2
message of
the director
-
ly due to a perfect combination Another project moving
forward was the low impact me-
The laboratory has an excellent
infrastructure for scale up of etha- Prototypes of the base machine
nol production technologies and and harvest heads of the Control-
3
Aerial view of CNPEM campus in Campinas-SP, with architectural project of the new
synchrotron light source (Sirius), under construction.
4
contents
CNPEM
The Brazilian Center for Research in Energy and Materials (CNPEM), located
5
Facade of the CTBE
main building, Lab
created with the aim
of contributing to the
Brazilian competi-
tiveness in industrial
production and con-
version of biomass
into fuels and other
high added-value
compounds.
6
about CTBE
main goal of the Laboratory is to The Pilot Plant for Process De-
contribute to the Brazilian com- -
petitiveness in production and in-
dustrial conversion of biomass into environment in Brazil allows the
-
electricity and compounds derived
biomass conversion into cellulosic
- ethanol and other products pre-
and technical support are offered One the other hand the
for Brazilian and foreign users that Laboratorys internal research
work with production, characteri- agenda is dedicated to agricultu-
zation and processing of biomass ral, industrial, technological assess-
and derivatives as well as studies ment, sustainability and basic rese-
of functional biology, biotechnolo- arch of biomass/bioproducts areas,
Mission Vision
Contribute to the advance- Being a National Laboratory
- of excellence in research, develo-
cal knowledge in the production, pment, innovation and technology
conversion and use of biomass for transfer in the biomass and bioe-
energy and materials, through re-
search, development, innovation
7
High Quality Human
Capital and Publications
Sophisticated
R&D Environment
Events: Networking
and Dissemination
of Results
8
at a glance
-
It houses three buildings
2
- It has published over 230
cipal, which includes laborato- -
ries and researchers rooms, Pilot
Plant for Process Development It signed 13 cooperation
- agreements with companies in
-
ture designed for technology sca- events in the bioenergy area, es-
le up, with the purpose of trans- pecially the annual workshops
ferring processes from laboratory
-
It works in the establishment cane Physiology for Agronomic
of low impact mechanization on
9
our history
November 2008
Beginning of the construction of
CTBE facilities. Three buildings
were constructed totaling
approximately 9,000 m2, in the
Campus of CNPEM.
10
January 22, 2010 August 2013
Opening of the CTBE, which
counted with the presence of of a biotechnological process
former President of Brazil, Luiz scale up in the Pilot Plant that
lncio Lula da Silva, and other made bioreactors and other
regional and national authorities. utilities remained in uninterrupted
The ceremony also celebrated operation during seven
months, certifying the proper
partnerships of the Laboratory. commissioning of the facility.
May 2011
Signing of agreement with BNDES
(Funtec line) which provides
11
Hydrolysis reactor of
biomass in labora-
tory scale. It is used
of enzyme cock-
tails developed for
industrial use in the
second generation
ethanol production
12
R&D facilities
Agricultural Prototypes
Laboratories and Pilot Plant of the Labotatory (LPA)
There it is developed machi-
nery necessary for the implemen-
Pilot Plant for Process tation of low impact mechanization
Development (PPDP)
Professionals use the Pilot
-
and demonstrate, in semi-indus-
it is developed at LPA a Controlled
and stability of technological rou-
tes for production of ethanol and
other compounds derived from
13
Panoramic image of the Pilot Plant for Process Development (PPDP) of the CTBE, used for
scale up of technological routes for the production of ethanol and other compounds derived
from biomass.
- -
ment for monitoring bioprocesses
-
cabinets, microbiological gree-
-
14
The following laboratories In- such as functional genomics,
metagenomics, transcriptomics,
proteomics, systems biology,
- genetics and metabolic engine-
ering for bio-prospecting of mi-
croorganisms and enzymes and
- for understanding the molecular
mechanisms involved in the plant
biomass conversion by enzymatic
Functional Biology,
Biotechnology and also used in order to improve the
Biophysics Laboratories catalytic performance of charac-
Plant physiology studies
analyze the relationship between Integrate this cluster of labs
photosynthesis and biomass ac- -
cumulation, assessment of water
-
-
-
In the molecular biology area
scientists employ approaches,
15
low impact mechanization
conservation agriculture
plant physiology
applied microbiology and biotechnology
analytical tools for biomass and derivatives
computational and system biology
enzyme production and lignocellulosic hydrolysis
16
internal research
Biomass Processing
Biomass Production
to convert biomass into fuels, new
and solutions focused on the evo- materials, and chemicals for seve-
lution of economic and environ-
mental aspects of the agricultural use biochemical, metabolic and
mechanization of sugarcane, with
emphasis on production costs, -
-
group develops a Controlled Tra- cess proof-of-concepts at labora-
17
metabolites present in plant tissues.
Integrated Evaluation
18
Microscopic image of the cross section of a sugarcane stem. A deep knowledge of this molecular
Functional Biology, -
Biotechnology and physics abd Analitical Methods for
Biophysics
It aims unravel the mechanis- and Computational Biology and
ms of plant production and growth,
19
CTBE develops
research in the ag-
ricultural, industrial,
technology assess-
ment, sustainability
and basic research
of biomass/ bio-
products cycle,
either independently
or in partnership
with the main bioen-
ergy companies and
research institutions.
