morphine binds mu receptors

enkephalin binds delta receptors

4
 dynorphins bind kappa receptors

opioid overdose constricted pupils, clammy skin, nausea, drowsiness,

resp depression

phencyclidine (pcp) nystagmus, hypertension, seizure

acetaminophen COX inhibitor which inhibits

prostaglandin synthesis

acetaminophen analgesic, antipyretic (but not

anti-inflammatory)

5
allopurinol suicide inhibition of xanthine
oxidase

allopurinol increases xanthine and hypoxanthine, which are less

likely to form crystals than uric acid

allopurinol slows production of uric acid, used to treat gout (and

cancer)

aspirin PGE inhibitor

aspirin predisposes to acute gastritis by inhibiting PGE in

the stomach

6
 aspirin irreversible inhibitor of
cyclooxygenase

aspirin analgesic, antipyretic, antiplatelet,

anti-inflammatory

capsaicin impairs release of substance P

capsaicin used topically for RA

celecoxib COX-2 inhibitor

7
rofecoxib COX-2 inhibitor

celecoxib sulfa drug

rofecoxib sulfa drug

colchicine inhibits microtubule assembly, and therefore

leukocyte migration and phagocytosis

colchicine leukocyte inhibitor used to treat attacks of gouty

arthritis

8
cyclosporin binds to cyclophilins and inhibits the transcription of
cytokine genes

tacrolimus binds to the immunophilin

FK-binding protein

cyclosporin impairs T cell IL-2 production, used

in transplant patients

tacrolimus used in transplant patients

etanercept a fusion product of TNF-alpha receptor and Fc

portion of antibody

9
infliximab binds and inhibits TNF-alpha

etanercept used in RA and inflammatory bowel

disease

gold salts nephrotoxic

gold salts used in RA

gold salts decreases lysosomal and

macrophage function

10
 ibuprofen similar to aspirin, lacks antiplatelet
effects

ibuprofen reversibly inhibits COX

indomethacin potent NSAID used to close a PDA

PGE used to maintain a PDA in

congenital heart disease

ketorolac parenteral NSAID

11
meperidine causes relaxation of the sphincter of
oddi

meperidine causes increased ICP

opiods causes biliary spasm

sumatriptan binds the serotonin 1D receptor

sumatriptan causes vasoconstriction of cerebral

vasculature

12
sumatriptan used for acute migraine and cluster
headaches

thalidomide used to treat SLE, multiple

myeloma, and leprosy

thalidomide suppresses production of TNF-alpha

potent
thalidomide immunosuppressant

statins may cause elevated liver enzymes

13
 statins may cause myositis

statins may cause increased CK from

skeletal muscle

reserpine enters the CNS and may cause suicidal depression

and parkinsonian symptoms

reserpine
antihypertensive agent that blocks the storage and
release of catecholamines and serotonin from
neurons

probucol decreases HDL as well as LDL

14
 probucol prevents restenosis after angioplasty

probucol acts as an antioxidant

nitroglycerin postural hypotension, headache,

flushing

nitroglycerin causes increase in cGMP in vascular

smooth muscle

niacin directly reduces secretion of VLDLs

15
 niacin increases HDL

niacin causes cutaneous flushing

vincristine M phase inhibitor

vincristine blocks microtubule polymerization

and spindle formation

ABVD adriamycin, bleomycin, vinblastine,

dacarbazine

16
 MOPP mechlorethamine, oncovin,
procarbazine, prednisone

vincristine used for lymphomas, wilms tumor,

and choriocarinomas

heparin activates AT3

heparin inactivates thrombin

protamine sulfate reverses effects of heparin

17
trastuzumab binds to receptor tyrosine kinase
Erb-B2 (HER-2)

trastuzumab used for HER-2 positive breast

cancer

tamoxifen estrogen receptor partial antagonist

tamoxifen increases risk of endometrial

carcinoma

rituximab binds CD20 antigen on B cells

18
rituximab treatment of non-hodgkin
lymphoma

prednisone triggers apoptosis

prednisone treatment for leukemia, lymphoma,

RA, asthma

paclitaxel prevents mitotic spindle breakdown

interferes with
paclitaxel anaphase

19
 paclitaxel microtubule stabilizing agent

methotrexate S phase inhibitor

methotrexate inhibits DHFR

treats
leucovorin myelosuppression

methotrexate folic acid analog

20
mercaptopurine activated by hypoxanthine-guanine

(6-MP)
phosphoribosyltransferase (HGPRT)

