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LEMBAR PENGESAHAN

Nama : Ayu Enggaringtyas, S.Ked


No. Stambuk : N. 111 14 064
Program Studi : Pendidikan Dokter
Fakultas : Kedokteran
Universitas : Tadulako
Judul Refarat : Basic Science Tumor
Bagian : Telinga Hidung Tenggorokan Kelapa Leher

Telah menyelesaikan tugas dalam rangka kepaniteraan klinik pada


bagian Ilmu Kesehatan Telinga Hidung Tenggorokan-Kepala Leher Fakultas
Kedokteran Universitas Tadulako.

Palu, Agustus 2017


Mengetahui

Pembimbing Co-Assisten

dr. Christian Lopo, Sp.THT-KL Ayu Enggaringtyas, S.Ked

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DAFTAR ISI

1. BAB I PENDAHULUAN.................................................................................1
2. BAB II BASIC SCIENCE TUMOR...............................................................2
3. DEFINISI TUMOR..........................................................................................2
4. KLASIFIKASI TUMOR.................................................................................2
1. TUMOR NEOPLASMA............................................................................2
A. Neoplasma Benigna (Tumor
Jinak)......................................................................................................3
a. Definisi Neoplasma Beingna (Tumor Jinak)....................................3
b. Ciri-Ciri Neoplasma Benigna (Tumor Jinak)...................................3
c. Proses Pertumbuhan Neoplasma Benigna (Tumor Jinak)................4
1) Sel Tumor...................................................................................4
2) Induksi........................................................................................6
3) Invasi Lokal................................................................................7
4) Metastasis...................................................................................7
d. Jenis Neoplasma Benigna (Tumor Jinak).........................................8
1) Neoplasma Benigna Berasal Dari Mesenkimal..........................8
a) Fibroma................................................................................8
b) Lipoma.................................................................................9
c) Osteoma................................................................................9
d) Chondroma.........................................................................10
e) Leiomyoma........................................................................11
f) Rhabdomioma....................................................................12
g) Hemangioma......................................................................12
2) Neoplasma Benigna Berasal Dari Epitel..................................13
a) Adenoma............................................................................13
b) Papilloma............................................................................14
c) Polip...................................................................................15
d) Kistadenoma.......................................................................15

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B. Neoplasma Maligna (Tumor Ganas)....................................................16
a. Definisi Neoplasma Maligna (Tumor Ganas)................................16
b. Ciri-Ciri Neoplasma Maligna (Tumor Ganas)...............................16
c. Proses Pertumbuhan Neoplasma Maligna (Tumor Ganas)............16
1) Sel Tumor.................................................................................16
2) Induksi......................................................................................19
3) Invasi Lokal..............................................................................20
4) Metastasis.................................................................................20
d. Jenis Neoplasma Maligna (Tumor Ganas).....................................24
1) Neoplasma Maligna Berasal Dari Mesenkimal........................24
a) Fibrosarkoma......................................................................24
b) Liposarkoma.......................................................................24
c) Osteosarkoma.....................................................................25
d) Chondrosarkoma................................................................26
e) Leiomyosarkoma................................................................26
f) Rhabdomiosarkoma............................................................27
g) Angiosarkoma....................................................................27
2) Neoplasma Maligna Berasal Dari Epitel..................................28
a) Adenokarsinoma................................................................28
b) Suamous cell karsinoma.....................................................28
c) Cystadenokarsinoma..........................................................29
2. TUMOR NON NEOPLASMA
1. Definisi Tumor Non Neoplasma..........................................................30
2. Jenis Tumor Non Neoplasma...............................................................30
a. Kista................................................................................................30
1) Definisi Kista...........................................................................30
2) Jenis Kista................................................................................30
a) Kista dermoid....................................................................30
b) Kista ateroma.....................................................................31
c) Kista epidermal..................................................................31
b. Radang/Inflamasi............................................................................31

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1) Definisi Radang.......................................................................31
2) Tanda Radang..........................................................................32
a) Rubor.................................................................................32
b) Kalor..................................................................................32
c) Dolor..................................................................................32
d) Tumor................................................................................32
c. Hipertrofi........................................................................................32
1) Definisi Hipertrofi...................................................................32
d. Hiperplasia......................................................................................33
1) Definisi Hiperplasia.................................................................33
2) Proses Terjadinya Hiperplasia.................................................33
3) Contoh Hiperplasia..................................................................34
5. ETIOLOGI DAN PREDISPOSISI TUMOR...............................................35
A. Karsinogen Kimiawi...................................................................................35
B. Karsinogen Fisik.........................................................................................35
C. Karsinogen Virus........................................................................................36
D. Parasit.........................................................................................................36
E. Inflamasi Kronik.........................................................................................36
F. Faktor Genetik............................................................................................36
G. Peranan Hormon.........................................................................................37
H. Faktor Gaya Hidup.....................................................................................37
I. Sunat Dan Fimosis......................................................................................38
J. Penurunan Imunitas....................................................................................38
6. DAFTAR PUSTAKA.....................................................................................39

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