20
research highlights
-
nificant impacts in several areas
related to the biomass and bio-
- -
chers effort contribute to improve served domain of glycoside hydro-
agricultural, industrial and sustai- lases family 5 and a carbohydrate-
nability indicators of the produc-
21
The main production operations
of sugarcane are related to planting
and harvesting and mechanical ac-
tions involve heavy mechanical han-
dling actions of biomass, inputs and
-
ment seeks to reduce the severe
restrictions that the current harves-
-
mic management of the plantation,
improving productivity and econo-
mic and environmental sustainabili-
22
Yeast with High
Pseudozyma brasiliensis
is able to metabolize five-carbon
sugars and secrete xylanase with
activity 20 times higher than the
enzyme extract from Aspergillus
niger, fungus notoriously recog-
nized by the expression of this
23
-
Trichoderma harzianum
enzymatic complex isolated from
Amazon biome with high biotech-
nological potential for the second
-
ted in the publication of a patent
-
derstanding the cellulolytic system of Tri-
choderma harzianu P49P11 and enhancing
saccharification of pretreated sugarcane
bagasse by supplementation with pectina-
se and -l-arabinofuranosidase. Bioresour-
ce Technology, 131, 500-507.
24
Mechanical harvesting has re-
placed manual cutting with bur-
ning of sugarcane due to, among
other factors, greenhouse gases
25
-
-
-
-
ration plant, alcoholchemistry for
butanol production, thermoche-
26
-
ticipated in the development of a
-
-
plied to unicellular Clamydomonas
alga and to the vascular plant Ara-
-
sionals of the Laboratory have deve-
loped a computational platform for
the analysis of such data, facilitating
the handling of information by bio-
logists without training in program-
27
selected
publications
Bioresource Technology,
relevant success indicator of the
warming and human health im-
pacts related to Brazilian sugarca-
ne ethanol production considering -
Applied sion pretreatment of sugarcane
Energy straw for enzymatic hydrolysis of
cellulose for production of second
generation ethanol and value-ad-
Bioresource Tech-
nology
-
-
derstanding the cellulolytic system
of Trichoderma harzianum
-
of pretreated sugarcane bagasse
by supplementation with pectina- and second generation ethanol and
se and Applied
28
Energy
Bioresource Technology
-
Butanol production in a first-ge- -
neration Brazilian sugarcane bio- ging of sugarcane bagasse using
Industrial
Crops and Products
Bioresource Technology
-
-
- Increased production of cellulases
- and xylanases by Penicillium echi-
nulatum -
Bioresource Tech-
- nology
plication of feruloyl esterase from
Aspergillus clavatus Applied Mi-
crobiology and Biotechnology -
-
-
re and function of a novel cellulase
Utilization of pentoses from sugar- 5 from sugarcane soil metageno-
PloS One
29
High-performance
-
-
30
professionals
-
ployees, including contractors and Carlos Alberto Labate
and Biotechnology
31
Learn about the professional
education and work developed by
some of the leading researchers of
-
cular biology, biochemistry, Omics
-
32
Chemist, works in the area of pre-treatment and physicochemical analyzes of sugarcane bagasse for bio-
ethanol production.
-
- -
ds a doctorate degree in soils and ty of Uberlndia, with a Masters and
PhD in Physico-Chemistry from the
a postdoctoral in the use of fertili- -
zers enriched in 15N, 34 10
B in the ded exchange scholarship doctorate
assessment of management form
-
researcher visitor at the University
-
33
Graduated in chemistry, works with pre-treatment and chemical characterization of biomass. His doctoral the-
sis won the Capes Grand Prize of Thesis.
-
use change and sustainable agri-
34
Carlos Driemeier
Physicist, expert in nanostructure of lignocellulosic biomass and characterization methods related to nano-
structural variability.
Carlos Driemeier
-
ation and doctorate degree in the
-
-
archer at Parthenope University of an exchange scholarship doctora-
35
Biomass Physical
36
innovation
37
-
mum non-financial contribution research cover the development
of Base Machine of the Controlled
BP: -
high alcoholic content sugar wi- vest heads, agronomic evaluation
of the precise sugarcane planting
38
Patents
-
-
-
-
Trichoder-
of Parallel Plates for Alignment of
ma harzianum -
39
Workshop
promoted by the
CTBE in Decem-
ber 2013, brought
together representa-
tives from research
institutions, com-
panies and govern-
ments of Brazil and
Denmark. They ex-
plore possibilities for
joint developments
of technologies that
exploit the concept
40
events and training
programs
41
Speaker presentation at the fourth edition of the Workshop on Second Generation Bioethanol:
Enzymatic Hydrolysis, in CTBE Auditorium.
Short course of -
Thermoporometry Applied
to Lignocelluloses
July, 25th
Programs for Students
42
Participants for the Summer School Program, in which graduate students from all over Latin
America come annually to the CNPEM to develop research projects during the months of Janu-
ary and February.
(PUE): high school and under- period which the selected stu-
graduate students may partici-
There are, on average, 20 vacan-
like Physics, Chemistry, Biology,
-
tion Scholarship Program (PIBIC):
-
arships of the National Council for
-
Summer School Program:
Intended for undergraduate stu- registrations takes place once a
dents from Latin America and the year, with an average of 20 stu-
Caribbean who have completed at -
tion of twelve months, beginning
43
2013 in two pages
44
At the end of the year, circulation In December, the Laboratory
in patio and deployment of
automation of base machine of for external research, through
on-line submission proposals on
(ETC) were initiated. Their harvest
heads were also improved Process Development Labs (LDP)
in experiments performed in and Pilot Plant.
45
Brazilian Center for Research in
Energy and Materials (CNPEM)
Edition:
Graphic Design and Layout: William Barbosa / ACO
Printing:
Photos:
46
47
48