mercaptopurine inhibits many enzymes involved in

purine metabolism
(6-MP)

leuprolide treatment for endometriosis

leuprolide treatment for BPH and precocious

puberty

leuprolide stimulates release of FSH and LH

21
leuprolide GnRH agonist used to treat prostate
cancer

interferon alpha produced by virally infected cells to prevent infection

of adjacent cells

interferon alpha used to treat CML, malignant myeloma, kaposi

sarcoma, hairy cell leukemia

interferon alpha recombinantly produced cytokine

flutamide used to antagonize residual

androgens after orchiectomy

22
 flutamide side effects include gynecomastia
and libido changes

flutamide androgen receptor antagonist

fluorouracil S phase antimetabolite

causes
fluorouracil myelosuppression

fluorouracil inhibits thymidylate synthase

23
fluorouracil used to treat colon cancer and basal
cell carcinoma

etoposide G2 phase inhibitor

etoposide causes double stranded breaks in

DNA

etoposide inhibits topoisomerase II

etoposide used to treat small cell carcinoma of the lung and

prostate and testicular cancers

24
doxorubicin intercalates in DNA to reduce
replication and transcription

doxorubicin causes dilated cardiomyopathy

daunorubicin used to treat AML

cyclophosphamide causes hemorrhagic cystitis

alkylating agent used to treat

cyclophosphamide cancers

25
 cisplatin alkylating agent

cisplatin causes nephrotoxicity and acoustic

nerve damage

carmustine alkylating agent that causes DNA cross-linking and

strand breaks

carmustine used to treat brain tumors, highly lipophilic

nitrosourea drug

bleomycin mixture of glycoproteins that produce free radicals

upon binding DNA

26
bleomycin causes strand breaks in DNA

bleomycin G2 phase inhibitor

bleomycin can cause pulmonary fibrosis

anastrozole inhibitor of steroid synthesis

anastrozole inhibits conversion of

androstenedione to estrone

27
 blocks conversion of cholesterol to
aminoglutethimide pregnenolone

anastrazole aromatase inhibitor

zidovudine inhibits viral reverse transcriptase

zidovudine chain terminator

zidovudine given to prevent transmission of

HIV to neonates

28
vancomycin used to treat MRSA

vancomycin used to treat c. difficile

vancomycin rapid IV infusion causes red man

syndrome

TMP-SMX blocks folate synthesis

TMP-SMX can cause megaloblastic anemia

29
 TMP-SMX do not give to pts with G6PDH
deficiency

trimethoprim blocks DHFR

sulfamethoxazole blocks dihydropteroate synthase

tetracycline inhibits 30s ribosome

tetracycline bacteriostatic drug

30
 tetracycline CI in pregnant women due to bone dysplasia and
dental enamel defects

streptogramins p450 inhibitor

arthralgias and
streptogramins myalgias

streptogramins used to treat MRSA and VRE

rifampin inhibits DNA-dependent RNA

polymerase

31
rifampin imparts red-orange color to
secretions

ribavirin guanosine analog

ribavirin inibits steps in RNA synthesis

ribavirin used to treat viral hemorrhagic

fevers and hepatitis C

ribavirin used to treat RSV

32
 quinine blocks DNA replication and RNA transcription in p.
falciparum within RBCs

quinine causes cinchonism

cinchonism headache, vertigo, blurry vision,

tinnitus

mefloquine used for prophylaxis of p. falciparum

due to low SE

quinine used for malaria

33
 stimulates nicotinic receptors in
pyrantel pamoate nematodes

praziquantel used for fluke and tapeworm

infections

polymyxin b cationic detergent that disrupts

bacterial membranes

polymyxin b causes neurotoxicity and acute

tubular necrosis

polymyxin b only used topically

34
penicillins inhibits transpeptidation step in bacterial cell wall
synthesis

oseltamivir neuraminidase inhibitor that

prevent viral spreading

used against influenza

oseltamivir a

nystatin disrupts fungal membrane permeability by binding

to ergosterol

nystatin used to treat oral candidiasis and

diaper rash

35
nitrofurantoin can cause hemolysis in G6PDH
deficient patients

nitrofurantoin can accumulate to toxic levels in patients with renal

failure

nitrofurantoin urinary antiseptic that requires

acidification

nifurtimox used to treat chagas disease

NNRTI used to treat

nevirapine HIV

36
 neomycin used to treat hepatic encephalopathy

neomycin prevents accumulation of

nitrogenous microbial metabolites

metronidazole activated by anaerobes and parasites

metronidazole interferes with nucleic acid synthesis

metronidazole used to treat amebiasis, trichomoniasis, giariasis,

and c. diff

37
 methicillin bulky R-group prevents degradation
by penicillinase

nafcillin bulky R-group prevents degradation

by penicillinase

dicloxacillin bulky R-group prevents degradation

by penicillinase

methi, naf, diclox beta lactams

mebendazole inhibits microtubule synthesis and glucose uptake by

helminths

38
mebendazole used to treat pinworms

albuterol selective b2 agonist

atenolol selective b1 blocker

acebutolol selective b1 blocker

metoprolol selective b1 blocker

39
 depresses cough center in the
detromethrophan medulla

metoclopramide facilitates acetylcholine while blocking dopamine in

the enteric nervous system

metoclopramide SE are sedation, diarrhea,

extrapyramidal symptoms

metoclopramide prokinetic agent used to block

emesis

metoclopramide blocks D2 receptors in the area

postrema

40
misoprostol PGE analog

misoprostol decreases gastric acid production, increases mucus

production

misoprostol eicosanoid preparation used for pts

taking lots of NSAIDs

omeprazole H/K ATPase inhibitor

ondansetron serotonin-3 inhibitor that acts at the

area postrema

41
 sucralfate requires acidic environment to
polymerize

sucralfate cannot be used with antacids or H2

blockers

folic acid will correct anemia but not neuro sx associated with
b12 deficiency

EPO recombinant drug used for anemia

orally active inhibitor of

aminocaproic acid plasminogen activation

42
aminocaproic acid inhibits fibrinolysis

used for acute bleeding in

aminocaproic acid hemophilic patients

abciximab antibody against glycoprotein 2b/3a

receptor

abciximab prevents platelet activation

abciximab anticoagulant preventing restenosis

after angioplasty

43
benztropine antimuscarinic

benztropine CI are prostatic hyperplasia, GI

obstruction, glaucoma

benztropine antimuscarinic used to treat tremors and rigidity in

parkinsons, but does nothing for bradykinesia

RhoGAM antibody to Rh(D) antigen that

opsonizes

probenecid competes with uric acid for reabsorption in the

proximal tubule

44
 probenecid inhibits secretion of weak acids

sulfinpyrazone acts simliarly to probenecid

methylsergide blocks serotonin receptors

causes fibroplasia of
methylsergide retroperitoneum and
subendocardium

methylsergide used to prevent migraines

45
 daclizumab binds IL-2 receptor on activated T
cells

daclizumab used for patients with renal

allografts

bromocriptine D2 agonist

bromocriptine inhibits PRL release

inhibit histamine binding to H1

diphenhydramine receptors

46
diphenhydramine causes drowsiness

used for allergies and motion

diphenhydramine sickness

cromolyn sodium stabilizes mast cell membrane

lithium inhibits IP3 and DAG

lithium causes tremor, hypothyroidism,

polydipsia, polyuria

47
 stimulates the release of
methylphenidate catecholamines

phenytoin inducer of p450

carbamazepine inducer of p450

griseofulvin inducer of p450

rifampin inducer of p450

48
 barbiturates inducer of p450

penicillins bactericidal

cephalosporins bactericidal

vancomycin bactericidal

aminoglycosides bactericidal

49
 fluoroquinolones bactericidal

metronidazole bactericidal

calcium channel causes cutaneous flushing

blockers

adenosine causes cutaneous flushing

vancomycin causes cutaneous flushing

50
metronidazole causes disulfiram-like reaction

cephalosporins causes disulfiram-like reaction

procarbazine causes disulfiram-like reaction

nitrous oxide has a high MAC

phenelzine MAOI

51
tranylcypromine MAOI

isocarboxazid MAOI

MAOI + SSRI serotonin syndrome

MAOI inhibits breakdown of amine

neurotransmitters

mebendazole microtubule inhibitor

52
thiabendazole microtubule inhibitor

paclitaxel microtubule inhibitor

vincristine microtubule inhibitor

colchicine microtubule inhibitor

griseofulvin microtubule inhibitor

53
hydralazine SLE like syndrome

procainamide SLE like syndrome

isoniazid SLE like syndrome

phenytoin SLE like syndrome

massive hepatic
halothane necrosis

54
 massive hepatic
acetaminophen necrosis

massive hepatic
valproic acid necrosis

cimetidine p450 inhibitor

ketoconazole p450 inhibitor

erythromycin p450 inhibitor

55
 cimetidine gynecomastia

ketoconazole gynecomastia

spironolactone gynecomastia

bleomycin pulmonary fibrosis

amiodarone pulmonary fibrosis

56
 busulfan pulmonary fibrosis

ototoxic and
aminoglycosides
nephrotoxic

ototoxic and
loop diuretics nephrotoxic

ototoxic and
cisplatin nephrotoxic

vancomycin mildly ototoxic and nephrotoxic

57
penicillamine used to treat wilson disease

penicillamine used to treat RA

penicillamine used to treat copper toxicity bc it is a

chelator

anticholinesterases used in chemical

organophosphates warfare

pralidoxime antidote for anticholinesterases such

as organophosphates

58
 naloxone mu opioid receptor antagonist

naloxone used to treat opioid overdose

phenobarbital binds GABA receptors

phenobarbital increases the duration of chloride

channel opening

phenobarbital used to treat tonic-clonic seizures

and crigler-najjar

59
phenytoin interferes with folate absorption

phenytoin SE are gingival hyperplasia, hirsutism, anemia, and

birth defects

phenytoin class 1b antiarrhythmic

risperidone blocks D2 and serotonin-2 receptors

risperidone causes high sedation

60
risperidone atypical antipsychotic with lots of
extrapyramidal SE

ropinirole forestalls the use of levodopa in

parkinson's disease

methanol causes damage by being converted to formaldehyde

in the liver

methanol retinal damage, blindness, metabolic

acidosis, coma

flumazenil antagonizes benzodiazepines and

zolpidem

61
flumazenil used for benzodiazepine overdose

ethylene glycol causes metabolic acidosis and precipitation of

oxalate crystals in the kidney

dimercaprol chelates metals to keep them from

damaging proteins

succimer orally active metal chelator

dimercaprol used to treat heavy metal poisoning

62
 digibind fab fragment antibody

deferoxamine rapid infusion causes hypotensive

shock

deferoxamine used to treat acute iron toxicity

dantrolene decreases the release of calcium from the

sarcoplasmic reticulum

dantrolene used to treat malignant

hyperthermia

63
selegiline inhibits MAO-B

MAO-B degrades dopamine

selegiline inhibits degradation of dopamine in CNS, used with

levodopa for parkinson's

thiopental ultra-short acting barbiturate used to induce surgical

anesthesia

alprazolam intermediate-acting benzodiazepine used for panic

disorder and phobias

64
 protects against fulminant hepatic
n-acetylcysteine failure

n-acetylcysteine used for acetaminophen overdose

carvedilol used for CHF

carvedilol nonselective beta blocker and

alpha-1 blocker

blocks sodium
amiodarone channels

65
 amiodarone corneal microdeposits

amiodarone class III antiarrythmic

adenosine short acting agent given IV for AV

nodal arrhythmias

spironolactone potassium sparing diuretic

spironolactone aldosterone antagonist

66
spironolactone functions at the collecting tubule

nitroprusside stimulates guanyl cyclase

nitroprusside increases cGMP in vascular smooth

muscle

minoxidil direct-acting vasodilator

minoxidil used topically bc of benefit of

hypertrichosis

67
cholestyramine bind bile acids to prevent
enterohepatic recycling

fexofenadine nonsedating antihistaminic

loratadine nonsedating antihistaminic

ipratropium dry mouth side effect

ipratropium antimuscarinic for COPD and

asthma

68
salmeterol may cause tremors and arrhythmias

theophylline methylxanthine used for asthma

theophylline inhibits phosphodiesterase

theophylline inhibits conversion of cAMP to AMP

octreotide used to treat carcinoid, gastrinoma, somatotropic

pituitary adenoma

69
 inhibits iodination step of thyroid
propylthiouracil hormone synthesis

methimazole same as PTU but crosses placenta

and enters breast milk

estrogen partial
raloxifene agonist

raloxifene does not increase the risk of

endometrial cancer

tamoxifen increases risk of endometrial cancer

70
 rapid onset
repaglinide sulfonylurea

repaglinide binds potassium channels to

facilitate insulin release

glitazones increase insulin sensitivity

glitazones stimulate PPAR-gamma receptor

troglitazone hepatotoxic

71
sulfonylureas stimulate closure of potassium
channels

sulfonylureas glyburide and glipizide

sulfonylureas cause release of preformed insulin

acyclovir used to treat herpes

acyclovir guanosine analog

72
 acyclovir activated by thymidine kinase of the
virus it treats

acyclovir functions as a chain terminator when incorporated

into viral DNA

amantadine prophylaxis against influenza A and

rubella

amantidine inhibits fusion of viral particles within endosome of

the cell

amantidine not effective against influenza B

73
 amantidine binds to M2 protein

amphotericin B disrupts fungal membranes by

binding ergosterol

mifepristone blocks binding of progesterone to

cytoplasmic receptors

ampicillin extended spectrum penicillin used to

treat gram negatives

aztreonam b-lactamase resistant monobactam

74
aztreonam used only with aminoglycosides
against gram negative rods

aztreonam cannot be used against gram

positives or anaerobic bacteria

bacitraicin inhibits bacterial cell wall synthesis

piperacillin used against enterobacter and

pseudomonas

carbenicillin used against enterobacter and

pseudomonas

75
 ticarcillin used against enterobacter and
pseudomonas

ceftriaxone used for septic meningitis

used to treat
cefixime gonnorhea

chloramphenicol gray baby syndrome in babies deficient in hepatic

gluconosyltransferase

chloramphenicol aplastic anemia

76
fludrocortisone used in postadrenalectomy therapy

chloroquine primary drug for acute malaria

chloroquine disrupts hemoglobin breakdown, with toxic

accumulation of heme in RBC

beta lactamase
clavulanic acid
inhibitor

beta lactamase
sulbactam inhibitor

77
 beta lactamase
tazobactam inhibitor

clindamycin bacteriostatic at the 50s ribosome

treatment of
clindamycin bacteroides

didanosine (ddI) dose-limiting pancreatitis

lamivudine inhibits reverse transcriptase of

hepatitis B

78
erythromycin bacteriostatic inhibitor of 50s

erythromycin macrolide

azithromycin macrolide

clarithromycin macrolide

erythromycin GI irritation and acute cholestatic

hepatitis

79
metformin biguanide compound

metformin increases peripheral glycolysis

clomiphene blocks negative feedback at the

pituitary

cosyntropin used for diagnosis of addison's

disease

danazol inhibitor of p450

80
 danazol used for endometriosis and fibrocystic disease of the
breast

desmopressin selective V2 agonist

vasopression V1 and V2 agonist

vasopressin used to treat esophageal varices

DES clear cell carcinoma of the vagina in

daughters

81
 lowers risk of coronary disease, slows osteoporosis,
ethinyl estradiol/mestranol ameliorates hot flashes

HRT increased risk of breast and ovarian

cancer

zileutin inhibits leukotriene synthesis

LTD4 and LTE4

monteleukast antagonist

acarbose inhibits a-galactosidase

82
 bisphosphonates esophageal ulcerations

bromocriptine used to treat hyperprolactinemia

due to pituitary adenoma

bromocriptine ergot alkaloid

diphenoxylate suppress GI motility

loperamide suppress GI motility

83
 cisapride stimulates peristalsis by release of Ach from
myenteric plexus

cisapride long QT

magnesium hydroxide laxative antacid

aluminum hydroxide constipating antacid

ipecac syrup acts to stimulate chemoreceptor

trigger zone of the medulla

84
 cimetidine gynecomastia and galactorrhea

cimetidine p450 inhibitor

calcium carbonate hypercalcemic alkalosis

calcium carbonate renal calculi

bismuth subsalicylate used with metronidazole and tetracycline for PUD

caused by h.pylori

85
 warfarin interferes with vitamin K dependent
clotting factors

alteplase converts fibrin-bound plasminogen

to plasmin

ticlopidine platelet antiaggregant

ticlopidine interferes with binding of fibrin to Gp2b/3a receptor

on platelets

streptokinase catalyzes conversion of plasminogen

to plasmin

86
fluconazole inhibits formation of ergosterol

fluconazole prophylaxis against cryptococcus

neoformans

fluconazole used to treat oral candidiasis

fluoroquinolones bactericidal inhibitor of DNA gyrase

fluoroquinolones used for gram negative rods, some gram positives,

and neisseria

87
fluoroquinolones bad for cartilage

sargramostim recombinant GM-CSF

filgrastim G-CSF

hydroxyurea used for sickle cell crisis

hydroxyurea increases levels of HbF

88
hydroxyurea inhbits DNA synthesis by blocking conversion of
ribonucleotides to deoxyribonucleotides

foscarnet treats CMV

foscarnet inhibits viral DNA polymerase

ganciclovir metabolized by viral transferases

ganciclovir requires phosphorylation by viral

kinases to work

89
ganciclovir guanosine analog converted by CMV
to triphosphorylated form

ganciclovir SE: neutropenia, leukopenia,

thrombocytopenia

griseofulvin keratinized tissue

griseofulvin ringworm

griseofulvin binds tubulin

90
carbapenem given with cliastatin

carbapenem used against gram positive cocci, gram negative rods,

and anaerobes

ritonavir inhibit protease in the HIV pol gene

isoniazid inhibits synthesis of mycolic acid

isoniazid SE neuritis and hepatitis

91
ethambutol TB

pyrazinamide TB

rifampin TB

streptomycin TB

sulfonamides stevens-johnson

92
ethosuxamide stevens-johnson

lamotrigine stevens-johnson

penicillins erythema multiforme

barbiturates erythema multiforme

salicylates erythema multiforme

93
hydantoins erythema multiforme

antimalarials erythema multiforme

sulfonamides G6PDH

isoniazid G6PDH

primaquine G6PDH

94
tetracycline photosensitivity

amiodarone photosensitivity

sulfonamides photosensitivity

bethanechol muscarinic agonist

carbachol nicotinic and muscarinic agonist

95
 ephedrine ma-huang

adrenergic antagonist (alpha

phenoxybenzamine receptors)

phentolamine used in diagnosing

pheochromocytoma

ivermectin onchocera volvulus and

strongyloides stercoralis

ivermectin increases GABA transmission in the

worm

96
ketoconazole interfere with fungal cell wall
synthesis

pilocarpine treatment of glaucoma

pilocarpine muscarinic agonist

prazosin first dose syncope

prazosin miosis

97
pyridostigmine used for tubocurarine toxicity

scopolamine competitive cholinergic antagonist

used for motion sickness

succinylcholine muscle relaxant

nicotinic agonist that opens sodium

succinylcholine channels

tubocurarine nondepolarizing neuromuscular

ganglionic blockers

98
acetazolamide inhibits carbonic anhydrase in the proximal
convoluted tubule

acetazolamide metabolic acidosis

acetazolamide give to alkalinize the urine in aspirin

toxicity

amiloride block sodium channels in the

cortical collecting tubules

amiloride hyperkalemic metabolic acidosis

99
 captopril inhibit breakdown of bradykinin

ketamine should be given with

benzodiazepines

gabapentin partial seizures

ethosuxamide inhbits T-type calcium channels

entacapone inhibits conversion of levodopa to

3-0-methyldopa

100
 HCTZ hypokalemia, alkalosis,
hyperuricemia, hyperlipidemia

captopril functions at the collecting tubules

losartan functions at the collecting tubules

losartan CI in pregnancy

captopril CI in pregnancy

101